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Tudor staphylococcal nuclease is a structure-specific ribonuclease that degrades RNA at unstructured regions during microRNA decay.

Li CL, Yang WZ, Shi Z, Yuan HS.

RNA. 2018 Feb 13. pii: rna.064501.117. doi: 10.1261/rna.064501.117. [Epub ahead of print]


Preoperative Evaluation of the Grade and Stability of Osteochondritis Dissecans of the Knee by Magnetic Resonance Imaging.

Ren C, Lang N, Chen W, Yuan HS.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Dec 20;39(6):768-773. doi: 10.3881/j.issn.1000-503X.2017.06.006.


Imaging Appearances and Pathologic Characteristics of Spinal Epidural Meningioma.

Zhang LH, Yuan HS.

AJNR Am J Neuroradiol. 2018 Jan;39(1):199-204. doi: 10.3174/ajnr.A5414. Epub 2017 Oct 19.


Structural insights into RNA unwinding and degradation by RNase R.

Chu LY, Hsieh TJ, Golzarroshan B, Chen YP, Agrawal S, Yuan HS.

Nucleic Acids Res. 2017 Nov 16;45(20):12015-12024. doi: 10.1093/nar/gkx880.


Comparison of FSE T2 W PROPELLER and 3D-FIESTA of 3 T MR for the internal auditory canal.

Wu HB, Yuan HS, Ma F, Zhao Q.

Clin Imaging. 2017 Sep - Oct;45:30-33. doi: 10.1016/j.clinimag.2016.09.001. Epub 2016 Oct 4.


Percutaneous radiofrequency ablation for spinal osteoid osteoma and osteoblastoma.

Wang B, Han SB, Jiang L, Yuan HS, Liu C, Zhu B, Liu ZJ, Liu XG.

Eur Spine J. 2017 Jul;26(7):1884-1892. doi: 10.1007/s00586-017-5080-0. Epub 2017 Apr 8.


Significance of Diffusion Tensor Imaging of Vastus Medialis Oblique in Recurrent Patellar Dislocation.

Liu LS, Zheng ZZ, Yuan HS.

Chin Med J (Engl). 2017 Mar 20;130(6):642-646. doi: 10.4103/0366-6999.201607.


A Volumetric and Functional Connectivity MRI Study of Brain Arginine-Vasopressin Pathways in Autistic Children.

Shou XJ, Xu XJ, Zeng XZ, Liu Y, Yuan HS, Xing Y, Jia MX, Wei QY, Han SP, Zhang R, Han JS.

Neurosci Bull. 2017 Apr;33(2):130-142. doi: 10.1007/s12264-017-0109-2. Epub 2017 Mar 3.


Structural Insights into a Unique Dimeric DEAD-Box Helicase CshA that Promotes RNA Decay.

Huen J, Lin CL, Golzarroshan B, Yi WL, Yang WZ, Yuan HS.

Structure. 2017 Mar 7;25(3):469-481. doi: 10.1016/j.str.2017.01.012. Epub 2017 Feb 23.


Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.

Lin JL, Wu CC, Yang WZ, Yuan HS.

Nucleic Acids Res. 2016 Dec 1;44(21):10480-10490. Epub 2016 Oct 13.


Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES).

Huang KW, Hsu KC, Chu LY, Yang JM, Yuan HS, Hsiao YY.

J Med Chem. 2016 Sep 8;59(17):8019-29. doi: 10.1021/acs.jmedchem.6b00794. Epub 2016 Aug 29.


Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G.

Lin JLJ, Nakagawa A, Skeen-Gaar R, Yang WZ, Zhao P, Zhang Z, Ge X, Mitani S, Xue D, Yuan HS.

Cell Rep. 2016 Jul 12;16(2):279-287. doi: 10.1016/j.celrep.2016.05.090. Epub 2016 Jun 23.


Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization.

Zhou Q, Li H, Li H, Nakagawa A, Lin JL, Lee ES, Harry BL, Skeen-Gaar RR, Suehiro Y, William D, Mitani S, Yuan HS, Kang BH, Xue D.

Science. 2016 Jul 22;353(6297):394-9. doi: 10.1126/science.aaf4777. Epub 2016 Jun 23.


Using an Old Drug to Target a New Drug Site: Application of Disulfiram to Target the Zn-Site in HCV NS5A Protein.

Lee YM, Duh Y, Wang ST, Lai MM, Yuan HS, Lim C.

J Am Chem Soc. 2016 Mar 23;138(11):3856-62. doi: 10.1021/jacs.6b00299. Epub 2016 Mar 14.


Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation.

Chiang CH, Grauffel C, Wu LS, Kuo PH, Doudeva LG, Lim C, Shen CK, Yuan HS.

Sci Rep. 2016 Feb 17;6:21581. doi: 10.1038/srep21581.


Aromatic residues in RNase T stack with nucleobases to guide the sequence-specific recognition and cleavage of nucleic acids.

Duh Y, Hsiao YY, Li CL, Huang JC, Yuan HS.

Protein Sci. 2015 Dec;24(12):1934-41. doi: 10.1002/pro.2800. Epub 2015 Sep 18.


Computed Tomography and Magnetic Resonance Manifestations of Spinal Pigmented Villonodular Synovitis.

Lang N, Yuan HS.

J Comput Assist Tomogr. 2015 Jul-Aug;39(4):601-6. doi: 10.1097/RCT.0000000000000244.


[Value of multiple b-value diffusion-weighted imaging for differentiation of benign and malignant pulmonary masses].

Wang XH, Duan JH, Yuan HS.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2014 Oct;36(5):510-5. doi: 10.3881/j.issn.1000-503X.2014.05.010. Chinese.


Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients.

Fang YS, Tsai KJ, Chang YJ, Kao P, Woods R, Kuo PH, Wu CC, Liao JY, Chou SC, Lin V, Jin LW, Yuan HS, Cheng IH, Tu PH, Chen YR.

Nat Commun. 2014 Sep 12;5:4824. doi: 10.1038/ncomms5824.


Structure and function of TatD exonuclease in DNA repair.

Chen YC, Li CL, Hsiao YY, Duh Y, Yuan HS.

Nucleic Acids Res. 2014;42(16):10776-85. doi: 10.1093/nar/gku732. Epub 2014 Aug 11.


Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.

Hsiao YY, Fang WH, Lee CC, Chen YP, Yuan HS.

PLoS Biol. 2014 Mar 4;12(3):e1001803. doi: 10.1371/journal.pbio.1001803. eCollection 2014 Mar.


The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.

Kuo PH, Chiang CH, Wang YT, Doudeva LG, Yuan HS.

Nucleic Acids Res. 2014 Apr;42(7):4712-22. doi: 10.1093/nar/gkt1407. Epub 2014 Jan 23.


[The effects of gastric bypass procedures on blood glucose, gastric inhibitory polypeptide and glucagon-like peptide-1 of normal glucose tolerance dogs].

Pan LZ, Bai RX, Song MM, Li YG, Zhou L, Zhong ZQ, Xu J, Yuan HS, Cui Z.

Zhonghua Wai Ke Za Zhi. 2013 Sep;51(9):831-3. Chinese.


Diagnosis and treatment of vertebral hemangiomas with neurologic deficit: a report of 29 cases and literature review.

Jiang L, Liu XG, Yuan HS, Yang SM, Li J, Wei F, Liu C, Dang L, Liu ZJ.

Spine J. 2014 Jun 1;14(6):944-54. doi: 10.1016/j.spinee.2013.07.450. Epub 2013 Oct 8. Review.


[Effect of tube voltage on digital chest radiograph for phantom and occupational exposed workers].

Wang XH, Liu DS, Xuan X, Kang H, Duan JH, Yuan HS.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2013 Sep;31(9):671-4. Chinese.


Identification of labile Zn sites in drug-target proteins.

Lee YM, Wang YT, Duh Y, Yuan HS, Lim C.

J Am Chem Soc. 2013 Sep 25;135(38):14028-31. doi: 10.1021/ja406300c. Epub 2013 Sep 11.


[Application of side to side anastomosis between the lesser curvature of stomach and jejunum in laparoscopic Roux-en-Y gastric bypass].

Bai RX, Li YG, Xu J, Zhong ZQ, Yan WM, Yuan HS, Song MM.

Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jul;16(7):648-50. Chinese.


[Effect of digital radiography processing parameters on digital chest radiograph for occupational exposed workers].

Wang XH, Liu DS, Xuan X, Kang H, Yuan HS.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2013 May;31(5):351-5. Chinese.


Tri-planar computed tomographic projection of three segments of the middle turbinate in a Chinese population.

Wu HB, Yuan HS, Zhu L.

Eur Arch Otorhinolaryngol. 2014 Mar;271(3):511-8. doi: 10.1007/s00405-013-2573-2. Epub 2013 Jun 11.


The truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates.

Wang YT, Kuo PH, Chiang CH, Liang JR, Chen YR, Wang S, Shen JC, Yuan HS.

J Biol Chem. 2013 Mar 29;288(13):9049-57. doi: 10.1074/jbc.M112.438564. Epub 2013 Jan 31.


Knockdown of Ezrin by RNA interference reverses malignant behavior of human pancreatic cancer cells in vitro.

Zhong ZQ, Song MM, He Y, Cheng S, Yuan HS.

Asian Pac J Cancer Prev. 2012;13(8):3781-9.


Epidemiological survey of ossification of the ligamentum flavum in thoracic spine: CT imaging observation of 993 cases.

Lang N, Yuan HS, Wang HL, Liao J, Li M, Guo FX, Shi S, Chen ZQ.

Eur Spine J. 2013 Apr;22(4):857-62. doi: 10.1007/s00586-012-2492-8. Epub 2012 Sep 15.


Aggressive vertebral hemangioma of the thoracic spine without typical radiological appearance.

Dang L, Liu C, Yang SM, Jiang L, Liu ZJ, Liu XG, Yuan HS, Wei F, Yu M.

Eur Spine J. 2012 Oct;21(10):1994-9. doi: 10.1007/s00586-012-2349-1. Epub 2012 Jun 26.


How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes.

Hsiao YY, Duh Y, Chen YP, Wang YT, Yuan HS.

Nucleic Acids Res. 2012 Sep;40(16):8144-54. doi: 10.1093/nar/gks548. Epub 2012 Jun 19.


Clinical analysis of concomitant valve replacement and bipolar radiofrequency ablation in 191 patients.

Dong L, Fu B, Teng X, Yuan HS, Zhao SL, Ren L.

J Thorac Cardiovasc Surg. 2013 Apr;145(4):1013-7. doi: 10.1016/j.jtcvs.2012.05.009. Epub 2012 Jun 5.


Knockdown of radixin by RNA interference suppresses the growth of human pancreatic cancer cells in vitro and in vivo.

Chen SD, Song MM, Zhong ZQ, Li N, Wang PL, Cheng S, Bai RX, Yuan HS.

Asian Pac J Cancer Prev. 2012;13(3):753-9.


Malignant peripheral nerve sheath tumor in spine: imaging manifestations.

Lang N, Liu XG, Yuan HS.

Clin Imaging. 2012 May-Jun;36(3):209-15. doi: 10.1016/j.clinimag.2011.08.015.


Permanent implantation of iodine-125 seeds as a salvage therapy for recurrent head and neck carcinoma after radiotherapy.

Meng N, Jiang YL, Wang JJ, Ran WQ, Yuan HS, Qu A, Jiang P, Yang RJ.

Cancer Invest. 2012 Mar;30(3):236-42. doi: 10.3109/07357907.2012.654869.


[Hyperdense middle cerebral artery sign among patients with severe ischemic attack on ultra-early phase].

Song HS, Yuan HS, Fan DS.

Beijing Da Xue Xue Bao Yi Xue Ban. 2012 Feb 18;44(1):142-6. Chinese.


CT-guided percutaneous radiofrequency ablation of spinal osteoid osteoma.

Liu C, Liu XG, Zhu B, Yuan HS, Han SB, Ma YQ.

Chin Med J (Engl). 2011 Dec;124(23):4083-5.


Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans.

Lin JL, Nakagawa A, Lin CL, Hsiao YY, Yang WZ, Wang YT, Doudeva LG, Skeen-Gaar RR, Xue D, Yuan HS.

J Biol Chem. 2012 Mar 2;287(10):7110-20. doi: 10.1074/jbc.M111.316075. Epub 2012 Jan 5.


Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation.

Lin CL, Wang YT, Yang WZ, Hsiao YY, Yuan HS.

Nucleic Acids Res. 2012 May;40(9):4146-57. doi: 10.1093/nar/gkr1281. Epub 2011 Dec 30.


[Self-made pygal cloth sling for the treatment of congenital dislocation of hip in infants].

Wang GQ, Yang RJ, Kang XX, Wen YH, Yuan HS.

Zhongguo Gu Shang. 2011 Sep;24(9):765-7. Chinese.


Recombination in the nonstructural gene region in type 2 dengue viruses.

Su MW, Yuan HS, Chu WC.

Intervirology. 2012;55(3):225-30. doi: 10.1159/000327786. Epub 2011 Aug 3.


Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation.

Hsiao YY, Yang CC, Lin CL, Lin JL, Duh Y, Yuan HS.

Nat Chem Biol. 2011 Apr;7(4):236-43. doi: 10.1038/nchembio.524. Epub 2011 Feb 13.


[Multi-modality magnetic resonance imaging features of cognitive function in mild cognitive impairment].

Wang HL, Yuan HS, Su LM, Zhu Y, Liao J, Zhang MY, Li T, Yu X.

Zhonghua Nei Ke Za Zhi. 2010 Aug;49(8):680-3. Chinese.


Surgical measurement to sphenoid sinus for the Chinese in Asia based on CT using sagittal reconstruction images.

Wu HB, Zhu L, Yuan HS, Hou C.

Eur Arch Otorhinolaryngol. 2011 Feb;268(2):241-6. doi: 10.1007/s00405-010-1373-1. Epub 2010 Sep 21.


CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers.

Jiang YL, Meng N, Wang JJ, Jiang P, Yuan HSh, Liu C, Qu A, Yang RJ.

Radiat Oncol. 2010 Jul 30;5:68. doi: 10.1186/1748-717X-5-68.


Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation.

Yang CC, Wang YT, Hsiao YY, Doudeva LG, Kuo PH, Chow SY, Yuan HS.

RNA. 2010 Sep;16(9):1748-59. doi: 10.1261/rna.2180810. Epub 2010 Jul 21.

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