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Semaphorin 3A potentiates the profibrotic effects of transforming growth factor-β1 in the cornea.

Jeon KI, Nehrke K, Huxlin KR.

Biochem Biophys Res Commun. 2019 Oct 24. pii: S0006-291X(19)32009-1. doi: 10.1016/j.bbrc.2019.10.107. [Epub ahead of print]


Cardioprotection by the mitochondrial unfolded protein response requires ATF5.

Wang YT, Lim Y, McCall MN, Huang KT, Haynes CM, Nehrke K, Brookes PS.

Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H472-H478. doi: 10.1152/ajpheart.00244.2019. Epub 2019 Jul 5.


Fndc-1 contributes to paternal mitochondria elimination in C. elegans.

Lim Y, Rubio-Peña K, Sobraske PJ, Molina PA, Brookes PS, Galy V, Nehrke K.

Dev Biol. 2019 Oct 1;454(1):15-20. doi: 10.1016/j.ydbio.2019.06.016. Epub 2019 Jun 21.


Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH.

Nadtochiy SM, Wang YT, Nehrke K, Munger J, Brookes PS.

J Mol Cell Cardiol. 2018 Aug;121:155-162. doi: 10.1016/j.yjmcc.2018.06.007. Epub 2018 Jun 26.


Cardiac metabolic effects of KNa1.2 channel deletion and evidence for its mitochondrial localization.

Smith CO, Wang YT, Nadtochiy SM, Miller JH, Jonas EA, Dirksen RT, Nehrke K, Brookes PS.

FASEB J. 2018 Jun 4:fj201800139R. doi: 10.1096/fj.201800139R. [Epub ahead of print]


Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation.

Nadtochiy SM, Wang YT, Zhang J, Nehrke K, Schafer X, Welle K, Ghaemmaghami S, Munger J, Brookes PS.

Biochem J. 2017 Aug 10;474(16):2829-2839. doi: 10.1042/BCJ20170389.


The Slo(w) path to identifying the mitochondrial channels responsible for ischemic protection.

Smith CO, Nehrke K, Brookes PS.

Biochem J. 2017 Jun 9;474(12):2067-2094. doi: 10.1042/BCJ20160623. Review.


Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling.

Nadtochiy SM, Schafer X, Fu D, Nehrke K, Munger J, Brookes PS.

J Biol Chem. 2016 Sep 16;291(38):20188-97. doi: 10.1074/jbc.M116.738799. Epub 2016 Aug 10.


The Mitochondrial Unfolded Protein Response Protects against Anoxia in Caenorhabditis elegans.

Peña S, Sherman T, Brookes PS, Nehrke K.

PLoS One. 2016 Jul 26;11(7):e0159989. doi: 10.1371/journal.pone.0159989. eCollection 2016.


Chromophore-Assisted Light Inactivation of Mitochondrial Electron Transport Chain Complex II in Caenorhabditis elegans.

Wojtovich AP, Wei AY, Sherman TA, Foster TH, Nehrke K.

Sci Rep. 2016 Jul 21;6:29695. doi: 10.1038/srep29695.


Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning.

Wojtovich AP, Smith CO, Urciuoli WR, Wang YT, Xia XM, Brookes PS, Nehrke K.

Anesthesiology. 2016 May;124(5):1065-76. doi: 10.1097/ALN.0000000000001046.


A C. elegans model of electronic cigarette use: Physiological effects of e-liquids in nematodes.

Panitz D, Swamy H, Nehrke K.

BMC Pharmacol Toxicol. 2015 Dec 4;16:32. doi: 10.1186/s40360-015-0030-0.


Calcineurin homologous proteins regulate the membrane localization and activity of sodium/proton exchangers in C. elegans.

Allman E, Wang Q, Walker RL, Austen M, Peters MA, Nehrke K.

Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C233-42. doi: 10.1152/ajpcell.00291.2015. Epub 2015 Nov 11.


Membrane ion transport in non-excitable tissues.

Nehrke K.

WormBook. 2014 Dec 23:1-22. doi: 10.1895/wormbook.1.174.1. Review.


An anoxia-starvation model for ischemia/reperfusion in C. elegans.

Queliconi BB, Kowaltowski AJ, Nehrke K.

J Vis Exp. 2014 Mar 11;(85). doi: 10.3791/51231.


Expression of the CHOP-inducible carbonic anhydrase CAVI-b is required for BDNF-mediated protection from hypoxia.

Matthews TA, Abel A, Demme C, Sherman T, Pan PW, Halterman MW, Parkkila S, Nehrke K.

Brain Res. 2014 Jan 16;1543:28-37. doi: 10.1016/j.brainres.2013.11.018. Epub 2013 Nov 23.


Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans.

Coburn C, Allman E, Mahanti P, Benedetto A, Cabreiro F, Pincus Z, Matthijssens F, Araiz C, Mandel A, Vlachos M, Edwards SA, Fischer G, Davidson A, Pryor RE, Stevens A, Slack FJ, Tavernarakis N, Braeckman BP, Schroeder FC, Nehrke K, Gems D.

PLoS Biol. 2013 Jul;11(7):e1001613. doi: 10.1371/journal.pbio.1001613. Epub 2013 Jul 23.


A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel.

Wojtovich AP, Nadtochiy SM, Urciuoli WR, Smith CO, Grunnet M, Nehrke K, Brookes PS.

PeerJ. 2013 Mar 5;1:e48. doi: 10.7717/peerj.48. Print 2013.


Kir6.2 is not the mitochondrial KATP channel but is required for cardioprotection by ischemic preconditioning.

Wojtovich AP, Urciuoli WR, Chatterjee S, Fisher AB, Nehrke K, Brookes PS.

Am J Physiol Heart Circ Physiol. 2013 Jun 1;304(11):H1439-45. doi: 10.1152/ajpheart.00972.2012. Epub 2013 Apr 12.

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