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Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.

Goodwin E, Gilman MSA, Wrapp D, Chen M, Ngwuta JO, Moin SM, Bai P, Sivasubramanian A, Connor RI, Wright PF, Graham BS, McLellan JS, Walker LM.

Immunity. 2018 Feb 20;48(2):339-349.e5. doi: 10.1016/j.immuni.2018.01.005. Epub 2018 Feb 3.


Preliminary investigation of human exhaled breath for tuberculosis diagnosis by multidimensional gas chromatography - Time of flight mass spectrometry and machine learning.

Beccaria M, Mellors TR, Petion JS, Rees CA, Nasir M, Systrom HK, Sairistil JW, Jean-Juste MA, Rivera V, Lavoile K, Severe P, Pape JW, Wright PF, Hill JE.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Feb 1;1074-1075:46-50. doi: 10.1016/j.jchromb.2018.01.004. Epub 2018 Jan 4.


Mucosal Immunity: The Forgotten Arm of the Immune System: Synopsis of the Pediatric Infectious Disease Society's 2017 Stanley A. Plotkin Lecture in Vaccinology.

Wright PF, Ackerman ME, Brickley EB.

J Pediatric Infect Dis Soc. 2017 Dec 22. doi: 10.1093/jpids/pix102. [Epub ahead of print]


Intestinal Immune Responses to Type 2 Oral Polio Vaccine (OPV) Challenge in Infants Previously Immunized With Bivalent OPV and Either High-Dose or Standard Inactivated Polio Vaccine.

Brickley EB, Strauch CB, Wieland-Alter WF, Connor RI, Lin S, Weiner JA, Ackerman ME, Arita M, Oberste MS, Weldon WC, Sáez-Llorens X, Bandyopadhyay AS, Wright PF.

J Infect Dis. 2018 Jan 17;217(3):371-380. doi: 10.1093/infdis/jix556.


Volatile fingerprinting of human respiratory viruses from cell culture.

Purcaro G, Rees CA, Wieland-Alter WF, Schneider MJ, Wang X, Stefanuto PH, Wright PF, Enelow RI, Hill JE.

J Breath Res. 2018 Mar 1;12(2):026015. doi: 10.1088/1752-7163/aa9eef.


Maximising the impact of inactivated polio vaccines.

Brickley EB, Wright PF.

Lancet Infect Dis. 2017 Jul;17(7):680-681. doi: 10.1016/S1473-3099(17)30236-0. Epub 2017 Apr 25. No abstract available.


Porous 45S5 Bioglass®-based scaffolds using stereolithography: Effect of partial pre-sintering on structural and mechanical properties of scaffolds.

Thavornyutikarn B, Tesavibul P, Sitthiseripratip K, Chatarapanich N, Feltis B, Wright PFA, Turney TW.

Mater Sci Eng C Mater Biol Appl. 2017 Jun 1;75:1281-1288. doi: 10.1016/j.msec.2017.03.001. Epub 2017 Mar 2.


Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors.

Gilman MS, Castellanos CA, Chen M, Ngwuta JO, Goodwin E, Moin SM, Mas V, Melero JA, Wright PF, Graham BS, McLellan JS, Walker LM.

Sci Immunol. 2016 Dec 16;1(6). pii: eaaj1879. doi: 10.1126/sciimmunol.aaj1879. Epub 2016 Dec 9.


Retention in Care among HIV-Infected Pregnant Women in Haiti with PMTCT Option B.

Dionne-Odom J, Massaro C, Jogerst KM, Li Z, Deschamps MM, Destine CJ, Senecharles R, Aristhene MM, Domercant JY, Rouzier V, Wright PF.

AIDS Res Treat. 2016;2016:6284290. doi: 10.1155/2016/6284290. Epub 2016 Aug 29.


Vaccine-induced mucosal immunity to poliovirus: analysis of cohorts from an open-label, randomised controlled trial in Latin American infants.

Wright PF, Connor RI, Wieland-Alter WF, Hoen AG, Boesch AW, Ackerman ME, Oberste MS, Gast C, Brickley EB, Asturias EJ, Rüttimann R, Bandyopadhyay AS.

Lancet Infect Dis. 2016 Dec;16(12):1377-1384. doi: 10.1016/S1473-3099(16)30169-4. Epub 2016 Sep 13.


In Response.

Sévère K, Rouzier V, Anglade SB, Bertil C, Joseph P, Deroncelay A, Mabou MM, Wright PF, Guillaume FD, Pape JW.

Am J Trop Med Hyg. 2016 Aug 3;95(2):495-6. doi: 10.4269/ajtmh.16-0314b. No abstract available.


Correlates of Immunity to Influenza as Determined by Challenge of Children with Live, Attenuated Influenza Vaccine.

Wright PF, Hoen AG, Ilyushina NA, Brown EP, Ackerman ME, Wieland-Alter W, Connor RI, Jegaskanda S, Rosenberg-Hasson Y, Haynes BC, Luke CJ, Subbarao K, Treanor JJ.

Open Forum Infect Dis. 2016 May 23;3(2):ofw108. doi: 10.1093/ofid/ofw108. eCollection 2016 Apr.


Generation and Protective Ability of Influenza Virus-Specific Antibody-Dependent Cellular Cytotoxicity in Humans Elicited by Vaccination, Natural Infection, and Experimental Challenge.

Jegaskanda S, Luke C, Hickman HD, Sangster MY, Wieland-Alter WF, McBride JM, Yewdell JW, Wright PF, Treanor J, Rosenberger CM, Subbarao K.

J Infect Dis. 2016 Sep 15;214(6):945-52. doi: 10.1093/infdis/jiw262. Epub 2016 Jun 28.


ZnO nanoparticles and organic chemical UV-filters are equally well tolerated by human immune cells.

O'Keefe SJ, Feltis BN, Piva TJ, Turney TW, Wright PF.

Nanotoxicology. 2016 Nov;10(9):1287-96. doi: 10.1080/17435390.2016.1206148. Epub 2016 Jul 19.


Potential risks and benefits of nanotechnology: perceptions of risk in sunscreens.

Wright PF.

Med J Aust. 2016 Jun 6;204(10):369-70. No abstract available.


Elucidation of the hepatoprotective moiety of 5β-scymnol that suppresses paracetamol toxicity in mice.

Hodges LD, Carter F, Kalafatis N, Wright PF, Macrides TA.

Mol Cell Biochem. 2016 Jun;417(1-2):135-40. doi: 10.1007/s11010-016-2720-3. Epub 2016 May 27.


In vitro modeling of the interaction between human epithelial cells and lymphocytes upon influenza infection.

Ilyushina NA, Wright PF.

Influenza Other Respir Viruses. 2016 Sep;10(5):438-42. doi: 10.1111/irv.12394. Epub 2016 May 17.


Effectiveness of Oral Cholera Vaccine in Haiti: 37-Month Follow-Up.

Sévère K, Rouzier V, Anglade SB, Bertil C, Joseph P, Deroncelay A, Mabou MM, Wright PF, Guillaume FD, Pape JW.

Am J Trop Med Hyg. 2016 May 4;94(5):1136-42. doi: 10.4269/ajtmh.15-0700. Epub 2016 Feb 29.


Shedding of TNF receptor 2 by effector CD8⁺ T cells by ADAM17 is important for regulating TNF-α availability during influenza infection.

DeBerge MP, Ely KH, Wright PF, Thorp EB, Enelow RI.

J Leukoc Biol. 2015 Sep;98(3):423-34. doi: 10.1189/jlb.3A0914-432RR. Epub 2015 May 27.


Characterizing the inhibitory action of zinc oxide nanoparticles on allergic-type mast cell activation.

Feltis BN, Elbaz A, Wright PF, Mackay GA, Turney TW, Lopata AL.

Mol Immunol. 2015 Aug;66(2):139-46. doi: 10.1016/j.molimm.2015.02.021. Epub 2015 Mar 12.


Investigating the immunomodulatory nature of zinc oxide nanoparticles at sub-cytotoxic levels in vitro and after intranasal instillation in vivo.

Saptarshi SR, Feltis BN, Wright PF, Lopata AL.

J Nanobiotechnology. 2015 Feb 3;13:6. doi: 10.1186/s12951-015-0067-7.


Adapting and Implementing a Community Program to Improve Retention in Care among Patients with HIV in Southern Haiti: "Group of 6".

Naslund JA, Dionne-Odom J, Junior Destiné C, Jogerst KM, Renold Sénécharles R, Jean Louis M, Desir J, Néptune Ledan Y, Beauséjour JR, Charles R, Werbel A, Talbot EA, Joseph P, Pape JW, Wright PF.

AIDS Res Treat. 2014;2014:137545. doi: 10.1155/2014/137545. Epub 2014 Dec 7.


Live attenuated and inactivated influenza vaccines in children.

Ilyushina NA, Haynes BC, Hoen AG, Khalenkov AM, Housman ML, Brown EP, Ackerman ME, Treanor JJ, Luke CJ, Subbarao K, Wright PF.

J Infect Dis. 2015 Feb 1;211(3):352-60. doi: 10.1093/infdis/jiu458. Epub 2014 Aug 26.


Progress in the prevention and treatment of RSV infection.

Wright PF.

N Engl J Med. 2014 Aug 21;371(8):776-7. doi: 10.1056/NEJMe1407467. No abstract available.


Reducing ZnO nanoparticle cytotoxicity by surface modification.

Luo M, Shen C, Feltis BN, Martin LL, Hughes AE, Wright PF, Turney TW.

Nanoscale. 2014 Jun 7;6(11):5791-8. doi: 10.1039/c4nr00458b. Epub 2014 Apr 17.


Comparison of UVA-induced ROS and sunscreen nanoparticle-generated ROS in human immune cells.

Shen C, Turney TW, Piva TJ, Feltis BN, Wright PF.

Photochem Photobiol Sci. 2014 May;13(5):781-8. doi: 10.1039/c3pp50428j.


Intestinal immunity is a determinant of clearance of poliovirus after oral vaccination.

Wright PF, Wieland-Alter W, Ilyushina NA, Hoen AG, Arita M, Boesch AW, Ackerman ME, van der Avoort H, Oberste MS, Pallansch MA, Burton AH, Jaffar MA, Sutter RW.

J Infect Dis. 2014 May 15;209(10):1628-34. doi: 10.1093/infdis/jit671. Epub 2014 Jan 23.


Importance of cholera and other etiologies of acute diarrhea in post-earthquake Port-au-Prince, Haiti.

Charles M, Delva GG, Boutin J, Severe K, Peck M, Mabou MM, Wright PF, Pape JW.

Am J Trop Med Hyg. 2014 Mar;90(3):511-7. doi: 10.4269/ajtmh.13-0514. Epub 2014 Jan 20.


Quantification of ZnO nanoparticle uptake, distribution, and dissolution within individual human macrophages.

James SA, Feltis BN, de Jonge MD, Sridhar M, Kimpton JA, Altissimo M, Mayo S, Zheng C, Hastings A, Howard DL, Paterson DJ, Wright PF, Moorhead GF, Turney TW, Fu J.

ACS Nano. 2013 Dec 23;7(12):10621-35. doi: 10.1021/nn403118u. Epub 2013 Nov 11.


Cholera vaccination in urban Haiti.

Rouzier V, Severe K, Juste MA, Peck M, Perodin C, Severe P, Deschamps MM, Verdier RI, Prince S, Francois J, Cadet JR, Guillaume FD, Wright PF, Pape JW.

Am J Trop Med Hyg. 2013 Oct;89(4):671-81. doi: 10.4269/ajtmh.13-0171.


Predictors of disease severity in patients admitted to a cholera treatment center in urban Haiti.

Valcin CL, Severe K, Riche CT, Anglade BS, Moise CG, Woodworth M, Charles M, Li Z, Joseph P, Pape JW, Wright PF.

Am J Trop Med Hyg. 2013 Oct;89(4):625-32. doi: 10.4269/ajtmh.13-0170. Erratum in: Am J Trop Med Hyg. 2013 Nov;89(5):1035.


Relating cytotoxicity, zinc ions, and reactive oxygen in ZnO nanoparticle-exposed human immune cells.

Shen C, James SA, de Jonge MD, Turney TW, Wright PF, Feltis BN.

Toxicol Sci. 2013 Nov;136(1):120-30. doi: 10.1093/toxsci/kft187. Epub 2013 Aug 31.


The live attenuated chimeric vaccine rWN/DEN4Δ30 is well-tolerated and immunogenic in healthy flavivirus-naïve adult volunteers.

Durbin AP, Wright PF, Cox A, Kagucia W, Elwood D, Henderson S, Wanionek K, Speicher J, Whitehead SS, Pletnev AG.

Vaccine. 2013 Nov 19;31(48):5772-7. doi: 10.1016/j.vaccine.2013.07.064. Epub 2013 Aug 19.


B cell response and hemagglutinin stalk-reactive antibody production in different age cohorts following 2009 H1N1 influenza virus vaccination.

Sangster MY, Baer J, Santiago FW, Fitzgerald T, Ilyushina NA, Sundararajan A, Henn AD, Krammer F, Yang H, Luke CJ, Zand MS, Wright PF, Treanor JJ, Topham DJ, Subbarao K.

Clin Vaccine Immunol. 2013 Jun;20(6):867-76. doi: 10.1128/CVI.00735-12. Epub 2013 Apr 10.


Review and assessment of poliovirus immunity and transmission: synthesis of knowledge gaps and identification of research needs.

Duintjer Tebbens RJ, Pallansch MA, Chumakov KM, Halsey NA, Hovi T, Minor PD, Modlin JF, Patriarca PA, Sutter RW, Wright PF, Wassilak SG, Cochi SL, Kim JH, Thompson KM.

Risk Anal. 2013 Apr;33(4):606-46. doi: 10.1111/risa.12031. Epub 2013 Mar 28. Review.


Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: a randomised, double-blind, placebo-controlled, phase 1 study.

Gurwith M, Lock M, Taylor EM, Ishioka G, Alexander J, Mayall T, Ervin JE, Greenberg RN, Strout C, Treanor JJ, Webby R, Wright PF.

Lancet Infect Dis. 2013 Mar;13(3):238-50. doi: 10.1016/S1473-3099(12)70345-6. Epub 2013 Jan 29.


Human rhinovirus C: Age, season, and lower respiratory illness over the past 3 decades.

Linder JE, Kraft DC, Mohamed Y, Lu Z, Heil L, Tollefson S, Saville BR, Wright PF, Williams JV, Miller EK.

J Allergy Clin Immunol. 2013 Jan;131(1):69-77.e1-6. doi: 10.1016/j.jaci.2012.09.033. Epub 2012 Nov 10.


Circulating vaccine derived poliovirus and the polio eradication endgame.

Davis R, Wright PF.

Pan Afr Med J. 2012;12:109. Epub 2012 Aug 20. No abstract available.


Formation of zinc-containing nanoparticles from Zn²⁺ ions in cell culture media: implications for the nanotoxicology of ZnO.

Turney TW, Duriska MB, Jayaratne V, Elbaz A, O'Keefe SJ, Hastings AS, Piva TJ, Wright PF, Feltis BN.

Chem Res Toxicol. 2012 Oct 15;25(10):2057-66. doi: 10.1021/tx300241q. Epub 2012 Sep 27.


Comparative study of influenza virus replication in MDCK cells and in primary cells derived from adenoids and airway epithelium.

Ilyushina NA, Ikizler MR, Kawaoka Y, Rudenko LG, Treanor JJ, Subbarao K, Wright PF.

J Virol. 2012 Nov;86(21):11725-34. doi: 10.1128/JVI.01477-12. Epub 2012 Aug 22.


Seasonal maintenance of influenza vaccine-induced antibody response in kidney transplant recipients.

Birdwell KA, Ikizler MR, Wang L, Byrne DW, Sannella EC, Wright PF, Ikizler TA.

Am J Nephrol. 2012;36(3):201-7. Epub 2012 Aug 17.


Consideration of postpartum management in HIV-positive Haitian women: an analysis of CD4 decline, mortality, and follow-up after delivery.

Coria A, Noel F, Bonhomme J, Rouzier V, Perodin C, Marcelin A, Li Z, Tosteson TD, Deschamps MM, Wright PF, Pape JW.

J Acquir Immune Defic Syndr. 2012 Dec 15;61(5):636-43. doi: 10.1097/QAI.0b013e31826abdd1.


Expert review on poliovirus immunity and transmission.

Duintjer Tebbens RJ, Pallansch MA, Chumakov KM, Halsey NA, Hovi T, Minor PD, Modlin JF, Patriarca PA, Sutter RW, Wright PF, Wassilak SG, Cochi SL, Kim JH, Thompson KM.

Risk Anal. 2013 Apr;33(4):544-605. doi: 10.1111/j.1539-6924.2012.01864.x. Epub 2012 Jul 15. Review.


Selective impact of HIV disease progression on the innate immune system in the human female reproductive tract.

Lahey T, Ghosh M, Fahey JV, Shen Z, Mukura LR, Song Y, Cu-Uvin S, Mayer KH, Wright PF, Kappes JC, Ochsenbauer C, Wira CR.

PLoS One. 2012;7(6):e38100. doi: 10.1371/journal.pone.0038100. Epub 2012 Jun 4.


Independent cytotoxic and inflammatory responses to zinc oxide nanoparticles in human monocytes and macrophages.

Feltis BN, OKeefe SJ, Harford AJ, Piva TJ, Turney TW, Wright PF.

Nanotoxicology. 2012 Nov;6(7):757-65. doi: 10.3109/17435390.2011.620718. Epub 2011 Nov 17.


Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis.

Nair H, Brooks WA, Katz M, Roca A, Berkley JA, Madhi SA, Simmerman JM, Gordon A, Sato M, Howie S, Krishnan A, Ope M, Lindblade KA, Carosone-Link P, Lucero M, Ochieng W, Kamimoto L, Dueger E, Bhat N, Vong S, Theodoratou E, Chittaganpitch M, Chimah O, Balmaseda A, Buchy P, Harris E, Evans V, Katayose M, Gaur B, O'Callaghan-Gordo C, Goswami D, Arvelo W, Venter M, Briese T, Tokarz R, Widdowson MA, Mounts AW, Breiman RF, Feikin DR, Klugman KP, Olsen SJ, Gessner BD, Wright PF, Rudan I, Broor S, Simões EA, Campbell H.

Lancet. 2011 Dec 3;378(9807):1917-30. doi: 10.1016/S0140-6736(11)61051-9. Epub 2011 Nov 10. Review.


Aprotinin and similar protease inhibitors as drugs against influenza.

Zhirnov OP, Klenk HD, Wright PF.

Antiviral Res. 2011 Oct;92(1):27-36. doi: 10.1016/j.antiviral.2011.07.014. Epub 2011 Jul 23. Review.


A fatal central nervous system enterovirus 68 infection.

Kreuter JD, Barnes A, McCarthy JE, Schwartzman JD, Oberste MS, Rhodes CH, Modlin JF, Wright PF.

Arch Pathol Lab Med. 2011 Jun;135(6):793-6. doi: 10.1043/2010-0174-CR.1.


An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children.

Nair H, Verma VR, Theodoratou E, Zgaga L, Huda T, Simões EA, Wright PF, Rudan I, Campbell H.

BMC Public Health. 2011 Apr 13;11 Suppl 3:S30. doi: 10.1186/1471-2458-11-S3-S30. Review.


Serologic imprint of dengue virus in urban Haiti: characterization of humoral immunity to dengue in infants and young children.

Rioth M, Beauharnais CA, Noel F, Ikizler MR, Mehta S, Zhu Y, Long CA, Pape JW, Wright PF.

Am J Trop Med Hyg. 2011 Apr;84(4):630-6. doi: 10.4269/ajtmh.2011.10-0323.

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