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Referred cramping phantom hand pain elicited in the face and eliminated by peripheral nerve block.

Dietrich C, Nehrdich S, Zimmer A, Ritter A, Hofmann GO, Miltner WHR, Weiss T.

Exp Brain Res. 2018 Apr 17. doi: 10.1007/s00221-018-5262-y. [Epub ahead of print]


A machine learning model to determine the accuracy of variant calls in capture-based next generation sequencing.

van den Akker J, Mishne G, Zimmer AD, Zhou AY.

BMC Genomics. 2018 Apr 17;19(1):263. doi: 10.1186/s12864-018-4659-0.


Update on PARP Inhibitors in Breast Cancer.

Zimmer AS, Gillard M, Lipkowitz S, Lee JM.

Curr Treat Options Oncol. 2018 Apr 11;19(5):21. doi: 10.1007/s11864-018-0540-2. Review.


SERCA plays a crucial role in the toxicity of a betulinic acid derivative with potential antimalarial activity.

Diedrich D, Wildner AC, Silveira TF, Silva GNS, Santos FD, da Silva EF, do Canto VP, Visioli F, Gosmann G, Bergold AM, Zimmer AR, Netz PA, Gnoatto SCB.

Chem Biol Interact. 2018 Mar 28;287:70-77. doi: 10.1016/j.cbi.2018.03.014. [Epub ahead of print]


The loss of SMG1 causes defects in quality control pathways in Physcomitrella patens.

Lloyd JPB, Lang D, Zimmer AD, Causier B, Reski R, Davies B.

Nucleic Acids Res. 2018 Mar 27. doi: 10.1093/nar/gky225. [Epub ahead of print]


Influence of cell type and cell culture media on the propagation of foot-and-mouth disease virus with regard to vaccine quality.

Dill V, Hoffmann B, Zimmer A, Beer M, Eschbaumer M.

Virol J. 2018 Mar 16;15(1):46. doi: 10.1186/s12985-018-0956-0.


Exercise training versus T3 and T4 hormones treatment: The differential benefits of thyroid hormones on the parasympathetic drive of infarcted rats.

Teixeira RB, Zimmer A, de Castro AL, Carraro CC, Casali KR, Dias IGM, Godoy AEG, Litvin IE, Belló-Klein A, da Rosa Araujo AS.

Life Sci. 2018 Mar 1;196:93-101. doi: 10.1016/j.lfs.2018.01.018. Epub 2018 Feb 3.


Prexasertib, a cell cycle checkpoint kinase 1 and 2 inhibitor, in BRCA wild-type recurrent high-grade serous ovarian cancer: a first-in-class proof-of-concept phase 2 study.

Lee JM, Nair J, Zimmer A, Lipkowitz S, Annunziata CM, Merino MJ, Swisher EM, Harrell MI, Trepel JB, Lee MJ, Bagheri MH, Botesteanu DA, Steinberg SM, Minasian L, Ekwede I, Kohn EC.

Lancet Oncol. 2018 Feb;19(2):207-215. doi: 10.1016/S1470-2045(18)30009-3. Epub 2018 Jan 18.


Analysis of breast cancer in young women in the Department of Defense (DOD) database.

Zimmer AS, Zhu K, Steeg PS, Wu A, Gatti-Mays ME, Soltani S, Perkins JG, Shao S, Brown D, Georg M, Hu H, Shriver CD, Lipkowitz S.

Breast Cancer Res Treat. 2018 Apr;168(2):501-511. doi: 10.1007/s10549-017-4615-8. Epub 2017 Dec 15.


The Position of Targeted Next-generation Sequencing in Epidermolysis Bullosa Diagnosis.

Has C, Küsel J, Reimer A, Hoffmann J, Schauer F, Zimmer A, Fischer J.

Acta Derm Venereol. 2018 Apr 16;98(4):437-440. doi: 10.2340/00015555-2863.


The Physcomitrella patens chromosome-scale assembly reveals moss genome structure and evolution.

Lang D, Ullrich KK, Murat F, Fuchs J, Jenkins J, Haas FB, Piednoel M, Gundlach H, Van Bel M, Meyberg R, Vives C, Morata J, Symeonidi A, Hiss M, Muchero W, Kamisugi Y, Saleh O, Blanc G, Decker EL, van Gessel N, Grimwood J, Hayes RD, Graham SW, Gunter LE, McDaniel SF, Hoernstein SNW, Larsson A, Li FW, Perroud PF, Phillips J, Ranjan P, Rokshar DS, Rothfels CJ, Schneider L, Shu S, Stevenson DW, Thümmler F, Tillich M, Villarreal Aguilar JC, Widiez T, Wong GK, Wymore A, Zhang Y, Zimmer AD, Quatrano RS, Mayer KFX, Goodstein D, Casacuberta JM, Vandepoele K, Reski R, Cuming AC, Tuskan GA, Maumus F, Salse J, Schmutz J, Rensing SA.

Plant J. 2018 Feb;93(3):515-533. doi: 10.1111/tpj.13801.


Performance indicators for carrier-based DPIs: Carrier surface properties for capsule filling and API properties for in vitro aerosolisation.

Faulhammer E, Zellnitz S, Wutscher T, Stranzinger S, Zimmer A, Paudel A.

Int J Pharm. 2018 Jan 30;536(1):326-335. doi: 10.1016/j.ijpharm.2017.12.004. Epub 2017 Dec 5.


Adherence to fingolimod in multiple sclerosis: an investigator-initiated, prospective, observational, single-center cohort study.

Zimmer A, Coslovsky M, Abraham I, Décard BF.

Patient Prefer Adherence. 2017 Oct 20;11:1815-1830. doi: 10.2147/PPA.S140293. eCollection 2017.


Dynamic Proteomics of Herpes Simplex Virus Infection.

Drayman N, Karin O, Mayo A, Danon T, Shapira L, Rafael D, Zimmer A, Bren A, Kobiler O, Alon U.

MBio. 2017 Nov 7;8(6). pii: e01612-17. doi: 10.1128/mBio.01612-17.


Ammonia and urea handling by early life stages of fishes.

Zimmer AM, Wright PA, Wood CM.

J Exp Biol. 2017 Nov 1;220(Pt 21):3843-3855. doi: 10.1242/jeb.140210. Review.


Prediction of drug cocktail effects when the number of measurements is limited.

Zimmer A, Tendler A, Katzir I, Mayo A, Alon U.

PLoS Biol. 2017 Oct 26;15(10):e2002518. doi: 10.1371/journal.pbio.2002518. eCollection 2017 Oct.


Solvent Vapor Annealing of Amorphous Carbamazepine Films for Fast Polymorph Screening and Dissolution Alteration.

Schrode B, Bodak B, Riegler H, Zimmer A, Christian P, Werzer O.

ACS Omega. 2017 Sep 30;2(9):5582-5590. doi: 10.1021/acsomega.7b00783. Epub 2017 Sep 7.


Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Fuchs H, Aguilar-Pimentel JA, Amarie OV, Becker L, Calzada-Wack J, Cho YL, Garrett L, Hölter SM, Irmler M, Kistler M, Kraiger M, Mayer-Kuckuk P, Moreth K, Rathkolb B, Rozman J, da Silva Buttkus P, Treise I, Zimprich A, Gampe K, Hutterer C, Stöger C, Leuchtenberger S, Maier H, Miller M, Scheideler A, Wu M, Beckers J, Bekeredjian R, Brielmeier M, Busch DH, Klingenspor M, Klopstock T, Ollert M, Schmidt-Weber C, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Gailus-Durner V, Hrabě de Angelis M.

Behav Brain Res. 2017 Sep 29. pii: S0166-4328(17)30931-2. doi: 10.1016/j.bbr.2017.09.048. [Epub ahead of print] Review.


Quinalizarin inhibits adipogenesis through down-regulation of transcription factors and microRNA modulation.

Schwind L, Nalbach L, Zimmer AD, Kostelnik KB, Menegatti J, Grässer F, Götz C, Montenarh M.

Biochim Biophys Acta. 2017 Dec;1861(12):3272-3281. doi: 10.1016/j.bbagen.2017.09.018. Epub 2017 Sep 28.


People, planet and profit: Unintended consequences of legacy building materials.

Zimmer AT, Ha H.

J Environ Manage. 2017 Dec 15;204(Pt 1):472-485. doi: 10.1016/j.jenvman.2017.09.026. Review.


Long-term T3 and T4 treatment as an alternative to aerobic exercise training in improving cardiac function post-myocardial infarction.

Teixeira RB, Zimmer A, de Castro AL, de Lima-Seolin BG, Türck P, Siqueira R, Belló-Klein A, Singal PK, da Rosa Araujo AS.

Biomed Pharmacother. 2017 Nov;95:965-973. doi: 10.1016/j.biopha.2017.09.021. Epub 2017 Sep 11.


Combined effect of the Saccharomyces cerevisiae lag phase and the non-Saccharomyces consortium to enhance wine fruitiness and complexity.

Albertin W, Zimmer A, Miot-Sertier C, Bernard M, Coulon J, Moine V, Colonna-Ceccaldi B, Bely M, Marullo P, Masneuf-Pomarede I.

Appl Microbiol Biotechnol. 2017 Oct;101(20):7603-7620. doi: 10.1007/s00253-017-8492-1. Epub 2017 Sep 14.


Identification of mutations in SDR9C7 in six families with autosomal recessive congenital ichthyosis.

Hotz A, Fagerberg C, Vahlquist A, Bygum A, Törmä H, Rauschendorf MA, Zhang H, Heinz L, Bourrat E, Hausser I, Vestergaard V, Dragomir A, Zimmer AD, Fischer J.

Br J Dermatol. 2018 Mar;178(3):e207-e209. doi: 10.1111/bjd.15994. Epub 2018 Jan 21. No abstract available.


Developmental programming of somatic growth, behavior and endocannabinoid metabolism by variation of early postnatal nutrition in a cross-fostering mouse model.

Schreiner F, Ackermann M, Michalik M, Hucklenbruch-Rother E, Bilkei-Gorzo A, Racz I, Bindila L, Lutz B, Dötsch J, Zimmer A, Woelfle J.

PLoS One. 2017 Aug 31;12(8):e0182754. doi: 10.1371/journal.pone.0182754. eCollection 2017.


Designing optimal formulations for hot-melt coating.

Lopes DG, Salar-Behzadi S, Zimmer A.

Int J Pharm. 2017 Nov 30;533(2):357-363. doi: 10.1016/j.ijpharm.2017.08.086. Epub 2017 Aug 24.


Adaption of FMDV Asia-1 to Suspension Culture: Cell Resistance Is Overcome by Virus Capsid Alterations.

Dill V, Hoffmann B, Zimmer A, Beer M, Eschbaumer M.

Viruses. 2017 Aug 18;9(8). pii: E231. doi: 10.3390/v9080231.


Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

Xie K, Neff F, Markert A, Rozman J, Aguilar-Pimentel JA, Amarie OV, Becker L, Brommage R, Garrett L, Henzel KS, Hölter SM, Janik D, Lehmann I, Moreth K, Pearson BL, Racz I, Rathkolb B, Ryan DP, Schröder S, Treise I, Bekeredjian R, Busch DH, Graw J, Ehninger G, Klingenspor M, Klopstock T, Ollert M, Sandholzer M, Schmidt-Weber C, Weiergräber M, Wolf E, Wurst W, Zimmer A, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Ehninger D.

Nat Commun. 2017 Jul 24;8(1):155. doi: 10.1038/s41467-017-00178-3.


Fgf9 Y162C Mutation Alters Information Processing and Social Memory in Mice.

Garrett L, Becker L, Rozman J, Puk O, Stoeger T, Yildirim AÖ, Bohla A, Eickelberg O, Hans W, Prehn C, Adamski J, Klopstock T, Rácz I, Zimmer A, Klingenspor M, Fuchs H, Gailus-Durner V, Wurst W, Hrabě de Angelis M, Graw J, Hölter SM.

Mol Neurobiol. 2017 Jul 10. doi: 10.1007/s12035-017-0659-3. [Epub ahead of print]


Meis1: effects on motor phenotypes and the sensorimotor system in mice.

Salminen AV, Garrett L, Schormair B, Rozman J, Giesert F, Niedermeier KM, Becker L, Rathkolb B, Rácz I; German Mouse Clinic Consortium, Klingenspor M, Klopstock T, Wolf E, Zimmer A, Gailus-Durner V, Torres M, Fuchs H, Hrabě de Angelis M, Wurst W, Hölter SM, Winkelmann J.

Dis Model Mech. 2017 Aug 1;10(8):981-991. doi: 10.1242/dmm.030080. Epub 2017 Jun 23.


Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease.

Ruland C, Renken H, Kuzmanov I, Fattahi Mehr A, Schwarte K, Cerina M, Herrmann A, Otte DM, Zimmer A, Schwab N, Meuth SG, Arolt V, Klotz L, Förster I, Scheu S, Alferink J.

Brain Behav Immun. 2017 Nov;66:382-393. doi: 10.1016/j.bbi.2017.06.010. Epub 2017 Jun 19.


Tick, Diseases, Babesiosis.

Zimmer AJ, Simonsen KA.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-.
2017 Feb 7.


ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.

Cesi G, Walbrecq G, Zimmer A, Kreis S, Haan C.

Mol Cancer. 2017 Jun 8;16(1):102. doi: 10.1186/s12943-017-0667-y.


Impact of S-sulfocysteine on fragments and trisulfide bond linkages in monoclonal antibodies.

Seibel R, Maier S, Schnellbaecher A, Bohl S, Wehsling M, Zeck A, Zimmer A.

MAbs. 2017 Aug/Sep;9(6):889-897. doi: 10.1080/19420862.2017.1333212. Epub 2017 Jun 5.


Mutations in SULT2B1 Cause Autosomal-Recessive Congenital Ichthyosis in Humans.

Heinz L, Kim GJ, Marrakchi S, Christiansen J, Turki H, Rauschendorf MA, Lathrop M, Hausser I, Zimmer AD, Fischer J.

Am J Hum Genet. 2017 Jun 1;100(6):926-939. doi: 10.1016/j.ajhg.2017.05.007.


Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

van den Bruck R, Weil PP, Ziegenhals T, Schreiner P, Juranek S, Gödde D, Vogel S, Schuster F, Orth V, Dörner J, Pembaur D, Röper M, Störkel S, Zirngibl H, Wirth S, Jenke ACW, Postberg J, Boy N, Heringer J, Haege G, Glahn EM, Hoffmann GF, Garbade SF, Burgard P, Kölker S, Chao CM, Yahya F, Moiseenko A, Shrestha A, Ahmadvand N, Quantius J, Wilhelm J, El-Agha E, Zimmer KP, Bellusci S, Staufner C, Kölker S, Prokisch H, Hoffmann GF, Seeliger S, Müller M, Hippe A, Steinkraus H, Wauer R, Lachmann B, Hofmann SR, Hedrich CM, Zierk J, Arzideh F, Haeckel R, Rascher W, Rauh M, Metzler M, Thieme S, Bandoła J, Richter C, Ryser M, Jamal A, Ashton MP, von Bonin M, Kuhn M, Hedrich CM, Bonifacio E, Berner R, Brenner S, Hammersen J, Has C, Naumann-Bartsch N, Stachel D, Kiritsi D, Söder S, Tardieu M, Metzler M, Bruckner-Tuderman L, Schneider H, Bohne F, Langer D, Cencic R, Eggermann T, Zechner U, Pelletier J, Zepp F, Enklaar T, Prawitt D, Pech M, Weckmann M, Heinsen FA, Franke A, Happle C, Dittrich AM, Hansen G, Fuchs O, von Mutius E, Oliver BG, Kopp MV, Paret C, Russo A, Theruvath J, Keller B, El Malki K, Lehmann N, Wingerter A, Neu MA, Aslihan GA, Wagner W, Sommer C, Pietsch T, Seidmann L, Faber J, Schreiner F, Ackermann M, Michalik M, Rother E, Bilkei-Gorzo A, Racz I, Bindila L, Lutz B, Dötsch J, Zimmer A, Woelfle J, Fischer HS, Ullrich TL, Bührer C, Czernik C, Schmalisch G, Stein R, Hofmann SR, Hagenbuchner J, Kiechl-Kohlendorfer U, Obexer P, Ausserlechner MJ, Loges NT, Frommer AT, Wallmeier J, Omran H, Öner-Sieben S, Gimpfl M, Rozman J, Irmler M, Beckers J, De Angelis MH, Roscher A, Wolf E, Ensenauer R, Nemes K, Frühwald M, Hasselblatt M, Siebert R, Kordes U, Kool M, Wang H, Hardy H, Refai O, Barwick KES, Zimmerman HH, Weis J, Baple EL, Crosby AH, Cirak S, Hellmuth C, Uhl O, Standl M, Heinrich J, Thiering E, Koletzko B, Blümel L, Kerl K, Picard D, Frühwald MC, Liebau MC, Reifenberger G, Borkhardt A, Hasselblatt M, Remke M, Tews D, Wabitsch M, Fischer-Posovszky P, Westhoff MA, Nonnenmacher L, Langhans J, Schneele L, Trenkler N, Debatin KM.

Mol Cell Pediatr. 2017 May;4(Suppl 1):5. doi: 10.1186/s40348-017-0071-0. No abstract available.


Concordance validity of PVTs in a sample of veterans referred for mild TBI.

Zimmer A, Heyanka D, Proctor-Weber Z.

Appl Neuropsychol Adult. 2017 May 10:1-10. doi: 10.1080/23279095.2017.1319835. [Epub ahead of print]


A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice.

Bilkei-Gorzo A, Albayram O, Draffehn A, Michel K, Piyanova A, Oppenheimer H, Dvir-Ginzberg M, Rácz I, Ulas T, Imbeault S, Bab I, Schultze JL, Zimmer A.

Nat Med. 2017 Jun;23(6):782-787. doi: 10.1038/nm.4311. Epub 2017 May 8.


Safety and Clinical Activity of the Programmed Death-Ligand 1 Inhibitor Durvalumab in Combination With Poly (ADP-Ribose) Polymerase Inhibitor Olaparib or Vascular Endothelial Growth Factor Receptor 1-3 Inhibitor Cediranib in Women's Cancers: A Dose-Escalation, Phase I Study.

Lee JM, Cimino-Mathews A, Peer CJ, Zimmer A, Lipkowitz S, Annunziata CM, Cao L, Harrell MI, Swisher EM, Houston N, Botesteanu DA, Taube JM, Thompson E, Ogurtsova A, Xu H, Nguyen J, Ho TW, Figg WD, Kohn EC.

J Clin Oncol. 2017 Jul 1;35(19):2193-2202. doi: 10.1200/JCO.2016.72.1340. Epub 2017 May 4.


Design, Synthesis and Biological Evaluation of Betulinic Acid Derivatives as New Antitumor Agents for Leukemia.

Waechter F, da Silva GNS, Willig JB, de Oliveira CB, Vieira BD, Trivella DBB, Zimmer AR, Buffon A, Pilger DA, Gnoatto SCB.

Anticancer Agents Med Chem. 2017;17(13):1777-1785. doi: 10.2174/1871521409666170412143638.


Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.

Vujic N, Korbelius M, Leopold C, Duta-Mare M, Rainer S, Schlager S, Goeritzer M, Kolb D, Eichmann TO, Diwoky C, Zimmer A, Zimmermann R, Lass A, Radovic B, Kratky D.

Oncotarget. 2017 May 16;8(20):33122-33136. doi: 10.18632/oncotarget.16529.


A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.

Ryan DP, Henzel KS, Pearson BL, Siwek ME, Papazoglou A, Guo L, Paesler K, Yu M, Müller R, Xie K, Schröder S, Becker L, Garrett L, Hölter SM, Neff F, Rácz I, Rathkolb B, Rozman J, Ehninger G, Klingenspor M, Klopstock T, Wolf E, Wurst W, Zimmer A, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Sidiropoulou K, Weiergräber M, Zhou Y, Ehninger D.

Mol Psychiatry. 2017 Apr 4. doi: 10.1038/mp.2017.53. [Epub ahead of print]


Dynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitor.

Zimmer A, Amar-Farkash S, Danon T, Alon U.

BMC Syst Biol. 2017 Mar 7;11(1):33. doi: 10.1186/s12918-017-0410-8.


Antioxidant effect of thiazolidine molecules in cell culture media improves stability and performance.

Kuschelewski J, Schnellbaecher A, Pering S, Wehsling M, Zimmer A.

Biotechnol Prog. 2017 May;33(3):759-770. doi: 10.1002/btpr.2458. Epub 2017 Mar 23.


The Effects of Acute Copper and Ammonia Challenges on Ammonia and Urea Excretion by the Blue Crab Callinectes sapidus.

Zimmer AM, Jorge MB, Wood CM, Martins CM, Bianchini A.

Arch Environ Contam Toxicol. 2017 Apr;72(3):461-470. doi: 10.1007/s00244-017-0379-8. Epub 2017 Mar 4.


[Side effects of pain therapy : Sufficient analgesia without unnecessary complications].

Greul F, Zimmer A, Meißner W.

Urologe A. 2017 Apr;56(4):480-485. doi: 10.1007/s00120-017-0337-0. German.


Effects of aerobic exercise training on metabolism of nitric oxide and endothelin-1 in lung parenchyma of rats with pulmonary arterial hypertension.

Zimmer A, Teixeira RB, Bonetto JH, Siqueira R, Carraro CC, Donatti LM, Hickmann A, Litvin IE, Godoy AE, Araujo AS, Colombo R, Belló-Klein A.

Mol Cell Biochem. 2017 May;429(1-2):73-89. doi: 10.1007/s11010-016-2937-1. Epub 2017 Feb 8.


Vaccinium virgatum fruit extract as an important adjuvant in biochemical and behavioral alterations observed in animal model of metabolic syndrome.

Oliveira PS, Gazal M, Flores NP, Zimmer AR, Chaves VC, Reginatto FH, Kaster MP, Tavares RG, Spanevello RM, Lencina CL, Stefanello FM.

Biomed Pharmacother. 2017 Apr;88:939-947. doi: 10.1016/j.biopha.2017.01.121. Epub 2017 Feb 6.


Double-Strand DNA Breaks Induced by Paracyclophane Gold(I) Complexes.

Bestgen S, Seidl C, Wiesner T, Zimmer A, Falk M, Köberle B, Austeri M, Paradies J, Bräse S, Schepers U, Roesky PW.

Chemistry. 2017 May 5;23(26):6315-6322. doi: 10.1002/chem.201605237. Epub 2017 Mar 20.


Sixteen novel mutations in PNPLA1 in patients with autosomal recessive congenital ichthyosis reveal the importance of an extended patatin domain in PNPLA1 that is essential for proper human skin barrier function.

Zimmer AD, Kim GJ, Hotz A, Bourrat E, Hausser I, Has C, Oji V, Stieler K, Vahlquist A, Kunde V, Weber B, Radner FPW, Leclerc-Mercier S, Schlipf N, Demmer P, Küsel J, Fischer J.

Br J Dermatol. 2017 Aug;177(2):445-455. doi: 10.1111/bjd.15308. Epub 2017 Apr 28. Erratum in: Br J Dermatol. 2018 Mar;178(3):814-815.


Microphase separation in solid lipid dosage forms as the cause of drug release instability.

Lopes DG, Koutsamanis I, Becker K, Scheibelhofer O, Laggner P, Haack D, Stehr M, Zimmer A, Salar-Behzadi S.

Int J Pharm. 2017 Jan 30;517(1-2):403-412. doi: 10.1016/j.ijpharm.2016.12.040. Epub 2016 Dec 19.


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