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Items: 1 to 20 of 35


Antibiotic Spider Silk: Site-Specific Functionalization of Recombinant Spider Silk Using "Click" Chemistry.

Harvey D, Bardelang P, Goodacre SL, Cockayne A, Thomas NR.

Adv Mater. 2017 Mar;29(10). doi: 10.1002/adma.201604245. Epub 2016 Dec 28.


What's a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives.

Collery MM, Kuehne SA, McBride SM, Kelly ML, Monot M, Cockayne A, Dupuy B, Minton NP.

Virulence. 2017 Aug 18;8(6):767-781. doi: 10.1080/21505594.2016.1237333. Epub 2016 Sep 21.


Improving the reproducibility of the NAP1/B1/027 epidemic strain R20291 in the hamster model of infection.

Kelly ML, Ng YK, Cartman ST, Collery MM, Cockayne A, Minton NP.

Anaerobe. 2016 Jun;39:51-3. doi: 10.1016/j.anaerobe.2016.02.011. Epub 2016 Mar 2.


Development of a heptaplex PCR assay for identification of Staphylococcus aureus and CoNS with simultaneous detection of virulence and antibiotic resistance genes.

Okolie CE, Wooldridge KG, Turner DP, Cockayne A, James R.

BMC Microbiol. 2015 Aug 5;15:157. doi: 10.1186/s12866-015-0490-9.


Pathogenesis of Clostridium difficile Infection and Its Potential Role in Inflammatory Bowel Disease.

Monaghan TM, Cockayne A, Mahida YR.

Inflamm Bowel Dis. 2015 Aug;21(8):1957-66. doi: 10.1097/MIB.0000000000000461. Review.


Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors.

Murray EJ, Crowley RC, Truman A, Clarke SR, Cottam JA, Jadhav GP, Steele VR, O'Shea P, Lindholm C, Cockayne A, Chhabra SR, Chan WC, Williams P.

J Med Chem. 2014 Mar 27;57(6):2813-9. doi: 10.1021/jm500215s. Epub 2014 Mar 13.


Engineering of the LukS-PV and LukF-PV subunits of Staphylococcus aureus Panton-Valentine leukocidin for diagnostic and therapeutic applications.

Okolie CE, Cockayne A, Penfold C, James R.

BMC Biotechnol. 2013 Nov 19;13:103. doi: 10.1186/1472-6750-13-103.


Importance of toxin A, toxin B, and CDT in virulence of an epidemic Clostridium difficile strain.

Kuehne SA, Collery MM, Kelly ML, Cartman ST, Cockayne A, Minton NP.

J Infect Dis. 2014 Jan 1;209(1):83-6. doi: 10.1093/infdis/jit426. Epub 2013 Aug 9.


Combinatorial discovery of polymers resistant to bacterial attachment.

Hook AL, Chang CY, Yang J, Luckett J, Cockayne A, Atkinson S, Mei Y, Bayston R, Irvine DJ, Langer R, Anderson DG, Williams P, Davies MC, Alexander MR.

Nat Biotechnol. 2012 Sep;30(9):868-875. doi: 10.1038/nbt.2316. Erratum in: Nat Biotechnol. 2014 Jun;32(6):592.


The role of toxin A and toxin B in Clostridium difficile infection.

Kuehne SA, Cartman ST, Heap JT, Kelly ML, Cockayne A, Minton NP.

Nature. 2010 Oct 7;467(7316):711-3. doi: 10.1038/nature09397. Epub 2010 Sep 15.


The emergence of 'hypervirulence' in Clostridium difficile.

Cartman ST, Heap JT, Kuehne SA, Cockayne A, Minton NP.

Int J Med Microbiol. 2010 Aug;300(6):387-95. doi: 10.1016/j.ijmm.2010.04.008. Epub 2010 May 23. Review.


Control of bacterial aggregation by thermoresponsive glycopolymers.

Pasparakis G, Cockayne A, Alexander C.

J Am Chem Soc. 2007 Sep 12;129(36):11014-5. Epub 2007 Aug 16. No abstract available.


Crystal structure of the heme-IsdC complex, the central conduit of the Isd iron/heme uptake system in Staphylococcus aureus.

Sharp KH, Schneider S, Cockayne A, Paoli M.

J Biol Chem. 2007 Apr 6;282(14):10625-31. Epub 2007 Feb 7.


N-acylhomoserine lactones antagonize virulence gene expression and quorum sensing in Staphylococcus aureus.

Qazi S, Middleton B, Muharram SH, Cockayne A, Hill P, O'Shea P, Chhabra SR, Cámara M, Williams P.

Infect Immun. 2006 Feb;74(2):910-9.


The staphylococcal ferritins are differentially regulated in response to iron and manganese and via PerR and Fur.

Morrissey JA, Cockayne A, Brummell K, Williams P.

Infect Immun. 2004 Feb;72(2):972-9.


Side-chain-to-tail thiolactone peptide inhibitors of the staphylococcal quorum-sensing system.

Scott RJ, Lian LY, Muharram SH, Cockayne A, Wood SJ, Bycroft BW, Williams P, Chan WC.

Bioorg Med Chem Lett. 2003 Aug 4;13(15):2449-53.


NapA protects Helicobacter pylori from oxidative stress damage, and its production is influenced by the ferric uptake regulator.

Cooksley C, Jenks PJ, Green A, Cockayne A, Logan RP, Hardie KR.

J Med Microbiol. 2003 Jun;52(Pt 6):461-9.


Conservation, surface exposure, and in vivo expression of the Frp family of iron-regulated cell wall proteins in Staphylococcus aureus.

Morrissey JA, Cockayne A, Hammacott J, Bishop K, Denman-Johnson A, Hill PJ, Williams P.

Infect Immun. 2002 May;70(5):2399-407.

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