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Items: 15

1.

The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.

Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M.

EMBO Mol Med. 2018 Jan 17. pii: e8047. doi: 10.15252/emmm.201708047. [Epub ahead of print]

2.

Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis.

Hoeke G, Wang Y, van Dam AD, Mol IM, Gart E, Klop HG, van den Berg SM, Pieterman EH, Princen HMG, Groen AK, Rensen PCN, Berbée JFP, Boon MR.

Atherosclerosis. 2017 Dec;267:116-126. doi: 10.1016/j.atherosclerosis.2017.10.030. Epub 2017 Oct 26.

PMID:
29121499
3.

South Asian men have lower expression of IFN signalling genes in white adipose tissue and skeletal muscle compared with white men.

van Dam AD, Hanssen MJW, van Eenige R, Quinten E, Sips HC, Hülsman CJM, Jazet IM, van Marken Lichtenbelt WD, Ottenhoff THM, Haks MC, Rensen PCN, Boon MR.

Diabetologia. 2017 Dec;60(12):2525-2528. doi: 10.1007/s00125-017-4427-8. Epub 2017 Sep 8. No abstract available.

PMID:
28887664
4.

IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.

van Dam AD, van Beek L, Pronk ACM, van den Berg SM, Van den Bossche J, de Winther MPJ, Koning F, van Kooten C, Rensen PCN, Boon MR, Verbeek JS, van Dijk KW, van Harmelen V.

Int J Obes (Lond). 2018 Feb;42(2):260-269. doi: 10.1038/ijo.2017.209. Epub 2017 Aug 30.

PMID:
28852207
5.

Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.

van den Berg SM, van Dam AD, Kusters PJH, Beckers L, den Toom M, van der Velden S, Van den Bossche J, van Die I, Boon MR, Rensen PCN, Lutgens E, de Winther MPJ.

J Mol Endocrinol. 2017 Oct;59(3):245-255. doi: 10.1530/JME-17-0112. Epub 2017 Jul 10.

PMID:
28694301
6.

Targeting white, brown and perivascular adipose tissue in atherosclerosis development.

van Dam AD, Boon MR, Berbée JFP, Rensen PCN, van Harmelen V.

Eur J Pharmacol. 2017 Dec 5;816:82-92. doi: 10.1016/j.ejphar.2017.03.051. Epub 2017 Mar 24.

7.

Immune Modulation of Brown(ing) Adipose Tissue in Obesity.

van den Berg SM, van Dam AD, Rensen PC, de Winther MP, Lutgens E.

Endocr Rev. 2017 Feb 1;38(1):46-68. doi: 10.1210/er.2016-1066. Review.

PMID:
27849358
8.

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MPJ, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PCN, Berbée JFP.

Atherosclerosis. 2016 Aug;251:6-14. doi: 10.1016/j.atherosclerosis.2016.05.031. Epub 2016 May 19.

9.

FcRγ-chain deficiency reduces the development of diet-induced obesity.

van Beek L, Vroegrijk IO, Katiraei S, Heemskerk MM, van Dam AD, Kooijman S, Rensen PC, Koning F, Verbeek JS, Willems van Dijk K, van Harmelen V.

Obesity (Silver Spring). 2015 Dec;23(12):2435-44. doi: 10.1002/oby.21309. Epub 2015 Nov 2.

10.

Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes.

Liang W, Verschuren L, Mulder P, van der Hoorn JW, Verheij J, van Dam AD, Boon MR, Princen HM, Havekes LM, Kleemann R, van den Hoek AM.

Br J Pharmacol. 2015 Nov;172(22):5293-305. doi: 10.1111/bph.13315. Epub 2015 Oct 22.

11.

Regulation of brown fat by AMP-activated protein kinase.

van Dam AD, Kooijman S, Schilperoort M, Rensen PC, Boon MR.

Trends Mol Med. 2015 Sep;21(9):571-9. doi: 10.1016/j.molmed.2015.07.003. Epub 2015 Aug 10. Review.

PMID:
26271143
12.

Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells.

Wang Y, van der Tuin S, Tjeerdema N, van Dam AD, Rensen SS, Hendrikx T, Berbée JF, Atanasovska B, Fu J, Hoekstra M, Bekkering S, Riksen NP, Buurman WA, Greve JW, Hofker MH, Shiri-Sverdlov R, Meijer OC, Smit JW, Havekes LM, van Dijk KW, Rensen PC.

Hepatology. 2015 Dec;62(6):1710-22. doi: 10.1002/hep.27985. Epub 2015 Aug 28.

PMID:
26174697
13.

The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice.

van Beek L, van Klinken JB, Pronk AC, van Dam AD, Dirven E, Rensen PC, Koning F, Willems van Dijk K, van Harmelen V.

Diabetologia. 2015 Jul;58(7):1601-9. doi: 10.1007/s00125-015-3594-8. Epub 2015 May 12.

14.

Salsalate activates brown adipose tissue in mice.

van Dam AD, Nahon KJ, Kooijman S, van den Berg SM, Kanhai AA, Kikuchi T, Heemskerk MM, van Harmelen V, Lombès M, van den Hoek AM, de Winther MP, Lutgens E, Guigas B, Rensen PC, Boon MR.

Diabetes. 2015 May;64(5):1544-54. doi: 10.2337/db14-1125. Epub 2014 Dec 4.

15.

Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity.

Boon MR, Kooijman S, van Dam AD, Pelgrom LR, Berbée JF, Visseren CA, van Aggele RC, van den Hoek AM, Sips HC, Lombès M, Havekes LM, Tamsma JT, Guigas B, Meijer OC, Jukema JW, Rensen PC.

FASEB J. 2014 Dec;28(12):5361-75. doi: 10.1096/fj.13-247643. Epub 2014 Aug 25.

PMID:
25154875

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