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Items: 8


The Type B Flagellin of Hypervirulent Clostridium difficile Is Modified with Novel Sulfonated Peptidylamido-glycans.

Bouché L, Panico M, Hitchen P, Binet D, Sastre F, Faulds-Pain A, Valiente E, Vinogradov E, Aubry A, Fulton K, Twine S, Logan SM, Wren BW, Dell A, Morris HR.

J Biol Chem. 2016 Dec 2;291(49):25439-25449. Epub 2016 Oct 7.


Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation.

Valiente E, Bouché L, Hitchen P, Faulds-Pain A, Songane M, Dawson LF, Donahue E, Stabler RA, Panico M, Morris HR, Bajaj-Elliott M, Logan SM, Dell A, Wren BW.

J Biol Chem. 2016 Dec 2;291(49):25450-25461. Epub 2016 Oct 4.


The post-translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence.

Faulds-Pain A, Twine SM, Vinogradov E, Strong PC, Dell A, Buckley AM, Douce GR, Valiente E, Logan SM, Wren BW.

Mol Microbiol. 2014 Oct;94(2):272-89. doi: 10.1111/mmi.12755. Epub 2014 Sep 15.


The agr locus regulates virulence and colonization genes in Clostridium difficile 027.

Martin MJ, Clare S, Goulding D, Faulds-Pain A, Barquist L, Browne HP, Pettit L, Dougan G, Lawley TD, Wren BW.

J Bacteriol. 2013 Aug;195(16):3672-81. doi: 10.1128/JB.00473-13. Epub 2013 Jun 14.


Improved bacterial mutagenesis by high-frequency allele exchange, demonstrated in Clostridium difficile and Streptococcus suis.

Faulds-Pain A, Wren BW.

Appl Environ Microbiol. 2013 Aug;79(15):4768-71. doi: 10.1128/AEM.01195-13. Epub 2013 May 31.


Characterisation of Clostridium difficile biofilm formation, a role for Spo0A.

Dawson LF, Valiente E, Faulds-Pain A, Donahue EH, Wren BW.

PLoS One. 2012;7(12):e50527. doi: 10.1371/journal.pone.0050527. Epub 2012 Dec 7.


Structural insight into the Clostridium difficile ethanolamine utilisation microcompartment.

Pitts AC, Tuck LR, Faulds-Pain A, Lewis RJ, Marles-Wright J.

PLoS One. 2012;7(10):e48360. doi: 10.1371/journal.pone.0048360. Epub 2012 Oct 29.


Flagellin redundancy in Caulobacter crescentus and its implications for flagellar filament assembly.

Faulds-Pain A, Birchall C, Aldridge C, Smith WD, Grimaldi G, Nakamura S, Miyata T, Gray J, Li G, Tang JX, Namba K, Minamino T, Aldridge PD.

J Bacteriol. 2011 Jun;193(11):2695-707. doi: 10.1128/JB.01172-10. Epub 2011 Mar 25.

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