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Items: 1 to 20 of 165


CRISPR-Cas9D10A nickase-assisted base editing in solvent producer Clostridium beijerinckii.

Li Q, Seys FM, Minton NP, Yang J, Jiang Y, Jiang W, Yang S.

Biotechnol Bioeng. 2019 Feb 10. doi: 10.1002/bit.26949. [Epub ahead of print]


Regulation of lactate metabolism in the acetogenic bacterium Acetobacterium woodii.

Schoelmerich MC, Katsyv A, Sung W, Mijic V, Wiechmann A, Kottenhahn P, Baker J, Minton NP, Müller V.

Environ Microbiol. 2018 Dec;20(12):4587-4595. doi: 10.1111/1462-2920.14412. Epub 2018 Oct 24.


The Rnf complex is an energy coupled transhydrogenase essential to reversibly link cellular NADH and ferredoxin pools in the acetogen Acetobacterium woodii.

Westphal L, Wiechmann A, Baker J, Minton NP, Müller V.

J Bacteriol. 2018 Aug 20. pii: JB.00357-18. doi: 10.1128/JB.00357-18. [Epub ahead of print]


Functional Genetic Elements for Controlling Gene Expression in Cupriavidus necator H16.

Alagesan S, Hanko EKR, Malys N, Ehsaan M, Winzer K, Minton NP.

Appl Environ Microbiol. 2018 Sep 17;84(19). pii: e00878-18. doi: 10.1128/AEM.00878-18. Print 2018 Oct 1.


Effect of antibiotic treatment on the formation of non-spore Clostridium difficile persister-like cells.

Álvarez R, Inostroza O, Garavaglia M, Minton NP, Paredes-Sabja D, Gil F.

J Antimicrob Chemother. 2018 Sep 1;73(9):2396-2399. doi: 10.1093/jac/dky186.


Progress towards platform chemical production using Clostridium autoethanogenum.

Norman ROJ, Millat T, Winzer K, Minton NP, Hodgman C.

Biochem Soc Trans. 2018 Jun 19;46(3):523-535. doi: 10.1042/BST20170259. Epub 2018 Apr 17. Review.


The Butanol Producing Microbe Clostridium beijerinckii NCIMB 14988 Manipulated Using Forward and Reverse Genetic Tools.

Little GT, Willson BJ, Heap JT, Winzer K, Minton NP.

Biotechnol J. 2018 Nov;13(11):e1700711. doi: 10.1002/biot.201700711. Epub 2018 Apr 29.


A Transcription Factor-Based Biosensor for Detection of Itaconic Acid.

Hanko EKR, Minton NP, Malys N.

ACS Synth Biol. 2018 May 18;7(5):1436-1446. doi: 10.1021/acssynbio.8b00057. Epub 2018 Apr 17.


Quantitative Isotope-Dilution High-Resolution-Mass-Spectrometry Analysis of Multiple Intracellular Metabolites in Clostridium autoethanogenum with Uniformly 13C-Labeled Standards Derived from Spirulina.

Schatschneider S, Abdelrazig S, Safo L, Henstra AM, Millat T, Kim DH, Winzer K, Minton NP, Barrett DA.

Anal Chem. 2018 Apr 3;90(7):4470-4477. doi: 10.1021/acs.analchem.7b04758. Epub 2018 Mar 21.


Advances in metabolic engineering in the microbial production of fuels and chemicals from C1 gas.

Humphreys CM, Minton NP.

Curr Opin Biotechnol. 2018 Apr;50:174-181. doi: 10.1016/j.copbio.2017.12.023. Epub 2018 Feb 3. Review.


Characterization of the impact of rpoB mutations on the in vitro and in vivo competitive fitness of Clostridium difficile and susceptibility to fidaxomicin.

Kuehne SA, Dempster AW, Collery MM, Joshi N, Jowett J, Kelly ML, Cave R, Longshaw CM, Minton NP.

J Antimicrob Chemother. 2018 Apr 1;73(4):973-980. doi: 10.1093/jac/dkx486.


13C-assisted metabolic flux analysis to investigate heterotrophic and mixotrophic metabolism in Cupriavidus necator H16.

Alagesan S, Minton NP, Malys N.

Metabolomics. 2018;14(1):9. doi: 10.1007/s11306-017-1302-z. Epub 2017 Dec 4.


Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability.

Jain S, Smyth D, O'Hagan BMG, Heap JT, McMullan G, Minton NP, Ternan NG.

Sci Rep. 2017 Dec 13;7(1):17522. doi: 10.1038/s41598-017-17583-9.


Applying asymptotic methods to synthetic biology: Modelling the reaction kinetics of the mevalonate pathway.

Dalwadi MP, Garavaglia M, Webb JP, King JR, Minton NP.

J Theor Biol. 2018 Feb 14;439:39-49. doi: 10.1016/j.jtbi.2017.11.022. Epub 2017 Dec 2.


Multi-timescale analysis of a metabolic network in synthetic biology: a kinetic model for 3-hydroxypropionic acid production via beta-alanine.

Dalwadi MP, King JR, Minton NP.

J Math Biol. 2018 Jul;77(1):165-199. doi: 10.1007/s00285-017-1189-3. Epub 2017 Nov 20.


Improving gene transfer in Clostridium pasteurianum through the isolation of rare hypertransformable variants.

Grosse-Honebrink A, Schwarz KM, Wang H, Minton NP, Zhang Y.

Anaerobe. 2017 Dec;48:203-205. doi: 10.1016/j.anaerobe.2017.09.001. Epub 2017 Sep 9.


Syngas Biorefinery and Syngas Utilization.

De Tissera S, Köpke M, Simpson SD, Humphreys C, Minton NP, Dürre P.

Adv Biochem Eng Biotechnol. 2019;166:247-280. doi: 10.1007/10_2017_5.


Microbial solvent formation revisited by comparative genome analysis.

Poehlein A, Solano JDM, Flitsch SK, Krabben P, Winzer K, Reid SJ, Jones DT, Green E, Minton NP, Daniel R, Dürre P.

Biotechnol Biofuels. 2017 Mar 9;10:58. doi: 10.1186/s13068-017-0742-z. eCollection 2017.


Towards improved butanol production through targeted genetic modification of Clostridium pasteurianum.

Schwarz KM, Grosse-Honebrink A, Derecka K, Rotta C, Zhang Y, Minton NP.

Metab Eng. 2017 Mar;40:124-137. doi: 10.1016/j.ymben.2017.01.009. Epub 2017 Jan 22.

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