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Items: 1 to 20 of 75

1.

Histone deacetylase inhibitors synergizes with catalytic inhibitors of EZH2 to exhibit anti-tumor activity in small cell carcinoma of the ovary, hypercalcemic type.

Wang Y, Chen SY, Colborne S, Lambert G, Shin CY, Dos Santos N, Orlando KA, Lang JD, Hendricks WPD, Bally MB, Karnezis AN, Hass R, Underhill TM, Morin GB, Trent JM, Weissman BE, Huntsman DG.

Mol Cancer Ther. 2018 Sep 19. pii: molcanther.0348.2018. doi: 10.1158/1535-7163.MCT-18-0348. [Epub ahead of print]

PMID:
30232145
2.

HIC1 links retinoic acid signalling to group 3 innate lymphoid cell-dependent regulation of intestinal immunity and homeostasis.

Burrows K, Antignano F, Chenery A, Bramhall M, Korinek V, Underhill TM, Zaph C.

PLoS Pathog. 2018 Feb 22;14(2):e1006869. doi: 10.1371/journal.ppat.1006869. eCollection 2018 Feb.

3.

Death by HDAC Inhibition in Synovial Sarcoma Cells.

Laporte AN, Poulin NM, Barrott JJ, Wang XQ, Lorzadeh A, Vander Werff R, Jones KB, Underhill TM, Nielsen TO.

Mol Cancer Ther. 2017 Dec;16(12):2656-2667. doi: 10.1158/1535-7163.MCT-17-0397. Epub 2017 Sep 6.

PMID:
28878027
4.

Methyltransferase G9A Regulates Osteogenesis via Twist Gene Repression.

Higashihori N, Lehnertz B, Sampaio A, Underhill TM, Rossi F, Richman JM.

J Dent Res. 2017 Sep;96(10):1136-1144. doi: 10.1177/0022034517716438. Epub 2017 Jun 23.

PMID:
28644763
5.

Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex.

Hassan HM, Kolendowski B, Isovic M, Bose K, Dranse HJ, Sampaio AV, Underhill TM, Torchia J.

Cell Rep. 2017 May 23;19(8):1685-1697. doi: 10.1016/j.celrep.2017.05.007.

6.

The transcriptional repressor HIC1 regulates intestinal immune homeostasis.

Burrows K, Antignano F, Bramhall M, Chenery A, Scheer S, Korinek V, Underhill TM, Zaph C.

Mucosal Immunol. 2017 Nov;10(6):1518-1528. doi: 10.1038/mi.2017.17. Epub 2017 Mar 22.

PMID:
28327618
7.

Tumor-homing cytotoxic human induced neural stem cells for cancer therapy.

Bagó JR, Okolie O, Dumitru R, Ewend MG, Parker JS, Werff RV, Underhill TM, Schmid RS, Miller CR, Hingtgen SD.

Sci Transl Med. 2017 Feb 1;9(375). pii: eaah6510. doi: 10.1126/scitranslmed.aah6510.

PMID:
28148846
8.

HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma.

Laporte AN, Barrott JJ, Yao RJ, Poulin NM, Brodin BA, Jones KB, Underhill TM, Nielsen TO.

PLoS One. 2017 Jan 5;12(1):e0169407. doi: 10.1371/journal.pone.0169407. eCollection 2017.

9.

Methods and Strategies for Lineage Tracing of Mesenchymal Progenitor Cells.

Scott RW, Underhill TM.

Methods Mol Biol. 2016;1416:171-203. doi: 10.1007/978-1-4939-3584-0_10.

PMID:
27236672
10.

Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice.

Chow LN, Schreiner P, Ng BY, Lo B, Hughes MR, Scott RW, Gusti V, Lecour S, Simonson E, Manisali I, Barta I, McNagny KM, Crawford J, Webb M, Underhill TM.

PLoS One. 2016 Mar 21;11(3):e0151765. doi: 10.1371/journal.pone.0151765. eCollection 2016.

11.

Retinoid regulation of antiviral innate immunity in hepatocytes.

Cho NE, Bang BR, Gurung P, Li M, Clemens DL, Underhill TM, James LP, Chase JR, Saito T.

Hepatology. 2016 Jun;63(6):1783-95. doi: 10.1002/hep.28380. Epub 2016 Jan 21.

12.

SOX9 modulates the expression of key transcription factors required for heart valve development.

Garside VC, Cullum R, Alder O, Lu DY, Vander Werff R, Bilenky M, Zhao Y, Jones SJ, Marra MA, Underhill TM, Hoodless PA.

Development. 2015 Dec 15;142(24):4340-50. doi: 10.1242/dev.125252. Epub 2015 Nov 2.

13.

Two novel disease-causing variants in BMPR1B are associated with brachydactyly type A1.

Racacho L, Byrnes AM, MacDonald H, Dranse HJ, Nikkel SM, Allanson J, Rosser E, Underhill TM, Bulman DE.

Eur J Hum Genet. 2015 Dec;23(12):1640-5. doi: 10.1038/ejhg.2015.38. Epub 2015 Mar 11.

14.

The methyltransferase G9a regulates HoxA9-dependent transcription in AML.

Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, Rosten P, Underhill TM, Jin J, Hébert J, Sauvageau G, Humphries RK, Rossi FM.

Genes Dev. 2014 Feb 15;28(4):317-27. doi: 10.1101/gad.236794.113.

15.

Analysis of chondrogenesis using micromass cultures of limb mesenchyme.

Underhill TM, Dranse HJ, Hoffman LM.

Methods Mol Biol. 2014;1130:251-265. doi: 10.1007/978-1-62703-989-5_19.

PMID:
24482179
16.

The retinoic acid-metabolizing enzyme Cyp26b1 regulates CD4 T cell differentiation and function.

Chenery A, Burrows K, Antignano F, Underhill TM, Petkovich M, Zaph C.

PLoS One. 2013 Aug 22;8(8):e72308. doi: 10.1371/journal.pone.0072308. eCollection 2013.

17.

SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas.

Jones KB, Su L, Jin H, Lenz C, Randall RL, Underhill TM, Nielsen TO, Sharma S, Capecchi MR.

Oncogene. 2013 May 2;32(18):2365-71, 2375.e1-5. doi: 10.1038/onc.2012.247. Epub 2012 Jul 16.

18.

Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics.

Su L, Sampaio AV, Jones KB, Pacheco M, Goytain A, Lin S, Poulin N, Yi L, Rossi FM, Kast J, Capecchi MR, Underhill TM, Nielsen TO.

Cancer Cell. 2012 Mar 20;21(3):333-47. doi: 10.1016/j.ccr.2012.01.010.

19.

Functionally convergent white adipogenic progenitors of different lineages participate in a diffused system supporting tissue regeneration.

Lemos DR, Paylor B, Chang C, Sampaio A, Underhill TM, Rossi FM.

Stem Cells. 2012 Jun;30(6):1152-62. doi: 10.1002/stem.1082.

20.

Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes.

Bond SR, Lau A, Penuela S, Sampaio AV, Underhill TM, Laird DW, Naus CC.

J Bone Miner Res. 2011 Dec;26(12):2911-22. doi: 10.1002/jbmr.509.

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