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Items: 1 to 50 of 91

1.

Exposure to Phthalate, an Endocrine Disrupting Chemical, Alters the First Trimester Placental Methylome and Transcriptome in Women.

Grindler NM, Vanderlinden L, Karthikraj R, Kannan K, Teal S, Polotsky AJ, Powell TL, Yang IV, Jansson T.

Sci Rep. 2018 Apr 17;8(1):6086. doi: 10.1038/s41598-018-24505-w.

2.

Meta-Analysis of Airway Epithelia Gene Expression in Asthma.

Tsai YH, Parker JS, Yang IV, Kelada SNP.

Eur Respir J. 2018 Apr 12. pii: 1701962. doi: 10.1183/13993003.01962-2017. [Epub ahead of print]

PMID:
29650561
3.

The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis.

Okamoto T, Mathai SK, Hennessy CE, Hancock LA, Walts AD, Stefanski AL, Brown KK, Lynch DA, Cosgrove GP, Groshong SD, Cool CD, Schwarz MI, Banda NK, Thurman JM, Yang IV, Holers VM, Schwartz DA.

Am J Physiol Lung Cell Mol Physiol. 2018 Mar 22. doi: 10.1152/ajplung.00395.2017. [Epub ahead of print]

PMID:
29565179
4.

Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury.

Koeppen M, Lee JW, Seo SW, Brodsky KS, Kreth S, Yang IV, Buttrick PM, Eckle T, Eltzschig HK.

Nat Commun. 2018 Feb 26;9(1):816. doi: 10.1038/s41467-018-03105-2.

5.

Epigenetic marks of in utero exposure to gestational diabetes and childhood adiposity outcomes: the EPOCH study.

Yang IV, Zhang W, Davidson EJ, Fingerlin TE, Kechris K, Dabelea D.

Diabet Med. 2018 May;35(5):612-620. doi: 10.1111/dme.13604. Epub 2018 Mar 13.

PMID:
29461653
6.

Role of epigenetics in the development of childhood asthma.

Davidson EJ, Yang IV.

Curr Opin Allergy Clin Immunol. 2018 Apr;18(2):132-138. doi: 10.1097/ACI.0000000000000429.

PMID:
29389731
7.

Methylene-tetrahydrofolate reductase contributes to allergic airway disease.

Eyring KR, Pedersen BS, Maclean KN, Stabler SP, Yang IV, Schwartz DA.

PLoS One. 2018 Jan 12;13(1):e0190916. doi: 10.1371/journal.pone.0190916. eCollection 2018.

8.

Low Neonatal Plasma n-6/n-3 PUFA Ratios Regulate Offspring Adipogenic Potential and Condition Adult Obesity Resistance.

Rudolph MC, Jackman MR, Presby DM, Houck JA, Webb PG, Johnson GC, Soderborg TK, de la Houssaye BA, Yang IV, Friedman JE, MacLean PS.

Diabetes. 2018 Apr;67(4):651-661. doi: 10.2337/db17-0890. Epub 2017 Nov 14.

PMID:
29138256
9.

Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants.

Boyle KE, Patinkin ZW, Shapiro ALB, Bader C, Vanderlinden L, Kechris K, Janssen RC, Ford RJ, Smith BK, Steinberg GR, Davidson EJ, Yang IV, Dabelea D, Friedman JE.

Mol Metab. 2017 Nov;6(11):1503-1516. doi: 10.1016/j.molmet.2017.08.012. Epub 2017 Sep 1.

10.

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

Allen RJ, Porte J, Braybrooke R, Flores C, Fingerlin TE, Oldham JM, Guillen-Guio B, Ma SF, Okamoto T, John AE, Obeidat M, Yang IV, Henry A, Hubbard RB, Navaratnam V, Saini G, Thompson N, Booth HL, Hart SP, Hill MR, Hirani N, Maher TM, McAnulty RJ, Millar AB, Molyneaux PL, Parfrey H, Rassl DM, Whyte MKB, Fahy WA, Marshall RP, Oballa E, Bossé Y, Nickle DC, Sin DD, Timens W, Shrine N, Sayers I, Hall IP, Noth I, Schwartz DA, Tobin MD, Wain LV, Jenkins RG.

Lancet Respir Med. 2017 Nov;5(11):869-880. doi: 10.1016/S2213-2600(17)30387-9. Epub 2017 Oct 20.

11.

Application of "Omics" and Systems Biology to Sarcoidosis Research.

Crouser ED, Fingerlin TE, Yang IV, Maier LA, Nana-Sinkam P, Collman RG, Kaminski N.

Ann Am Thorac Soc. 2017 Dec;14(Supplement_6):S445-S451. doi: 10.1513/AnnalsATS.201707-567OT.

PMID:
29053026
12.

Association between gestational diabetes mellitus exposure and childhood adiposity is not substantially explained by offspring genetic risk of obesity.

Raghavan S, Zhang W, Yang IV, Lange LA, Lange EM, Fingerlin TE, Dabelea D.

Diabet Med. 2017 Dec;34(12):1696-1700. doi: 10.1111/dme.13529.

PMID:
29048747
13.

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.

Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard EG, Bustamante M, Chatzi L, Cheng Munthe-Kaas M, Corpeleijn E, Czamara D, Dabelea D, Davey Smith G, De Boever P, Duijts L, Dwyer T, Eng C, Eskenazi B, Everson TM, Falahi F, Fallin MD, Farchi S, Fernandez MF, Gao L, Gaunt TR, Ghantous A, Gillman MW, Gonseth S, Grote V, Gruzieva O, Håberg SE, Herceg Z, Hivert MF, Holland N, Holloway JW, Hoyo C, Hu D, Huang RC, Huen K, Järvelin MR, Jima DD, Just AC, Karagas MR, Karlsson R, Karmaus W, Kechris KJ, Kere J, Kogevinas M, Koletzko B, Koppelman GH, Küpers LK, Ladd-Acosta C, Lahti J, Lambrechts N, Langie SAS, Lie RT, Liu AH, Magnus MC, Magnus P, Maguire RL, Marsit CJ, McArdle W, Melén E, Melton P, Murphy SK, Nawrot TS, Nisticò L, Nohr EA, Nordlund B, Nystad W, Oh SS, Oken E, Page CM, Perron P, Pershagen G, Pizzi C, Plusquin M, Raikkonen K, Reese SE, Reischl E, Richiardi L, Ring S, Roy RP, Rzehak P, Schoeters G, Schwartz DA, Sebert S, Snieder H, Sørensen TIA, Starling AP, Sunyer J, Taylor JA, Tiemeier H, Ullemar V, Vafeiadi M, Van Ijzendoorn MH, Vonk JM, Vriens A, Vrijheid M, Wang P, Wiemels JL, Wilcox AJ, Wright RJ, Xu CJ, Xu Z, Yang IV, Yousefi P, Zhang H, Zhang W, Zhao S, Agha G, Relton CL, Jaddoe VWV, London SJ.

Int J Epidemiol. 2018 Feb 1;47(1):22-23u. doi: 10.1093/ije/dyx190. No abstract available.

14.

The Plasma Concentration of MUC5B Is Associated with Clinical Outcomes in Paraquat-poisoned Patients.

Monte AA, Sun H, Rapp-Olsson AM, Mohamed F, Gawarammana I, Buckley NA, Evans CM, Yang IV, Schwartz DA.

Am J Respir Crit Care Med. 2018 Mar 1;197(5):663-665. doi: 10.1164/rccm.201705-0866LE. No abstract available.

PMID:
28719757
15.

The environment, epigenome, and asthma.

Yang IV, Lozupone CA, Schwartz DA.

J Allergy Clin Immunol. 2017 Jul;140(1):14-23. doi: 10.1016/j.jaci.2017.05.011. Review.

PMID:
28673400
16.

Forkhead box protein 3 demethylation is associated with tolerance induction in peanut-induced intestinal allergy.

Wang M, Yang IV, Davidson EJ, Joetham A, Takeda K, O'Connor BP, Gelfand EW.

J Allergy Clin Immunol. 2018 Feb;141(2):659-670.e2. doi: 10.1016/j.jaci.2017.04.020. Epub 2017 May 4.

PMID:
28479331
17.

Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.

Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, Herbstman J, Holland N, LaSalle JM, Schmidt R, Yousefi P, Perera F, Joubert BR, Wiemels J, Taylor M, Yang IV, Chen R, Hew KM, Freeland DM, Miller R, Murphy SK.

Environ Health Perspect. 2017 Apr;125(4):511-526. doi: 10.1289/EHP595. Epub 2017 Mar 31.

18.

The Nasal Methylome: A Key to Understanding Allergic Asthma.

Yang IV, Richards A, Davidson EJ, Stevens AD, Kolakowski CA, Martin RJ, Schwartz DA.

Am J Respir Crit Care Med. 2017 Mar 15;195(6):829-831. doi: 10.1164/rccm.201608-1558LE. No abstract available.

19.

Regulation of MUC5B Expression in Idiopathic Pulmonary Fibrosis.

Helling BA, Gerber AN, Kadiyala V, Sasse SK, Pedersen BS, Sparks L, Nakano Y, Okamoto T, Evans CM, Yang IV, Schwartz DA.

Am J Respir Cell Mol Biol. 2017 Jul;57(1):91-99. doi: 10.1165/rcmb.2017-0046OC.

PMID:
28272906
20.

The nasal methylome and childhood atopic asthma.

Yang IV, Pedersen BS, Liu AH, O'Connor GT, Pillai D, Kattan M, Misiak RT, Gruchalla R, Szefler SJ, Khurana Hershey GK, Kercsmar C, Richards A, Stevens AD, Kolakowski CA, Makhija M, Sorkness CA, Krouse RZ, Visness C, Davidson EJ, Hennessy CE, Martin RJ, Togias A, Busse WW, Schwartz DA.

J Allergy Clin Immunol. 2017 May;139(5):1478-1488. doi: 10.1016/j.jaci.2016.07.036. Epub 2016 Oct 13.

PMID:
27745942
21.

Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways.

Evans CM, Fingerlin TE, Schwarz MI, Lynch D, Kurche J, Warg L, Yang IV, Schwartz DA.

Physiol Rev. 2016 Oct;96(4):1567-91. doi: 10.1152/physrev.00004.2016. Review.

22.

Novel Innate Immune Genes Regulating the Macrophage Response to Gram Positive Bacteria.

Alper S, Warg LA, De Arras L, Flatley BR, Davidson EJ, Adams J, Smith K, Wohlford-Lenane CL, McCray PB Jr, Pedersen BS, Schwartz DA, Yang IV.

Genetics. 2016 Sep;204(1):327-36. doi: 10.1534/genetics.115.185314. Epub 2016 Jun 29.

23.

Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia.

Fingerlin TE, Zhang W, Yang IV, Ainsworth HC, Russell PH, Blumhagen RZ, Schwarz MI, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch DA, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Murphy E, Smith K, McKean D, Pedersen BS, Talbert J, Powers J, Markin CR, Beckman KB, Lathrop M, Freed B, Langefeld CD, Schwartz DA.

BMC Genet. 2016 Jun 7;17(1):74. doi: 10.1186/s12863-016-0377-2.

24.

DNA Methylation Changes in Nasal Epithelia Are Associated with Allergic Asthma in the Inner City.

Yang IV, Pedersen BS, Liu AH, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Gergen P, Togias A, Busse WW, Schwartz DA.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S99-S100. doi: 10.1513/AnnalsATS.201510-657MG. No abstract available.

25.

MUC5B Promoter Variant rs35705950 Affects MUC5B Expression in the Distal Airways in Idiopathic Pulmonary Fibrosis.

Nakano Y, Yang IV, Walts AD, Watson AM, Helling BA, Fletcher AA, Lara AR, Schwarz MI, Evans CM, Schwartz DA.

Am J Respir Crit Care Med. 2016 Feb 15;193(4):464-6. doi: 10.1164/rccm.201509-1872LE. No abstract available.

26.

Desmoplakin Variants Are Associated with Idiopathic Pulmonary Fibrosis.

Mathai SK, Pedersen BS, Smith K, Russell P, Schwarz MI, Brown KK, Steele MP, Loyd JE, Crapo JD, Silverman EK, Nickerson D, Fingerlin TE, Yang IV, Schwartz DA.

Am J Respir Crit Care Med. 2016 May 15;193(10):1151-60. doi: 10.1164/rccm.201509-1863OC.

27.

In Utero Cigarette Smoke Affects Allergic Airway Disease But Does Not Alter the Lung Methylome.

Eyring KR, Pedersen BS, Yang IV, Schwartz DA.

PLoS One. 2015 Dec 7;10(12):e0144087. doi: 10.1371/journal.pone.0144087. eCollection 2015.

28.

MUC5B and Idiopathic Pulmonary Fibrosis.

Yang IV, Fingerlin TE, Evans CM, Schwarz MI, Schwartz DA.

Ann Am Thorac Soc. 2015 Nov;12 Suppl 2:S193-9. doi: 10.1513/AnnalsATS.201503-110AW.

29.

Unique DNA Methylation Patterns in Offspring of Hypertensive Pregnancy.

Julian CG, Pedersen BS, Salmon CS, Yang IV, Gonzales M, Vargas E, Moore LG, Schwartz DA.

Clin Transl Sci. 2015 Dec;8(6):740-5. doi: 10.1111/cts.12346. Epub 2015 Nov 6.

30.

Relationship between gene expression and lung function in Idiopathic Interstitial Pneumonias.

Steele MP, Luna LG, Coldren CD, Murphy E, Hennessy CE, Heinz D, Evans CM, Groshong S, Cool C, Cosgrove GP, Brown KK, Fingerlin TE, Schwarz MI, Schwartz DA, Yang IV.

BMC Genomics. 2015 Oct 26;16:869. doi: 10.1186/s12864-015-2102-3.

31.

Incorporating genetics into the identification and treatment of Idiopathic Pulmonary Fibrosis.

Mathai SK, Yang IV, Schwarz MI, Schwartz DA.

BMC Med. 2015 Sep 24;13:191. doi: 10.1186/s12916-015-0434-0.

32.

Epigenetics in lung fibrosis: from pathobiology to treatment perspective.

Helling BA, Yang IV.

Curr Opin Pulm Med. 2015 Sep;21(5):454-62. doi: 10.1097/MCP.0000000000000191. Review.

33.

DNA methylation and childhood asthma in the inner city.

Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA.

J Allergy Clin Immunol. 2015 Jul;136(1):69-80. doi: 10.1016/j.jaci.2015.01.025. Epub 2015 Mar 11.

34.

An epigenome-wide association study of total serum immunoglobulin E concentration.

Liang L, Willis-Owen SAG, Laprise C, Wong KCC, Davies GA, Hudson TJ, Binia A, Hopkin JM, Yang IV, Grundberg E, Busche S, Hudson M, Rönnblom L, Pastinen TM, Schwartz DA, Lathrop GM, Moffatt MF, Cookson WOCM.

Nature. 2015 Apr 30;520(7549):670-674. doi: 10.1038/nature14125. Epub 2015 Feb 18.

35.

AKT network of genes and impaired myocardial contractility during murine acute Chagasic myocarditis.

Henao-Martínez AF, Agler AH, Watson AM, Hennessy C, Davidson E, Demos-Davies K, McKinsey TA, Wilson M, Schwartz DA, Yang IV.

Am J Trop Med Hyg. 2015 Mar;92(3):523-9. doi: 10.4269/ajtmh.14-0433. Epub 2015 Jan 12.

36.

Assessment of microRNA differential expression and detection in multiplexed small RNA sequencing data.

Campbell JD, Liu G, Luo L, Xiao J, Gerrein J, Juan-Guardela B, Tedrow J, Alekseyev YO, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Schwartz DA, Kaminski N, Johnson WE, Monti S, Spira A, Beane J, Lenburg ME.

RNA. 2015 Feb;21(2):164-71. doi: 10.1261/rna.046060.114. Epub 2014 Dec 17.

37.

Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis.

Yang IV, Pedersen BS, Rabinovich E, Hennessy CE, Davidson EJ, Murphy E, Guardela BJ, Tedrow JR, Zhang Y, Singh MK, Correll M, Schwarz MI, Geraci M, Sciurba FC, Quackenbush J, Spira A, Kaminski N, Schwartz DA.

Am J Respir Crit Care Med. 2014 Dec 1;190(11):1263-72. doi: 10.1164/rccm.201408-1452OC.

38.

Familial and sporadic idiopathic pulmonary fibrosis: making the diagnosis from peripheral blood.

Meltzer EB, Barry WT, Yang IV, Brown KK, Schwarz MI, Patel H, Ashley A, Noble PW, Schwartz DA, Steele MP.

BMC Genomics. 2014 Oct 16;15:902. doi: 10.1186/1471-2164-15-902.

39.

The MUC5B promoter polymorphism is associated with idiopathic pulmonary fibrosis in a Mexican cohort but is rare among Asian ancestries.

Peljto AL, Selman M, Kim DS, Murphy E, Tucker L, Pardo A, Lee JS, Ji W, Schwarz MI, Yang IV, Schwartz DA, Fingerlin TE.

Chest. 2015 Feb;147(2):460-464. doi: 10.1378/chest.14-0867.

40.

Stanniocalcin-1 is induced by hypoxia inducible factor in rat alveolar epithelial cells.

Ito Y, Zemans R, Correll K, Yang IV, Ahmad A, Gao B, Mason RJ.

Biochem Biophys Res Commun. 2014 Oct 3;452(4):1091-7. doi: 10.1016/j.bbrc.2014.09.060. Epub 2014 Sep 22.

41.

NOS3 polymorphism, lung function, and exposure in swine operations: results of 2 studies.

Gao Z, Dosman JA, Rennie DC, Schwartz DA, Yang IV, Beach J, Senthilselvan A.

J Allergy Clin Immunol. 2014 Aug;134(2):485-8. doi: 10.1016/j.jaci.2014.04.006. Epub 2014 May 24. No abstract available.

PMID:
24865140
42.

Epigenetics of idiopathic pulmonary fibrosis.

Yang IV, Schwartz DA.

Transl Res. 2015 Jan;165(1):48-60. doi: 10.1016/j.trsl.2014.03.011. Epub 2014 Mar 31. Review.

43.

The Toll-like receptor 4 polymorphism Asp299Gly but not Thr399Ile influences TLR4 signaling and function.

Long H, O'Connor BP, Zemans RL, Zhou X, Yang IV, Schwartz DA.

PLoS One. 2014 Apr 2;9(4):e93550. doi: 10.1371/journal.pone.0093550. eCollection 2014.

44.

Muc5b is required for airway defence.

Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM.

Nature. 2014 Jan 16;505(7483):412-6. doi: 10.1038/nature12807. Epub 2013 Dec 8.

45.

Inhibition of peroxisome proliferator-activated receptor γ: a potential link between chronic maternal hypoxia and impaired fetal growth.

Julian CG, Yang IV, Browne VA, Vargas E, Rodriguez C, Pedersen BS, Moore LG, Schwartz DA.

FASEB J. 2014 Mar;28(3):1268-79. doi: 10.1096/fj.13-239749. Epub 2013 Dec 4.

46.

Functional polymorphisms in the gene encoding macrophage migration inhibitory factor are associated with Gram-negative bacteremia in older adults.

Das R, Subrahmanyan L, Yang IV, van Duin D, Levy R, Piecychna M, Leng L, Montgomery RR, Shaw A, Schwartz DA, Bucala R.

J Infect Dis. 2014 Mar 1;209(5):764-8. doi: 10.1093/infdis/jit571. Epub 2013 Oct 24.

47.

CruzDB: software for annotation of genomic intervals with UCSC genome-browser database.

Pedersen BS, Yang IV, De S.

Bioinformatics. 2013 Dec 1;29(23):3003-6. doi: 10.1093/bioinformatics/btt534. Epub 2013 Sep 12.

48.

Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis.

Yang IV, Coldren CD, Leach SM, Seibold MA, Murphy E, Lin J, Rosen R, Neidermyer AJ, McKean DF, Groshong SD, Cool C, Cosgrove GP, Lynch DA, Brown KK, Schwarz MI, Fingerlin TE, Schwartz DA.

Thorax. 2013 Dec;68(12):1114-21. doi: 10.1136/thoraxjnl-2012-202943. Epub 2013 Jun 19.

PMID:
23783374
49.

Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin.

Lai PS, Hofmann O, Baron RM, Cernadas M, Meng QR, Bresler HS, Brass DM, Yang IV, Schwartz DA, Christiani DC, Hide W.

PLoS One. 2013 May 13;8(5):e62910. doi: 10.1371/journal.pone.0062910. Print 2013.

50.

Role of macrophage receptor with collagenous structure in innate immune tolerance.

Jing J, Yang IV, Hui L, Patel JA, Evans CM, Prikeris R, Kobzik L, O'Connor BP, Schwartz DA.

J Immunol. 2013 Jun 15;190(12):6360-7. doi: 10.4049/jimmunol.1202942. Epub 2013 May 10.

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