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Items: 1 to 20 of 26

1.

Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy.

Comoglio PM, Trusolino L, Boccaccio C.

Nat Rev Cancer. 2018 Jun;18(6):341-358. doi: 10.1038/s41568-018-0002-y. Review.

PMID:
29674709
2.

A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem-Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy.

Luraghi P, Bigatto V, Cipriano E, Reato G, Orzan F, Sassi F, De Bacco F, Isella C, Bellomo SE, Medico E, Comoglio PM, Bertotti A, Trusolino L, Boccaccio C.

Clin Cancer Res. 2018 Feb 15;24(4):807-820. doi: 10.1158/1078-0432.CCR-17-2151. Epub 2017 Oct 3.

PMID:
28974546
3.

Genetic Evolution of Glioblastoma Stem-Like Cells From Primary to Recurrent Tumor.

Orzan F, De Bacco F, Crisafulli G, Pellegatta S, Mussolin B, Siravegna G, D'Ambrosio A, Comoglio PM, Finocchiaro G, Boccaccio C.

Stem Cells. 2017 Nov;35(11):2218-2228. doi: 10.1002/stem.2703. Epub 2017 Sep 29.

PMID:
28895245
4.

Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.

Isella C, Brundu F, Bellomo SE, Galimi F, Zanella E, Porporato R, Petti C, Fiori A, Orzan F, Senetta R, Boccaccio C, Ficarra E, Marchionni L, Trusolino L, Medico E, Bertotti A.

Nat Commun. 2017 May 31;8:15107. doi: 10.1038/ncomms15107.

5.

MET inhibition overcomes radiation resistance of glioblastoma stem-like cells.

De Bacco F, D'Ambrosio A, Casanova E, Orzan F, Neggia R, Albano R, Verginelli F, Cominelli M, Poliani PL, Luraghi P, Reato G, Pellegatta S, Finocchiaro G, Perera T, Garibaldi E, Gabriele P, Comoglio PM, Boccaccio C.

EMBO Mol Med. 2016 May 2;8(5):550-68. doi: 10.15252/emmm.201505890. Print 2016 May.

6.

TNF-α promotes invasive growth through the MET signaling pathway.

Bigatto V, De Bacco F, Casanova E, Reato G, Lanzetti L, Isella C, Sarotto I, Comoglio PM, Boccaccio C.

Mol Oncol. 2015 Feb;9(2):377-88. doi: 10.1016/j.molonc.2014.09.002. Epub 2014 Sep 26.

7.

MET, a driver of invasive growth and cancer clonal evolution under therapeutic pressure.

Boccaccio C, Comoglio PM.

Curr Opin Cell Biol. 2014 Dec;31:98-105. doi: 10.1016/j.ceb.2014.09.008. Epub 2014 Oct 8. Review.

PMID:
25305631
8.

MET-mediated resistance to EGFR inhibitors: an old liaison rooted in colorectal cancer stem cells.

Boccaccio C, Luraghi P, Comoglio PM.

Cancer Res. 2014 Jul 15;74(14):3647-51. doi: 10.1158/0008-5472.CAN-14-1088. Epub 2014 Jul 1. Review.

9.

MET signaling in colon cancer stem-like cells blunts the therapeutic response to EGFR inhibitors.

Luraghi P, Reato G, Cipriano E, Sassi F, Orzan F, Bigatto V, De Bacco F, Menietti E, Han M, Rideout WM 3rd, Perera T, Bertotti A, Trusolino L, Comoglio PM, Boccaccio C.

Cancer Res. 2014 Mar 15;74(6):1857-69. doi: 10.1158/0008-5472.CAN-13-2340-T. Epub 2014 Jan 21.

10.

The MET oncogene in glioblastoma stem cells: implications as a diagnostic marker and a therapeutic target.

Boccaccio C, Comoglio PM.

Cancer Res. 2013 Jun 1;73(11):3193-9. doi: 10.1158/0008-5472.CAN-12-4039. Epub 2013 May 21. Review.

11.

The MET Oncogene as a Therapeutical Target in Cancer Invasive Growth.

Luraghi P, Schelter F, Krüger A, Boccaccio C.

Front Pharmacol. 2012 Sep 11;3:164. doi: 10.3389/fphar.2012.00164. eCollection 2012.

12.

The MET oncogene is a functional marker of a glioblastoma stem cell subtype.

De Bacco F, Casanova E, Medico E, Pellegatta S, Orzan F, Albano R, Luraghi P, Reato G, D'Ambrosio A, Porrati P, Patanè M, Maderna E, Pollo B, Comoglio PM, Finocchiaro G, Boccaccio C.

Cancer Res. 2012 Sep 1;72(17):4537-50. doi: 10.1158/0008-5472.CAN-11-3490. Epub 2012 Jun 26.

13.

Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.

Gastaldi S, Sassi F, Accornero P, Torti D, Galimi F, Migliardi G, Molyneux G, Perera T, Comoglio PM, Boccaccio C, Smalley MJ, Bertotti A, Trusolino L.

Oncogene. 2013 Mar 14;32(11):1428-40. doi: 10.1038/onc.2012.154. Epub 2012 May 7.

14.

Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer.

De Bacco F, Luraghi P, Medico E, Reato G, Girolami F, Perera T, Gabriele P, Comoglio PM, Boccaccio C.

J Natl Cancer Inst. 2011 Apr 20;103(8):645-61. doi: 10.1093/jnci/djr093. Epub 2011 Apr 4.

15.

Genetic link between cancer and thrombosis.

Boccaccio C, Comoglio PM.

J Clin Oncol. 2009 Oct 10;27(29):4827-33. doi: 10.1200/JCO.2009.22.7199. Epub 2009 Sep 8. Review.

PMID:
19738115
16.

Invasive growth: a MET-driven genetic programme for cancer and stem cells.

Boccaccio C, Comoglio PM.

Nat Rev Cancer. 2006 Aug;6(8):637-45. Review.

PMID:
16862193
17.

Cancer and blood coagulation.

Boccaccio C, Medico E.

Cell Mol Life Sci. 2006 May;63(9):1024-7. Review.

PMID:
16612563
18.

The MET oncogene drives a genetic programme linking cancer to haemostasis.

Boccaccio C, Sabatino G, Medico E, Girolami F, Follenzi A, Reato G, Sottile A, Naldini L, Comoglio PM.

Nature. 2005 Mar 17;434(7031):396-400.

19.

Interactions between growth factor receptors and adhesion molecules: breaking the rules.

Comoglio PM, Boccaccio C, Trusolino L.

Curr Opin Cell Biol. 2003 Oct;15(5):565-71. Review.

PMID:
14519391
20.

Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors.

Follenzi A, Sabatino G, Lombardo A, Boccaccio C, Naldini L.

Hum Gene Ther. 2002 Jan 20;13(2):243-60.

PMID:
11812281

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