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Items: 1 to 20 of 198

1.

Understanding How Wnt Influences Destruction Complex Activity and β-Catenin Dynamics.

Mukherjee A, Dhar N, Stathos M, Schaffer DV, Kane RS.

iScience. 2018 Aug 31;6:13-21. doi: 10.1016/j.isci.2018.07.007. Epub 2018 Jul 17.

2.

High-throughput identification of factors promoting neuronal differentiation of human neural progenitor cells in microscale 3D cell culture.

Nierode GJ, Gopal S, Kwon P, Clark DS, Schaffer DV, Dordick JS.

Biotechnol Bioeng. 2019 Jan;116(1):168-180. doi: 10.1002/bit.26839. Epub 2018 Oct 27.

PMID:
30229860
3.

Corrigendum to "Engineered viral vectors for functional interrogation, deconvolution, and manipulation of neural circuits" [Curr. Opin. Neurobiol. 50 (2018) 163-170].

Sun S, Schaffer DV.

Curr Opin Neurobiol. 2018 Dec;53:220. doi: 10.1016/j.conb.2018.08.005. Epub 2018 Sep 5. No abstract available.

PMID:
30196036
4.

High-throughput combinatorial screening reveals interactions between signaling molecules that regulate adult neural stem cell fate.

Muckom R, McFarland S, Yang C, Perea B, Gentes M, Murugappan A, Tran E, Dordick JS, Clark DS, Schaffer DV.

Biotechnol Bioeng. 2019 Jan;116(1):193-205. doi: 10.1002/bit.26815. Epub 2018 Nov 6.

PMID:
30102775
5.

The Spectrin-Actin-Based Periodic Cytoskeleton as a Conserved Nanoscale Scaffold and Ruler of the Neural Stem Cell Lineage.

Hauser M, Yan R, Li W, Repina NA, Schaffer DV, Xu K.

Cell Rep. 2018 Aug 7;24(6):1512-1522. doi: 10.1016/j.celrep.2018.07.005.

6.

Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation.

Dong M, Spelke DP, Lee YK, Chung JK, Yu CH, Schaffer DV, Groves JT.

Biophys J. 2018 Sep 4;115(5):865-873. doi: 10.1016/j.bpj.2018.06.031. Epub 2018 Jul 23.

7.

CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window.

Halperin SO, Tou CJ, Wong EB, Modavi C, Schaffer DV, Dueber JE.

Nature. 2018 Aug;560(7717):248-252. doi: 10.1038/s41586-018-0384-8. Epub 2018 Aug 1.

PMID:
30069054
8.

Proliferation versus Differentiation: Redefining Retinoic Acid's Role.

Mosher KI, Schaffer DV.

Stem Cell Reports. 2018 Jun 5;10(6):1673-1675. doi: 10.1016/j.stemcr.2018.05.011.

9.

Thermoreversible Hyaluronic Acid-PNIPAAm Hydrogel Systems for 3D Stem Cell Culture.

Ekerdt BL, Fuentes CM, Lei Y, Adil MM, Ramasubramanian A, Segalman RA, Schaffer DV.

Adv Healthc Mater. 2018 Jun;7(12):e1800225. doi: 10.1002/adhm.201800225. Epub 2018 May 2.

PMID:
29717823
10.

hPSC-Derived Striatal Cells Generated Using a Scalable 3D Hydrogel Promote Recovery in a Huntington Disease Mouse Model.

Adil MM, Gaj T, Rao AT, Kulkarni RU, Fuentes CM, Ramadoss GN, Ekman FK, Miller EW, Schaffer DV.

Stem Cell Reports. 2018 May 8;10(5):1481-1491. doi: 10.1016/j.stemcr.2018.03.007. Epub 2018 Apr 5.

11.

Engineered viral vectors for functional interrogation, deconvolution, and manipulation of neural circuits.

Sun S, Schaffer DV.

Curr Opin Neurobiol. 2018 Jun;50:163-170. doi: 10.1016/j.conb.2017.12.011. Epub 2018 Mar 31. Review. Erratum in: Curr Opin Neurobiol. 2018 Sep 5;:.

PMID:
29614429
12.

hPSC-derived Midbrain Dopaminergic Neurons Generated in a Scalable 3-D Biomaterial.

Adil MM, Schaffer DV.

Curr Protoc Stem Cell Biol. 2018 Feb 28;44:2D.21.1-2D.21.17. doi: 10.1002/cpsc.47.

PMID:
29512105
13.

A Hypothalamic Switch for REM and Non-REM Sleep.

Chen KS, Xu M, Zhang Z, Chang WC, Gaj T, Schaffer DV, Dan Y.

Neuron. 2018 Mar 7;97(5):1168-1176.e4. doi: 10.1016/j.neuron.2018.02.005. Epub 2018 Feb 22.

PMID:
29478915
14.

Optogenetic tools for cell biological applications.

Mukherjee A, Repina NA, Schaffer DV, Kane RS.

J Thorac Dis. 2017 Dec;9(12):4867-4870. doi: 10.21037/jtd.2017.11.73. No abstract available.

15.

In vivo genome editing improves motor function and extends survival in a mouse model of ALS.

Gaj T, Ojala DS, Ekman FK, Byrne LC, Limsirichai P, Schaffer DV.

Sci Adv. 2017 Dec 20;3(12):eaar3952. doi: 10.1126/sciadv.aar3952. eCollection 2017 Dec.

16.

Screening for Neutralizing Antibodies Against Natural and Engineered AAV Capsids in Nonhuman Primate Retinas.

Day TP, Byrne LC, Flannery JG, Schaffer DV.

Methods Mol Biol. 2018;1715:239-249. doi: 10.1007/978-1-4939-7522-8_17.

PMID:
29188518
17.

Matrix degradation: Making way for neural stemness.

Kang PH, Kumar S, Schaffer DV.

Nat Mater. 2017 Nov 24;16(12):1174-1176. doi: 10.1038/nmat5043. No abstract available.

PMID:
29170553
18.

Combining Engineered Nucleases with Adeno-associated Viral Vectors for Therapeutic Gene Editing.

Epstein BE, Schaffer DV.

Adv Exp Med Biol. 2017;1016:29-42. doi: 10.1007/978-3-319-63904-8_2. Review.

19.

Influence of hippocampal niche signals on neural stem cell functions during aging.

Mosher KI, Schaffer DV.

Cell Tissue Res. 2018 Jan;371(1):115-124. doi: 10.1007/s00441-017-2709-6. Epub 2017 Nov 10. Review.

20.

In Vivo Selection of a Computationally Designed SCHEMA AAV Library Yields a Novel Variant for Infection of Adult Neural Stem Cells in the SVZ.

Ojala DS, Sun S, Santiago-Ortiz JL, Shapiro MG, Romero PA, Schaffer DV.

Mol Ther. 2018 Jan 3;26(1):304-319. doi: 10.1016/j.ymthe.2017.09.006. Epub 2017 Sep 8.

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