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Items: 1 to 50 of 468

1.

Implantation, removal and replacement of subretinal electronic implants for restoration of vision in patients with retinitis pigmentosa.

Gekeler K, Bartz-Schmidt KU, Sachs H, MacLaren RE, Stingl K, Zrenner E, Gekeler F.

Curr Opin Ophthalmol. 2018 May;29(3):239-247. doi: 10.1097/ICU.0000000000000467.

PMID:
29528862
2.

Optical Coherence Tomography in Patients With the Subretinal Implant Retina Implant Alpha IMS.

Kuehlewein L, Kitiratschky V, Gosheva M, Edwards TL, MacLaren RE, Groppe M, Kusnyerik A, Soare C, Jackson TL, Sun CH, Chee C, Sachs H, Stingl K, Wilhelm B, Gekeler F, Bartz-Schmidt KU, Zrenner E, Stingl K.

Ophthalmic Surg Lasers Imaging Retina. 2017 Dec 1;48(12):993-999. doi: 10.3928/23258160-20171130-06.

PMID:
29253302
3.

Ophthalmic features of cone-rod dystrophy caused by pathogenic variants in the ALMS1 gene.

Nasser F, Weisschuh N, Maffei P, Milan G, Heller C, Zrenner E, Kohl S, Kuehlewein L.

Acta Ophthalmol. 2017 Nov 30. doi: 10.1111/aos.13612. [Epub ahead of print]

PMID:
29193673
4.

ElVisML: an open data format for the exchange and storage of electrophysiological data in ophthalmology.

Strasser T, Peters T, Jägle H, Zrenner E.

Doc Ophthalmol. 2018 Feb;136(1):75-92. doi: 10.1007/s10633-017-9618-6. Epub 2017 Nov 11.

PMID:
29128949
5.

Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV8 in Nonhuman Primates.

Seitz IP, Michalakis S, Wilhelm B, Reichel FF, Ochakovski GA, Zrenner E, Ueffing M, Biel M, Wissinger B, Bartz-Schmidt KU, Peters T, Fischer MD; RD-CURE Consortium.

Invest Ophthalmol Vis Sci. 2017 Nov 1;58(13):5792-5801. doi: 10.1167/iovs.17-22473.

PMID:
29117317
6.

Assessment of the Electronic Retinal Implant Alpha AMS in Restoring Vision to Blind Patients with End-Stage Retinitis Pigmentosa.

Edwards TL, Cottriall CL, Xue K, Simunovic MP, Ramsden JD, Zrenner E, MacLaren RE.

Ophthalmology. 2018 Mar;125(3):432-443. doi: 10.1016/j.ophtha.2017.09.019. Epub 2017 Oct 27.

7.

Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations.

Stingl K, Schippert R, Bartz-Schmidt KU, Besch D, Cottriall CL, Edwards TL, Gekeler F, Greppmaier U, Kiel K, Koitschev A, Kühlewein L, MacLaren RE, Ramsden JD, Roider J, Rothermel A, Sachs H, Schröder GS, Tode J, Troelenberg N, Zrenner E.

Front Neurosci. 2017 Aug 23;11:445. doi: 10.3389/fnins.2017.00445. eCollection 2017.

8.

High Symmetry of Visual Acuity and Visual Fields in RPGR-Linked Retinitis Pigmentosa.

Bellingrath JS, Ochakovski GA, Seitz IP, Kohl S, Zrenner E, Hanig N, Prokisch H, Weber BH, Downes SM, Ramsden S, MacLaren RE, Fischer MD.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4457-4466. doi: 10.1167/iovs.17-22077.

PMID:
28863407
9.

CDHR1 mutations in retinal dystrophies.

Stingl K, Mayer AK, Llavona P, Mulahasanovic L, Rudolph G, Jacobson SG, Zrenner E, Kohl S, Wissinger B, Weisschuh N.

Sci Rep. 2017 Aug 1;7(1):6992. doi: 10.1038/s41598-017-07117-8.

10.

The Spatial Extent of Epiretinal Electrical Stimulation in the Healthy Mouse Retina.

Hosseinzadeh Z, Jalligampala A, Zrenner E, Rathbun DL.

Neurosignals. 2017;25(1):15-25. doi: 10.1159/000479459. Epub 2017 Jul 26.

11.

Temporal progression of PARP activity in the Prph2 mutant rd2 mouse: Neuroprotective effects of the PARP inhibitor PJ34.

Sahaboglu A, Sharif A, Feng L, Secer E, Zrenner E, Paquet-Durand F.

PLoS One. 2017 Jul 19;12(7):e0181374. doi: 10.1371/journal.pone.0181374. eCollection 2017.

12.

Correspondence between visual and electrical input filters of ON and OFF mouse retinal ganglion cells.

Sekhar S, Jalligampala A, Zrenner E, Rathbun DL.

J Neural Eng. 2017 Aug;14(4):046017. doi: 10.1088/1741-2552/aa722c.

PMID:
28489020
13.

Development of a Chromatic Pupillography Protocol for the First Gene Therapy Trial in Patients With CNGA3-Linked Achromatopsia.

Lisowska J, Lisowski L, Kelbsch C, Maeda F, Richter P, Kohl S, Zobor D, Strasser T, Stingl K, Zrenner E, Peters T, Wilhelm H, Fischer MD, Wilhelm B; RD-CURE Consortium.

Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1274-1282. doi: 10.1167/iovs.16-20505.

PMID:
28241315
14.

The importance of electrode position in visual electrophysiology.

Kurtenbach A, Kramer S, Strasser T, Zrenner E, Langrová H.

Doc Ophthalmol. 2017 Apr;134(2):129-134. doi: 10.1007/s10633-017-9579-9. Epub 2017 Feb 21.

PMID:
28224239
15.

Evaluation of polyesteramide (PEA) and polyester (PLGA) microspheres as intravitreal drug delivery systems in albino rats.

Peters T, Kim SW, Castro V, Stingl K, Strasser T, Bolz S, Schraermeyer U, Mihov G, Zong M, Andres-Guerrero V, Herrero Vanrell R, Dias AA, Cameron NR, Zrenner E.

Biomaterials. 2017 Apr;124:157-168. doi: 10.1016/j.biomaterials.2017.02.006. Epub 2017 Feb 7.

PMID:
28199885
16.

The Clinical Phenotype of CNGA3-Related Achromatopsia: Pretreatment Characterization in Preparation of a Gene Replacement Therapy Trial.

Zobor D, Werner A, Stanzial F, Benedicenti F, Rudolph G, Kellner U, Hamel C, Andréasson S, Zobor G, Strasser T, Wissinger B, Kohl S, Zrenner E; RD-CURE Consortium.

Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):821-832. doi: 10.1167/iovs.16-20427.

PMID:
28159970
17.

Optimal voltage stimulation parameters for network-mediated responses in wild type and rd10 mouse retinal ganglion cells.

Jalligampala A, Sekhar S, Zrenner E, Rathbun DL.

J Neural Eng. 2017 Apr;14(2):026004. doi: 10.1088/1741-2552/14/2/026004. Epub 2017 Feb 3.

PMID:
28155848
18.

Transcorneal Electrical Stimulation for Patients With Retinitis Pigmentosa: A Prospective, Randomized, Sham-Controlled Follow-up Study Over 1 Year.

Schatz A, Pach J, Gosheva M, Naycheva L, Willmann G, Wilhelm B, Peters T, Bartz-Schmidt KU, Zrenner E, Messias A, Gekeler F.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):257-269. doi: 10.1167/iovs.16-19906.

PMID:
28114587
19.

The Tuebingen Scotopic Threshold Test (TSTT).

Strasser T, Langrova H, Sundermeier S, Hillerkuss D, Stingl K, Durst W, Kurtenbach A, Zrenner E, Zobor D.

IEEE J Biomed Health Inform. 2018 Mar;22(2):607-610. doi: 10.1109/JBHI.2017.2648891. Epub 2017 Jan 5.

PMID:
28103197
20.

Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degeneration.

Sahaboglu A, Barth M, Secer E, Amo EM, Urtti A, Arsenijevic Y, Zrenner E, Paquet-Durand F.

Sci Rep. 2016 Dec 22;6:39537. doi: 10.1038/srep39537.

21.

[Transcorneal electrical stimulation in primary open angle glaucoma].

Röck T, Naycheva L, Willmann G, Wilhelm B, Peters T, Zrenner E, Bartz-Schmidt KU, Gekeler F, Schatz A.

Ophthalmologe. 2017 Oct;114(10):922-929. doi: 10.1007/s00347-016-0415-5. German.

PMID:
27966032
22.

CLINICAL PRESENTATION AND DISEASE COURSE OF USHER SYNDROME BECAUSE OF MUTATIONS IN MYO7A OR USH2A.

Testa F, Melillo P, Bonnet C, Marcelli V, de Benedictis A, Colucci R, Gallo B, Kurtenbach A, Rossi S, Marciano E, Auricchio A, Petit C, Zrenner E, Simonelli F.

Retina. 2017 Aug;37(8):1581-1590. doi: 10.1097/IAE.0000000000001389.

PMID:
27828912
23.

FUNDUS ALBIPUNCTATUS ASSOCIATED WITH CONE DYSFUNCTION.

Kuehlewein L, Nasser F, Gloeckle N, Kohl S, Zrenner E.

Retin Cases Brief Rep. 2017 Winter;11 Suppl 1:S73-S76. doi: 10.1097/ICB.0000000000000420.

PMID:
27627638
24.

Efficacy of PARP inhibition in Pde6a mutant mouse models for retinitis pigmentosa depends on the quality and composition of individual human mutations.

Jiao K, Sahaboglu A, Zrenner E, Ueffing M, Ekström PA, Paquet-Durand F.

Cell Death Discov. 2016 Jul 4;2:16040. doi: 10.1038/cddiscovery.2016.40. eCollection 2016.

25.

Transfer characteristics of subretinal visual implants: corneally recorded implant responses.

Stingl K, Bartz-Schmidt KU, Braun A, Gekeler F, Greppmaier U, Schatz A, Stett A, Strasser T, Kitiratschky V, Zrenner E.

Doc Ophthalmol. 2016 Oct;133(2):81-90. Epub 2016 Aug 10.

26.

An innovative strategy for the molecular diagnosis of Usher syndrome identifies causal biallelic mutations in 93% of European patients.

Bonnet C, Riahi Z, Chantot-Bastaraud S, Smagghe L, Letexier M, Marcaillou C, Lefèvre GM, Hardelin JP, El-Amraoui A, Singh-Estivalet A, Mohand-Saïd S, Kohl S, Kurtenbach A, Sliesoraityte I, Zobor D, Gherbi S, Testa F, Simonelli F, Banfi S, Fakin A, Glavač D, Jarc-Vidmar M, Zupan A, Battelino S, Martorell Sampol L, Claveria MA, Catala Mora J, Dad S, Møller LB, Rodriguez Jorge J, Hawlina M, Auricchio A, Sahel JA, Marlin S, Zrenner E, Audo I, Petit C.

Eur J Hum Genet. 2016 Dec;24(12):1730-1738. doi: 10.1038/ejhg.2016.99. Epub 2016 Jul 27.

27.

Tickling the retina: integration of subthreshold electrical pulses can activate retinal neurons.

Sekhar S, Jalligampala A, Zrenner E, Rathbun DL.

J Neural Eng. 2016 Aug;13(4):046004. doi: 10.1088/1741-2560/13/4/046004. Epub 2016 May 17.

PMID:
27187623
28.

The Natural History of the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) Studies: Design and Baseline Characteristics: ProgStar Report No. 1.

Strauss RW, Ho A, Muñoz B, Cideciyan AV, Sahel JA, Sunness JS, Birch DG, Bernstein PS, Michaelides M, Traboulsi EI, Zrenner E, Sadda S, Ervin AM, West S, Scholl HP; Progression of Stargardt Disease Study Group.

Ophthalmology. 2016 Apr;123(4):817-28. doi: 10.1016/j.ophtha.2015.12.009. Epub 2016 Jan 16.

PMID:
26786511
29.

Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants.

Koitschev A, Stingl K, Bartz-Schmidt KU, Braun A, Gekeler F, Greppmaier U, Sachs H, Peters T, Wilhelm B, Zrenner E, Besch D.

J Ophthalmol. 2015;2015:842518. doi: 10.1155/2015/842518. Epub 2015 Dec 10.

30.

Safety and Proof-of-Concept Study of Oral QLT091001 in Retinitis Pigmentosa Due to Inherited Deficiencies of Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT).

Scholl HP, Moore AT, Koenekoop RK, Wen Y, Fishman GA, van den Born LI, Bittner A, Bowles K, Fletcher EC, Collison FT, Dagnelie G, Degli Eposti S, Michaelides M, Saperstein DA, Schuchard RA, Barnes C, Zein W, Zobor D, Birch DG, Mendola JD, Zrenner E; RET IRD 01 Study Group.

PLoS One. 2015 Dec 10;10(12):e0143846. doi: 10.1371/journal.pone.0143846. eCollection 2015.

31.

Electrophysiology and colour: a comparison of methods to evaluate inner retinal function.

Kurtenbach A, Kernstock C, Zrenner E, Langrová H.

Doc Ophthalmol. 2015 Dec;131(3):159-67. doi: 10.1007/s10633-015-9512-z. Epub 2015 Sep 23.

PMID:
26399726
32.

[Ocular electrical stimulation: Therapeutic application and active retinal implants for hereditary retinal degenerations].

Gekeler F, Zrenner E, Bartz-Schmidt KU.

Ophthalmologe. 2015 Sep;112(9):712-9. doi: 10.1007/s00347-015-0126-3. Review. German.

PMID:
26319085
33.

Elevated vitreous body glial fibrillary acidic protein in retinal diseases.

Jünemann AG, Rejdak R, Huchzermeyer C, Maciejewski R, Grieb P, Kruse FE, Zrenner E, Rejdak K, Petzold A.

Graefes Arch Clin Exp Ophthalmol. 2015 Dec;253(12):2181-6. doi: 10.1007/s00417-015-3127-7. Epub 2015 Aug 18.

34.

Retinal functional alterations in mice lacking intermediate filament proteins glial fibrillary acidic protein and vimentin.

Wunderlich KA, Tanimoto N, Grosche A, Zrenner E, Pekny M, Reichenbach A, Seeliger MW, Pannicke T, Perez MT.

FASEB J. 2015 Dec;29(12):4815-28. doi: 10.1096/fj.15-272963. Epub 2015 Aug 6.

PMID:
26251181
35.

Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.

Kohl S, Zobor D, Chiang WC, Weisschuh N, Staller J, Gonzalez Menendez I, Chang S, Beck SC, Garcia Garrido M, Sothilingam V, Seeliger MW, Stanzial F, Benedicenti F, Inzana F, Héon E, Vincent A, Beis J, Strom TM, Rudolph G, Roosing S, Hollander AI, Cremers FP, Lopez I, Ren H, Moore AT, Webster AR, Michaelides M, Koenekoop RK, Zrenner E, Kaufman RJ, Tsang SH, Wissinger B, Lin JH.

Nat Genet. 2015 Jul;47(7):757-65. doi: 10.1038/ng.3319. Epub 2015 Jun 1.

36.

Oculomotor behavior of blind patients seeing with a subretinal visual implant.

Hafed ZM, Stingl K, Bartz-Schmidt KU, Gekeler F, Zrenner E.

Vision Res. 2016 Jan;118:119-31. doi: 10.1016/j.visres.2015.04.006. Epub 2015 Apr 20.

37.

Ketogenic diet attenuates NMDA-induced damage to rat's retinal ganglion cells in an age-dependent manner.

Zarnowski T, Choragiewicz TJ, Schuettauf F, Zrenner E, Rejdak R, Gasior M, Zarnowska I, Thaler S.

Ophthalmic Res. 2015;53(3):162-7. doi: 10.1159/000379753. Epub 2015 Mar 27.

PMID:
25832811
38.

Subretinal Visual Implant Alpha IMS--Clinical trial interim report.

Stingl K, Bartz-Schmidt KU, Besch D, Chee CK, Cottriall CL, Gekeler F, Groppe M, Jackson TL, MacLaren RE, Koitschev A, Kusnyerik A, Neffendorf J, Nemeth J, Naeem MA, Peters T, Ramsden JD, Sachs H, Simpson A, Singh MS, Wilhelm B, Wong D, Zrenner E.

Vision Res. 2015 Jun;111(Pt B):149-60. doi: 10.1016/j.visres.2015.03.001. Epub 2015 Mar 23.

39.

Multimodal assessment of choroideremia patients defines pre-treatment characteristics.

Seitz IP, Zhour A, Kohl S, Llavona P, Peter T, Wilhelm B, Zrenner E, Ueffing M, Bartz-Schmidt KU, Fischer MD.

Graefes Arch Clin Exp Ophthalmol. 2015 Dec;253(12):2143-50. doi: 10.1007/s00417-015-2976-4. Epub 2015 Mar 7.

PMID:
25744334
40.

Ophthalmological assessment of cannabis-induced persisting perception disorder: is there a direct retinal effect?

Zobor D, Strasser T, Zobor G, Schober F, Messias A, Strauss O, Batra A, Zrenner E.

Doc Ophthalmol. 2015 Apr;130(2):121-30. doi: 10.1007/s10633-015-9481-2. Epub 2015 Jan 23.

PMID:
25612939
41.

Modeling the response of ON and OFF retinal bipolar cells during electric stimulation.

Werginz P, Benav H, Zrenner E, Rattay F.

Vision Res. 2015 Jun;111(Pt B):170-81. doi: 10.1016/j.visres.2014.12.002. Epub 2014 Dec 11.

42.

DNA methylation and differential gene regulation in photoreceptor cell death.

Farinelli P, Perera A, Arango-Gonzalez B, Trifunovic D, Wagner M, Carell T, Biel M, Zrenner E, Michalakis S, Paquet-Durand F, Ekström PA.

Cell Death Dis. 2014 Dec 4;5:e1558. doi: 10.1038/cddis.2014.512.

43.

Phenotype variations of retinal dystrophies caused by mutations in the RLBP1 gene.

Hipp S, Zobor G, Glöckle N, Mohr J, Kohl S, Zrenner E, Weisschuh N, Zobor D.

Acta Ophthalmol. 2015 Jun;93(4):e281-6. doi: 10.1111/aos.12573. Epub 2014 Nov 27.

44.

Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration.

Arango-Gonzalez B, Trifunović D, Sahaboglu A, Kranz K, Michalakis S, Farinelli P, Koch S, Koch F, Cottet S, Janssen-Bienhold U, Dedek K, Biel M, Zrenner E, Euler T, Ekström P, Ueffing M, Paquet-Durand F.

PLoS One. 2014 Nov 13;9(11):e112142. doi: 10.1371/journal.pone.0112142. eCollection 2014.

45.

Synaptic remodeling generates synchronous oscillations in the degenerated outer mouse retina.

Haq W, Arango-Gonzalez B, Zrenner E, Euler T, Schubert T.

Front Neural Circuits. 2014 Sep 5;8:108. doi: 10.3389/fncir.2014.00108. eCollection 2014.

46.

Safety evaluation of "retina implant alpha IMS"--a prospective clinical trial.

Kitiratschky VB, Stingl K, Wilhelm B, Peters T, Besch D, Sachs H, Gekeler F, Bartz-Schmidt KU, Zrenner E.

Graefes Arch Clin Exp Ophthalmol. 2015 Mar;253(3):381-7. doi: 10.1007/s00417-014-2797-x. Epub 2014 Sep 16.

PMID:
25219982
47.

Exposure to high altitude alters tear film osmolarity and breakup time.

Willmann G, Schatz A, Fischer MD, Schommer K, Zrenner E, Bartz-Schmidt KU, Gekeler F, Gekeler K.

High Alt Med Biol. 2014 Jun;15(2):203-7. doi: 10.1089/ham.2013.1103.

PMID:
24971769
48.

Novel in situ activity assays for the quantitative molecular analysis of neurodegenerative processes in the retina.

Ekström PA, Ueffing M, Zrenner E, Paquet-Durand F.

Curr Med Chem. 2014;21(30):3478-93. Review.

PMID:
24934347
49.

Effects of multiple doses of voriconazole on the vision of healthy volunteers: a double-blind, placebo-controlled study.

Zrenner E, Tomaszewski K, Hamlin J, Layton G, Wood N.

Ophthalmic Res. 2014;52(1):43-52. doi: 10.1159/000359952. Epub 2014 Jun 7.

PMID:
24925440
50.

[Personalized molecular medicine: new paradigms in the treatment of cochlear implant and cancer patients].

Zenner HP, Pfister M, Friese N, Zrenner E, Röcken M.

HNO. 2014 Jul;62(7):520-4. doi: 10.1007/s00106-014-2859-8. Review. German.

PMID:
24920503

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