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Items: 1 to 20 of 99


CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation.

Mishra SK, Gao YG, Deng Y, Chalfant CE, Hinchcliffe EH, Brown RE.

Autophagy. 2018;14(5):862-879. doi: 10.1080/15548627.2017.1393129. Epub 2018 Feb 21.


Neutrophil elastase increases airway ceramide levels via upregulation of serine palmitoyltransferase.

Karandashova S, Kummarapurugu AB, Zheng S, Chalfant CE, Voynow JA.

Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L206-L214. doi: 10.1152/ajplung.00322.2017. Epub 2017 Oct 12.


Splice variants of cytosolic polyadenylation element-binding protein 2 (CPEB2) differentially regulate pathways linked to cancer metastasis.

DeLigio JT, Lin G, Chalfant CE, Park MA.

J Biol Chem. 2017 Oct 27;292(43):17909-17918. doi: 10.1074/jbc.M117.810127. Epub 2017 Sep 13.


Lipidomics in translational research and the clinical significance of lipid-based biomarkers.

Stephenson DJ, Hoeferlin LA, Chalfant CE.

Transl Res. 2017 Nov;189:13-29. doi: 10.1016/j.trsl.2017.06.006. Epub 2017 Jun 15. Review.


Impact of high dose vitamin C on platelet function.

Mohammed BM, Sanford KW, Fisher BJ, Martin EJ, Contaifer D Jr, Warncke UO, Wijesinghe DS, Chalfant CE, Brophy DF, Fowler Iii AA, Natarajan R.

World J Crit Care Med. 2017 Feb 4;6(1):37-47. doi: 10.5492/wjccm.v6.i1.37. eCollection 2017 Feb 4.


Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients.

Qi H, Priyadarsini S, Nicholas SE, Sarker-Nag A, Allegood J, Chalfant CE, Mandal NA, Karamichos D.

J Lipid Res. 2017 Apr;58(4):636-648. doi: 10.1194/jlr.M067264. Epub 2017 Feb 10.


PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X.

Vhuiyan MI, Pak ML, Park MA, Thomas D, Lakowski TM, Chalfant CE, Frankel A.

J Biochem. 2017 Jul 1;162(1):17-25. doi: 10.1093/jb/mvw102.


Unsupervised analysis of combined lipid and coagulation data reveals coagulopathy subtypes among dialysis patients.

Contaifer D Jr, Carl DE, Warncke UO, Martin EJ, Mohammed BM, Van Tassell B, Brophy DF, Chalfant CE, Wijesinghe DS.

J Lipid Res. 2017 Mar;58(3):586-599. doi: 10.1194/jlr.P068833. Epub 2016 Dec 19.


Melanoma Differentiation-associated Gene 7/IL-24 Exerts Cytotoxic Effects by Altering the Alternative Splicing of Bcl-x Pre-mRNA via the SRC/PKCδ Signaling Axis.

Shapiro BA, Vu NT, Shultz MD, Shultz JC, Mietla JA, Gouda MM, Yacoub A, Dent P, Fisher PB, Park MA, Chalfant CE.

J Biol Chem. 2016 Oct 7;291(41):21669-21681. Epub 2016 Aug 12.


Caspase-9b Interacts Directly with cIAP1 to Drive Agonist-Independent Activation of NF-κB and Lung Tumorigenesis.

Vu NT, Park MA, Shultz MD, Bulut GB, Ladd AC, Chalfant CE.

Cancer Res. 2016 May 15;76(10):2977-89. doi: 10.1158/0008-5472.CAN-15-2512. Epub 2016 Mar 29.


Role of integrin α7β1 signaling in myoblast differentiation on aligned polydioxanone scaffolds.

McClure MJ, Clark NM, Hyzy SL, Chalfant CE, Olivares-Navarrete R, Boyan BD, Schwartz Z.

Acta Biomater. 2016 Jul 15;39:44-54. doi: 10.1016/j.actbio.2016.04.046. Epub 2016 Apr 30.


Sphingolipid profile alters in retinal dystrophic P23H-1 rats and systemic FTY720 can delay retinal degeneration.

Stiles M, Qi H, Sun E, Tan J, Porter H, Allegood J, Chalfant CE, Yasumura D, Matthes MT, LaVail MM, Mandal NA.

J Lipid Res. 2016 May;57(5):818-31. doi: 10.1194/jlr.M063719. Epub 2016 Mar 5.


Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects.

Kolawole EM, McLeod JJ, Ndaw V, Abebayehu D, Barnstein BO, Faber T, Spence AJ, Taruselli M, Paranjape A, Haque TT, Qayum AA, Kazmi QA, Wijesinghe DS, Sturgill JL, Chalfant CE, Straus DB, Oskeritzian CA, Ryan JJ.

J Immunol. 2016 Feb 15;196(4):1461-70. doi: 10.4049/jimmunol.1501932. Epub 2016 Jan 15.


Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors.

Katz S, Ernst O, Avni D, Athamna M, Philosoph A, Arana L, Ouro A, Hoeferlin LA, Meijler MM, Chalfant CE, Gómez-Muñoz A, Zor T.

Immunol Lett. 2016 Jan;169:73-81. doi: 10.1016/j.imlet.2015.12.001. Epub 2015 Dec 3.


The Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2 Drives Anoikis Resistance and the Metastasis of Triple Negative Breast Cancer.

Johnson RM, Vu NT, Griffin BP, Gentry AE, Archer KJ, Chalfant CE, Park MA.

J Biol Chem. 2015 Oct 16;290(42):25717-27. doi: 10.1074/jbc.M115.671206. Epub 2015 Aug 24.


Anaplasma phagocytophilum Rab10-dependent parasitism of the trans-Golgi network is critical for completion of the infection cycle.

Truchan HK, VieBrock L, Cockburn CL, Ojogun N, Griffin BP, Wijesinghe DS, Chalfant CE, Carlyon JA.

Cell Microbiol. 2016 Feb;18(2):260-81. doi: 10.1111/cmi.12500. Epub 2015 Oct 7.


Arachidonic acid-derived signaling lipids and functions in impaired healing.

Dhall S, Wijesinghe DS, Karim ZA, Castro A, Vemana HP, Khasawneh FT, Chalfant CE, Martins-Green M.

Wound Repair Regen. 2015 Sep;23(5):644-56. doi: 10.1111/wrr.12337. Epub 2015 Sep 14.


Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension.

Al-Husseini A, Wijesinghe DS, Farkas L, Kraskauskas D, Drake JI, Van Tassel B, Abbate A, Chalfant CE, Voelkel NF.

PLoS One. 2015 Mar 18;10(3):e0120157. doi: 10.1371/journal.pone.0120157. eCollection 2015.


Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells.

Barbour SE, Nguyen PT, Park M, Emani B, Lei X, Kambalapalli M, Shultz JC, Wijesinghe D, Chalfant CE, Ramanadham S.

J Biol Chem. 2015 Apr 24;290(17):11021-31. doi: 10.1074/jbc.M115.648956. Epub 2015 Mar 11.


The Lipid Portion of Activated Platelet-Rich Plasma Significantly Contributes to Its Wound Healing Properties.

Hoeferlin LA, Huynh QK, Mietla JA, Sell SA, Tucker J, Chalfant CE, Wijesinghe DS.

Adv Wound Care (New Rochelle). 2015 Feb 1;4(2):100-109.

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