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Cryo-EM structure of the RC-LH core complex from an early branching photosynthetic prokaryote.

Xin Y, Shi Y, Niu T, Wang Q, Niu W, Huang X, Ding W, Yang L, Blankenship RE, Xu X, Sun F.

Nat Commun. 2018 Apr 19;9(1):1568. doi: 10.1038/s41467-018-03881-x.


Maca polysaccharides: Extraction optimization, structural features and anti-fatigue activities.

Li Y, Xin Y, Xu F, Zheng M, Xi X, Cui X, Cao H, Guo H, Han C.

Int J Biol Macromol. 2018 Apr 14. pii: S0141-8130(17)35168-1. doi: 10.1016/j.ijbiomac.2018.04.063. [Epub ahead of print]


Phase 1 First-in-Human, Single- and Multiple-Ascending Dose, and Food Effect Studies to Assess the Safety, Tolerability, and Pharmacokinetics of Presatovir for the Treatment of Respiratory Syncytial Virus Infection.

German P, Xin Y, Chien JW, Weng W, Mackman R, Lewis SA, Meng A, Ling J, Mathias A.

J Clin Pharmacol. 2018 Apr 17. doi: 10.1002/jcph.1112. [Epub ahead of print]


Can a Framework Be Established for the Safe Use of Ketamine?

Freedman R, Brown AS, Cannon TD, Druss BG, Earls FJ, Escobar J, Hurd YL, Lewis DA, López-Jaramillo C, Luby J, Mayberg HS, Moffitt TE, Oquendo M, Perlis RH, Pine DS, Rush AJ, Tamminga CA, Tohen M, Vieta E, Wisner KL, Xin Y.

Am J Psychiatry. 2018 Apr 16:appiajp201818030290. doi: 10.1176/appi.ajp.2018.18030290. [Epub ahead of print] No abstract available.


Revisiting the developmental and cellular role of the pigmentation gene yellow in Drosophila using a tagged allele.

Hinaux H, Bachem K, Battistara M, Rossi M, Xin Y, Jaenichen R, Le Poul Y, Arnoult L, Kobler JM, Grunwald Kadow IC, Rodermund L, Prud'homme B, Gompel N.

Dev Biol. 2018 Apr 7. pii: S0012-1606(18)30094-0. doi: 10.1016/j.ydbio.2018.04.003. [Epub ahead of print]


Sorafenib-loaded polymeric micelles as passive targeting therapeutic agents for hepatocellular carcinoma therapy.

Su Y, Wang K, Li Y, Song W, Xin Y, Zhao W, Tian J, Ren L, Lu L.

Nanomedicine (Lond). 2018 Apr 9. doi: 10.2217/nnm-2018-0046. [Epub ahead of print]


Positive periodic solution for p-Laplacian neutral Rayleigh equation with singularity of attractive type.

Xin Y, Liu H, Cheng Z.

J Inequal Appl. 2018;2018(1):58. doi: 10.1186/s13660-018-1654-6. Epub 2018 Mar 14.


A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.

Abul-Husn NS, Cheng X, Li AH, Xin Y, Schurmann C, Stevis P, Liu Y, Kozlitina J, Stender S, Wood GC, Stepanchick AN, Still MD, McCarthy S, O'Dushlaine C, Packer JS, Balasubramanian S, Gosalia N, Esopi D, Kim SY, Mukherjee S, Lopez AE, Fuller ED, Penn J, Chu X, Luo JZ, Mirshahi UL, Carey DJ, Still CD, Feldman MD, Small A, Damrauer SM, Rader DJ, Zambrowicz B, Olson W, Murphy AJ, Borecki IB, Shuldiner AR, Reid JG, Overton JD, Yancopoulos GD, Hobbs HH, Cohen JC, Gottesman O, Teslovich TM, Baras A, Mirshahi T, Gromada J, Dewey FE.

N Engl J Med. 2018 Mar 22;378(12):1096-1106. doi: 10.1056/NEJMoa1712191.


Arthrobacter ruber sp. nov., isolated from glacier ice.

Liu Q, Xin YH, Chen XL, Liu HC, Zhou YG, Chen WX.

Int J Syst Evol Microbiol. 2018 Mar 21. doi: 10.1099/ijsem.0.002719. [Epub ahead of print]


Development of a tetra-primer ARMS-PCR for detecting the E198A SNP in the isotype-1 β-tubulin gene of Haemonchus contortus populations in China.

Zongze Z, Xin Y, Awais AA, Weiqiang L, Chunqun W, Di W, Yanqin Z, Junlong Z, Rui F, Min H.

Vet Parasitol. 2018 Mar 15;252:127-130. doi: 10.1016/j.vetpar.2018.01.021. Epub 2018 Jan 31.


Glucagon contributes to liver zonation.

Cheng X, Kim SY, Okamoto H, Xin Y, Yancopoulos GD, Murphy AJ, Gromada J.

Proc Natl Acad Sci U S A. 2018 Mar 19. pii: 201721403. doi: 10.1073/pnas.1721403115. [Epub ahead of print]


Nimotuzumab enhances the sensitivity of non-small cell lung cancer cells to tumor necrosis factor-α by inhibiting the nuclear factor-кB signaling pathway.

Zhu J, Xin Y, Liu X, Wang Y, Liu Y.

Exp Ther Med. 2018 Apr;15(4):3345-3351. doi: 10.3892/etm.2018.5856. Epub 2018 Feb 12.


Meta-analysis of whole-brain radiotherapy plus temozolomide compared with whole-brain radiotherapy for the treatment of brain metastases from non-small-cell lung cancer.

Xin Y, Guo W, Yang CS, Huang Q, Zhang P, Zhang LZ, Jiang G.

Cancer Med. 2018 Mar 7. doi: 10.1002/cam4.1306. [Epub ahead of print]


Synthesis and Pharmacological Evaluation of 2,3-Diphenyl Acrylonitrile Bearing Halogen as Selective Anticancer Agents.

Li JJ, Ma J, Xin YB, Quan ZS, Tian YS.

Chem Biol Drug Des. 2018 Mar 8. doi: 10.1111/cbdd.13180. [Epub ahead of print]


MiRNA-491-5p inhibits cell proliferation, invasion and migration via targeting JMJD2B and serves as a potential biomarker in gastric cancer.

Zhang J, Ren J, Hao S, Ma F, Xin Y, Jia W, Sun Y, Liu Z, Yu H, Jia J, Li W.

Am J Transl Res. 2018 Feb 15;10(2):525-534. eCollection 2018.


Proteome analysis of differential protein expression in porcine alveolar macrophages regulated by porcine reproductive and respiratory syndrome virus nsp1β protein.

Xin Y, Wang D, Huang M, Yu J, Fang L, Xiao S.

Virus Genes. 2018 Mar 5. doi: 10.1007/s11262-018-1547-2. [Epub ahead of print]


Overexpression of long non-coding RNA KCNQ1OT1 is related to good prognosis via inhibiting cell proliferation in non-small cell lung cancer.

Sun X, Xin Y, Wang M, Li S, Miao S, Xuan Y, Wang Y, Lu T, Liu J, Jiao W.

Thorac Cancer. 2018 Mar 5. doi: 10.1111/1759-7714.12599. [Epub ahead of print]


Shox2: The Role in Differentiation and Development of Cardiac Conduction System.

Hu W, Xin Y, Zhao Y, Hu J.

Tohoku J Exp Med. 2018 Mar;244(3):177-186. doi: 10.1620/tjem.244.177.


An Image Auxiliary Method for Quantitative Analysis of Laser-Induced Breakdown Spectroscopy.

Zhang P, Sun L, Yu H, Zeng P, Qi L, Xin Y.

Anal Chem. 2018 Apr 3;90(7):4686-4694. doi: 10.1021/acs.analchem.7b05284. Epub 2018 Mar 13.


One-Pot Synthetic Approach toward Porphyrinatozinc and Heavy-Atom Involved Zr-NMOF and Its Application in Photodynamic Therapy.

Zhou LL, Guan Q, Li YA, Zhou Y, Xin YB, Dong YB.

Inorg Chem. 2018 Mar 19;57(6):3169-3176. doi: 10.1021/acs.inorgchem.7b03204. Epub 2018 Feb 28.


Prevalence and correlates of depressive disorders in people with Type 2 diabetes: results from the International Prevalence and Treatment of Diabetes and Depression (INTERPRET-DD) study, a collaborative study carried out in 14 countries.

Lloyd CE, Nouwen A, Sartorius N, Ahmed HU, Alvarez A, Bahendeka S, Basangwa D, Bobrov AE, Boden S, Bulgari V, Burti L, Chaturvedi SK, Cimino LC, Gaebel W, de Girolamo G, Gondek TM, de Braude MG, Guntupalli A, Heinze MG, Ji L, Hong X, Khan A, Kiejna A, Kokoszka A, Kamala T, Lalic NM, Lecic Tosevski D, Mankovsky B, Li M, Musau A, Müssig K, Ndetei D, Rabbani G, Srikanta SS, Starostina EG, Shevchuk M, Taj R, Vukovic O, Wölwer W, Xin Y.

Diabet Med. 2018 Feb 25. doi: 10.1111/dme.13611. [Epub ahead of print]


Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach.

Pourfathi M, Cereda M, Chatterjee S, Xin Y, Kadlecek S, Duncan I, Hamedani H, Siddiqui S, Profka H, Ehrich J, Ruppert K, Rizi RR.

Sci Rep. 2018 Feb 23;8(1):3525. doi: 10.1038/s41598-018-21901-0.


Helicobacter pylori Type IV Secretion System and Its Adhesin Subunit, CagL, Mediate Potent Inflammatory Responses in Primary Human Endothelial Cells.

Tafreshi M, Guan J, Gorrell RJ, Chew N, Xin Y, Deswaerte V, Rohde M, Daly RJ, Peek RM Jr., Jenkins BJ, Davies EM, Kwok T.

Front Cell Infect Microbiol. 2018 Feb 6;8:22. doi: 10.3389/fcimb.2018.00022. eCollection 2018.


Compost Addition Enhanced Hyphal Growth and Sporulation of Arbuscular Mycorrhizal Fungi without Affecting Their Community Composition in the Soil.

Yang W, Gu S, Xin Y, Bello A, Sun W, Xu X.

Front Microbiol. 2018 Feb 7;9:169. doi: 10.3389/fmicb.2018.00169. eCollection 2018.


Cryobacterium aureum sp. nov., a psychrophilic bacterium isolated from glacier ice collected from the ice tongue surface.

Liu Q, Xin YH, Chen XL, Liu HC, Zhou YG, Chen WX.

Int J Syst Evol Microbiol. 2018 Apr;68(4):1173-1176. doi: 10.1099/ijsem.0.002647. Epub 2018 Feb 20.


Intramolecular Photocycloaddition of 2(5 H)-Furanones to Temporarily Tethered Terminal Alkenes as a Stereoselective Source of Enantiomerically Pure Polyfunctionalyzed Cyclobutanes.

Xin Y, Rodríguez-Santiago L, Sodupe M, Álvarez-Larena A, Busqué F, Alibés R.

J Org Chem. 2018 Mar 16;83(6):3188-3199. doi: 10.1021/acs.joc.8b00088. Epub 2018 Mar 1.


Final results of a phase 1b study of the safety and efficacy of the PI3Kδ inhibitor acalisib (GS-9820) in relapsed/refractory lymphoid malignancies.

Kater AP, Tonino SH, Spiering M, Chamuleau MED, Liu R, Adewoye AH, Gao J, Dreiling L, Xin Y, Doorduijn JK, Kersten MJ; HOVON Lunenburg Lymphoma Phase I/II Consortium.

Blood Cancer J. 2018 Feb 12;8(2):16. doi: 10.1038/s41408-018-0055-x. No abstract available.


Circular RNAs: a new frontier for cancer diagnosis and therapy.

Zhang M, Xin Y.

J Hematol Oncol. 2018 Feb 13;11(1):21. doi: 10.1186/s13045-018-0569-5. Review.


Coupling the recombineering to Cre-lox system enables simplified large-scale genome deletion in Lactobacillus casei.

Xin Y, Guo T, Mu Y, Kong J.

Microb Cell Fact. 2018 Feb 12;17(1):21. doi: 10.1186/s12934-018-0872-4.


Ru Nanoparticles-Loaded Covalent Organic Framework for Solvent-Free One-Pot Tandem Reactions in Air.

Chen GJ, Li XB, Zhao CC, Ma HC, Kan JL, Xin YB, Chen CX, Dong YB.

Inorg Chem. 2018 Mar 5;57(5):2678-2685. doi: 10.1021/acs.inorgchem.7b03077. Epub 2018 Feb 12.


Unstable Inflation Causing Injury: Insight from Prone Position and Paired CT Scans.

Xin Y, Cereda M, Hamedani H, Pourfathi M, Siddiqui S, Meeder N, Kadlecek S, Duncan I, Profka H, Rajaei J, Tustison NJ, Gee JC, Kavanagh BP, Rizi RR.

Am J Respir Crit Care Med. 2018 Feb 8. doi: 10.1164/rccm.201708-1728OC. [Epub ahead of print]


Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.

Zhang J, Yuan JP, Wang Q, Shao LH, Liu SP, Firestone RA, Hong YP, Li JG, Xin YC, Li Y.

Oncotarget. 2017 Dec 14;9(2):1957-1968. doi: 10.18632/oncotarget.23319. eCollection 2018 Jan 5.


The Drug-Drug Interaction Profile of Presatovir.

Xin Y, Weng W, Murray BP, Eisenberg EJ, Chien JW, Ling J, Silverman JA.

J Clin Pharmacol. 2018 Feb 7. doi: 10.1002/jcph.1073. [Epub ahead of print]


Acute effects of different dynamic exercises on hamstring strain risk factors.

Chen CH, Xin Y, Lee KW, Lin MJ, Lin JJ.

PLoS One. 2018 Feb 1;13(2):e0191801. doi: 10.1371/journal.pone.0191801. eCollection 2018.


Chlorinated Polyfluorinated Ether Sulfonates Exhibit Higher Activity toward Peroxisome Proliferator-Activated Receptors Signaling Pathways than Perfluorooctanesulfonate.

Li CH, Ren XM, Ruan T, Cao LY, Xin Y, Guo LH, Jiang G.

Environ Sci Technol. 2018 Mar 6;52(5):3232-3239. doi: 10.1021/acs.est.7b06327. Epub 2018 Feb 12.


Delta-like Ligand-4-Notch Signaling Inhibition Regulates Pancreatic Islet Function and Insulin Secretion.

Billiard F, Karaliota S, Wang B, Stellas D, Serafimidis I, Manousopoulou A, Koutmani Y, Ninou E, Golubov J, DaNave A, Tsakanikas P, Xin Y, Zhang W, Sleeman M, Yancopoulos GD, Murphy AJ, Garbis SD, Karalis K, Skokos D.

Cell Rep. 2018 Jan 23;22(4):895-904. doi: 10.1016/j.celrep.2017.12.076. Epub 2018 Jan 28.


Spectrum and origin of mutations in sporadic cases of haemophilia A in China.

Lu Y, Xin Y, Dai J, Wu X, You G, Ding Q, Wu W, Wang X.

Haemophilia. 2018 Mar;24(2):291-298. doi: 10.1111/hae.13402. Epub 2018 Jan 30.


Role of Quzhou Fructus Aurantii Extract in Preventing and Treating Acute Lung Injury and Inflammation.

Li L, Zhang S, Xin Y, Sun J, Xie F, Yang L, Chen Z, Chen H, Liu F, Xuan Y, You Z.

Sci Rep. 2018 Jan 26;8(1):1698. doi: 10.1038/s41598-018-20083-z.


In Vivo Elasticity Mapping of Posterior Ocular Layers Using Acoustic Radiation Force Optical Coherence Elastography.

Qu Y, He Y, Saidi A, Xin Y, Zhou Y, Zhu J, Ma T, Silverman RH, Minckler DS, Zhou Q, Chen Z.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):455-461. doi: 10.1167/iovs.17-22971.


Modulatory Effect of Fermented Papaya Extracts on Mammary Gland Hyperplasia Induced by Estrogen and Progestin in Female Rats.

You Z, Sun J, Xie F, Chen Z, Zhang S, Chen H, Liu F, Li L, Chen G, Song Y, Xuan Y, Zheng G, Xin Y.

Oxid Med Cell Longev. 2017;2017:8235069. doi: 10.1155/2017/8235069. Epub 2017 Nov 20.


Clinical characteristics associated with subcutaneous tophi formation in Chinese gout patients: a retrospective study.

Ma L, Sun R, Jia Z, Zou Y, Xin Y, Cheng X, Liu T, Cui L, Liu Z, Wu X, Li C.

Clin Rheumatol. 2018 Jan 22. doi: 10.1007/s10067-017-3969-y. [Epub ahead of print]


Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway.

Xin Y, Bai Y, Jiang X, Zhou S, Wang Y, Wintergerst KA, Cui T, Ji H, Tan Y, Cai L.

Redox Biol. 2018 May;15:405-417. doi: 10.1016/j.redox.2017.12.016. Epub 2018 Jan 2.


PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression.

Tang H, Liang Y, Anders RA, Taube JM, Qiu X, Mulgaonkar A, Liu X, Harrington SM, Guo J, Xin Y, Xiong Y, Nham K, Silvers W, Hao G, Sun X, Chen M, Hannan R, Qiao J, Dong H, Peng H, Fu YX.

J Clin Invest. 2018 Feb 1;128(2):580-588. doi: 10.1172/JCI96061. Epub 2018 Jan 16.


Highly Stable and Luminescent Perovskite-Polymer Composites from a Convenient and Universal Strategy.

Xin Y, Zhao H, Zhang J.

ACS Appl Mater Interfaces. 2018 Feb 7;10(5):4971-4980. doi: 10.1021/acsami.7b16442. Epub 2018 Jan 24.


Microinjection of Antisense Morpholinos, CRISPR/Cas9 RNP, and RNA/DNA into Zebrafish Embryos.

Xin Y, Duan C.

Methods Mol Biol. 2018;1742:205-211. doi: 10.1007/978-1-4939-7665-2_18.


Biointeractions of Herbicide Atrazine with Human Serum Albumin: UV-Vis, Fluorescence and Circular Dichroism Approaches.

Zhu M, Wang L, Wang Y, Zhou J, Ding J, Li W, Xin Y, Fan S, Wang Z, Wang Y.

Int J Environ Res Public Health. 2018 Jan 11;15(1). pii: E116. doi: 10.3390/ijerph15010116.


Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation.

Sieber JD, Rodriguez S, Frutos R, Buono F, Zhang Y, Li N, Qu B, Premasiri A, Li Z, Han ZS, Xu Y, Byrne D, Haddad N, Lorenz J, Grinberg N, Kurouski D, Lee H, Narayanan B, Nummy L, Mulder J, Brown JD, Granger A, Gao J, Krawiec M, Williams Z, Pennino S, Song JJ, Hossain A, Yee NK, Busacca C, Roschangar F, Xin Y, Mao Z, Zhang X, Hong Y, Senanayake CH.

J Org Chem. 2018 Feb 2;83(3):1448-1461. doi: 10.1021/acs.joc.7b03022. Epub 2018 Jan 23.


Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development.

Zheng J, Xin Y, Zhang J, Subramanian R, Murray BP, Whitney JA, Warr MR, Ling J, Moorehead L, Kwan E, Hemenway J, Smith BJ, Silverman JA.

Drug Metab Dispos. 2018 Mar;46(3):237-247. doi: 10.1124/dmd.117.078899. Epub 2018 Jan 8.


A Cytoplasmic Antiholin Is Embedded In Frame with the Holin in a Lactobacillus fermentum Bacteriophage.

Guo T, Xin Y, Zhang C, Kong J.

Appl Environ Microbiol. 2018 Mar 1;84(6). pii: e02518-17. doi: 10.1128/AEM.02518-17. Print 2018 Mar 15.


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