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Items: 1 to 50 of 558

1.

What if protective immunity is antigen-driven and not due to so-called "memory" B and T cells?

Zinkernagel RM.

Immunol Rev. 2018 May;283(1):238-246. doi: 10.1111/imr.12648. Review.

PMID:
29664570
2.

Immunological memory: lessons from the past and a look to the future.

Farber DL, Netea MG, Radbruch A, Rajewsky K, Zinkernagel RM.

Nat Rev Immunol. 2016 Feb;16(2):124-8. doi: 10.1038/nri.2016.13. Review.

PMID:
26831526
3.

On plasma cell longevity or brevity.

Zinkernagel R.

Expert Rev Vaccines. 2014 Jul;13(7):821-3. doi: 10.1586/14760584.2014.924402. Epub 2014 Jun 7.

PMID:
24909054
4.

On the Role of Dendritic Cells Versus Other Cells in Inducing Protective CD8+ T Cell Responses.

Zinkernagel RM.

Front Immunol. 2014 Feb 10;5:30. doi: 10.3389/fimmu.2014.00030. eCollection 2014. Review. No abstract available.

5.

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

Lang PA, Xu HC, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Maney SK, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, Ohashi PS, Hengartner H, Zinkernagel RM, Mak TW, Lang KS.

Cell Death Differ. 2013 Apr;20(4):649-58. doi: 10.1038/cdd.2012.167. Epub 2013 Jan 18.

6.

Immunological memory ≠ protective immunity.

Zinkernagel RM.

Cell Mol Life Sci. 2012 May;69(10):1635-40. doi: 10.1007/s00018-012-0972-y. Epub 2012 Apr 6. Review.

PMID:
22481438
7.

A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3.

Verschoor A, Neuenhahn M, Navarini AA, Graef P, Plaumann A, Seidlmeier A, Nieswandt B, Massberg S, Zinkernagel RM, Hengartner H, Busch DH.

Nat Immunol. 2011 Oct 30;12(12):1194-201. doi: 10.1038/ni.2140.

PMID:
22037602
8.

Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice.

Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, Häussinger D, Ohashi PS, Zinkernagel RM, Lang KS.

Hepatology. 2010 Jul;52(1):25-32. doi: 10.1002/hep.23640.

PMID:
20578253
9.

Long-lasting immunity by early infection of maternal-antibody-protected infants.

Navarini AA, Krzyzowska M, Lang KS, Horvath E, Hengartner H, Niemialtowski MG, Zinkernagel RM.

Eur J Immunol. 2010 Jan;40(1):113-6. doi: 10.1002/eji.200939371.

10.

Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections.

Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7107-12. doi: 10.1073/pnas.0901162106. Epub 2009 Apr 7.

11.

Recombination of retrotransposon and exogenous RNA virus results in nonretroviral cDNA integration.

Geuking MB, Weber J, Dewannieux M, Gorelik E, Heidmann T, Hengartner H, Zinkernagel RM, Hangartner L.

Science. 2009 Jan 16;323(5912):393-6. doi: 10.1126/science.1167375.

12.

Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection.

McCoy KD, Stoel M, Stettler R, Merky P, Fink K, Senn BM, Schaer C, Massacand J, Odermatt B, Oettgen HC, Zinkernagel RM, Bos NA, Hengartner H, Macpherson AJ, Harris NL.

Cell Host Microbe. 2008 Oct 16;4(4):362-73. doi: 10.1016/j.chom.2008.08.014.

13.

Aggravation of viral hepatitis by platelet-derived serotonin.

Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, Hegazy AN, Löhning M, Harris NL, Ohashi PS, Hengartner H, Zinkernagel RM, Lang KS.

Nat Med. 2008 Jul;14(7):756-61. doi: 10.1038/nm1780. Epub 2008 May 30.

PMID:
18516052
14.

Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8.

Kranich J, Krautler NJ, Heinen E, Polymenidou M, Bridel C, Schildknecht A, Huber C, Kosco-Vilbois MH, Zinkernagel R, Miele G, Aguzzi A.

J Exp Med. 2008 Jun 9;205(6):1293-302. doi: 10.1084/jem.20071019. Epub 2008 May 19.

16.

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.

Löhning M, Hegazy AN, Pinschewer DD, Busse D, Lang KS, Höfer T, Radbruch A, Zinkernagel RM, Hengartner H.

J Exp Med. 2008 Jan 21;205(1):53-61. doi: 10.1084/jem.20071855. Epub 2008 Jan 14.

17.

Long-term maternal imprinting of the specific B cell repertoire by maternal antibodies.

Fink K, Zellweger R, Weber J, Manjarrez-Orduno N, Holdener M, Senn BM, Hengartner H, Zinkernagel RM, Macpherson AJ.

Eur J Immunol. 2008 Jan;38(1):90-101.

18.

"Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses.

Lang KS, Hegazy AN, Lang PA, Eschli B, Löhning M, Hengartner H, Zinkernagel RM, Recher M.

PLoS One. 2007 Nov 14;2(11):e1162.

19.

Induced prion protein controls immune-activated retroviruses in the mouse spleen.

Lötscher M, Recher M, Lang KS, Navarini A, Hunziker L, Santimaria R, Glatzel M, Schwarz P, Böni J, Zinkernagel RM.

PLoS One. 2007 Nov 7;2(11):e1158.

20.

Extralymphatic virus sanctuaries as a consequence of potent T-cell activation.

Recher M, Lang KS, Navarini A, Hunziker L, Lang PA, Fink K, Freigang S, Georgiev P, Hangartner L, Zellweger R, Bergthaler A, Hegazy AN, Eschli B, Theocharides A, Jeker LT, Merkler D, Odermatt B, Hersberger M, Hengartner H, Zinkernagel RM.

Nat Med. 2007 Nov;13(11):1316-23. Epub 2007 Nov 4.

PMID:
17982463
21.

B cell activation state-governed formation of germinal centers following viral infection.

Fink K, Manjarrez-Orduño N, Schildknecht A, Weber J, Senn BM, Zinkernagel RM, Hengartner H.

J Immunol. 2007 Nov 1;179(9):5877-85.

22.

Early antibodies specific for the neutralizing epitope on the receptor binding subunit of the lymphocytic choriomeningitis virus glycoprotein fail to neutralize the virus.

Eschli B, Zellweger RM, Wepf A, Lang KS, Quirin K, Weber J, Zinkernagel RM, Hengartner H.

J Virol. 2007 Nov;81(21):11650-7. Epub 2007 Aug 15.

23.

A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses.

Freigang S, Eschli B, Harris N, Geuking M, Quirin K, Schrempf S, Zellweger R, Weber J, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13426-31. Epub 2007 Aug 8.

24.

MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus.

Lang KS, Navarini AA, Recher M, Lang PA, Heikenwalder M, Stecher B, Bergthaler A, Odermatt B, Akira S, Honda K, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2007 Sep;37(9):2434-40.

25.

Identification and characterization of a novel antigen from the nematode Nippostrongylus brasiliensis recognized by specific IgE.

Pochanke V, Koller S, Dayer R, Hatak S, Ludewig B, Zinkernagel RM, Hengartner H, McCoy KD.

Eur J Immunol. 2007 May;37(5):1275-84.

26.

On observing and analyzing disease versus signals.

Zinkernagel R.

Nat Immunol. 2007 Jan;8(1):8-10.

PMID:
17179962
27.

Crystal-ball gazing--the future of immunological research viewed from the cutting edge.

Brent L, Cohen IR, Doherty PC, Feldmann M, Matzinger P, Ghost Lab, Holgate ST, Lachmann P, Mitchison NA, Nossal G, Rose NR, Zinkernagel R.

Clin Exp Immunol. 2007 Jan;147(1):1-10. No abstract available.

28.

Parameters governing exhaustion of rare T cell-independent neutralizing IgM-producing B cells after LCMV infection.

Zellweger RM, Hangartner L, Weber J, Zinkernagel RM, Hengartner H.

Eur J Immunol. 2006 Dec;36(12):3175-85.

29.

Mechanisms of neonatal mucosal antibody protection.

Harris NL, Spoerri I, Schopfer JF, Nembrini C, Merky P, Massacand J, Urban JF Jr, Lamarre A, Burki K, Odermatt B, Zinkernagel RM, Macpherson AJ.

J Immunol. 2006 Nov 1;177(9):6256-62.

30.

Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses.

Navarini AA, Recher M, Lang KS, Georgiev P, Meury S, Bergthaler A, Flatz L, Bille J, Landmann R, Odermatt B, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15535-9. Epub 2006 Oct 9.

31.

Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.

Martinic MM, van den Broek MF, Rülicke T, Huber C, Odermatt B, Reith W, Horvath E, Zellweger R, Fink K, Recher M, Eschli B, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14435-40. Epub 2006 Sep 18.

32.

Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling.

Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, Harris NL, Junt T, Odermatt B, Clavien PA, Pircher H, Akira S, Hengartner H, Zinkernagel RM.

J Clin Invest. 2006 Sep;116(9):2456-63.

33.

Induction of IgE and allergic-type responses in fur mite-infested mice.

Pochanke V, Hatak S, Hengartner H, Zinkernagel RM, McCoy KD.

Eur J Immunol. 2006 Sep;36(9):2434-45.

34.

Nonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread.

Hangartner L, Zellweger RM, Giobbi M, Weber J, Eschli B, McCoy KD, Harris N, Recher M, Zinkernagel RM, Hengartner H.

J Exp Med. 2006 Aug 7;203(8):2033-42. Epub 2006 Jul 31.

35.

Expression of lymphotoxin beta governs immunity at two distinct levels.

Junt T, Tumanov AV, Harris N, Heikenwalder M, Zeller N, Kuprash DV, Aguzzi A, Ludewig B, Nedospasov SA, Zinkernagel RM.

Eur J Immunol. 2006 Aug;36(8):2061-75.

36.
37.

Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses.

Fink K, Lang KS, Manjarrez-Orduno N, Junt T, Senn BM, Holdener M, Akira S, Zinkernagel RM, Hengartner H.

Eur J Immunol. 2006 Aug;36(8):2094-105.

38.
39.

"Viral déjà vu" elicits organ-specific immune disease independent of reactivity to self.

Merkler D, Horvath E, Bruck W, Zinkernagel RM, Del la Torre JC, Pinschewer DD.

J Clin Invest. 2006 May;116(5):1254-63. Epub 2006 Apr 6.

40.

Natural IgE production in the absence of MHC Class II cognate help.

McCoy KD, Harris NL, Diener P, Hatak S, Odermatt B, Hangartner L, Senn BM, Marsland BJ, Geuking MB, Hengartner H, Macpherson AJ, Zinkernagel RM.

Immunity. 2006 Mar;24(3):329-39.

41.

Antiviral antibody responses: the two extremes of a wide spectrum.

Hangartner L, Zinkernagel RM, Hengartner H.

Nat Rev Immunol. 2006 Mar;6(3):231-43. Review.

PMID:
16498452
42.

Microchimerism maintains deletion of the donor cell-specific CD8+ T cell repertoire.

Bonilla WV, Geuking MB, Aichele P, Ludewig B, Hengartner H, Zinkernagel RM.

J Clin Invest. 2006 Jan;116(1):156-62.

43.

CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses.

Junt T, Fink K, Förster R, Senn B, Lipp M, Muramatsu M, Zinkernagel RM, Ludewig B, Hengartner H.

J Immunol. 2005 Dec 1;175(11):7109-16.

44.

Requirement for neutralizing antibodies to control bone marrow transplantation-associated persistent viral infection and to reduce immunopathology.

Lang KS, Recher M, Navarini AA, Freigang S, Harris NL, van den Broek M, Odermatt B, Hengartner H, Zinkernagel RM.

J Immunol. 2005 Oct 15;175(8):5524-31.

45.

Responses to Cohn's discussion on the Zinkernagel-Hengartner 'Credo 2004'.

Zinkernagel R, Hengartner H.

Scand J Immunol. 2005 Sep;62(3):195-201. No abstract available.

46.

Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells.

Probst HC, Tschannen K, Odermatt B, Schwendener R, Zinkernagel RM, Van Den Broek M.

Clin Exp Immunol. 2005 Sep;141(3):398-404.

47.

Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation.

Lang KS, Recher M, Navarini AA, Harris NL, Löhning M, Junt T, Probst HC, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2005 Mar;35(3):738-45.

48.

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.

Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM.

Nat Med. 2005 Feb;11(2):138-45. Epub 2005 Jan 16. Erratum in: Nat Med. 2005 Nov;11(11):1256.

PMID:
15654326
49.

Kinetics of protective antibodies are determined by the viral surface antigen.

Pinschewer DD, Perez M, Jeetendra E, Bächi T, Horvath E, Hengartner H, Whitt MA, de la Torre JC, Zinkernagel RM.

J Clin Invest. 2004 Oct;114(7):988-93.

50.

Deliberate removal of T cell help improves virus-neutralizing antibody production.

Recher M, Lang KS, Hunziker L, Freigang S, Eschli B, Harris NL, Navarini A, Senn BM, Fink K, Lötscher M, Hangartner L, Zellweger R, Hersberger M, Theocharides A, Hengartner H, Zinkernagel RM.

Nat Immunol. 2004 Sep;5(9):934-42. Epub 2004 Aug 8.

PMID:
15300247

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