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Items: 42


Targeted Doxorubicin-loaded Bacterially Derived Nano-cells for the Treatment of Neuroblastoma.

Sagnella SM, Trieu J, Brahmbhatt H, MacDiarmid JA, MacMillan A, Whan RM, Fife CM, McCarroll JA, Gifford AJM, Ziegler DS, Kavallaris M.

Mol Cancer Ther. 2018 Feb 28. pii: molcanther.0738.2017. doi: 10.1158/1535-7163.MCT-17-0738. [Epub ahead of print]


Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma.

Tsoli M, Liu J, Franshaw L, Shen H, Cheng C, Jung M, Joshi S, Ehteda A, Khan A, Montero-Carcabosso A, Dilda PJ, Hogg P, Ziegler DS.

Oncotarget. 2018 Jan 8;9(7):7541-7556. doi: 10.18632/oncotarget.24045. eCollection 2018 Jan 26.


Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group.

Bhojwani D, Burke MJ, Horton T, Ziegler DS, Sulis ML, Schultz KR, Wayne A, Izraeli S, Chang BH.

Pediatr Hematol Oncol. 2017 Sep - Oct;34(6-7):355-364. doi: 10.1080/08880018.2017.1395937. Epub 2017 Nov 30.


Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics.

Greiner R, Ziegler DS, Cibu D, Jakowetz AC, Auras F, Bein T, Knochel P.

Org Lett. 2017 Dec 1;19(23):6384-6387. doi: 10.1021/acs.orglett.7b03242. Epub 2017 Nov 20.


Comprehensive Analysis of Hypermutation in Human Cancer.

Campbell BB, Light N, Fabrizio D, Zatzman M, Fuligni F, de Borja R, Davidson S, Edwards M, Elvin JA, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Wimmer K, Kratz CP, Bowers DC, Laetsch TW, Dunn GP, Johanns TM, Grimmer MR, Smirnov IV, Larouche V, Samuel D, Bronsema A, Osborn M, Stearns D, Raman P, Cole KA, Storm PB, Yalon M, Opocher E, Mason G, Thomas GA, Sabel M, George B, Ziegler DS, Lindhorst S, Issai VM, Constantini S, Toledano H, Elhasid R, Farah R, Dvir R, Dirks P, Huang A, Galati MA, Chung J, Ramaswamy V, Irwin MS, Aronson M, Durno C, Taylor MD, Rechavi G, Maris JM, Bouffet E, Hawkins C, Costello JF, Meyn MS, Pursell ZF, Malkin D, Tabori U, Shlien A.

Cell. 2017 Nov 16;171(5):1042-1056.e10. doi: 10.1016/j.cell.2017.09.048. Epub 2017 Oct 19.


Directed Zincation or Magnesiation of the 2-Pyridone and 2,7-Naphthyridone Scaffold Using TMP Bases.

Ziegler DS, Greiner R, Lumpe H, Kqiku L, Karaghiosoff K, Knochel P.

Org Lett. 2017 Nov 3;19(21):5760-5763. doi: 10.1021/acs.orglett.7b02690.


A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH.

Sadras T, Heatley SL, Kok CH, McClure BJ, Yeung D, Hughes TP, Sutton R, Ziegler DS, White DL.

Cancer Genet. 2017 Oct;216-217:86-90. doi: 10.1016/j.cancergen.2017.07.008. Epub 2017 Jul 31.


Genomic Insights into Diffuse Intrinsic Pontine Glioma.

Lapin DH, Tsoli M, Ziegler DS.

Front Oncol. 2017 Mar 28;7:57. doi: 10.3389/fonc.2017.00057. eCollection 2017. Review.


Ganglioglioma Arising From Desmoplastic Medulloblastoma: A Case Report and Review of Literature.

Valvi S, Ziegler DS.

Pediatrics. 2017 Mar;139(3). pii: e20161403. doi: 10.1542/peds.2016-1403. Review.


The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease.

Baugh J, Bartels U, Leach J, Jones B, Chaney B, Warren KE, Kirkendall J, Doughman R, Hawkins C, Miles L, Fuller C, Hassall T, Bouffet E, Lane A, Hargrave D, Grill J, Hoffman LM, Jones C, Towbin A, Savage SA, Monje M, Li XN, Ziegler DS, Veldhuijzen van Zanten S, Kramm CM, van Vuurden DG, Fouladi M.

J Neurooncol. 2017 Apr;132(2):323-331. doi: 10.1007/s11060-017-2372-5. Epub 2017 Jan 16.


Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models.

Hennika T, Hu G, Olaciregui NG, Barton KL, Ehteda A, Chitranjan A, Chang C, Gifford AJ, Tsoli M, Ziegler DS, Carcaboso AM, Becher OJ.

PLoS One. 2017 Jan 4;12(1):e0169485. doi: 10.1371/journal.pone.0169485. eCollection 2017.


The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs.

Liu PY, Sokolowski N, Guo ST, Siddiqi F, Atmadibrata B, Telfer TJ, Sun Y, Zhang L, Yu D, Mccarroll J, Liu B, Yang RH, Guo XY, Tee AE, Itoh K, Wang J, Kavallaris M, Haber M, Norris MD, Cheung BB, Byrne JA, Ziegler DS, Marshall GM, Dinger ME, Codd R, Zhang XD, Liu T.

Oncotarget. 2016 Nov 29;7(48):79217-79232. doi: 10.18632/oncotarget.12640.


Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression.

Evageliou NF, Haber M, Vu A, Laetsch TW, Murray J, Gamble LD, Cheng NC, Liu K, Reese M, Corrigan KA, Ziegler DS, Webber H, Hayes CS, Pawel B, Marshall GM, Zhao H, Gilmour SK, Norris MD, Hogarty MD.

Clin Cancer Res. 2016 Sep 1;22(17):4391-404. doi: 10.1158/1078-0432.CCR-15-2539. Epub 2016 Mar 24.


Case Report of Spontaneous Resolution of a Congenital Glioblastoma.

Davis T, Doyle H, Tobias V, Ellison DW, Ziegler DS.

Pediatrics. 2016 Apr;137(4). pii: e20151241. doi: 10.1542/peds.2015-1241. Epub 2016 Mar 15.


Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.

Carter DR, Murray J, Cheung BB, Gamble L, Koach J, Tsang J, Sutton S, Kalla H, Syed S, Gifford AJ, Issaeva N, Biktasova A, Atmadibrata B, Sun Y, Sokolowski N, Ling D, Kim PY, Webber H, Clark A, Ruhle M, Liu B, Oberthuer A, Fischer M, Byrne J, Saletta F, Thwe le M, Purmal A, Haderski G, Burkhart C, Speleman F, De Preter K, Beckers A, Ziegler DS, Liu T, Gurova KV, Gudkov AV, Norris MD, Haber M, Marshall GM.

Sci Transl Med. 2015 Nov 4;7(312):312ra176. doi: 10.1126/scitranslmed.aab1803.


The wide-ranging clinical implications of the short telomere syndromes.

Barbaro PM, Ziegler DS, Reddel RR.

Intern Med J. 2016 Apr;46(4):393-403. doi: 10.1111/imj.12868. Review.


Never say never.

Ziegler DS.

J Clin Oncol. 2015 Feb 10;33(5):518-20. doi: 10.1200/JCO.2014.58.7717. Epub 2015 Jan 5. No abstract available.


Outcomes in multifocal neuroblastoma as part of the neurocristopathy syndrome.

Williams P, Wegner E, Ziegler DS.

Pediatrics. 2014 Aug;134(2):e611-6. doi: 10.1542/peds.2013-3340.


Molecular profiling of childhood cancer: Biomarkers and novel therapies.

Saletta F, Wadham C, Ziegler DS, Marshall GM, Haber M, McCowage G, Norris MD, Byrne JA.

BBA Clin. 2014 Jun 28;1:59-77. doi: 10.1016/j.bbacli.2014.06.003. eCollection 2014 Jun. Review.


Antibody therapy for pediatric leukemia.

Vedi A, Ziegler DS.

Front Oncol. 2014 Apr 21;4:82. doi: 10.3389/fonc.2014.00082. eCollection 2014. Review.


A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.

Shah S, Schrader KA, Waanders E, Timms AE, Vijai J, Miething C, Wechsler J, Yang J, Hayes J, Klein RJ, Zhang J, Wei L, Wu G, Rusch M, Nagahawatte P, Ma J, Chen SC, Song G, Cheng J, Meyers P, Bhojwani D, Jhanwar S, Maslak P, Fleisher M, Littman J, Offit L, Rau-Murthy R, Fleischut MH, Corines M, Murali R, Gao X, Manschreck C, Kitzing T, Murty VV, Raimondi S, Kuiper RP, Simons A, Schiffman JD, Onel K, Plon SE, Wheeler D, Ritter D, Ziegler DS, Tucker K, Sutton R, Chenevix-Trench G, Li J, Huntsman DG, Hansford S, Senz J, Walsh T, Lee M, Hahn CN, Roberts K, King MC, Lo SM, Levine RL, Viale A, Socci ND, Nathanson KL, Scott HS, Daly M, Lipkin SM, Lowe SW, Downing JR, Altshuler D, Sandlund JT, Horwitz MS, Mullighan CG, Offit K.

Nat Genet. 2013 Oct;45(10):1226-1231. doi: 10.1038/ng.2754. Epub 2013 Sep 8.


Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review.

Mateos MK, O'Brien TA, Oswald C, Gabriel M, Ziegler DS, Cohn RJ, Russell SJ, Barbaric D, Marshall GM, Trahair TN.

Pediatr Blood Cancer. 2013 Sep;60(9):1520-7. doi: 10.1002/pbc.24559. Epub 2013 Jun 3.


Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.

Gamble LD, Hogarty MD, Liu X, Ziegler DS, Marshall G, Norris MD, Haber M.

Front Oncol. 2012 Nov 16;2:162. doi: 10.3389/fonc.2012.00162. eCollection 2012.


Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma.

Keating J, Tsoli M, Hallahan AR, Ingram WJ, Haber M, Ziegler DS.

Mol Cancer Ther. 2012 Dec;11(12):2654-63. doi: 10.1158/1535-7163.MCT-12-0352. Epub 2012 Sep 25.


Neonatal Sweet syndrome: a potential marker of serious systemic illness.

Gray PE, Bock V, Ziegler DS, Wargon O.

Pediatrics. 2012 May;129(5):e1353-9. doi: 10.1542/peds.2011-1854. Epub 2012 Apr 16.


Australian Paediatric Surveillance Unit study of haemoglobinopathies in Australian children.

Argent E, Emder P, Monagle P, Mowat D, Petterson T, Russell S, Sachdev R, Stone C, Ziegler DS.

J Paediatr Child Health. 2012 Apr;48(4):356-60. doi: 10.1111/j.1440-1754.2011.02236.x. Epub 2011 Dec 13.


Treatment of children with poor risk solid tumors by further escalation of the VETOPEC regimen including very high-dose cyclophosphamide and peripheral stem cell support: an Australian and New Zealand Children's Hematology and Oncology Group study.

McCowage GB, Mrongovius R, Alvaro F, Cohn RJ, Ziegler DS, Oswald C, White L; Australian and New Zealand Children's Haematology and Oncology Group (ANZCHOG).

Pediatr Blood Cancer. 2011 Dec 1;57(6):958-64. doi: 10.1002/pbc.23042. Epub 2011 Jul 25.


A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo.

Ziegler DS, Keating J, Kesari S, Fast EM, Zawel L, Ramakrishna N, Barnes J, Kieran MW, Veldhuijzen van Zanten SE, Kung AL.

Neuro Oncol. 2011 Aug;13(8):820-9. doi: 10.1093/neuonc/nor066. Epub 2011 Jul 1.


Reduced incidence of second solid tumors in survivors of childhood Hodgkin's lymphoma treated without radiation therapy.

Barbaro PM, Johnston K, Dalla-Pozza L, Cohn RJ, Wang YA, Marshall GM, Ziegler DS.

Ann Oncol. 2011 Dec;22(12):2569-74. doi: 10.1093/annonc/mdr013. Epub 2011 Mar 10.


False-positive MIBG scans with normal computed tomography imaging in patients with high-risk neuroblastoma.

Satharasinghe K, Trahair TN, Barbaric D, O'Brien TA, Russell SJ, Cohn RJ, Marshall GM, Ziegler DS.

J Clin Oncol. 2009 Dec 1;27(34):e233-4; author reply e235. doi: 10.1200/JCO.2009.24.0036. Epub 2009 Nov 2. No abstract available.


Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins.

Ziegler DS, Wright RD, Kesari S, Lemieux ME, Tran MA, Jain M, Zawel L, Kung AL.

J Clin Invest. 2008 Sep;118(9):3109-22. doi: 10.1172/JCI34120.


Anti-apoptosis mechanisms in malignant gliomas.

Ziegler DS, Kung AL, Kieran MW.

J Clin Oncol. 2008 Jan 20;26(3):493-500. doi: 10.1200/JCO.2007.13.9717. Review. Erratum in: J Clin Oncol. 2008 Apr 1;26(10):1773.


Therapeutic targeting of apoptosis pathways in cancer.

Ziegler DS, Kung AL.

Curr Opin Oncol. 2008 Jan;20(1):97-103. Review.


Efficacy of vincristine and etoposide with escalating cyclophosphamide in poor-prognosis pediatric brain tumors.

Ziegler DS, Cohn RJ, McCowage G, Alvaro F, Oswald C, Mrongovius R, White L; Australian and New Zealand Children's Study Group.

Neuro Oncol. 2006 Jan;8(1):53-9.


Goats' milk quackery.

Ziegler DS, Russell SJ, Rozenberg G, James CA, Trahair TN, O'Brien TA.

J Paediatr Child Health. 2005 Nov;41(11):569-71. No abstract available.


Long-term survival following a phase I/II trial with VETOPEC for solid tumors in childhood.

Ziegler DS, McCowage G, Cohn RJ, White L.

J Pediatr Hematol Oncol. 2006 Jan;28(1):40-2.


Retinoic acid may increase the risk of bone marrow transplant nephropathy.

Haysom L, Ziegler DS, Cohn RJ, Rosenberg AR, Carroll SL, Kainer G.

Pediatr Nephrol. 2005 Apr;20(4):534-8. Epub 2005 Feb 18.


Advances in childhood leukaemia: successful clinical-trials research leads to individualised therapy.

Ziegler DS, Dalla Pozza L, Waters KD, Marshall GM.

Med J Aust. 2005 Jan 17;182(2):78-81. Review.


PCR for monoclonal gene rearrangements can differentiate infantile acute lymphoblastic leukemia from cytomegalovirus infection.

Ziegler DS, Cohn RJ, Sutton R, Norris M, Duffy BJ.

Leuk Res. 2005 Jan;29(1):111-2. No abstract available.


Throat clearing in asthma.

Ziegler DS.

N Engl J Med. 2003 Jul 10;349(2):194-5; author reply 194-5. No abstract available.


Upper airway obstruction induced by a caustic substance found responsive to nebulised adrenaline.

Ziegler DS, Bent GP.

J Paediatr Child Health. 2001 Oct;37(5):524-5. No abstract available.


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