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Items: 1 to 50 of 55

1.

The glycosomal alkyl-dihydroxyacetonephosphate synthase TbADS is essential for the synthesis of ether glycerophospholipids in procyclic trypanosomes.

Lee S, Cheung-See-Kit M, Williams TA, Yamout N, Zufferey R.

Exp Parasitol. 2018 Feb;185:71-78. doi: 10.1016/j.exppara.2018.01.014.

PMID:
29355496
2.

Lipidomics and anti-trypanosomatid chemotherapy.

Biagiotti M, Dominguez S, Yamout N, Zufferey R.

Clin Transl Med. 2017 Dec;6(1):27. doi: 10.1186/s40169-017-0160-7. Epub 2017 Aug 1. Review.

3.

The Trypanosoma brucei dihydroxyacetonephosphate acyltransferase TbDAT is dispensable for normal growth but important for synthesis of ether glycerophospholipids.

Zufferey R, Pirani K, Cheung-See-Kit M, Lee S, Williams TA, Chen DG, Hossain MF.

PLoS One. 2017 Jul 17;12(7):e0181432. doi: 10.1371/journal.pone.0181432. eCollection 2017.

4.

The Glycerol-3-Phosphate Acyltransferase TbGAT is Dispensable for Viability and the Synthesis of Glycerolipids in Trypanosoma brucei.

Patel N, Pirani KA, Zhu T, Cheung-See-Kit M, Lee S, Chen DG, Zufferey R.

J Eukaryot Microbiol. 2016 Sep;63(5):598-609. doi: 10.1111/jeu.12309. Epub 2016 Mar 8.

5.

In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity.

Zufferey R.

J Vis Exp. 2016 Jan 5;(107). doi: 10.3791/53302.

6.

Characterization of Leishmania major phosphatidylethanolamine methyltransferases LmjPEM1 and LmjPEM2 and their inhibition by choline analogs.

Bibis SS, Dahlstrom K, Zhu T, Zufferey R.

Mol Biochem Parasitol. 2014 Sep;196(2):90-9. doi: 10.1016/j.molbiopara.2014.08.005. Epub 2014 Aug 29.

7.

Characterization of a compensatory mutant of Leishmania major that lacks ether lipids but exhibits normal growth, and G418 and hygromycin resistance.

Zufferey R, Bibis SS, Zhu T, Dhalladoo S.

Exp Parasitol. 2012 Mar;130(3):200-4. doi: 10.1016/j.exppara.2012.01.008. Epub 2012 Jan 24.

PMID:
22306069
8.

The N-terminal domain and glycosomal localization of Leishmania initial acyltransferase LmDAT are important for lipophosphoglycan synthesis.

Al-Ani GK, Patel N, Pirani KA, Zhu T, Dhalladoo S, Zufferey R.

PLoS One. 2011;6(11):e27802. doi: 10.1371/journal.pone.0027802. Epub 2011 Nov 17.

9.

A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2.

Dusonchet J, Kochubey O, Stafa K, Young SM Jr, Zufferey R, Moore DJ, Schneider BL, Aebischer P.

J Neurosci. 2011 Jan 19;31(3):907-12. doi: 10.1523/JNEUROSCI.5092-10.2011.

10.

PfNT2, a permease of the equilibrative nucleoside transporter family in the endoplasmic reticulum of Plasmodium falciparum.

Downie MJ, El Bissati K, Bobenchik AM, Nic Lochlainn L, Amerik A, Zufferey R, Kirk K, Ben Mamoun C.

J Biol Chem. 2010 Jul 2;285(27):20827-33. doi: 10.1074/jbc.M110.118489. Epub 2010 May 3.

11.

Leishmania dihydroxyacetonephosphate acyltransferase LmDAT is important for ether lipid biosynthesis but not for the integrity of detergent resistant membranes.

Zufferey R, Al-Ani GK, Dunlap K.

Mol Biochem Parasitol. 2009 Dec;168(2):177-85. doi: 10.1016/j.molbiopara.2009.08.006. Epub 2009 Aug 29.

12.

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF.

Emborg ME, Moirano J, Raschke J, Bondarenko V, Zufferey R, Peng S, Ebert AD, Joers V, Roitberg B, Holden JE, Koprich J, Lipton J, Kordower JH, Aebischer P.

Neurobiol Dis. 2009 Nov;36(2):303-11. doi: 10.1016/j.nbd.2009.07.022. Epub 2009 Aug 4.

13.

Viral vectors, animal models and new therapies for Parkinson's disease.

Schneider B, Zufferey R, Aebischer P.

Parkinsonism Relat Disord. 2008;14 Suppl 2:S169-71. doi: 10.1016/j.parkreldis.2008.04.024. Epub 2008 Jun 27. Review.

PMID:
18585946
14.

Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease.

O'Keeffe FE, Scott SA, Tyers P, O'Keeffe GW, Dalley JW, Zufferey R, Caldwell MA.

Brain. 2008 Mar;131(Pt 3):630-41. doi: 10.1093/brain/awm340. Epub 2008 Jan 17.

PMID:
18202103
15.

Correlation between recent thymic emigrants and CD31+ (PECAM-1) CD4+ T cells in normal individuals during aging and in lymphopenic children.

Junge S, Kloeckener-Gruissem B, Zufferey R, Keisker A, Salgo B, Fauchere JC, Scherer F, Shalaby T, Grotzer M, Siler U, Seger R, Güngör T.

Eur J Immunol. 2007 Nov;37(11):3270-80.

16.

Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy.

Capowski EE, Schneider BL, Ebert AD, Seehus CR, Szulc J, Zufferey R, Aebischer P, Svendsen CN.

J Neurosci Methods. 2007 Jul 30;163(2):338-49. Epub 2007 Mar 3.

PMID:
17397931
17.

The plasma membrane permease PfNT1 is essential for purine salvage in the human malaria parasite Plasmodium falciparum.

El Bissati K, Zufferey R, Witola WH, Carter NS, Ullman B, Ben Mamoun C.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9286-91. Epub 2006 Jun 2.

20.

Unraveling the mode of action of the antimalarial choline analog G25 in Plasmodium falciparum and Saccharomyces cerevisiae.

Roggero R, Zufferey R, Minca M, Richier E, Calas M, Vial H, Ben Mamoun C.

Antimicrob Agents Chemother. 2004 Aug;48(8):2816-24.

21.

Salivary glands and gene therapy: the mouth waters.

Zufferey R, Aebischer P.

Gene Ther. 2004 Oct;11(19):1425-6. No abstract available.

PMID:
15269715
22.

Reexamining the role of choline transporter-like (Ctlp) proteins in choline transport.

Zufferey R, Santiago TC, Brachet V, Ben Mamoun C.

Neurochem Res. 2004 Feb;29(2):461-7.

PMID:
15002745
23.
24.

The Plasmodium falciparum PfGatp is an endoplasmic reticulum membrane protein important for the initial step of malarial glycerolipid synthesis.

Santiago TC, Zufferey R, Mehra RS, Coleman RA, Mamoun CB.

J Biol Chem. 2004 Mar 5;279(10):9222-32. Epub 2003 Dec 10.

25.

Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.

Zufferey R, Allen S, Barron T, Sullivan DR, Denny PW, Almeida IC, Smith DF, Turco SJ, Ferguson MA, Beverley SM.

J Biol Chem. 2003 Nov 7;278(45):44708-18. Epub 2003 Aug 27.

26.

Development of a sensitive assay for detection of replication-competent recombinant lentivirus in large-scale HIV-based vector preparations.

Escarpe P, Zayek N, Chin P, Borellini F, Zufferey R, Veres G, Kiermer V.

Mol Ther. 2003 Aug;8(2):332-41.

27.

Lentivirus-mediated transduction of connexin cDNAs shows level- and isoform-specific alterations in insulin secretion of primary pancreatic beta-cells.

Caton D, Calabrese A, Mas C, Serre-Beinier V, Charollais A, Caille D, Zufferey R, Trono D, Meda P.

J Cell Sci. 2003 Jun 1;116(Pt 11):2285-94. Epub 2003 Apr 15.

28.

Choline transport in Leishmania major promastigotes and its inhibition by choline and phosphocholine analogs.

Zufferey R, Mamoun CB.

Mol Biochem Parasitol. 2002 Nov-Dec;125(1-2):127-34.

PMID:
12467980
29.

Genetic manipulation of the pathogenic yeast Candida parapsilosis.

Nosek J, Adamíková L, Zemanová J, Tomáska L, Zufferey R, Mamoun CB.

Curr Genet. 2002 Oct;42(1):27-35. Epub 2002 Sep 20.

PMID:
12420143
30.

Production of lentiviral vectors.

Zufferey R.

Curr Top Microbiol Immunol. 2002;261:107-21. Review. No abstract available.

PMID:
11892243
31.

Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors.

Peng KW, Pham L, Ye H, Zufferey R, Trono D, Cosset FL, Russell SJ.

Gene Ther. 2001 Oct;8(19):1456-63.

32.

Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells.

Woods NB, Fahlman C, Mikkola H, Hamaguchi I, Olsson K, Zufferey R, Jacobsen SE, Trono D, Karlsson S.

Blood. 2000 Dec 1;96(12):3725-33.

33.

Lentivirus-mediated gene transfer of gp91phox corrects chronic granulomatous disease (CGD) phenotype in human X-CGD cells.

Saulnier SO, Steinhoff D, Dinauer MC, Zufferey R, Trono D, Seger RA, Hossle JP.

J Gene Med. 2000 Sep-Oct;2(5):317-25.

PMID:
11045425
34.

Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro.

Hamaguchi I, Woods NB, Panagopoulos I, Andersson E, Mikkola H, Fahlman C, Zufferey R, Carlsson L, Trono D, Karlsson S.

J Virol. 2000 Nov;74(22):10778-84.

35.
36.

Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease.

Déglon N, Tseng JL, Bensadoun JC, Zurn AD, Arsenijevic Y, Pereira de Almeida L, Zufferey R, Trono D, Aebischer P.

Hum Gene Ther. 2000 Jan 1;11(1):179-90.

PMID:
10646649
37.

Characterization of tGLP-1, a Golgi and lysosome-associated, transmembrane glycoprotein of African trypanosomes.

Lingnau A, Zufferey R, Lingnau M, Russell DG.

J Cell Sci. 1999 Sep;112 Pt 18:3061-70.

38.
39.

Transgene expression in the guinea pig cochlea mediated by a lentivirus-derived gene transfer vector.

Han JJ, Mhatre AN, Wareing M, Pettis R, Gao WQ, Zufferey RN, Trono D, Lalwani AK.

Hum Gene Ther. 1999 Jul 20;10(11):1867-73.

PMID:
10446926
40.
41.

Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery.

Zufferey R, Dull T, Mandel RJ, Bukovsky A, Quiroz D, Naldini L, Trono D.

J Virol. 1998 Dec;72(12):9873-80.

42.

Overproduction of the Bradyrhizobium japonicum c-type cytochrome subunits of the cbb3 oxidase in Escherichia coli.

Arslan E, Schulz H, Zufferey R, Künzler P, Thöny-Meyer L.

Biochem Biophys Res Commun. 1998 Oct 29;251(3):744-7.

PMID:
9790980
43.

A third-generation lentivirus vector with a conditional packaging system.

Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L.

J Virol. 1998 Nov;72(11):8463-71.

45.

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo.

Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D.

Nat Biotechnol. 1997 Sep;15(9):871-5.

PMID:
9306402
47.
49.
50.

Assembly and function of the cytochrome cbb3 oxidase subunits in Bradyrhizobium japonicum.

Zufferey R, Preisig O, Hennecke H, Thöny-Meyer L.

J Biol Chem. 1996 Apr 12;271(15):9114-9.

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