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Items: 1 to 20 of 106

1.

Biological targets of antitumor indolocarbazoles bearing a sugar moiety.

Prudhomme M.

Curr Med Chem Anticancer Agents. 2004 Nov;4(6):509-21. Review.

PMID:
15579016
2.

Structure-activity relationships in a series of substituted indolocarbazoles: topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties.

Pereira ER, Belin L, Sancelme M, Prudhomme M, Ollier M, Rapp M, Sevère D, Riou JF, Fabbro D, Meyer T.

J Med Chem. 1996 Oct 25;39(22):4471-7.

PMID:
8893841
3.

Indolocarbazole glycosides in inactive conformations.

Facompré M, Carrasco C, Vezin H, Chisholm JD, Yoburn JC, Van Vranken DL, Bailly C.

Chembiochem. 2003 May 9;4(5):386-95.

PMID:
12740810
4.

Syntheses, biochemical and biological evaluation of staurosporine analogues from the microbial metabolite rebeccamycin.

Anizon F, Moreau P, Sancelme M, Voldoire A, Prudhomme M, Ollier M, Sevère D, Riou JF, Bailly C, Fabbro D, Meyer T, Aubertin AM.

Bioorg Med Chem. 1998 Sep;6(9):1597-604.

PMID:
9801830
5.

Syntheses and biological activities of rebeccamycin analogues with uncommon sugars.

Zhang G, Shen J, Cheng H, Zhu L, Fang L, Luo S, Muller MT, Lee GE, Wei L, Du Y, Sun D, Wang PG.

J Med Chem. 2005 Apr 7;48(7):2600-11.

PMID:
15801850
6.

DNA targeting of two new antitumour rebeccamycin derivatives.

Facompré M, Baldeyrou B, Bailly C, Anizon F, Marminon C, Prudhomme M, Colson P, Houssier C.

Eur J Med Chem. 2002 Dec;37(12):925-32.

PMID:
12660017
7.

Enhanced binding to DNA and topoisomerase I inhibition by an analog of the antitumor antibiotic rebeccamycin containing an amino sugar residue.

Bailly C, Qu X, Anizon F, Prudhomme M, Riou JF, Chaires JB.

Mol Pharmacol. 1999 Feb;55(2):377-85.

PMID:
9927631
8.

Indolocarbazole antitumour compounds by combinatorial biosynthesis.

Salas JA, Méndez C.

Curr Opin Chem Biol. 2009 Apr;13(2):152-60. doi: 10.1016/j.cbpa.2009.02.003. Epub 2009 Feb 27. Review.

PMID:
19251468
9.

Rebeccamycin analogues bearing amine substituents or other groups on the sugar moiety.

Anizon F, Moreau P, Sancelme M, Laine W, Bailly C, Prudhomme M.

Bioorg Med Chem. 2003 Aug 15;11(17):3709-22.

PMID:
12901916
10.

Semi-synthesis, topoisomerase I and kinases inhibitory properties, and antiproliferative activities of new rebeccamycin derivatives.

Moreau P, Gaillard N, Marminon C, Anizon F, Dias N, Baldeyrou B, Bailly C, Pierré A, Hickman J, Pfeiffer B, Renard P, Prudhomme M.

Bioorg Med Chem. 2003 Nov 17;11(23):4871-9.

PMID:
14604648
11.

Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives.

Sánchez C, Méndez C, Salas JA.

J Ind Microbiol Biotechnol. 2006 Jul;33(7):560-8. Epub 2006 Feb 21. Review.

PMID:
16491358
12.

4'-N-methyl-5'-hydroxystaurosporine and 5'-hydroxystaurosporine, new indolocarbazole alkaloids from a marine Micromonospora sp. strain.

Hernández LM, Blanco JA, Baz JP, Puentes JL, Millán FR, Vázquez FE, Fernández-Chimeno RI, Grávalos DG.

J Antibiot (Tokyo). 2000 Sep;53(9):895-902.

13.

Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine.

Nakano H, Omura S.

J Antibiot (Tokyo). 2009 Jan;62(1):17-26. doi: 10.1038/ja.2008.4. Epub 2009 Jan 9. Review.

PMID:
19132059
14.

DNA binding properties of the indolocarbazole antitumor drug NB-506.

Carrasco C, Vezin H, Wilson WD, Ren J, Chaires JB, Bailly C.

Anticancer Drug Des. 2001 Apr-Jun;16(2-3):99-107.

PMID:
11962518
15.

Rebeccamycin analogues as anti-cancer agents.

Prudhomme M.

Eur J Med Chem. 2003 Feb;38(2):123-40. Review.

PMID:
12620658
16.

Synthesis and biological activities of indolocarbazoles bearing amino acid residues.

Moreau P, Sancelme M, Bailly C, Léonce S, Pierré A, Hickman J, Pfeiffer B, Prudhomme M.

Eur J Med Chem. 2001 Nov-Dec;36(11-12):887-97.

PMID:
11755231
17.

Synthetic studies on indolocarbazoles: total synthesis of staurosporine aglycon.

Rajeshwaran GG, Mohanakrishnan AK.

Org Lett. 2011 Mar 18;13(6):1418-21. doi: 10.1021/ol200094b. Epub 2011 Feb 22.

PMID:
21341756
18.
19.

1,7-annulated indolocarbazoles as cyclin-dependent kinase inhibitors.

Al-awar RS, Ray JE, Hecker KA, Huang J, Waid PP, Shih C, Brooks HB, Spencer CD, Watkins SA, Patel BR, Stamm NB, Ogg CA, Schultz RM, Considine EL, Faul MM, Sullivan KA, Kolis SP, Grutsch JL, Joseph S.

Bioorg Med Chem Lett. 2004 Jun 21;14(12):3217-20.

PMID:
15149678

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