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Items: 28

1.

Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.

Kaisar MMM, Ritter M, Del Fresno C, Jónasdóttir HS, van der Ham AJ, Pelgrom LR, Schramm G, Layland LE, Sancho D, Prazeres da Costa C, Giera M, Yazdanbakhsh M, Everts B.

PLoS Biol. 2018 Apr 18;16(4):e2005504. doi: 10.1371/journal.pbio.2005504. [Epub ahead of print]

2.

Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity.

Alsina-Beauchamp D, Escós A, Fajardo P, González-Romero D, Díaz-Mora E, Risco A, Martín-Serrano MA, Del Fresno C, Dominguez-Andrés J, Aparicio N, Zur R, Shpiro N, Brown GD, Ardavín C, Netea MG, Alemany S, Sanz-Ezquerro JJ, Cuenda A.

EMBO Mol Med. 2018 Apr 16. pii: e8485. doi: 10.15252/emmm.201708485. [Epub ahead of print]

3.

Neutrophils acROSs the Enemy Lines.

Del Fresno C, Hidalgo A.

Immunity. 2017 Mar 21;46(3):335-337. doi: 10.1016/j.immuni.2017.03.003.

4.

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection.

Iborra S, Martínez-López M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martín Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, Sancho D.

Immunity. 2016 Oct 18;45(4):788-801. doi: 10.1016/j.immuni.2016.09.012. Epub 2016 Oct 11.

5.

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1+ Dendritic Cells.

Iborra S, Martínez-López M, Khouili SC, Enamorado M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Sancho D.

Immunity. 2016 Oct 18;45(4):847-860. doi: 10.1016/j.immuni.2016.08.019. Epub 2016 Sep 27.

6.

SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicans.

Blanco-Menéndez N, Del Fresno C, Fernandes S, Calvo E, Conde-Garrosa R, Kerr WG, Sancho D.

J Immunol. 2015 Nov 1;195(9):4466-4478. doi: 10.4049/jimmunol.1402874. Epub 2015 Sep 28.

7.

Salvadora persica agro-ecological suitability for oil production in Argentine dryland salinity.

Falasca S, Pitta-Alvarez S, del Fresno CM.

Sci Total Environ. 2015 Dec 15;538:844-54. doi: 10.1016/j.scitotenv.2015.08.082. Epub 2015 Sep 28.

PMID:
26348151
8.

NFκB2/p100 is a key factor for endotoxin tolerance in human monocytes: a demonstration using primary human monocytes from patients with sepsis.

Cubillos-Zapata C, Hernández-Jiménez E, Toledano V, Esteban-Burgos L, Fernández-Ruíz I, Gómez-Piña V, Del Fresno C, Siliceo M, Prieto-Chinchiña P, Pérez de Diego R, Boscá L, Fresno M, Arnalich F, López-Collazo E.

J Immunol. 2014 Oct 15;193(8):4195-202. doi: 10.4049/jimmunol.1400721. Epub 2014 Sep 15.

9.

Pathophysiology of endotoxin tolerance: mechanisms and clinical consequences.

López-Collazo E, del Fresno C.

Crit Care. 2013 Nov 14;17(6):242. doi: 10.1186/cc13110. Review.

10.

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation.

López-Bravo M, Minguito de la Escalera M, Domínguez PM, González-Cintado L, del Fresno C, Martín P, Martínez del Hoyo G, Ardavín C.

J Allergy Clin Immunol. 2013 Dec;132(6):1409-19. doi: 10.1016/j.jaci.2013.08.039. Epub 2013 Oct 17.

PMID:
24139608
11.

Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.

del Fresno C, Soulat D, Roth S, Blazek K, Udalova I, Sancho D, Ruland J, Ardavín C.

Immunity. 2013 Jun 27;38(6):1176-86. doi: 10.1016/j.immuni.2013.05.010. Epub 2013 Jun 13.

12.

p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation.

Risco A, del Fresno C, Mambol A, Alsina-Beauchamp D, MacKenzie KF, Yang HT, Barber DF, Morcelle C, Arthur JS, Ley SC, Ardavin C, Cuenda A.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11200-5. doi: 10.1073/pnas.1207290109. Epub 2012 Jun 25.

13.

Monocytes as effector cells: activated Ly-6C(high) mouse monocytes migrate to the lymph nodes through the lymph and cross-present antigens to CD8+ T cells.

Leirião P, del Fresno C, Ardavín C.

Eur J Immunol. 2012 Aug;42(8):2042-51. doi: 10.1002/eji.201142166. Epub 2012 Jul 9.

14.

Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM-1-PI3K-NF-κB pathway.

Gómez-Piña V, Martínez E, Fernández-Ruíz I, Del Fresno C, Soares-Schanoski A, Jurado T, Siliceo M, Toledano V, Fernández-Palomares R, García-Rio F, Arnalich F, Biswas SK, López-Collazo E.

J Leukoc Biol. 2012 Jun;91(6):933-45. doi: 10.1189/jlb.0711340. Epub 2012 Mar 29.

PMID:
22459945
15.

Translocated LPS might cause endotoxin tolerance in circulating monocytes of cystic fibrosis patients.

del Campo R, Martínez E, del Fresno C, Alenda R, Gómez-Piña V, Fernández-Ruíz I, Siliceo M, Jurado T, Toledano V, Arnalich F, García-Río F, López-Collazo E.

PLoS One. 2011;6(12):e29577. doi: 10.1371/journal.pone.0029577. Epub 2011 Dec 28.

16.

Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients.

del Fresno C, García-Rio F, Gómez-Piña V, Soares-Schanoski A, Fernández-Ruíz I, Jurado T, Kajiji T, Shu C, Marín E, Gutierrez del Arroyo A, Prados C, Arnalich F, Fuentes-Prior P, Biswas SK, López-Collazo E.

J Immunol. 2009 May 15;182(10):6494-507. doi: 10.4049/jimmunol.0803350. Erratum in: J Immunol. 2009 Aug 1;183(3):2194. Biswas, Subrha K [corrected to Biswas, Subhra K].

17.

Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: down-regulation of TREM-1 as putative underlying mechanism.

del Fresno C, Gómez-Piña V, Lores V, Soares-Schanoski A, Fernández-Ruiz I, Rojo B, Alvarez-Sala R, Caballero-Garrido E, García F, Veliz T, Arnalich F, Fuentes-Prior P, García-Río F, López-Collazo E.

PLoS One. 2008 Jul 16;3(7):e2667. doi: 10.1371/journal.pone.0002667.

18.

Position-dependent expression of GADD45alpha in rat brain tumours.

Brú A, del Fresno C, Soares-Schanoski A, Albertos S, Brú I, Porres A, Rollán-Landeras E, Dopazo A, Casero D, Gómez-Piña V, García L, Arnalich F, Alvarez R, Rodríguez-Rojas A, Fuentes-Prior P, López-Collazo E.

Med Oncol. 2007;24(4):436-44.

PMID:
17917095
19.

Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance.

Biswas SK, Bist P, Dhillon MK, Kajiji T, Del Fresno C, Yamamoto M, Lopez-Collazo E, Akira S, Tergaonkar V.

J Immunol. 2007 Sep 15;179(6):4083-92.

20.

Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes.

Gómez-Piña V, Soares-Schanoski A, Rodríguez-Rojas A, Del Fresno C, García F, Vallejo-Cremades MT, Fernández-Ruiz I, Arnalich F, Fuentes-Prior P, López-Collazo E.

J Immunol. 2007 Sep 15;179(6):4065-73.

21.

Inflammatory responses associated with acute coronary syndrome up-regulate IRAK-M and induce endotoxin tolerance in circulating monocytes.

del Fresno C, Soler-Rangel L, Soares-Schanoski A, Gómez-Piña V, González-León MC, Gómez-García L, Mendoza-Barberá E, Rodríguez-Rojas A, García F, Fuentes-Prior P, Arnalich F, López-Collazo E.

J Endotoxin Res. 2007;13(1):39-52.

PMID:
17621545
22.

6-Methylprednisolone down-regulates IRAK-M in human and murine osteoclasts and boosts bone-resorbing activity: a putative mechanism for corticoid-induced osteoporosis.

Soares-Schanoski A, Gómez-Piña V, del Fresno C, Rodríguez-Rojas A, García F, Glaría A, Sánchez M, Vallejo-Cremades MT, Baos R, Fuentes-Prior P, Arnalich F, López-Collazo E.

J Leukoc Biol. 2007 Sep;82(3):700-9. Epub 2007 Jun 18.

PMID:
17576820
23.

Nitric oxide induces SOCS-1 expression in human monocytes in a TNF-alpha-dependent manner.

González-León MC, Soares-Schanoski A, del Fresno C, Cimadevila A, Goméz-Piña V, Mendoza-Barberá E, García F, Marín E, Arnalich F, Fuentes-Prior P, López-Collazo E.

J Endotoxin Res. 2006;12(5):296-306.

PMID:
17059693
24.

Pathophysiology of interleukin-1 receptor-associated kinase-M: implications in refractory state.

López-Collazo E, Fuentes-Prior P, Arnalich F, del Fresno C.

Curr Opin Infect Dis. 2006 Jun;19(3):237-44. Review.

PMID:
16645484
25.

Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4.

del Fresno C, Otero K, Gómez-García L, González-León MC, Soler-Ranger L, Fuentes-Prior P, Escoll P, Baos R, Caveda L, García F, Arnalich F, López-Collazo E.

J Immunol. 2005 Mar 1;174(5):3032-40.

26.

Nitric oxide activates the expression of IRAK-M via the release of TNF-alpha in human monocytes.

del Fresno C, Gómez-García L, Caveda L, Escoll P, Arnalich F, Zamora R, López-Collazo E.

Nitric Oxide. 2004 Jun;10(4):213-20.

PMID:
15275867
27.

Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients.

Escoll P, del Fresno C, García L, Vallés G, Lendínez MJ, Arnalich F, López-Collazo E.

Biochem Biophys Res Commun. 2003 Nov 14;311(2):465-72.

PMID:
14592437
28.

Penetration power of antiseptic creams ("in vitro" model with pig skin).

Garcia Torres V, Herruzo R, Santos Heredero FX, Lenguas F, Martinez Ratero S, del Fresno C.

Acta Chir Plast. 1991;33(2):65-71.

PMID:
1718107

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