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Items: 1 to 50 of 53

1.

Attenuated Bacteria as Immunotherapeutic Tools for Cancer Treatment.

Kaimala S, Al-Sbiei A, Cabral-Marques O, Fernandez-Cabezudo MJ, Al-Ramadi BK.

Front Oncol. 2018 May 1;8:136. doi: 10.3389/fonc.2018.00136. eCollection 2018.

2.

Cholinergic Activation Enhances Resistance to Oral Salmonella Infection by Modulating Innate Immune Defense Mechanisms at the Intestinal Barrier.

Al-Barazie RM, Bashir GH, Qureshi MM, Mohamed YA, Al-Sbiei A, Tariq S, Lammers WJ, Al-Ramadi BK, Fernandez-Cabezudo MJ.

Front Immunol. 2018 Mar 19;9:551. doi: 10.3389/fimmu.2018.00551. eCollection 2018.

3.

CD40 ligand deficiency causes functional defects of peripheral neutrophils that are improved by exogenous IFN-γ.

Cabral-Marques O, França TT, Al-Sbiei A, Schimke LF, Khan TA, Feriotti C, da Costa TA, Junior OR, Weber CW, Ferreira JF, Tavares FS, Valente C, Di Gesu RSW, Iqbal A, Riemekasten G, Amarante-Mendes GP, Marzagão Barbuto JA, Costa-Carvalho BT, Pereira PVS, Fernandez-Cabezudo MJ, Calich VLG, Notarangelo LD, Torgerson TR, Al-Ramadi BK, Ochs HD, Condino-Neto A.

J Allergy Clin Immunol. 2018 Mar 5. pii: S0091-6749(18)30318-X. doi: 10.1016/j.jaci.2018.02.026. [Epub ahead of print]

PMID:
29518426
4.

Clinical, immunologic, and genetic spectrum of 696 patients with combined immunodeficiency.

Abolhassani H, Chou J, Bainter W, Platt CD, Tavassoli M, Momen T, Tavakol M, Eslamian MH, Gharagozlou M, Movahedi M, Ghadami M, Hamidieh AA, Azizi G, Yazdani R, Afarideh M, Ghajar A, Havaei A, Chavoshzadeh Z, Mahdaviani SA, Cheraghi T, Behniafard N, Amin R, Aleyasin S, Faridhosseini R, Jabbari-Azad F, Nabavi M, Bemanian MH, Arshi S, Molatefi R, Sherkat R, Mansouri M, Mesdaghi M, Babaie D, Mohammadzadeh I, Ghaffari J, Shafiei A, Kalantari N, Ahanchian H, Khoshkhui M, Soheili H, Dabbaghzadeh A, Shirkani A, Nasiri Kalmarzi R, Mortazavi SH, Tafaroji J, Khalili A, Mohammadi J, Negahdari B, Joghataei MT, Al-Ramadi BK, Picard C, Parvaneh N, Rezaei N, Chatila TA, Massaad MJ, Keles S, Hammarström L, Geha RS, Aghamohammadi A.

J Allergy Clin Immunol. 2018 Apr;141(4):1450-1458. doi: 10.1016/j.jaci.2017.06.049. Epub 2017 Sep 12.

PMID:
28916186
5.

The IL-6/STAT3 Signaling Pathway Is an Early Target of Manuka Honey-Induced Suppression of Human Breast Cancer Cells.

Aryappalli P, Al-Qubaisi SS, Attoub S, George JA, Arafat K, Ramadi KB, Mohamed YA, Al-Dhaheri MM, Al-Sbiei A, Fernandez-Cabezudo MJ, Al-Ramadi BK.

Front Oncol. 2017 Aug 14;7:167. doi: 10.3389/fonc.2017.00167. eCollection 2017.

6.

Metallic nanoparticles to eradicate bacterial bone infection.

Qadri S, Haik Y, Mensah-Brown E, Bashir G, Fernandez-Cabezudo MJ, Al-Ramadi BK.

Nanomedicine. 2017 Oct;13(7):2241-2250. doi: 10.1016/j.nano.2017.05.013. Epub 2017 Jun 7.

PMID:
28599795
7.

Cholinergic Stimulation Prevents the Development of Autoimmune Diabetes: Evidence for the Modulation of Th17 Effector Cells via an IFNγ-Dependent Mechanism.

George JA, Bashir G, Qureshi MM, Mohamed YA, Azzi J, Al-Ramadi BK, Fernández-Cabezudo MJ.

Front Immunol. 2016 Oct 13;7:419. eCollection 2016.

8.

Deficiency of mitochondrial modulator MCJ promotes chemoresistance in breast cancer.

Fernández-Cabezudo MJ, Faour I, Jones K, Champagne DP, Jaloudi MA, Mohamed YA, Bashir G, Almarzooqi S, Albawardi A, Hashim MJ, Roberts TS, El-Salhat H, El-Taji H, Kassis A, O'Sullivan DE, Christensen BC, DeGregori J, Al-Ramadi BK, Rincon M.

JCI Insight. 2016 May 19;1(7). pii: e86873.

9.

Acute systemic exposure to silver-based nanoparticles induces hepatotoxicity and NLRP3-dependent inflammation.

Ramadi KB, Mohamed YA, Al-Sbiei A, Almarzooqi S, Bashir G, Al Dhanhani A, Sarawathiamma D, Qadri S, Yasin J, Nemmar A, Fernandez-Cabezudo MJ, Haik Y, Al-Ramadi BK.

Nanotoxicology. 2016 Oct;10(8):1061-74. doi: 10.3109/17435390.2016.1163743. Epub 2016 Apr 14.

PMID:
26956548
10.

A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.

Jabara HH, Boyden SE, Chou J, Ramesh N, Massaad MJ, Benson H, Bainter W, Fraulino D, Rahimov F, Sieff C, Liu ZJ, Alshemmari SH, Al-Ramadi BK, Al-Dhekri H, Arnaout R, Abu-Shukair M, Vatsayan A, Silver E, Ahuja S, Davies EG, Sola-Visner M, Ohsumi TK, Andrews NC, Notarangelo LD, Fleming MD, Al-Herz W, Kunkel LM, Geha RS.

Nat Genet. 2016 Jan;48(1):74-8. doi: 10.1038/ng.3465. Epub 2015 Dec 7.

11.

Salmonella-mediated tumor regression involves targeting of tumor myeloid suppressor cells causing a shift to M1-like phenotype and reduction in suppressive capacity.

Kaimala S, Mohamed YA, Nader N, Issac J, Elkord E, Chouaib S, Fernandez-Cabezudo MJ, Al-Ramadi BK.

Cancer Immunol Immunother. 2014 Jun;63(6):587-99. doi: 10.1007/s00262-014-1543-x. Epub 2014 Mar 26.

PMID:
24668365
12.

Phenotypic alterations, clinical impact and therapeutic potential of regulatory T cells in cancer.

Chaudhary B, Abd Al Samid M, al-Ramadi BK, Elkord E.

Expert Opin Biol Ther. 2014 Jul;14(7):931-45. doi: 10.1517/14712598.2014.900539. Epub 2014 Mar 24. Review.

PMID:
24661020
13.

Intravenous administration of manuka honey inhibits tumor growth and improves host survival when used in combination with chemotherapy in a melanoma mouse model.

Fernandez-Cabezudo MJ, El-Kharrag R, Torab F, Bashir G, George JA, El-Taji H, al-Ramadi BK.

PLoS One. 2013;8(2):e55993. doi: 10.1371/journal.pone.0055993. Epub 2013 Feb 7.

14.

Helios expression in FoxP3(+) T regulatory cells.

Elkord E, Al-Ramadi BK.

Expert Opin Biol Ther. 2012 Nov;12(11):1423-5. doi: 10.1517/14712598.2012.711310. Epub 2012 Jul 25.

PMID:
22827571
15.

IFNγ expression by an attenuated strain of Salmonella enterica serovar Typhimurium improves vaccine efficacy in susceptible TLR4-defective C3H/HeJ mice.

Al-Ojali SM, Tara Moore CB, Fernandez-Cabezudo MJ, Al-Ramadi BK.

Med Microbiol Immunol. 2013 Feb;202(1):49-61. doi: 10.1007/s00430-012-0248-z. Epub 2012 Jun 10.

PMID:
22684724
16.

Enhancement of the anti-Salmonella immune response in CD154-deficient mice by an attenuated, IFN-γ-expressing, strain of Salmonella enterica serovar Typhimurium.

Al-Ojali SM, Moore CB, Fernandez-Cabezudo MJ, Al-Ramadi BK.

Microb Pathog. 2012 Jun;52(6):326-35. doi: 10.1016/j.micpath.2012.03.002. Epub 2012 Mar 13.

PMID:
22445817
17.

Differential outcome of infection with attenuated Salmonella in MyD88-deficient mice is dependent on the route of administration.

Issac JM, Sarawathiamma D, Al-Ketbi MI, Azimullah S, Al-Ojali SM, Mohamed YA, Flavell RA, Fernandez-Cabezudo MJ, al-Ramadi BK.

Immunobiology. 2013 Jan;218(1):52-63. doi: 10.1016/j.imbio.2012.02.001. Epub 2012 Feb 10.

PMID:
22386951
18.

Association between birth order and immunological parameters?

Bernsen RM, al-Ramadi BK.

Placenta. 2011 Nov;32(11):922. doi: 10.1016/j.placenta.2011.05.004. No abstract available.

PMID:
21641032
19.

Cholinergic stimulation of the immune system protects against lethal infection by Salmonella enterica serovar Typhimurium.

Fernandez-Cabezudo MJ, Lorke DE, Azimullah S, Mechkarska M, Hasan MY, Petroianu GA, al-Ramadi BK.

Immunology. 2010 Jul;130(3):388-98. doi: 10.1111/j.1365-2567.2009.03238.x. Epub 2010 Apr 8.

20.

The organophosphate paraoxon has no demonstrable effect on the murine immune system following subchronic low dose exposure.

Fernandez-Cabezudo MJ, Azimullah S, Nurulain SM, Mechkarska M, Lorke DE, Hasan MY, Petroianu GA, Al-Ramadi BK.

Int J Immunopathol Pharmacol. 2008 Oct-Dec;21(4):891-901.

PMID:
19144274
21.

Potent anti-tumor activity of systemically-administered IL2-expressing Salmonella correlates with decreased angiogenesis and enhanced tumor apoptosis.

al-Ramadi BK, Fernandez-Cabezudo MJ, El-Hasasna H, Al-Salam S, Bashir G, Chouaib S.

Clin Immunol. 2009 Jan;130(1):89-97. doi: 10.1016/j.clim.2008.08.021. Epub 2008 Oct 11.

PMID:
18849195
22.

Attenuated bacteria as effectors in cancer immunotherapy.

Al-Ramadi BK, Fernandez-Cabezudo MJ, El-Hasasna H, Al-Salam S, Attoub S, Xu D, Chouaib S.

Ann N Y Acad Sci. 2008 Sep;1138:351-7. doi: 10.1196/annals.1414.036.

PMID:
18837910
23.

Modulation of macrophage proinflammatory functions by cytokine-expressing Salmonella vectors.

Fernandez-Cabezudo MJ, Mechkarska M, Azimullah S, al-Ramadi BK.

Clin Immunol. 2009 Jan;130(1):51-60. doi: 10.1016/j.clim.2008.08.017. Epub 2008 Oct 2.

PMID:
18835224
24.

Pronounced susceptibility to infection by Salmonella enterica serovar Typhimurium in mice chronically exposed to lead correlates with a shift to Th2-type immune responses.

Fernandez-Cabezudo MJ, Ali SA, Ullah A, Hasan MY, Kosanovic M, Fahim MA, Adem A, al-Ramadi BK.

Toxicol Appl Pharmacol. 2007 Feb 1;218(3):215-26. Epub 2006 Nov 18.

PMID:
17196234
25.

Does paternal antigen-induced secretion of interleukin-10 by T regulatory cells mediate the birth order effect?

Bernsen RM, Nagelkerke NJ, al-Ramadi BK.

Med Hypotheses. 2006;67(4):740-3. Epub 2006 Jun 16.

PMID:
16781822
26.

Modulation of the systemic inflammatory response by recombinant human interleukin-11: a prospective randomized placebo controlled clinical study in patients with hematological malignancy.

Ellis M, Hedstrom U, Frampton C, Alizadeh H, Kristensen J, Shammas FV, al-Ramadi BK.

Clin Immunol. 2006 Aug;120(2):129-37. Epub 2006 Apr 27.

PMID:
16644288
27.

CD154 is essential for protective immunity in experimental salmonella infection: evidence for a dual role in innate and adaptive immune responses.

al-Ramadi BK, Fernandez-Cabezudo MJ, Ullah A, El-Hasasna H, Flavell RA.

J Immunol. 2006 Jan 1;176(1):496-506.

28.

Evidence for the requirement for CD40-CD154 interactions in resistance to infections with attenuated Salmonella.

Fernandez-Cabezudo MJ, Ullah A, Flavell RA, Al-Ramadi BK.

J Endotoxin Res. 2005;11(6):395-9.

PMID:
16303097
29.
30.

Evidence for a dual pathway of activation in CD43-stimulated Th2 cells: differential requirement for the Lck tyrosine kinase.

Fernandez-Cabezudo MJ, Vijayasarathy C, Pflugh DL, Bothwell AL, al-Ramadi BK.

Int Immunol. 2004 Aug;16(8):1215-23. Epub 2004 Jul 5.

PMID:
15237112
31.

Poor survival but high immunogenicity of IL-2-expressing Salmonella typhimurium in inherently resistant mice.

al-Ramadi BK, Bashir G, Rizvi TA, Fernandez-Cabezudo MJ.

Microbes Infect. 2004 Apr;6(4):350-9.

PMID:
15050962
32.

Activation of innate immune responses by IL-2-expressing Salmonella typhimurium is independent of Toll-like receptor 4.

al-Ramadi BK, Fernandez-Cabezudo MJ, Mustafa N, Xu D.

Mol Immunol. 2004 Jan;40(10):671-9.

PMID:
14644093
33.

Alpha tocopherol protects against immunosuppressive and immunotoxic effects of lead.

Fernandez-Cabezudo MJ, Hasan MY, Mustafa N, El-Sharkawy RT, Fahim MA, Al-Ramadi BK.

Free Radic Res. 2003 Apr;37(4):437-45.

PMID:
12747738
34.

Induction of innate immunity by IL-2-expressing Salmonella confers protection against lethal infection.

al-Ramadi BK, Mustafa N, AbouHaidar M, Fernandez-Cabezudo MJ.

Mol Immunol. 2003 Mar;39(13):763-70.

PMID:
12617991
35.

Cytokine expression by attenuated intracellular bacteria regulates the immune response to infection: the Salmonella model.

al-Ramadi BK, Adeghate E, Mustafa N, Ponery AS, Fernandez-Cabezudo MJ.

Mol Immunol. 2002 May;38(12-13):931-40.

PMID:
12009571
36.

The Src-protein tyrosine kinase Lck is required for IL-1-mediated costimulatory signaling in Th2 cells.

al-Ramadi BK, Welte T, Fernandez-Cabezudo MJ, Galadari S, Dittel B, Fu XY, Bothwell AL.

J Immunol. 2001 Dec 15;167(12):6827-33.

37.

Influence of vector-encoded cytokines on anti-Salmonella immunity: divergent effects of interleukin-2 and tumor necrosis factor alpha.

al-Ramadi BK, Al-Dhaheri MH, Mustafa N, Abouhaidar M, Xu D, Liew FY, Lukic ML, Fernandez-Cabezudo MJ.

Infect Immun. 2001 Jun;69(6):3980-8.

38.

The PTK-STAT signaling pathway has essential roles in T-cell activation in response to antigen stimulation.

Welte T, Leitenberg D, Dittel BN, al-Ramadi BK, Hansen WR, Xie B, Janeway CA Jr, Bothwell AL, Bottomly K, Fu XY.

Cold Spring Harb Symp Quant Biol. 1999;64:291-302. Review. No abstract available.

PMID:
11232299
39.

STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation.

Welte T, Leitenberg D, Dittel BN, al-Ramadi BK, Xie B, Chin YE, Janeway CA Jr, Bothwell AL, Bottomly K, Fu XY.

Science. 1999 Jan 8;283(5399):222-5.

40.

Cell-cycle arrest and apoptosis hypersusceptibility as a consequence of Lck deficiency in nontransformed T lymphocytes.

al-Ramadi BK, Zhang H, Bothwell AL.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12498-503.

41.

Analysis of the expression of peptide-major histocompatibility complexes using high affinity soluble divalent T cell receptors.

O'Herrin SM, Lebowitz MS, Bieler JG, al-Ramadi BK, Utz U, Bothwell AL, Schneck JP.

J Exp Med. 1997 Oct 20;186(8):1333-45.

42.

Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma.

Nakamura T, Lee RK, Nam SY, Al-Ramadi BK, Koni PA, Bottomly K, Podack ER, Flavell RA.

J Immunol. 1997 Mar 1;158(5):2090-8.

PMID:
9036953
43.

Deficient expression of p56(lck) in Th2 cells leads to partial TCR signaling and a dysregulation in lymphokine mRNA levels.

al-Ramadi BK, Nakamura T, Leitenberg D, Bothwell AL.

J Immunol. 1996 Dec 1;157(11):4751-61.

PMID:
8943376
44.

Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.

al-Ramadi BK, Jelonek MT, Boyd LF, Margulies DH, Bothwell AL.

J Immunol. 1995 Jul 15;155(2):662-73.

PMID:
7541822
45.

Response.

Corr M, Slanetz AE, Boyd LF, Jelonek MT, Khilko S, Al-Ramadi BK, Kim YS, Maher SE, Bothwell AL, Margulies DH.

Science. 1995 Apr 7;268(5207):117. No abstract available.

PMID:
17755235
46.
47.

T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity.

Corr M, Slanetz AE, Boyd LF, Jelonek MT, Khilko S, al-Ramadi BK, Kim YS, Maher SE, Bothwell AL, Margulies DH.

Science. 1994 Aug 12;265(5174):946-9.

PMID:
8052850
48.

Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs.

Rudensky AYu, Preston-Hurlburt P, al-Ramadi BK, Rothbard J, Janeway CA Jr.

Nature. 1992 Oct 1;359(6394):429-31.

PMID:
1328884
49.

Immunosuppression induced by nitric oxide and its inhibition by interleukin-4.

al-Ramadi BK, Meissler JJ Jr, Huang D, Eisenstein TK.

Eur J Immunol. 1992 Sep;22(9):2249-54.

PMID:
1516618
50.

Immunosuppression induced by attenuated Salmonella: effect of LPS responsiveness on development of suppression.

al-Ramadi BK, Greene JM, Meissler JJ Jr, Eisenstein TK.

Microb Pathog. 1992 Apr;12(4):267-78.

PMID:
1630297

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