Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 115


RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.

Papaspyropoulos A, Bradley L, Thapa A, Leung CY, Toskas K, Koennig D, Pefani DE, Raso C, Grou C, Hamilton G, Vlahov N, Grawenda A, Haider S, Chauhan J, Buti L, Kanapin A, Lu X, Buffa F, Dianov G, von Kriegsheim A, Matallanas D, Samsonova A, Zernicka-Goetz M, O'Neill E.

Nat Commun. 2018 Jan 30;9(1):424. doi: 10.1038/s41467-017-02786-5.


Erratum: Revisiting the Warnock rule.

Hurlbut JB, Hyun I, Levine AD, Lovell-Badge R, Lunshof JE, Matthews KRW, Mills P, Murdoch A, Pera MF, Scott CT, Tizzard J, Warnock M, Zernicka-Goetz M, Zhou Q, Zoloth L.

Nat Biotechnol. 2017 Dec 8;35(12):1211. doi: 10.1038/nbt1217-1211d.


Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.

Shahbazi MN, Scialdone A, Skorupska N, Weberling A, Recher G, Zhu M, Jedrusik A, Devito LG, Noli L, Macaulay IC, Buecker C, Khalaf Y, Ilic D, Voet T, Marioni JC, Zernicka-Goetz M.

Nature. 2017 Dec 14;552(7684):239-243. doi: 10.1038/nature24675. Epub 2017 Nov 29.


Revisiting the Warnock rule.

Hurlbut JB, Hyun I, Levine AD, Lovell-Badge R, Lunshof JE, Matthews KRW, Mills P, Murdoch A, Pera MF, Scott CT, Tizzard J, Warnock M, Zernicka-Goetz M, Zhou Q, Zoloth L.

Nat Biotechnol. 2017 Nov 9;35(11):1029-1042. doi: 10.1038/nbt.4015. No abstract available. Erratum in: Nat Biotechnol. 2017 Dec 8;35(12 ):1211.


Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis.

Strauss B, Harrison A, Coelho PA, Yata K, Zernicka-Goetz M, Pines J.

J Cell Biol. 2018 Jan 2;217(1):179-193. doi: 10.1083/jcb.201612147. Epub 2017 Oct 26.


Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo.

Zhu M, Leung CY, Shahbazi MN, Zernicka-Goetz M.

Nat Commun. 2017 Oct 13;8(1):921. doi: 10.1038/s41467-017-00977-8.


Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes.

Bury L, Coelho PA, Simeone A, Ferries S, Eyers CE, Eyers PA, Zernicka-Goetz M, Glover DM.

J Cell Biol. 2017 Nov 6;216(11):3571-3590. doi: 10.1083/jcb.201606077. Epub 2017 Sep 28.


Delayed APC/C activation extends the first mitosis of mouse embryos.

Ajduk A, Strauss B, Pines J, Zernicka-Goetz M.

Sci Rep. 2017 Aug 29;7(1):9682. doi: 10.1038/s41598-017-09526-1.


The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo.

Goolam M, Zernicka-Goetz M.

Development. 2017 Apr 15;144(8):1450-1461. doi: 10.1242/dev.144139. Epub 2017 Mar 13.


Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro.

Harrison SE, Sozen B, Christodoulou N, Kyprianou C, Zernicka-Goetz M.

Science. 2017 Apr 14;356(6334). pii: eaal1810. doi: 10.1126/science.aal1810. Epub 2017 Mar 2.


Andrzej K. Tarkowski 1933-2016.

Zernicka-Goetz M.

Nat Cell Biol. 2016 Nov 29;18(12):1261. doi: 10.1038/ncb3446. No abstract available.


Polarity in Cell-Fate Acquisition in the Early Mouse Embryo.

Leung CY, Zhu M, Zernicka-Goetz M.

Curr Top Dev Biol. 2016;120:203-34. doi: 10.1016/bs.ctdb.2016.04.008. Epub 2016 Jun 7. Review.


Self-organization of the human embryo in the absence of maternal tissues.

Shahbazi MN, Jedrusik A, Vuoristo S, Recher G, Hupalowska A, Bolton V, Fogarty NNM, Campbell A, Devito L, Ilic D, Khalaf Y, Niakan KK, Fishel S, Zernicka-Goetz M.

Nat Cell Biol. 2016 Jun;18(6):700-708. doi: 10.1038/ncb3347. Epub 2016 May 4.


Self-organization of the in vitro attached human embryo.

Deglincerti A, Croft GF, Pietila LN, Zernicka-Goetz M, Siggia ED, Brivanlou AH.

Nature. 2016 May 12;533(7602):251-4. doi: 10.1038/nature17948. Epub 2016 May 4.


Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential.

Bolton H, Graham SJ, Van der Aa N, Kumar P, Theunis K, Fernandez Gallardo E, Voet T, Zernicka-Goetz M.

Nat Commun. 2016 Mar 29;7:11165. doi: 10.1038/ncomms11165.


Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos.

Goolam M, Scialdone A, Graham SJL, Macaulay IC, Jedrusik A, Hupalowska A, Voet T, Marioni JC, Zernicka-Goetz M.

Cell. 2016 Mar 24;165(1):61-74. doi: 10.1016/j.cell.2016.01.047.


The Acquisition of Cell Fate in Mouse Development: How Do Cells First Become Heterogeneous?

Graham SJ, Zernicka-Goetz M.

Curr Top Dev Biol. 2016;117:671-95. doi: 10.1016/bs.ctdb.2015.11.021. Epub 2016 Jan 21. Review.


The BAF chromatin remodelling complex is an epigenetic regulator of lineage specification in the early mouse embryo.

Panamarova M, Cox A, Wicher KB, Butler R, Bulgakova N, Jeon S, Rosen B, Seong RH, Skarnes W, Crabtree G, Zernicka-Goetz M.

Development. 2016 Apr 15;143(8):1271-83. doi: 10.1242/dev.131961. Epub 2016 Mar 7.


Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse.

Coelho PA, Bury L, Shahbazi MN, Liakath-Ali K, Tate PH, Wormald S, Hindley CJ, Huch M, Archer J, Skarnes WC, Zernicka-Goetz M, Glover DM.

Open Biol. 2015 Dec;5(12):150209. doi: 10.1098/rsob.150209.


Polarity and cell division orientation in the cleavage embryo: from worm to human.

Ajduk A, Zernicka-Goetz M.

Mol Hum Reprod. 2016 Oct;22(10):691-703. Epub 2015 Dec 9.


Mapping the journey from totipotency to lineage specification in the mouse embryo.

Leung CY, Zernicka-Goetz M.

Curr Opin Genet Dev. 2015 Oct;34:71-6. doi: 10.1016/j.gde.2015.08.002. Epub 2015 Sep 3. Review.


Development of the anterior-posterior axis is a self-organizing process in the absence of maternal cues in the mouse embryo.

Bedzhov I, Bialecka M, Zielinska A, Kosalka J, Antonica F, Thompson AJ, Franze K, Zernicka-Goetz M.

Cell Res. 2015 Dec;25(12):1368-71. doi: 10.1038/cr.2015.104. Epub 2015 Sep 4. No abstract available.


G&T-seq: parallel sequencing of single-cell genomes and transcriptomes.

Macaulay IC, Haerty W, Kumar P, Li YI, Hu TX, Teng MJ, Goolam M, Saurat N, Coupland P, Shirley LM, Smith M, Van der Aa N, Banerjee R, Ellis PD, Quail MA, Swerdlow HP, Zernicka-Goetz M, Livesey FJ, Ponting CP, Voet T.

Nat Methods. 2015 Jun;12(6):519-22. doi: 10.1038/nmeth.3370. Epub 2015 Apr 27.


Cell death and morphogenesis during early mouse development: are they interconnected?

Bedzhov I, Zernicka-Goetz M.

Bioessays. 2015 Apr;37(4):372-8. doi: 10.1002/bies.201400147. Epub 2015 Jan 15.


Correction to: 'Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo'.

Bedzhov I, Graham SJ, Yan Leung C, Zernicka-Goetz M.

Philos Trans R Soc Lond B Biol Sci. 2015 Feb 5;370(1661):20140339. doi: 10.1098/rstb.2014.0339. No abstract available.


BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo.

Graham SJ, Wicher KB, Jedrusik A, Guo G, Herath W, Robson P, Zernicka-Goetz M.

Nat Commun. 2014 Dec 16;5:5667. doi: 10.1038/ncomms6667.


Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition.

Jedrusik A, Cox A, Wicher KB, Glover DM, Zernicka-Goetz M.

Dev Biol. 2015 Feb 15;398(2):147-52. doi: 10.1016/j.ydbio.2014.12.004. Epub 2014 Dec 13.


A tribute to Sir John Gurdon.

Rosenthal N, Zernicka-Goetz M.

Differentiation. 2014 Jul;88(1):1-2. doi: 10.1016/j.diff.2014.11.001. Epub 2014 Nov 20. No abstract available.


In vitro culture of mouse blastocysts beyond the implantation stages.

Bedzhov I, Leung CY, Bialecka M, Zernicka-Goetz M.

Nat Protoc. 2014 Dec;9(12):2732-9. doi: 10.1038/nprot.2014.186. Epub 2014 Oct 30.


Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo.

Bedzhov I, Graham SJ, Leung CY, Zernicka-Goetz M.

Philos Trans R Soc Lond B Biol Sci. 2014 Dec 5;369(1657). pii: 20130538. doi: 10.1098/rstb.2013.0538. Review. Erratum in: Philos Trans R Soc Lond B Biol Sci. 2015 Feb 5;370(1661):20140339.


From pluripotency to differentiation: laying foundations for the body pattern in the mouse embryo.

Zernicka-Goetz M, Hadjantonakis AK.

Philos Trans R Soc Lond B Biol Sci. 2014 Dec 5;369(1657). pii: 20130535. doi: 10.1098/rstb.2013.0535. No abstract available.


The basal position of nuclei is one pre-requisite for asymmetric cell divisions in the early mouse embryo.

Ajduk A, Biswas Shivhare S, Zernicka-Goetz M.

Dev Biol. 2014 Aug 15;392(2):133-40. doi: 10.1016/j.ydbio.2014.05.009. Epub 2014 May 20.


Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation.

Bedzhov I, Zernicka-Goetz M.

Cell. 2014 Feb 27;156(5):1032-44. doi: 10.1016/j.cell.2014.01.023. Epub 2014 Feb 13.


Citrullination regulates pluripotency and histone H1 binding to chromatin.

Christophorou MA, Castelo-Branco G, Halley-Stott RP, Oliveira CS, Loos R, Radzisheuskaya A, Mowen KA, Bertone P, Silva JC, Zernicka-Goetz M, Nielsen ML, Gurdon JB, Kouzarides T.

Nature. 2014 Mar 6;507(7490):104-8. doi: 10.1038/nature12942. Epub 2014 Jan 26.


Spindle formation in the mouse embryo requires Plk4 in the absence of centrioles.

Coelho PA, Bury L, Sharif B, Riparbelli MG, Fu J, Callaini G, Glover DM, Zernicka-Goetz M.

Dev Cell. 2013 Dec 9;27(5):586-97. doi: 10.1016/j.devcel.2013.09.029. Epub 2013 Nov 21.


The differential response to Fgf signalling in cells internalized at different times influences lineage segregation in preimplantation mouse embryos.

Morris SA, Graham SJ, Jedrusik A, Zernicka-Goetz M.

Open Biol. 2013 Nov 20;3(11):130104. doi: 10.1098/rsob.130104.


Introduction to the special issue "Molecular Players in Early Pregnancy".

Duan EK, Wang H, Zernicka-Goetz M.

Mol Aspects Med. 2013 Oct;34(5):vi-vii. doi: 10.1016/S0098-2997(13)00054-X. No abstract available.


Quality control of embryo development.

Ajduk A, Zernicka-Goetz M.

Mol Aspects Med. 2013 Oct;34(5):903-18. doi: 10.1016/j.mam.2013.03.001. Epub 2013 Apr 4. Review.


Asymmetric localization of Cdx2 mRNA during the first cell-fate decision in early mouse development.

Skamagki M, Wicher KB, Jedrusik A, Ganguly S, Zernicka-Goetz M.

Cell Rep. 2013 Feb 21;3(2):442-57. doi: 10.1016/j.celrep.2013.01.006. Epub 2013 Jan 31.


Development: do mouse embryos play dice?

Zernicka-Goetz M.

Curr Biol. 2013 Jan 7;23(1):R15-7. doi: 10.1016/j.cub.2012.10.032.


Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency.

Pasque V, Radzisheuskaya A, Gillich A, Halley-Stott RP, Panamarova M, Zernicka-Goetz M, Surani MA, Silva JC.

J Cell Sci. 2012 Dec 15;125(Pt 24):6094-104. doi: 10.1242/jcs.113019. Epub 2012 Oct 17.


Developmental plasticity is bound by pluripotency and the Fgf and Wnt signaling pathways.

Morris SA, Guo Y, Zernicka-Goetz M.

Cell Rep. 2012 Oct 25;2(4):756-65. doi: 10.1016/j.celrep.2012.08.029. Epub 2012 Oct 4.


Formation of distinct cell types in the mouse blastocyst.

Morris SA, Zernicka-Goetz M.

Results Probl Cell Differ. 2012;55:203-17. doi: 10.1007/978-3-642-30406-4_11. Review.


Advances in embryo selection methods.

Ajduk A, Zernicka-Goetz M.

F1000 Biol Rep. 2012;4:11. doi: 10.3410/B4-11. Epub 2012 Jun 1.


Protein arginine methyltransferase 6 regulates embryonic stem cell identity.

Lee YH, Ma H, Tan TZ, Ng SS, Soong R, Mori S, Fu XY, Zernicka-Goetz M, Wu Q.

Stem Cells Dev. 2012 Sep 20;21(14):2613-22. doi: 10.1089/scd.2011.0330. Epub 2012 May 8.


Dynamics of anterior-posterior axis formation in the developing mouse embryo.

Morris SA, Grewal S, Barrios F, Patankar SN, Strauss B, Buttery L, Alexander M, Shakesheff KM, Zernicka-Goetz M.

Nat Commun. 2012 Feb 14;3:673. doi: 10.1038/ncomms1671.


Phospholipase C-ΞΆ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection.

Swann K, Windsor S, Campbell K, Elgmati K, Nomikos M, Zernicka-Goetz M, Amso N, Lai FA, Thomas A, Graham C.

Fertil Steril. 2012 Mar;97(3):742-7. doi: 10.1016/j.fertnstert.2011.12.013. Epub 2012 Jan 2.


Rhythmic actomyosin-driven contractions induced by sperm entry predict mammalian embryo viability.

Ajduk A, Ilozue T, Windsor S, Yu Y, Seres KB, Bomphrey RJ, Tom BD, Swann K, Thomas A, Graham C, Zernicka-Goetz M.

Nat Commun. 2011 Aug 9;2:417. doi: 10.1038/ncomms1424.


Proclaiming fate in the early mouse embryo.

Zernicka-Goetz M.

Nat Cell Biol. 2011 Feb;13(2):112-4. doi: 10.1038/ncb0211-112.


Supplemental Content

Loading ...
Support Center