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Chest wall dose reduction using noncoplanar volumetric modulated arc radiation therapy for lung stereotactic ablative radiation therapy.

Yu AS, Maxim PG, Loo BW Jr., Gensheimer MF.

Pract Radiat Oncol. 2017 Dec 19. pii: S1879-8500(17)30377-6. doi: 10.1016/j.prro.2017.12.005. [Epub ahead of print]


The Value of Genetic Testing in Polycystic Kidney Diseases Illustrated by a Family With PKD2 and COL4A1 Mutations.

Cornec-Le Gall E, Chebib FT, Madsen CD, Senum SR, Heyer CM, Lanpher BC, Patterson MC, Albright RC, Yu AS, Torres VE; HALT Progression of Polycystic Kidney Disease Group Investigators, Harris PC.

Am J Kidney Dis. 2018 Jan 27. pii: S0272-6386(17)31135-6. doi: 10.1053/j.ajkd.2017.11.015. [Epub ahead of print]


Intrafractional Tracking Accuracy of a Transperineal Ultrasound Image Guidance System for Prostate Radiotherapy.

Yu AS, Najafi M, Hristov DH, Phillips T.

Technol Cancer Res Treat. 2017 Dec;16(6):1067-1078. doi: 10.1177/1533034617728643. Epub 2017 Sep 21.


Baseline total kidney volume and the rate of kidney growth are associated with chronic kidney disease progression in Autosomal Dominant Polycystic Kidney Disease.

Yu ASL, Shen C, Landsittel DP, Harris PC, Torres VE, Mrug M, Bae KT, Grantham JJ, Rahbari-Oskoui FF, Flessner MF, Bennett WM, Chapman AB; Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP).

Kidney Int. 2018 Mar;93(3):691-699. doi: 10.1016/j.kint.2017.09.027. Epub 2017 Dec 28.


Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease.

Nowak KL, You Z, Gitomer B, Brosnahan G, Torres VE, Chapman AB, Perrone RD, Steinman TI, Abebe KZ, Rahbari-Oskoui FF, Yu ASL, Harris PC, Bae KT, Hogan M, Miskulin D, Chonchol M.

J Am Soc Nephrol. 2018 Feb;29(2):571-578. doi: 10.1681/ASN.2017070819. Epub 2017 Nov 8.


Sexual Dimorphic Pattern of Renal Transporters and Electrolyte Homeostasis.

Veiras LC, Girardi ACC, Curry J, Pei L, Ralph DL, Tran A, Castelo-Branco RC, Pastor-Soler N, Arranz CT, Yu ASL, McDonough AA.

J Am Soc Nephrol. 2017 Dec;28(12):3504-3517. doi: 10.1681/ASN.2017030295. Epub 2017 Aug 3.


Paracellular transport and energy utilization in the renal tubule.


Curr Opin Nephrol Hypertens. 2017 Sep;26(5):398-404. doi: 10.1097/MNH.0000000000000348.


Paracellular transport as a strategy for energy conservation by multicellular organisms?


Tissue Barriers. 2017 Apr 3;5(2):e1301852. doi: 10.1080/21688370.2017.1301852. Epub 2017 Mar 3.


Performance of the CKD-EPI Equation to Estimate GFR in a Longitudinal Study of Autosomal Dominant Polycystic Kidney Disease.

Shen C, Landsittel D, Irazabal MV, Yu AS, Chapman AB, Mrug M, Grantham JJ, Bae KT, Bennett WM, Flessner MF, Torres VE; CRISP Investigators.

Am J Kidney Dis. 2017 Mar;69(3):482-484. doi: 10.1053/j.ajkd.2016.10.021. Epub 2016 Dec 24. No abstract available.


Dietary salt restriction is beneficial to the management of autosomal dominant polycystic kidney disease.

Torres VE, Abebe KZ, Schrier RW, Perrone RD, Chapman AB, Yu AS, Braun WE, Steinman TI, Brosnahan G, Hogan MC, Rahbari FF, Grantham JJ, Bae KT, Moore CG, Flessner MF.

Kidney Int. 2017 Feb;91(2):493-500. doi: 10.1016/j.kint.2016.10.018. Epub 2016 Dec 16.


Vancomycin and the Risk of AKI: A Systematic Review and Meta-Analysis.

Sinha Ray A, Haikal A, Hammoud KA, Yu AS.

Clin J Am Soc Nephrol. 2016 Dec 7;11(12):2132-2140. Epub 2016 Nov 28. Review.


Automated segmentation of liver and liver cysts from bounded abdominal MR images in patients with autosomal dominant polycystic kidney disease.

Kim Y, Bae SK, Cheng T, Tao C, Ge Y, Chapman AB, Torres VE, Yu AS, Mrug M, Bennett WM, Flessner MF, Landsittel DP, Bae KT.

Phys Med Biol. 2016 Nov 21;61(22):7864-7880. Epub 2016 Oct 25.


Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule.

Ghezzi C, Yu AS, Hirayama BA, Kepe V, Liu J, Scafoglio C, Powell DR, Huang SC, Satyamurthy N, Barrio JR, Wright EM.

J Am Soc Nephrol. 2017 Mar;28(3):802-810. doi: 10.1681/ASN.2016050510. Epub 2016 Sep 12.


Current Challenges in the Evaluation and Management of Hyponatremia.

McGreal K, Budhiraja P, Jain N, Yu AS.

Kidney Dis (Basel). 2016 Jun;2(2):56-63. doi: 10.1159/000446267. Epub 2016 May 14. Review.


An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery.

Zeng H, Guo M, Zhou T, Tan L, Chong CN, Zhang T, Dong X, Xiang JZ, Yu AS, Yue L, Qi Q, Evans T, Graumann J, Chen S.

Cell Stem Cell. 2016 Sep 1;19(3):326-40. doi: 10.1016/j.stem.2016.07.002. Epub 2016 Aug 11.


Clinical Trials in Autosomal Dominant Polycystic Kidney Disease.

Yu ASL, El-Ters M, Winklhofer FT.

In: Li X, editor. Polycystic Kidney Disease [Internet]. Brisbane (AU): Codon Publications; 2015 Nov. Chapter 6.


Prognostic enrichment design in clinical trials for autosomal dominant polycystic kidney disease: the HALT-PKD clinical trial.

Irazabal MV, Abebe KZ, Bae KT, Perrone RD, Chapman AB, Schrier RW, Yu AS, Braun WE, Steinman TI, Harris PC, Flessner MF, Torres VE; HALT Investigators.

Nephrol Dial Transplant. 2017 Nov 1;32(11):1857-1865. doi: 10.1093/ndt/gfw294.


Claudin-2-mediated cation and water transport share a common pore.

Rosenthal R, Günzel D, Krug SM, Schulzke JD, Fromm M, Yu AS.

Acta Physiol (Oxf). 2017 Feb;219(2):521-536. doi: 10.1111/apha.12742. Epub 2016 Jul 20.


Paracellular epithelial sodium transport maximizes energy efficiency in the kidney.

Pei L, Solis G, Nguyen MT, Kamat N, Magenheimer L, Zhuo M, Li J, Curry J, McDonough AA, Fields TA, Welch WJ, Yu AS.

J Clin Invest. 2016 Jul 1;126(7):2509-18. doi: 10.1172/JCI83942. Epub 2016 May 23.


A cAMP and CREB-mediated feed-forward mechanism regulates GSK3β in polycystic kidney disease.

Kakade VR, Tao S, Rajagopal M, Zhou X, Li X, Yu AS, Calvet JP, Pandey P, Rao R.

J Mol Cell Biol. 2016 Dec;8(6):464-476. Epub 2016 May 4.


Engineered BDNF producing cells as a potential treatment for neurologic disease.

Deng P, Anderson JD, Yu AS, Annett G, Fink KD, Nolta JA.

Expert Opin Biol Ther. 2016 Aug;16(8):1025-33. doi: 10.1080/14712598.2016.1183641. Epub 2016 May 21. Review.


Investigation and control of a Plasmodium falciparum malaria outbreak in Shan Special Region II of Myanmar along the China-Myanmar Border from June to December 2014.

Liu H, Xu JW, Yang HL, Li M, Sun CD, Yin YJ, Zheng ZL, Zhang GY, Yu AS, Yang YH, Li CH, Ai S.

Infect Dis Poverty. 2016 Apr 25;5:32. doi: 10.1186/s40249-016-0127-8.


Cognitive Function and White Matter Changes Associated with Renal Transplantation.

Gupta A, Lepping RJ, Yu AS, Perea RD, Honea RA, Johnson DK, Brooks WM, Burns JM.

Am J Nephrol. 2016;43(1):50-7. doi: 10.1159/000444334. Epub 2016 Feb 20.


Predicted Mutation Strength of Nontruncating PKD1 Mutations Aids Genotype-Phenotype Correlations in Autosomal Dominant Polycystic Kidney Disease.

Heyer CM, Sundsbak JL, Abebe KZ, Chapman AB, Torres VE, Grantham JJ, Bae KT, Schrier RW, Perrone RD, Braun WE, Steinman TI, Mrug M, Yu AS, Brosnahan G, Hopp K, Irazabal MV, Bennett WM, Flessner MF, Moore CG, Landsittel D, Harris PC; HALT PKD and CRISP Investigators.

J Am Soc Nephrol. 2016 Sep;27(9):2872-84. doi: 10.1681/ASN.2015050583. Epub 2016 Jan 28.


Automated Segmentation of Kidneys from MR Images in Patients with Autosomal Dominant Polycystic Kidney Disease.

Kim Y, Ge Y, Tao C, Zhu J, Chapman AB, Torres VE, Yu AS, Mrug M, Bennett WM, Flessner MF, Landsittel DP, Bae KT; Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP).

Clin J Am Soc Nephrol. 2016 Apr 7;11(4):576-84. doi: 10.2215/CJN.08300815. Epub 2016 Jan 21.


Water and ion permeability of a claudin model: A computational study.

Laghaei R, Yu AS, Coalson RD.

Proteins. 2016 Mar;84(3):305-15. doi: 10.1002/prot.24969. Epub 2016 Feb 1.


Identification of key amino acid residues responsible for internal and external pH sensitivity of Orai1/STIM1 channels.

Tsujikawa H, Yu AS, Xie J, Yue Z, Yang W, He Y, Yue L.

Sci Rep. 2015 Nov 18;5:16747. doi: 10.1038/srep16747.


Claudin-2-dependent paracellular channels are dynamically gated.

Weber CR, Liang GH, Wang Y, Das S, Shen L, Yu AS, Nelson DJ, Turner JR.

Elife. 2015 Nov 14;4:e09906. doi: 10.7554/eLife.09906.


Effects of the GSK-3β inhibitor (2Z,3E)-6-bromoindirubin-3'-oxime upon ovarian cancer cells.

Yu AS, Zhao L.

Tumour Biol. 2016 Apr;37(4):4857-64. doi: 10.1007/s13277-015-4344-8. Epub 2015 Nov 2.


How specific is CRISPR/Cas9 really?

O'Geen H, Yu AS, Segal DJ.

Curr Opin Chem Biol. 2015 Dec;29:72-8. doi: 10.1016/j.cbpa.2015.10.001. Epub 2015 Oct 24. Review.


A phase 2 study of idelalisib plus rituximab in treatment-naïve older patients with chronic lymphocytic leukemia.

O'Brien SM, Lamanna N, Kipps TJ, Flinn I, Zelenetz AD, Burger JA, Keating M, Mitra S, Holes L, Yu AS, Johnson DM, Miller LL, Kim Y, Dansey RD, Dubowy RL, Coutre SE.

Blood. 2015 Dec 17;126(25):2686-94. doi: 10.1182/blood-2015-03-630947. Epub 2015 Oct 15.


Anatomic optimization of lung tumor stereotactic ablative radiation therapy.

Yu AS, von Eyben R, Yamamoto T, Diehn M, Shultz DB, Loo BW Jr, Maxim PG.

Pract Radiat Oncol. 2015 Nov-Dec;5(6):e607-13. doi: 10.1016/j.prro.2015.05.008. Epub 2015 Jul 28.


Serum Trimethylamine-N-Oxide is Elevated in CKD and Correlates with Coronary Atherosclerosis Burden.

Stubbs JR, House JA, Ocque AJ, Zhang S, Johnson C, Kimber C, Schmidt K, Gupta A, Wetmore JB, Nolin TD, Spertus JA, Yu AS.

J Am Soc Nephrol. 2016 Jan;27(1):305-13. doi: 10.1681/ASN.2014111063. Epub 2015 Jul 30.


Surface modification of La(0.8)Sr(0.2)CrO(3-δ)-YSZ dual-phase membranes for syngas production.

Yu AS, Oh TS, Zhu R, Gallegos A, Gorte RJ, Vohs JM.

Faraday Discuss. 2015;182:213-25. doi: 10.1039/c5fd00007f.


Durability of Hepatitis B e Antigen Seroconversion in Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir.

Fong TL, Tien A, Jo KJ, Chu D, Cheung E, Mena EA, Phan QQ, Yu AS, Mohammed W, Velasco A, LeDuc VH, Nguyen N, Han SB, Chang M, Bae HS, Cho YW, Tong MJ, Cooper SL.

Dig Dis Sci. 2015 Nov;60(11):3465-72. doi: 10.1007/s10620-015-3775-9. Epub 2015 Jul 3.


A novel closed-body model of spinal cord injury caused by high-pressure air blasts produces extensive axonal injury and motor impairments.

del Mar N, von Buttlar X, Yu AS, Guley NH, Reiner A, Honig MG.

Exp Neurol. 2015 Sep;271:53-71. doi: 10.1016/j.expneurol.2015.04.023. Epub 2015 May 7.


The Future of Polycystic Kidney Disease Research--As Seen By the 12 Kaplan Awardees.

Antignac C, Calvet JP, Germino GG, Grantham JJ, Guay-Woodford LM, Harris PC, Hildebrandt F, Peters DJ, Somlo S, Torres VE, Walz G, Zhou J, Yu AS.

J Am Soc Nephrol. 2015 Sep;26(9):2081-95. doi: 10.1681/ASN.2014121192. Epub 2015 May 7.


Noninvasive pulmonary nodule elastometry by CT and deformable image registration.

Negahdar M, Fasola CE, Yu AS, von Eyben R, Yamamoto T, Diehn M, Fleischmann D, Tian L, Loo BW, Maxim PG.

Radiother Oncol. 2015 Apr;115(1):35-40. doi: 10.1016/j.radonc.2015.03.015. Epub 2015 Mar 27.


Glycogen synthase kinase 3α regulates urine concentrating mechanism in mice.

Nørregaard R, Tao S, Nilsson L, Woodgett JR, Kakade V, Yu AS, Howard C, Rao R.

Am J Physiol Renal Physiol. 2015 Mar 15;308(6):F650-60. doi: 10.1152/ajprenal.00516.2014. Epub 2015 Jan 21.


Role of TRP channels in the cardiovascular system.

Yue Z, Xie J, Yu AS, Stock J, Du J, Yue L.

Am J Physiol Heart Circ Physiol. 2015 Feb 1;308(3):H157-82. doi: 10.1152/ajpheart.00457.2014. Epub 2014 Nov 21. Review.


The functional significance of common polymorphisms in zinc finger transcription factors.

Lockwood SH, Guan A, Yu AS, Zhang C, Zykovich A, Korf I, Rannala B, Segal DJ.

G3 (Bethesda). 2014 Jun 26;4(9):1647-55. doi: 10.1534/g3.114.012195.


Claudins and the kidney.

Yu AS.

J Am Soc Nephrol. 2015 Jan;26(1):11-9. doi: 10.1681/ASN.2014030284. Epub 2014 Jun 19. Review.


Polycystic kidney disease and cancer after renal transplantation.

Wetmore JB, Calvet JP, Yu AS, Lynch CF, Wang CJ, Kasiske BL, Engels EA.

J Am Soc Nephrol. 2014 Oct;25(10):2335-41. doi: 10.1681/ASN.2013101122. Epub 2014 May 22.


Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110δ, for relapsed/refractory chronic lymphocytic leukemia.

Brown JR, Byrd JC, Coutre SE, Benson DM, Flinn IW, Wagner-Johnston ND, Spurgeon SE, Kahl BS, Bello C, Webb HK, Johnson DM, Peterman S, Li D, Jahn TM, Lannutti BJ, Ulrich RG, Yu AS, Miller LL, Furman RR.

Blood. 2014 May 29;123(22):3390-7. doi: 10.1182/blood-2013-11-535047. Epub 2014 Mar 10.


Idelalisib, a selective inhibitor of phosphatidylinositol 3-kinase-δ, as therapy for previously treated indolent non-Hodgkin lymphoma.

Flinn IW, Kahl BS, Leonard JP, Furman RR, Brown JR, Byrd JC, Wagner-Johnston ND, Coutre SE, Benson DM, Peterman S, Cho Y, Webb HK, Johnson DM, Yu AS, Ulrich RG, Godfrey WR, Miller LL, Spurgeon SE.

Blood. 2014 May 29;123(22):3406-13. doi: 10.1182/blood-2013-11-538546. Epub 2014 Mar 10.


Comprehensive cysteine-scanning mutagenesis reveals Claudin-2 pore-lining residues with different intrapore locations.

Li J, Zhuo M, Pei L, Rajagopal M, Yu AS.

J Biol Chem. 2014 Mar 7;289(10):6475-84. doi: 10.1074/jbc.M113.536888. Epub 2014 Jan 16.


All systems normal: renal solute transport research in 2013.

Yu AS.

Curr Opin Nephrol Hypertens. 2013 Sep;22(5):531-2. doi: 10.1097/MNH.0b013e3283640080. No abstract available.


Neuropsychological correlates of performance based functional status in elder adult protective services referrals for capacity assessments.

Schillerstrom JE, Birkenfeld EM, Yu AS, Le MP, Goldstein DJ, Royall DR.

J Elder Abuse Negl. 2013;25(4):294-304. doi: 10.1080/08946566.2012.751831.


Conserved aromatic residue confers cation selectivity in claudin-2 and claudin-10b.

Li J, Zhuo M, Pei L, Yu AS.

J Biol Chem. 2013 Aug 2;288(31):22790-7. doi: 10.1074/jbc.M113.484238. Epub 2013 Jun 12.


Claudin-2 pore function requires an intramolecular disulfide bond between two conserved extracellular cysteines.

Li J, Angelow S, Linge A, Zhuo M, Yu AS.

Am J Physiol Cell Physiol. 2013 Jul 15;305(2):C190-6. doi: 10.1152/ajpcell.00074.2013. Epub 2013 May 15.

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