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Items: 1 to 50 of 73

1.

Meloxicam increases epidermal growth factor receptor expression improving survival after hepatic resection in diet-induced obese mice.

Jin X, Zimmers TA, Jiang Y, Milgrom DP, Zhang Z, Koniaris LG.

Surgery. 2018 Feb 1. pii: S0039-6060(17)30881-4. doi: 10.1016/j.surg.2017.11.029. [Epub ahead of print]

PMID:
29361369
2.

Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naïve pancreatic cancer patients.

Talbert EE, Lewis HL, Farren MR, Ramsey ML, Chakedis JM, Rajasekera P, Haverick E, Sarna A, Bloomston M, Pawlik TM, Zimmers TA, Lesinski GB, Hart PA, Dillhoff ME, Schmidt CR, Guttridge DC.

J Cachexia Sarcopenia Muscle. 2018 Apr;9(2):358-368. doi: 10.1002/jcsm.12251. Epub 2018 Jan 7.

3.

An Assessment of the Academic Impact of Shock Society Members.

Milgrom DP, Koniaris LG, Valsangkar NP, Lad N, Bell TM, Wojcik B, Zimmers TA.

Shock. 2018 May;49(5):508-513. doi: 10.1097/SHK.0000000000001049.

PMID:
29112102
4.

Erratum to: Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting.

Zimmers TA, Jiang Y, Wang M, Liang TW, Rupert JE, Au ED, Marino FE, Couch ME, Koniaris LG.

Basic Res Cardiol. 2017 Sep;112(5):53. doi: 10.1007/s00395-017-0642-1. No abstract available.

PMID:
28721633
5.

Epidermal growth factor receptor restoration rescues the fatty liver regeneration in mice.

Zimmers TA, Jin X, Zhang Z, Jiang Y, Koniaris LG.

Am J Physiol Endocrinol Metab. 2017 Oct 1;313(4):E440-E449. doi: 10.1152/ajpendo.00032.2017. Epub 2017 Jun 27.

PMID:
28655714
6.

Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting.

Zimmers TA, Jiang Y, Wang M, Liang TW, Rupert JE, Au ED, Marino FE, Couch ME, Koniaris LG.

Basic Res Cardiol. 2017 Jul;112(4):48. doi: 10.1007/s00395-017-0639-9. Epub 2017 Jun 24. Erratum in: Basic Res Cardiol. 2017 Sep;112(5):53.

PMID:
28647906
7.

Bone Pain and Muscle Weakness in Cancer Patients.

Milgrom DP, Lad NL, Koniaris LG, Zimmers TA.

Curr Osteoporos Rep. 2017 Apr;15(2):76-87. doi: 10.1007/s11914-017-0354-3. Review.

8.

Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases.

Sato AY, Richardson D, Cregor M, Davis HM, Au ED, McAndrews K, Zimmers TA, Organ JM, Peacock M, Plotkin LI, Bellido T.

Endocrinology. 2017 Mar 1;158(3):664-677. doi: 10.1210/en.2016-1779.

9.

The MEK-Inhibitor Selumetinib Attenuates Tumor Growth and Reduces IL-6 Expression but Does Not Protect against Muscle Wasting in Lewis Lung Cancer Cachexia.

Au ED, Desai AP, Koniaris LG, Zimmers TA.

Front Physiol. 2017 Jan 18;7:682. doi: 10.3389/fphys.2016.00682. eCollection 2016.

10.

Differential Bone Loss in Mouse Models of Colon Cancer Cachexia.

Bonetto A, Kays JK, Parker VA, Matthews RR, Barreto R, Puppa MJ, Kang KS, Carson JA, Guise TA, Mohammad KS, Robling AG, Couch ME, Koniaris LG, Zimmers TA.

Front Physiol. 2017 Jan 11;7:679. doi: 10.3389/fphys.2016.00679. eCollection 2016.

11.

Endangered academia: preserving the pediatric surgeon scientist.

Markel TA, Valsangkar NP, Bell TM, Kiel BA, Zimmers TA, Koniaris LG.

J Pediatr Surg. 2017 Jul;52(7):1079-1083. doi: 10.1016/j.jpedsurg.2016.12.006. Epub 2016 Dec 20.

PMID:
28017413
12.

The Role of PhD Faculty in Advancing Research in Departments of Surgery.

Bell TM, Valsangkar N, Joshi M, Mayo J, Blanton C, Zimmers TA, Torbeck L, Koniaris LG.

Ann Surg. 2017 Jan;265(1):111-115. doi: 10.1097/SLA.0000000000001657.

13.

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia.

Bonetto A, Rupert JE, Barreto R, Zimmers TA.

J Vis Exp. 2016 Nov 30;(117). doi: 10.3791/54893.

14.

Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways.

Barreto R, Mandili G, Witzmann FA, Novelli F, Zimmers TA, Bonetto A.

Front Physiol. 2016 Oct 19;7:472. eCollection 2016.

15.

IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.

Mace TA, Shakya R, Pitarresi JR, Swanson B, McQuinn CW, Loftus S, Nordquist E, Cruz-Monserrate Z, Yu L, Young G, Zhong X, Zimmers TA, Ostrowski MC, Ludwig T, Bloomston M, Bekaii-Saab T, Lesinski GB.

Gut. 2018 Feb;67(2):320-332. doi: 10.1136/gutjnl-2016-311585. Epub 2016 Oct 21.

PMID:
27797936
16.

Impact of Integrated Vascular Residencies on Academic Productivity within Vascular Surgery Divisions.

Kim BJ, Valsangkar NP, Liang TW, Murphy MP, Zimmers TA, Bell TM, Davies MG, Koniaris LG.

Ann Vasc Surg. 2017 Feb;39:242-249. doi: 10.1016/j.avsg.2016.06.031. Epub 2016 Sep 23.

PMID:
27671458
17.

The positive association of Association for Academic Surgery membership with academic productivity.

Valsangkar NP, Milgrom DP, Martin PJ, Parett JS, Joshi MM, Zimmers TA, Koniaris LG.

J Surg Res. 2016 Sep;205(1):163-8. doi: 10.1016/j.jss.2016.06.030. Epub 2016 Jun 17.

PMID:
27621014
18.

Impact of clinical fellowships on academic productivity in departments of surgery.

Valsangkar NP, Liang TW, Martin PJ, Mayo JS, Rosati CM, Feliciano DV, Zimmers TA, Koniaris LG.

Surgery. 2016 Dec;160(6):1440-1446. doi: 10.1016/j.surg.2016.07.009. Epub 2016 Aug 11.

PMID:
27524426
19.

Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma.

Ogunbileje JO, Porter C, Herndon DN, Chao T, Abdelrahman DR, Papadimitriou A, Chondronikola M, Zimmers TA, Reidy PT, Rasmussen BB, Sidossis LS.

Am J Physiol Endocrinol Metab. 2016 Aug 1;311(2):E436-48. doi: 10.1152/ajpendo.00535.2015. Epub 2016 Jul 5.

20.

Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs.

Barreto R, Waning DL, Gao H, Liu Y, Zimmers TA, Bonetto A.

Oncotarget. 2016 Jul 12;7(28):43442-43460. doi: 10.18632/oncotarget.9779.

21.

Is there an impending loss of academically productive trauma surgical faculty? An analysis of 4,015 faculty.

Valsangkar NP, Blanton C, Mayo JS, Rozycki GS, Bell TM, Zimmers TA, Feliciano DV, Koniaris LG.

J Trauma Acute Care Surg. 2016 Aug;81(2):244-53. doi: 10.1097/TA.0000000000001117.

PMID:
27257706
22.

The impact of members of the Society of University Surgeons on the scholarship of American surgery.

Valsangkar NP, Kays JK, Feliciano DV, Martin PJ, Parett JS, Joshi MM, Zimmers TA, Koniaris LG.

Surgery. 2016 Jul;160(1):47-53. doi: 10.1016/j.surg.2016.03.016. Epub 2016 May 12.

23.

Understanding the Barriers to Hiring and Promoting Women in Surgical Subspecialties.

Valsangkar N, Fecher AM, Rozycki GS, Blanton C, Bell TM, Freischlag J, Ahuja N, Zimmers TA, Koniaris LG.

J Am Coll Surg. 2016 Aug;223(2):387-398.e2. doi: 10.1016/j.jamcollsurg.2016.03.042. Epub 2016 Apr 20.

PMID:
27109779
24.

Do Plastic Surgery Programs with Integrated Residencies or Subspecialty Fellowships Have Increased Academic Productivity?

Duquette SP, Valsangkar NP, Sood R, Socas J, Zimmers TA, Koniaris LG.

Plast Reconstr Surg Glob Open. 2016 Feb 10;4(2):e614. doi: 10.1097/GOX.0000000000000596. eCollection 2016 Feb.

25.

STAT3 in the systemic inflammation of cancer cachexia.

Zimmers TA, Fishel ML, Bonetto A.

Semin Cell Dev Biol. 2016 Jun;54:28-41. doi: 10.1016/j.semcdb.2016.02.009. Epub 2016 Feb 6. Review.

26.

Current management of gastrointestinal stromal tumors: Surgery, current biomarkers, mutations, and therapy.

Valsangkar N, Sehdev A, Misra S, Zimmers TA, O'Neil BH, Koniaris LG.

Surgery. 2015 Nov;158(5):1149-64. doi: 10.1016/j.surg.2015.06.027. Epub 2015 Aug 1. Review.

PMID:
26243346
27.

Protecting Ideas: Ethical and Legal Considerations When a Grant's Principal Investigator Changes.

Koniaris LG, Coombs MI, Meslin EM, Zimmers TA.

Sci Eng Ethics. 2016 Aug;22(4):1051-1061. doi: 10.1007/s11948-015-9688-3. Epub 2015 Jul 31. Review.

28.

Determining the Drivers of Academic Success in Surgery: An Analysis of 3,850 Faculty.

Valsangkar NP, Zimmers TA, Kim BJ, Blanton C, Joshi MM, Bell TM, Nakeeb A, Dunnington GL, Koniaris LG.

PLoS One. 2015 Jul 15;10(7):e0131678. doi: 10.1371/journal.pone.0131678. eCollection 2015.

29.

Electronic medical record: a balancing act of patient safety, privacy and health care delivery.

Gummadi S, Housri N, Zimmers TA, Koniaris LG.

Am J Med Sci. 2014 Sep;348(3):238-43. doi: 10.1097/MAJ.0000000000000287. Review.

PMID:
24879530
30.

Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.

Yoshimatsu Y, Lee YG, Akatsu Y, Taguchi L, Suzuki HI, Cunha SI, Maruyama K, Suzuki Y, Yamazaki T, Katsura A, Oh SP, Zimmers TA, Lee SJ, Pietras K, Koh GY, Miyazono K, Watabe T.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18940-5. doi: 10.1073/pnas.1310479110. Epub 2013 Oct 16.

31.

Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation.

Levet S, Ciais D, Merdzhanova G, Mallet C, Zimmers TA, Lee SJ, Navarro FP, Texier I, Feige JJ, Bailly S, Vittet D.

Blood. 2013 Jul 25;122(4):598-607. doi: 10.1182/blood-2012-12-472142. Epub 2013 Jun 5.

32.

Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.

Guido C, Whitaker-Menezes D, Lin Z, Pestell RG, Howell A, Zimmers TA, Casimiro MC, Aquila S, Ando' S, Martinez-Outschoorn UE, Sotgia F, Lisanti MP.

Oncotarget. 2012 Aug;3(8):798-810.

33.

Hedgehog signaling regulates bladder cancer growth and tumorigenicity.

Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, Bejarano P, Capobianco AJ, Robbins DJ.

Cancer Res. 2012 Sep 1;72(17):4449-58. Epub 2012 Jul 19.

34.

JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia.

Bonetto A, Aydogdu T, Jin X, Zhang Z, Zhan R, Puzis L, Koniaris LG, Zimmers TA.

Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E410-21. doi: 10.1152/ajpendo.00039.2012. Epub 2012 Jun 5.

35.

BMP9 and BMP10 are critical for postnatal retinal vascular remodeling.

Ricard N, Ciais D, Levet S, Subileau M, Mallet C, Zimmers TA, Lee SJ, Bidart M, Feige JJ, Bailly S.

Blood. 2012 Jun 21;119(25):6162-71. doi: 10.1182/blood-2012-01-407593. Epub 2012 May 7.

36.

The influence of Hispanic ethnicity on nonsmall cell lung cancer histology and patient survival: an analysis of the Survival, Epidemiology, and End Results database.

Saeed AM, Toonkel R, Glassberg MK, Nguyen D, Hu JJ, Zimmers TA, Robbins DJ, Koniaris LG, Lally BE.

Cancer. 2012 Sep 15;118(18):4495-501. doi: 10.1002/cncr.26686. Epub 2012 Apr 23.

37.

Inflammation, organomegaly, and muscle wasting despite hyperphagia in a mouse model of burn cachexia.

Pedroso FE, Spalding PB, Cheung MC, Yang R, Gutierrez JC, Bonetto A, Zhan R, Chan HL, Namias N, Koniaris LG, Zimmers TA.

J Cachexia Sarcopenia Muscle. 2012 Sep;3(3):199-211. doi: 10.1007/s13539-012-0062-x. Epub 2012 Mar 29.

38.

Increase in muscle mitochondrial biogenesis does not prevent muscle loss but increased tumor size in a mouse model of acute cancer-induced cachexia.

Wang X, Pickrell AM, Zimmers TA, Moraes CT.

PLoS One. 2012;7(3):e33426. doi: 10.1371/journal.pone.0033426. Epub 2012 Mar 12.

39.

Is surgical resection superior to transplantation in the treatment of hepatocellular carcinoma?

Koniaris LG, Levi DM, Pedroso FE, Franceschi D, Tzakis AG, Santamaria-Barria JA, Tang J, Anderson M, Misra S, Solomon NL, Jin X, DiPasco PJ, Byrne MM, Zimmers TA.

Ann Surg. 2011 Sep;254(3):527-37; discussion 537-8. doi: 10.1097/SLA.0b013e31822ca66f.

40.

STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia.

Bonetto A, Aydogdu T, Kunzevitzky N, Guttridge DC, Khuri S, Koniaris LG, Zimmers TA.

PLoS One. 2011;6(7):e22538. doi: 10.1371/journal.pone.0022538. Epub 2011 Jul 20.

41.

Obesity and weight loss at presentation of lung cancer are associated with opposite effects on survival.

Yang R, Cheung MC, Pedroso FE, Byrne MM, Koniaris LG, Zimmers TA.

J Surg Res. 2011 Sep;170(1):e75-83. doi: 10.1016/j.jss.2011.04.061. Epub 2011 May 23.

42.

Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse.

Clementi AH, Gaudy AM, Zimmers TA, Koniaris LG, Mooney RA.

Metabolism. 2011 Nov;60(11):1610-9. doi: 10.1016/j.metabol.2011.04.004. Epub 2011 May 31.

43.

Regulation of muscle mass by follistatin and activins.

Lee SJ, Lee YS, Zimmers TA, Soleimani A, Matzuk MM, Tsuchida K, Cohn RD, Barton ER.

Mol Endocrinol. 2010 Oct;24(10):1998-2008. doi: 10.1210/me.2010-0127. Epub 2010 Sep 1.

44.

Leveraging combinatorial chemotherapy to improve outcomes in patients with pancreatic cancer.

Koniaris LG, Jin X, Montero AJ, Zimmers TA.

Cancer Biol Ther. 2010 Jul 1;10(1):108-9. Epub 2010 Jul 21. No abstract available.

PMID:
20581450
45.

Perspective: PhD scientists completing medical school in two years: looking at the Miami PhD-to-MD program alumni twenty years later.

Koniaris LG, Cheung MC, Garrison G, Awad WM Jr, Zimmers TA.

Acad Med. 2010 Apr;85(4):687-91. doi: 10.1097/ACM.0b013e3181d296da.

PMID:
20354390
46.

Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia.

Benny Klimek ME, Aydogdu T, Link MJ, Pons M, Koniaris LG, Zimmers TA.

Biochem Biophys Res Commun. 2010 Jan 15;391(3):1548-54. doi: 10.1016/j.bbrc.2009.12.123. Epub 2009 Dec 28.

PMID:
20036643
47.

Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer.

Zimmers TA, Gutierrez JC, Koniaris LG.

J Cancer Res Clin Oncol. 2010 Apr;136(4):571-6. doi: 10.1007/s00432-009-0691-4. Epub 2009 Sep 27.

PMID:
19784846
48.

A comprehensive evaluation of outcomes for inflammatory breast cancer.

Yang R, Cheung MC, Hurley J, Byrne MM, Huang Y, Zimmers TA, Koniaris LG.

Breast Cancer Res Treat. 2009 Oct;117(3):631-41. doi: 10.1007/s10549-009-0312-6. Epub 2009 Jan 24.

PMID:
19169811
49.

Interleukin-6 is an important in vivo inhibitor of intestinal epithelial cell death in mice.

Jin X, Zimmers TA, Zhang Z, Pierce RH, Koniaris LG.

Gut. 2010 Feb;59(2):186-96. doi: 10.1136/gut.2008.151175. Epub 2008 Dec 11.

PMID:
19074180
50.

Body surface area prediction in normal, hypermuscular, and obese mice.

Cheung MC, Spalding PB, Gutierrez JC, Balkan W, Namias N, Koniaris LG, Zimmers TA.

J Surg Res. 2009 May 15;153(2):326-31. doi: 10.1016/j.jss.2008.05.002. Epub 2008 Jun 4.

PMID:
18952236

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