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Items: 1 to 50 of 436

1.

Neuropeptide oxytocin enhances μ opioid receptor signaling as a positive allosteric modulator.

Meguro Y, Miyano K, Hirayama S, Yoshida Y, Ishibashi N, Ogino T, Fujii Y, Manabe S, Eto M, Nonaka M, Fujii H, Ueta Y, Narita M, Sata N, Yada T, Uezono Y.

J Pharmacol Sci. 2018 Apr 11. pii: S1347-8613(18)30065-3. doi: 10.1016/j.jphs.2018.04.002. [Epub ahead of print]

2.

Protective role of AgRP neuron's PDK1 against salt-induced hypertension.

Zhang B, Nakata M, Lu M, Nakae J, Okada T, Ogawa W, Yada T.

Biochem Biophys Res Commun. 2018 Jun 12;500(4):910-916. doi: 10.1016/j.bbrc.2018.04.192. Epub 2018 Apr 30.

PMID:
29705701
3.

Short-chain fatty acids suppress food intake by activating vagal afferent neurons.

Goswami C, Iwasaki Y, Yada T.

J Nutr Biochem. 2018 Mar 17;57:130-135. doi: 10.1016/j.jnutbio.2018.03.009. [Epub ahead of print]

PMID:
29702431
4.
5.

Identification of Minimal p53 Promoter Region Regulated by MALAT1 in Human Lung Adenocarcinoma Cells.

Tano K, Onoguchi-Mizutani R, Yeasmin F, Uchiumi F, Suzuki Y, Yada T, Akimitsu N.

Front Genet. 2018 Mar 26;8:208. doi: 10.3389/fgene.2017.00208. eCollection 2017.

6.

A multicenter, randomized controlled trial comparing the identification rate of stigmata of recent hemorrhage and rebleeding rate between early and elective colonoscopy in outpatient-onset acute lower gastrointestinal bleeding: study protocol for a randomized controlled trial.

Niikura R, Nagata N, Yamada A, Doyama H, Shiratori Y, Nishida T, Kiyotoki S, Yada T, Fujita T, Sumiyoshi T, Hasatani K, Mikami T, Honda T, Mabe K, Hara K, Yamamoto K, Takeda M, Takata M, Tanaka M, Shinozaki T, Fujishiro M, Koike K.

Trials. 2018 Apr 3;19(1):214. doi: 10.1186/s13063-018-2558-y.

7.

GLP-1 receptor agonist liraglutide exerts central action to induce β-cell proliferation through medulla to vagal pathway in mice.

Kumari P, Nakata M, Zhang BY, Otgon-Uul Z, Yada T.

Biochem Biophys Res Commun. 2018 May 15;499(3):618-625. doi: 10.1016/j.bbrc.2018.03.199. Epub 2018 Apr 9.

PMID:
29601817
8.

Weaning stage hyperglycemia induces glucose-insensitivity in arcuate POMC neurons and hyperphagia in type 2 diabetic GK rats.

Ando A, Gantulga D, Nakata M, Maekawa F, Dezaki K, Ishibashi S, Yada T.

Neuropeptides. 2018 Apr;68:49-56. doi: 10.1016/j.npep.2018.02.001. Epub 2018 Feb 6.

9.

Activation of AMPK-Regulated CRH Neurons in the PVH is Sufficient and Necessary to Induce Dietary Preference for Carbohydrate over Fat.

Okamoto S, Sato T, Tateyama M, Kageyama H, Maejima Y, Nakata M, Hirako S, Matsuo T, Kyaw S, Shiuchi T, Toda C, Sedbazar U, Saito K, Asgar NF, Zhang B, Yokota S, Kobayashi K, Foufelle F, Ferré P, Nakazato M, Masuzaki H, Shioda S, Yada T, Kahn BB, Minokoshi Y.

Cell Rep. 2018 Jan 16;22(3):706-721. doi: 10.1016/j.celrep.2017.11.102.

10.

GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose.

Iwasaki Y, Sendo M, Dezaki K, Hira T, Sato T, Nakata M, Goswami C, Aoki R, Arai T, Kumari P, Hayakawa M, Masuda C, Okada T, Hara H, Drucker DJ, Yamada Y, Tokuda M, Yada T.

Nat Commun. 2018 Jan 9;9(1):113. doi: 10.1038/s41467-017-02488-y.

11.

Molecular biology and functional genomics of immune-endocrine interactions in the Japanese eel, Anguilla japonica.

Yada T, Mekuchi M, Ojima N.

Gen Comp Endocrinol. 2018 Feb 1;257:272-279. doi: 10.1016/j.ygcen.2017.11.001. Epub 2017 Nov 3.

PMID:
29108728
12.

The effects of adjunctive intranasal oxytocin in patients with schizophrenia.

Ota M, Yoshida S, Nakata M, Yada T, Kunugi H.

Postgrad Med. 2018 Jan;130(1):122-128. doi: 10.1080/00325481.2018.1398592. Epub 2017 Nov 6.

PMID:
29105546
13.

Inhibition of Y1 receptor signaling improves islet transplant outcome.

Loh K, Shi YC, Walters S, Bensellam M, Lee K, Dezaki K, Nakata M, Ip CK, Chan JY, Gurzov EN, Thomas HE, Waibel M, Cantley J, Kay TW, Yada T, Laybutt DR, Grey ST, Herzog H.

Nat Commun. 2017 Sep 8;8(1):490. doi: 10.1038/s41467-017-00624-2.

14.

Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons.

Suyama S, Ralevski A, Liu ZW, Dietrich MO, Yada T, Simonds SE, Cowley MA, Gao XB, Diano S, Horvath TL.

Elife. 2017 Aug 1;6. pii: e25755. doi: 10.7554/eLife.25755.

15.

Involvement of thermosensitive TRP channels in energy metabolism.

Uchida K, Dezaki K, Yoneshiro T, Watanabe T, Yamazaki J, Saito M, Yada T, Tominaga M, Iwasaki Y.

J Physiol Sci. 2017 Sep;67(5):549-560. doi: 10.1007/s12576-017-0552-x. Epub 2017 Jun 27. Review.

PMID:
28656459
16.

Glucagon-like peptide-1 and insulin synergistically activate vagal afferent neurons.

Iwasaki Y, Goswami C, Yada T.

Neuropeptides. 2017 Oct;65:77-82. doi: 10.1016/j.npep.2017.05.003. Epub 2017 May 25.

PMID:
28624122
17.

Adiponectin at physiological level glucose-independently enhances inhibitory postsynaptic current onto NPY neurons in the hypothalamic arcuate nucleus.

Suyama S, Lei W, Kubota N, Kadowaki T, Yada T.

Neuropeptides. 2017 Oct;65:1-9. doi: 10.1016/j.npep.2017.03.003. Epub 2017 Mar 22.

PMID:
28606559
18.

A new computational method to predict transcriptional activity of a DNA sequence from diverse datasets of massively parallel reporter assays.

Liu Y, Irie T, Yada T, Suzuki Y.

Nucleic Acids Res. 2017 Jul 27;45(13):e124. doi: 10.1093/nar/gkx396.

19.

Complexity of Stomach-Brain Interaction Induced by Molecular Hydrogen in Parkinson's Disease Model Mice.

Yoshii Y, Inoue T, Uemura Y, Iwasaki Y, Yada T, Nakabeppu Y, Noda M.

Neurochem Res. 2017 Sep;42(9):2658-2665. doi: 10.1007/s11064-017-2281-1. Epub 2017 May 2.

PMID:
28462451
20.

PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis.

Sasanuma H, Nakata M, Parmila K, Nakae J, Yada T.

Mol Metab. 2017 Feb 17;6(5):428-439. doi: 10.1016/j.molmet.2017.02.003. eCollection 2017 May.

21.

Estimating optimal sparseness of developmental gene networks using a semi-quantitative model.

Ichinose N, Yada T, Wada H.

PLoS One. 2017 Apr 21;12(4):e0176492. doi: 10.1371/journal.pone.0176492. eCollection 2017.

22.

Fibroblast growth factor 21, assisted by elevated glucose, activates paraventricular nucleus NUCB2/Nesfatin-1 neurons to produce satiety under fed states.

Santoso P, Nakata M, Shiizaki K, Boyang Z, Parmila K, Otgon-Uul Z, Hashimoto K, Satoh T, Mori M, Kuro-O M, Yada T.

Sci Rep. 2017 Apr 4;7:45819. doi: 10.1038/srep45819.

23.

Suprachiasmatic Vasopressin to Paraventricular Oxytocin Neurocircuit in the Hypothalamus Relays Light Reception to Inhibition of Feeding Behavior.

Santoso P, Nakata M, Ueta Y, Yada T.

Am J Physiol Endocrinol Metab. 2017 Feb 7:ajpendo003382016. doi: 10.1152/ajpendo.00338.2016. [Epub ahead of print]

PMID:
28174180
24.

High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance.

Nakata M, Zhang B, Yang Y, Okada T, Shintani N, Hashimoto H, Yada T.

J Diabetes Res. 2016;2016:9321395. doi: 10.1155/2016/9321395. Epub 2016 Dec 1.

25.

Endogenous α2A-Adrenoceptor-Operated Sympathoadrenergic Tones Attenuate Insulin Secretion via cAMP/TRPM2 Signaling.

Ito K, Dezaki K, Yoshida M, Yamada H, Miura R, Rita RS, Ookawara S, Tabei K, Kawakami M, Hara K, Morishita Y, Yada T, Kakei M.

Diabetes. 2017 Mar;66(3):699-709. doi: 10.2337/db16-1166. Epub 2016 Dec 27.

26.

Characteristics of gastric cancer in negative test of serum anti-Helicobacter pylori antibody and pepsinogen test: a multicenter study.

Kiso M, Yoshihara M, Ito M, Inoue K, Kato K, Nakajima S, Mabe K, Kobayashi M, Uemura N, Yada T, Oka M, Kawai T, Boda T, Kotachi T, Masuda K, Tanaka S, Chayama K.

Gastric Cancer. 2017 Sep;20(5):764-771. doi: 10.1007/s10120-016-0682-5. Epub 2016 Dec 26.

PMID:
28025702
27.

AAV-mediated IL-10 gene transfer counteracts inflammation in the hypothalamic arcuate nucleus and obesity induced by high-fat diet.

Nakata M, Yamamoto S, Okada T, Yada T.

Neuropeptides. 2017 Apr;62:87-92. doi: 10.1016/j.npep.2016.11.009. Epub 2016 Dec 6.

PMID:
27939689
28.

Sweet Taste Receptor Serves to Activate Glucose- and Leptin-Responsive Neurons in the Hypothalamic Arcuate Nucleus and Participates in Glucose Responsiveness.

Kohno D, Koike M, Ninomiya Y, Kojima I, Kitamura T, Yada T.

Front Neurosci. 2016 Nov 8;10:502. eCollection 2016.

29.

Glucose and GTP-binding protein-coupled receptor cooperatively regulate transient receptor potential-channels to stimulate insulin secretion [Review].

Kakei M, Yoshida M, Dezaki K, Ito K, Yamada H, Funazaki S, Kawakami M, Sugawara H, Yada T.

Endocr J. 2016 Oct 29;63(10):867-876. Epub 2016 Jul 17. Review.

30.

Caspase-1 deficiency promotes high-fat diet-induced adipose tissue inflammation and the development of obesity.

Kimura H, Karasawa T, Usui F, Kawashima A, Endo Y, Kobayashi M, Sadatomo A, Nakamura J, Iwasaki Y, Yada T, Tsutsui H, Kasahara T, Takahashi M.

Am J Physiol Endocrinol Metab. 2016 Nov 1;311(5):E881-E890. doi: 10.1152/ajpendo.00174.2016. Epub 2016 Oct 4.

31.

Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin1.

Fujitsuka N, Asakawa A, Morinaga A, Amitani MS, Amitani H, Katsuura G, Sawada Y, Sudo Y, Uezono Y, Mochiki E, Sakata I, Sakai T, Hanazaki K, Yada T, Yakabi K, Sakuma E, Ueki T, Niijima A, Nakagawa K, Okubo N, Takeda H, Asaka M, Inui A.

Mol Psychiatry. 2016 Nov;21(11):1613-1623. doi: 10.1038/mp.2015.220. Epub 2016 Feb 2.

32.

Insulin-like growth factor 1 regulation of proliferation and differentiation of Xenopus laevis myogenic cells in vitro.

Miyata S, Yada T, Ishikawa N, Taheruzzaman K, Hara R, Matsuzaki T, Nishikawa A.

In Vitro Cell Dev Biol Anim. 2017 Mar;53(3):231-247. doi: 10.1007/s11626-016-0099-9. Epub 2016 Oct 3.

PMID:
27699652
33.

Choosing the right protein A affinity chromatography media can remove aggregates efficiently.

Yada T, Nonaka K, Yabuta M, Yoshimoto N, Yamamoto S.

Biotechnol J. 2017 Jan;12(1). doi: 10.1002/biot.201600427. Epub 2016 Oct 10.

PMID:
27660109
34.
35.

Glucose level determines excitatory or inhibitory effects of adiponectin on arcuate POMC neuron activity and feeding.

Suyama S, Maekawa F, Maejima Y, Kubota N, Kadowaki T, Yada T.

Sci Rep. 2016 Aug 9;6:30796. doi: 10.1038/srep30796.

36.

A case of intraductal papillary mucinous neoplasm with high serum pepsinogen II level.

Ito K, Koizuka H, Suzuki K, Okubo K, Aoki Y, Yada T, Akazawa N, Aoyanagi N, Ishida T, Uemura N.

Nihon Shokakibyo Gakkai Zasshi. 2016 Aug;113(8):1416-24. doi: 10.11405/nisshoshi.113.1416. Review. Japanese.

PMID:
27498939
37.

Neural effects of gut- and brain-derived glucagon-like peptide-1 and its receptor agonist.

Katsurada K, Yada T.

J Diabetes Investig. 2016 Apr;7 Suppl 1:64-9. doi: 10.1111/jdi.12464. Epub 2016 Mar 31. Review.

38.

Potentiation of Glucose-stimulated Insulin Secretion by the GPR40-PLC-TRPC Pathway in Pancreatic β-Cells.

Yamada H, Yoshida M, Ito K, Dezaki K, Yada T, Ishikawa SE, Kakei M.

Sci Rep. 2016 May 16;6:25912. doi: 10.1038/srep25912.

39.

Paraventricular NUCB2/Nesfatin-1 Supports Oxytocin and Vasopressin Neurons to Control Feeding Behavior and Fluid Balance in Male Mice.

Nakata M, Gantulga D, Santoso P, Zhang B, Masuda C, Mori M, Okada T, Yada T.

Endocrinology. 2016 Jun;157(6):2322-32. doi: 10.1210/en.2015-2082. Epub 2016 Apr 22.

PMID:
27105386
40.

Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice.

Li E, Nakata M, Shinozaki A, Yang Y, Zhang B, Yada T.

Endocr J. 2016 Jul 30;63(7):611-9. doi: 10.1507/endocrj.EJ16-0164. Epub 2016 Apr 19.

41.

Total gastrectomy-induced reductions in food intake and weight are counteracted by rikkunshito by attenuating glucagon-like peptide-1 elevation in rats.

Taguchi M, Dezaki K, Koizumi M, Kurashina K, Hosoya Y, Lefor AK, Sata N, Yada T.

Surgery. 2016 May;159(5):1342-50. doi: 10.1016/j.surg.2015.12.003. Epub 2016 Jan 13.

PMID:
26775072
42.

Epigenetic regulation of proliferation and invasion in hepatocellular carcinoma cells by CBP/p300 histone acetyltransferase activity.

Inagaki Y, Shiraki K, Sugimoto K, Yada T, Tameda M, Ogura S, Yamamoto N, Takei Y, Ito M.

Int J Oncol. 2016 Feb;48(2):533-40. doi: 10.3892/ijo.2015.3288. Epub 2015 Dec 11.

PMID:
26676548
43.

Immunoproteasome subunit LMP7 Deficiency Improves Obesity and Metabolic Disorders.

Kimura H, Usui F, Karasawa T, Kawashima A, Shirasuna K, Inoue Y, Komada T, Kobayashi M, Mizushina Y, Kasahara T, Suzuki K, Iwasaki Y, Yada T, Caturegli P, Takahashi M.

Sci Rep. 2015 Oct 30;5:15883. doi: 10.1038/srep15883.

44.

Different gene expression profiles between normal and thermally selected strains of rainbow trout, Oncorhynchus mykiss, as revealed by comprehensive transcriptome analysis.

Tan E, Kinoshita S, Suzuki Y, Ineno T, Tamaki K, Kera A, Muto K, Yada T, Kitamura S, Asakawa S, Watabe S.

Gene. 2016 Feb 1;576(2 Pt 1):637-43. doi: 10.1016/j.gene.2015.10.028. Epub 2015 Oct 22.

PMID:
26476292
45.

IL-10 gene transfer upregulates arcuate POMC and ameliorates hyperphagia, obesity and diabetes by substituting for leptin.

Nakata M, Yamamoto S, Okada T, Gantulga D, Okano H, Ozawa K, Yada T.

Int J Obes (Lond). 2016 Mar;40(3):425-33. doi: 10.1038/ijo.2015.201. Epub 2015 Oct 5.

PMID:
26435324
46.

The β-cell GHSR and downstream cAMP/TRPM2 signaling account for insulinostatic and glycemic effects of ghrelin.

Kurashina T, Dezaki K, Yoshida M, Sukma Rita R, Ito K, Taguchi M, Miura R, Tominaga M, Ishibashi S, Kakei M, Yada T.

Sci Rep. 2015 Sep 15;5:14041. doi: 10.1038/srep14041.

47.

Fasted/fed states regulate postsynaptic hub protein DYNLL2 and glutamatergic transmission in oxytocin neurons in the hypothalamic paraventricular nucleus.

Suyama S, Kodaira-Hirano M, Otgon-Uul Z, Ueta Y, Nakata M, Yada T.

Neuropeptides. 2016 Apr;56:115-23. doi: 10.1016/j.npep.2015.08.008. Epub 2015 Aug 28.

PMID:
26344333
48.

N-methyl-d-aspartate receptor coagonist d-serine suppresses intake of high-preference food.

Sasaki T, Kinoshita Y, Matsui S, Kakuta S, Yokota-Hashimoto H, Kinoshita K, Iwasaki Y, Kinoshita T, Yada T, Amano N, Kitamura T.

Am J Physiol Regul Integr Comp Physiol. 2015 Sep;309(5):R561-75. doi: 10.1152/ajpregu.00083.2015. Epub 2015 Jul 8.

49.

A novel insulinotropic mechanism of whole grain-derived γ-oryzanol via the suppression of local dopamine D2 receptor signalling in mouse islet.

Kozuka C, Sunagawa S, Ueda R, Higa M, Ohshiro Y, Tanaka H, Shimizu-Okabe C, Takayama C, Matsushita M, Tsutsui M, Ishiuchi S, Nakata M, Yada T, Miyazaki JI, Oyadomari S, Shimabukuro M, Masuzaki H.

Br J Pharmacol. 2015 Jul 3. doi: 10.1111/bph.13236. [Epub ahead of print]

50.

Ghrelin counteracts insulin-induced activation of vagal afferent neurons via growth hormone secretagogue receptor.

Iwasaki Y, Dezaki K, Kumari P, Kakei M, Yada T.

Neuropeptides. 2015 Aug;52:55-60. doi: 10.1016/j.npep.2015.06.003. Epub 2015 Jun 14.

PMID:
26138507

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