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Items: 1 to 20 of 73

1.

NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS.

Ouali Alami N, Schurr C, Olde Heuvel F, Tang L, Li Q, Tasdogan A, Kimbara A, Nettekoven M, Ottaviani G, Raposo C, Röver S, Rogers-Evans M, Rothenhäusler B, Ullmer C, Fingerle J, Grether U, Knuesel I, Boeckers TM, Ludolph A, Wirth T, Roselli F, Baumann B.

EMBO J. 2018 Aug 15;37(16). pii: e98697. doi: 10.15252/embj.201798697. Epub 2018 Jun 6.

2.

High-Grade Osteosarcoma of the Foot: Presentation, Treatment, Prognostic Factors, and Outcome of 23 Cooperative Osteosarcoma Study Group COSS Patients.

Schuster AJ, Kager L, Reichardt P, Baumhoer D, Csóka M, Hecker-Nolting S, Lang S, Lorenzen S, Mayer-Steinacker R, von Kalle T, Kevric M, Werner M, Windhager R, Wirth T, Bielack SS.

Sarcoma. 2018 May 2;2018:1632978. doi: 10.1155/2018/1632978. eCollection 2018.

3.

Tight regulation of FOXO1 is essential for maintenance of B-cell precursor acute lymphoblastic leukemia.

Wang F, Demir S, Gehringer F, Osswald CD, Seyfried F, Enzenmüller S, Eckhoff SM, Maier T, Holzmann K, Debatin KM, Wirth T, Meyer LH, Ushmorov A.

Blood. 2018 Jun 28;131(26):2929-2942. doi: 10.1182/blood-2017-10-813576. Epub 2018 Apr 5.

PMID:
29622548
4.

Fine-tuning of FOXO3A in cHL as a survival mechanism and a hallmark of abortive plasma cell differentiation.

Osswald CD, Xie L, Guan H, Herrmann F, Pick SM, Vogel MJ, Gehringer F, Chan FC, Steidl C, Wirth T, Ushmorov A.

Blood. 2018 Apr 5;131(14):1556-1567. doi: 10.1182/blood-2017-07-795278. Epub 2018 Feb 13.

5.

A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence.

Meyer P, Maity P, Burkovski A, Schwab J, Müssel C, Singh K, Ferreira FF, Krug L, Maier HJ, Wlaschek M, Wirth T, Kestler HA, Scharffetter-Kochanek K.

PLoS Comput Biol. 2017 Dec 4;13(12):e1005741. doi: 10.1371/journal.pcbi.1005741. eCollection 2017 Dec.

6.

IKK2/NF-κB signaling protects neurons after traumatic brain injury.

Mettang M, Reichel SN, Lattke M, Palmer A, Abaei A, Rasche V, Huber-Lang M, Baumann B, Wirth T.

FASEB J. 2018 Apr;32(4):1916-1932. doi: 10.1096/fj.201700826R. Epub 2018 Jan 5.

7.

FOXO in B-cell lymphopoiesis and B cell neoplasia.

Ushmorov A, Wirth T.

Semin Cancer Biol. 2018 Jun;50:132-141. doi: 10.1016/j.semcancer.2017.07.008. Epub 2017 Jul 31. Review.

PMID:
28774833
8.

Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration.

Lattke M, Reichel SN, Magnutzki A, Abaei A, Rasche V, Walther P, Calado DP, Ferger B, Wirth T, Baumann B.

Mol Neurodegener. 2017 Feb 13;12(1):16. doi: 10.1186/s13024-017-0157-0.

9.

Activation of oncogenic pathways in classical Hodgkin lymphoma by decitabine: A rationale for combination with small molecular weight inhibitors.

Swerev TM, Wirth T, Ushmorov A.

Int J Oncol. 2017 Feb;50(2):555-566. doi: 10.3892/ijo.2016.3827. Epub 2016 Dec 30.

PMID:
28035374
10.

Epithelial NEMO/IKKγ limits fibrosis and promotes regeneration during pancreatitis.

Chan LK, Gerstenlauer M, Konukiewitz B, Steiger K, Weichert W, Wirth T, Maier HJ.

Gut. 2017 Nov;66(11):1995-2007. doi: 10.1136/gutjnl-2015-311028. Epub 2016 Jul 27.

PMID:
27464707
11.

Repression of TCF3/E2A contributes to Hodgkin lymphomagenesis.

Guan H, Xie L, Wirth T, Ushmorov A.

Oncotarget. 2016 Jun 14;7(24):36854-36864. doi: 10.18632/oncotarget.9210.

12.

Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response.

Sunami Y, Ringelhan M, Kokai E, Lu M, O'Connor T, Lorentzen A, Weber A, Rodewald AK, Müllhaupt B, Terracciano L, Gul S, Wissel S, Leithäuser F, Krappmann D, Riedl P, Hartmann D, Schirmbeck R, Strnad P, Hüser N, Kleeff J, Friess H, Schmid RM, Geisler F, Wirth T, Heikenwalder M.

Hepatology. 2016 May;63(5):1592-607. doi: 10.1002/hep.28435. Epub 2016 Mar 4.

13.

Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality.

Kraut B, Maier HJ, Kókai E, Fiedler K, Boettger T, Illing A, Kostin S, Walther P, Braun T, Wirth T.

PLoS One. 2015 Nov 5;10(11):e0141591. doi: 10.1371/journal.pone.0141591. eCollection 2015.

14.

NF-κB-dependent signals control BOB.1/OBF.1 and Oct2 transcriptional activity in B cells.

Kilzheimer M, Quandt J, Langhans J, Weihrich P, Wirth T, Brunner C.

Eur J Immunol. 2015 Dec;45(12):3441-53. doi: 10.1002/eji.201545475. Epub 2015 Oct 20.

15.

The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).

von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA.

PLoS One. 2015 Jun 8;10(6):e0129047. doi: 10.1371/journal.pone.0129047. eCollection 2015.

16.

Neuronal redox imbalance results in altered energy homeostasis and early postnatal lethality.

Maity-Kumar G, Thal DR, Baumann B, Scharffetter-Kochanek K, Wirth T.

FASEB J. 2015 Jul;29(7):2843-58. doi: 10.1096/fj.14-265157. Epub 2015 Mar 31.

PMID:
25829510
17.

Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins.

Sauter D, Hotter D, Van Driessche B, Stürzel CM, Kluge SF, Wildum S, Yu H, Baumann B, Wirth T, Plantier JC, Leoz M, Hahn BH, Van Lint C, Kirchhoff F.

Cell Rep. 2015 Feb 3;10(4):586-99. doi: 10.1016/j.celrep.2014.12.047. Epub 2015 Jan 22.

18.

FOXO1 repression contributes to block of plasma cell differentiation in classical Hodgkin lymphoma.

Vogel MJ, Xie L, Guan H, Tooze RM, Maier T, Kostezka U, Maier HJ, Holzmann K, Chan FC, Steidl C, Reichel JB, Weitzer CD, Gehringer F, Kick AB, Cesarman E, Roshal M, Gascoyne RD, Möller P, Wirth T, Ushmorov A.

Blood. 2014 Nov 13;124(20):3118-29. doi: 10.1182/blood-2014-07-590570. Epub 2014 Sep 17.

19.

FOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma.

Xie L, Ritz O, Leithäuser F, Guan H, Färbinger J, Weitzer CD, Gehringer F, Bruederlein S, Holzmann K, Vogel MJ, Möller P, Wirth T, Ushmorov A.

Oncotarget. 2014 Jul 30;5(14):5392-402.

20.

Deficiency of innate and acquired immunity caused by an IKBKB mutation.

Pannicke U, Baumann B, Fuchs S, Henneke P, Rensing-Ehl A, Rizzi M, Janda A, Hese K, Schlesier M, Holzmann K, Borte S, Laux C, Rump EM, Rosenberg A, Zelinski T, Schrezenmeier H, Wirth T, Ehl S, Schroeder ML, Schwarz K.

N Engl J Med. 2013 Dec 26;369(26):2504-14. doi: 10.1056/NEJMoa1309199.

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