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Items: 22

1.

Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species.

Jensen L, Helleberg H, Roffel A, van Lier JJ, Bjørnsdottir I, Pedersen PJ, Rowe E, Derving Karsbøl J, Pedersen ML.

Eur J Pharm Sci. 2017 Jun 15;104:31-41. doi: 10.1016/j.ejps.2017.03.020. Epub 2017 Mar 16.

2.

An evaluation of human ADME and mass balance studies using regular or low doses of radiocarbon.

Roffel AF, van Marle SP, van Lier JJ, Hartstra J, van Hoogdalem EJ.

J Labelled Comp Radiopharm. 2016 Dec;59(14):619-626. doi: 10.1002/jlcr.3473. Review.

PMID:
28000265
3.

Metabolism and disposition of the αv-integrin ß3/ß5 receptor antagonist cilengitide, a cyclic polypeptide, in humans.

Becker A, von Richter O, Kovar A, Scheible H, van Lier JJ, Johne A.

J Clin Pharmacol. 2015 Jul;55(7):815-24. doi: 10.1002/jcph.482. Epub 2015 Mar 23.

PMID:
25683324
4.

Lack of effect of lacosamide on the pharmacokinetic and pharmacodynamic profiles of warfarin.

Stockis A, van Lier JJ, Cawello W, Kumke T, Eckhardt K.

Epilepsia. 2013 Jul;54(7):1161-6. doi: 10.1111/epi.12192. Epub 2013 Apr 24.

5.

Absorption, metabolism and excretion of [(14)C]mirabegron (YM178), a potent and selective β(3)-adrenoceptor agonist, after oral administration to healthy male volunteers.

Takusagawa S, van Lier JJ, Suzuki K, Nagata M, Meijer J, Krauwinkel W, Schaddelee M, Sekiguchi M, Miyashita A, Iwatsubo T, van Gelderen M, Usui T.

Drug Metab Dispos. 2012 Apr;40(4):815-24. doi: 10.1124/dmd.111.043588. Epub 2012 Jan 23.

6.

Antiviral activity of narlaprevir combined with ritonavir and pegylated interferon in chronic hepatitis C patients.

de Bruijne J, Bergmann JF, Reesink HW, Weegink CJ, Molenkamp R, Schinkel J, Tong X, Li J, Treitel MA, Hughes EA, van Lier JJ, van Vliet AA, Janssen HL, de Knegt RJ.

Hepatology. 2010 Nov;52(5):1590-9. doi: 10.1002/hep.23899.

PMID:
20938912
7.

Metabolism and excretion of the once-daily human glucagon-like peptide-1 analog liraglutide in healthy male subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase.

Malm-Erjefält M, Bjørnsdottir I, Vanggaard J, Helleberg H, Larsen U, Oosterhuis B, van Lier JJ, Zdravkovic M, Olsen AK.

Drug Metab Dispos. 2010 Nov;38(11):1944-53. doi: 10.1124/dmd.110.034066. Epub 2010 Aug 13.

9.

Lack of effect of amisulpride on the pharmacokinetics and safety of lithium.

Canal M, Legangneux E, van Lier JJ, van Vliet AA, Coulouvrat C.

Int J Neuropsychopharmacol. 2003 Jun;6(2):103-9.

PMID:
12890302
10.

Excretion and metabolism of desogestrel in healthy postmenopausal women.

Verhoeven CH, Gloudemans RH, Peeters PA, van Lier JJ, Verheggen FT, Groothuis GM, Rietjens IM, Vos RM.

J Steroid Biochem Mol Biol. 2001 Nov;78(5):471-80.

PMID:
11738557
11.

Inhibitory effect of telmisartan on the blood pressure response to angiotensin II challenge.

Stangier J, Su CA, van Heiningen PN, Meinicke T, van Lier JJ, de Bruin H, Tamminga WJ, Jonkman JH.

J Cardiovasc Pharmacol. 2001 Nov;38(5):672-85.

PMID:
11602814
12.

Anticoagulant pharmacodynamics of tinzaparin following 175 iu/kg subcutaneous administration to healthy volunteers.

Barrett JS, Hainer JW, Kornhauser DM, Gaskill JL, Hua TA, Sprogel P, Johansen K, van Lier JJ, Knebel W, Pieniaszek HJ Jr.

Thromb Res. 2001 Feb 15;101(4):243-54.

PMID:
11248285
13.

The effect of telmisartan on the steady-state pharmacokinetics of digoxin in healthy male volunteers.

Stangier J, Su CA, Hendriks MG, van Lier JJ, Sollie FA, Oosterhuis B, Jonkman JH.

J Clin Pharmacol. 2000 Dec;40(12 Pt 1):1373-9.

PMID:
11185636
14.

Steady-state pharmacodynamics and pharmacokinetics of warfarin in the presence and absence of telmisartan in healthy male volunteers.

Stangier J, Su CA, Hendriks MG, van Lier JJ, Sollie FA, Oosterhuis B, Jonkman JH.

J Clin Pharmacol. 2000 Dec;40(12 Pt 1):1331-7.

PMID:
11185631
15.

Absorption, metabolism and excretion of a single oral dose of (14)C-repaglinide during repaglinide multiple dosing.

van Heiningen PN, Hatorp V, Kramer Nielsen K, Hansen KT, van Lier JJ, De Merbel NC, Oosterhuis B, Jonkman JH.

Eur J Clin Pharmacol. 1999 Sep;55(7):521-5.

PMID:
10501822
16.

The absolute bioavailability and effect of food on the pharmacokinetics of zolmitriptan in healthy volunteers.

Seaber EJ, Peck RW, Smith DA, Allanson J, Hefting NR, van Lier JJ, Sollie FA, Wemer J, Jonkman JH.

Br J Clin Pharmacol. 1998 Nov;46(5):433-9.

17.

Pharmacokinetics of [14C]-labelled Losigamone and enantiomers after oral administration to healthy subjects.

Peeters PA, Van Lier JJ, Van De Merbel N, Oosterhuis B, Wieling J, Jonkman JH, Klessing K, Biber A.

Eur J Drug Metab Pharmacokinet. 1998 Jan-Mar;23(1):45-53.

PMID:
9625272
18.

Pharmacokinetic drug interaction studies with candesartan cilexetil.

Jonkman JH, van Lier JJ, van Heiningen PN, Lins R, Sennewald R, Högemann A.

J Hum Hypertens. 1997 Sep;11 Suppl 2:S31-5.

PMID:
9331003
19.

Absorption, metabolism and excretion of 14C-candesartan and 14C-candesartan cilexetil in healthy volunteers.

van Lier JJ, van Heiningen PN, Sunzel M.

J Hum Hypertens. 1997 Sep;11 Suppl 2:S27-8. No abstract available.

PMID:
9331001
20.

The cognitive, subjective, and physical effects of a ginkgo biloba/panax ginseng combination in healthy volunteers with neurasthenic complaints.

Wesnes KA, Faleni RA, Hefting NR, Hoogsteen G, Houben JJ, Jenkins E, Jonkman JH, Leonard J, Petrini O, van Lier JJ.

Psychopharmacol Bull. 1997;33(4):677-83.

PMID:
9493479
21.

Doubling time and hCG score for the early diagnosis of ectopic pregnancy in asymptomatic women.

Tinga DJ, van Lier JJ, de Bruijn HW.

Acta Obstet Gynecol Scand. 1990;69(6):505-9.

PMID:
2284900
22.

B-Z transition in methylated DNA. A quantum-chemical study.

Van Lier JJ, Smits MT, Buck HM.

Eur J Biochem. 1983 Apr 15;132(1):55-62.

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