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A Paediatric Acute Promyelocytic Leukaemia Patient Harbouring a Cryptic PML-RARA Insertion due to a Complex Structural Chromosome 17 Rearrangement.

El-Hajj Ghaoui R, St Heaps L, Hung D, Nagabushan S, Harris C, Mirochnik O, Sharma P, Kellie SJ, Wright DC.

Cytogenet Genome Res. 2018 Mar 17;153(4). doi: 10.1159/000487000. [Epub ahead of print]


Exercise Protects Against Olanzapine-Induced Hyperglycemia in Male C57BL/6J Mice.

Castellani LN, Peppler WT, Miotto PM, Bush N, Wright DC.

Sci Rep. 2018 Jan 15;8(1):772. doi: 10.1038/s41598-018-19260-x.


Obesity exacerbates the acute metabolic side effects of olanzapine.

Townsend LK, Peppler WT, Bush ND, Wright DC.

Psychoneuroendocrinology. 2018 Feb;88:121-128. doi: 10.1016/j.psyneuen.2017.12.004. Epub 2017 Dec 8.


Rosiglitazone is superior to resveratrol in inducing the expression of glyceroneogenic genes in adipose tissue from obese participants.

Beaudoin MS, Gaudio N, Reed JK, Foute-Nelong J, Mutch DM, Wright DC.

Appl Physiol Nutr Metab. 2018 Mar;43(3):307-311. doi: 10.1139/apnm-2017-0606. Epub 2017 Nov 16.


Subcutaneous inguinal white adipose tissue is responsive to, but dispensable for, the metabolic health benefits of exercise.

Peppler WT, Townsend LK, Knuth CM, Foster MT, Wright DC.

Am J Physiol Endocrinol Metab. 2018 Jan 1;314(1):E66-E77. doi: 10.1152/ajpendo.00226.2017. Epub 2017 Oct 3.


Proliferative endocrine effects of adipose tissue from obese animals on MCF7 cells are ameliorated by resveratrol supplementation.

Theriau CF, Sauvé OS, Beaudoin MS, Wright DC, Connor MK.

PLoS One. 2017 Sep 5;12(9):e0183897. doi: 10.1371/journal.pone.0183897. eCollection 2017.


Dairy Attenuates Weight Gain to a Similar Extent as Exercise in Rats Fed a High-Fat, High-Sugar Diet.

Trottier SK, MacPherson REK, Knuth CM, Townsend LK, Peppler WT, Mikhaeil JS, Leveille CF, LeBlanc PJ, Shearer J, Reimer RA, Wright DC.

Obesity (Silver Spring). 2017 Oct;25(10):1707-1715. doi: 10.1002/oby.21941. Epub 2017 Aug 7.


Reduced SCD1 activity alters markers of fatty acid reesterification, glyceroneogenesis, and lipolysis in murine white adipose tissue and 3T3-L1 adipocytes.

Dragos SM, Bergeron KF, Desmarais F, Suitor K, Wright DC, Mounier C, Mutch DM.

Am J Physiol Cell Physiol. 2017 Sep 1;313(3):C295-C304. doi: 10.1152/ajpcell.00097.2017. Epub 2017 Jun 28.


Microbiome and NAFLD: potential influence of aerobic fitness and lifestyle modification.

Panasevich MR, Peppler WT, Oerther DB, Wright DC, Rector RS.

Physiol Genomics. 2017 Aug 1;49(8):385-399. doi: 10.1152/physiolgenomics.00012.2017. Epub 2017 Jun 9. Review.


Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive.

Foster AJ, Platt MJ, Huber JS, Eadie AL, Arkell AM, Romanova N, Wright DC, Gillis TE, Murrant CL, Brunt KR, Simpson JA.

Sci Transl Med. 2017 May 17;9(390). pii: eaag1303. doi: 10.1126/scitranslmed.aag1303.


Glucagon receptor knockout mice are protected against acute olanzapine-induced hyperglycemia.

Castellani LN, Peppler WT, Sutton CD, Whitfield J, Charron MJ, Wright DC.

Psychoneuroendocrinology. 2017 Aug;82:38-45. doi: 10.1016/j.psyneuen.2017.05.005. Epub 2017 May 3.


Habitual physical activity protects against lipopolysaccharide-induced inflammation in mouse adipose tissue.

Peppler WT, Anderson ZG, MacRae LM, MacPherson REK, Wright DC.

Adipocyte. 2017 Jan 2;6(1):1-11. doi: 10.1080/21623945.2016.1259778. Epub 2016 Nov 14.


Estradiol does not directly regulate adipose lipolysis.

MacDonald TL, MacPherson R, Castellani L, Cervone D, Anderson E, Wright DC, Dyck DJ.

Adipocyte. 2017 Apr 3;6(2):76-86. doi: 10.1080/21623945.2017.1287638. Epub 2017 Jan 27.


Cycling our way to fit fat.

Townsend LK, Knuth CM, Wright DC.

Physiol Rep. 2017 Apr;5(7). pii: e13247. doi: 10.14814/phy2.13247. Review.


Who is and isn't having babies with Down syndrome in western Sydney: a ten year hospital cohort study.

Moses RM, Brown JH, Wright DC, Diplock H, Melov SJ, McGee TM.

Aust N Z J Obstet Gynaecol. 2017 Apr;57(2):146-151. doi: 10.1111/ajo.12617. Epub 2017 Mar 29.


CL 316, 243 mediated reductions in blood glucose are enhanced in RIP140-/- mice independent of alterations in lipolysis.

Peppler WT, Miotto PM, Holloway GP, Wright DC.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):486-491. doi: 10.1016/j.bbrc.2017.03.067. Epub 2017 Mar 18.


Dietary α-linolenic acid supplementation alters skeletal muscle plasma membrane lipid composition, sarcolemmal FAT/CD36 abundance, and palmitate transport rates.

Chorner Z, Barbeau PA, Castellani L, Wright DC, Chabowski A, Holloway GP.

Am J Physiol Regul Integr Comp Physiol. 2016 Dec 1;311(6):R1234-R1242. doi: 10.1152/ajpregu.00346.2016. Epub 2016 Nov 2.


Chromosome microarray proficiency testing and analysis of quality metric data trends through an external quality assessment program for Australasian laboratories.

Wright DC, Adayapalam N, Bain N, Bain SM, Brown A, Buzzacott N, Carey L, Cross J, Dun K, Joy C, McCarthy C, Moore S, Murch AR, O'Malley F, Parker E, Watt J, Wilkin H, Fagan K, Pertile MD, Peters GB.

Pathology. 2016 Oct;48(6):586-96. doi: 10.1016/j.pathol.2016.05.009. Epub 2016 Aug 26.


"Weighing" the effects of exercise and intrinsic aerobic capacity: are there beneficial effects independent of changes in weight?

Thyfault JP, Wright DC.

Appl Physiol Nutr Metab. 2016 Sep;41(9):911-6. doi: 10.1139/apnm-2016-0122. Epub 2016 May 6. Review.


Statin Therapy Alters Lipid Storage in Diabetic Skeletal Muscle.

Rebalka IA, Raleigh MJ, Snook LA, Rebalka AN, MacPherson RE, Wright DC, Schertzer JD, Hawke TJ.

Front Endocrinol (Lausanne). 2016 Jul 19;7:95. doi: 10.3389/fendo.2016.00095. eCollection 2016.


Beneficial effects of combined resveratrol and metformin therapy in treating diet-induced insulin resistance.

Frendo-Cumbo S, MacPherson RE, Wright DC.

Physiol Rep. 2016 Aug;4(15). pii: e12877. doi: 10.14814/phy2.12877.


Challenging dogma: is hepatic lipid accumulation in type 2 diabetes due to mitochondrial dysfunction?

Perry CG, Wright DC.

J Physiol. 2016 Aug 1;594(15):4093-4. doi: 10.1113/JP272573. No abstract available.


Reduced ATGL-mediated lipolysis attenuates β-adrenergic-induced AMPK signaling, but not the induction of PKA-targeted genes, in adipocytes and adipose tissue.

MacPherson RE, Dragos SM, Ramos S, Sutton C, Frendo-Cumbo S, Castellani L, Watt MJ, Perry CG, Mutch DM, Wright DC.

Am J Physiol Cell Physiol. 2016 Aug 1;311(2):C269-76. doi: 10.1152/ajpcell.00126.2016. Epub 2016 Jun 29.


Sarcolipin knockout mice fed a high-fat diet exhibit altered indices of adipose tissue inflammation and remodeling.

MacPherson RE, Gamu D, Frendo-Cumbo S, Castellani L, Kwon F, Tupling AR, Wright DC.

Obesity (Silver Spring). 2016 Jul;24(7):1499-505. doi: 10.1002/oby.21521.


Postprandial control of fatty acid transport proteins' subcellular location is not dependent on insulin.

Snook LA, Wright DC, Holloway GP.

FEBS Lett. 2016 Aug;590(16):2661-70. doi: 10.1002/1873-3468.12260. Epub 2016 Jul 4.


North American ginseng influences adipocyte-macrophage crosstalk regulation of inflammatory gene expression.

Garbett J, Wilson SA, Ralston JC, De Boer AA, Lui EM, Wright DC, Mutch DM.

J Ginseng Res. 2016 Apr;40(2):141-50. doi: 10.1016/j.jgr.2015.07.001. Epub 2015 Jul 18.


Prior exercise training blunts short-term high-fat diet-induced weight gain.

Snook LA, MacPherson RE, Monaco CM, Frendo-Cumbo S, Castellani L, Peppler WT, Anderson ZG, Buzelle SL, LeBlanc PJ, Holloway GP, Wright DC.

Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R315-24. doi: 10.1152/ajpregu.00072.2016. Epub 2016 Apr 13.


Combined high-fat-resveratrol diet and RIP140 knockout mice reveal a novel relationship between elevated bone mitochondrial content and compromised bone microarchitecture, bone mineral mass, and bone strength in the tibia.

Miotto PM, Frendo-Cumbo S, Sacco SM, Wright DC, Ward WE, Holloway GP.

Mol Nutr Food Res. 2016 Sep;60(9):1994-2007. doi: 10.1002/mnfr.201500870. Epub 2016 Apr 21.


Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of Infancy: Overlapping Genetic Features With Clear Cell Sarcoma of Kidney.

Kao YC, Sung YS, Zhang L, Huang SC, Argani P, Chung CT, Graf NS, Wright DC, Kellie SJ, Agaram NP, Ludwig K, Zin A, Alaggio R, Antonescu CR.

Am J Surg Pathol. 2016 Aug;40(8):1009-20. doi: 10.1097/PAS.0000000000000629.


Voluntary wheel running attenuates lipopolysaccharide-induced liver inflammation in mice.

Peppler WT, Anderson ZG, Sutton CD, Rector RS, Wright DC.

Am J Physiol Regul Integr Comp Physiol. 2016 May 15;310(10):R934-42. doi: 10.1152/ajpregu.00497.2015. Epub 2016 Feb 17.


Molecular genetic studies of complete hydatidiform moles.

Carey L, Nash BM, Wright DC.

Transl Pediatr. 2015 Apr;4(2):181-8. doi: 10.3978/j.issn.2224-4336.2015.04.02. Review.


Retinal dystrophies, genomic applications in diagnosis and prospects for therapy.

Nash BM, Wright DC, Grigg JR, Bennetts B, Jamieson RV.

Transl Pediatr. 2015 Apr;4(2):139-63. doi: 10.3978/j.issn.2224-4336.2015.04.03. Review.


Exercise-mediated IL-6 signaling occurs independent of inflammation and is amplified by training in mouse adipose tissue.

Castellani L, Perry CG, Macpherson RE, Root-McCaig J, Huber JS, Arkell AM, Simpson JA, Wright DC.

J Appl Physiol (1985). 2015 Dec 1;119(11):1347-54. doi: 10.1152/japplphysiol.00551.2015. Epub 2015 Oct 15.


JRK is a positive regulator of β-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer.

Pangon L, Ng I, Giry-Laterriere M, Currey N, Morgan A, Benthani F, Tran PN, Al-Sohaily S, Segelov E, Parker BL, Cowley MJ, Wright DC, St Heaps L, Carey L, Rooman I, Kohonen-Corish MR.

Oncogene. 2016 Jun 2;35(22):2834-41. doi: 10.1038/onc.2015.347. Epub 2015 Oct 12.


Feeding butter with elevated content of trans-10, cis-12 conjugated linoleic acid to obese-prone rats impairs glucose and insulin tolerance.

Hamilton M, Hopkins LE, AlZahal O, MacDonald TL, Cervone DT, Wright DC, McBride BW, Dyck DJ.

Lipids Health Dis. 2015 Sep 28;14:119. doi: 10.1186/s12944-015-0122-2.


Reduced cortical BACE1 content with one bout of exercise is accompanied by declines in AMPK, Akt, and MAPK signaling in obese, glucose-intolerant mice.

MacPherson RE, Baumeister P, Peppler WT, Wright DC, Little JP.

J Appl Physiol (1985). 2015 Nov 15;119(10):1097-104. doi: 10.1152/japplphysiol.00299.2015. Epub 2015 Sep 24.


Adipose tissue mitochondrial respiration: Key insights from RYGB-induced weight loss.

MacPherson RE, Wright DC.

Obesity (Silver Spring). 2015 Oct;23(10):1941. doi: 10.1002/oby.21234. Epub 2015 Sep 10. No abstract available.


Respiratory muscle weakness in the Zucker diabetic fatty rat.

Allwood MA, Foster AJ, Arkell AM, Beaudoin MS, Snook LA, Romanova N, Murrant CL, Holloway GP, Wright DC, Simpson JA.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct;309(7):R780-7. doi: 10.1152/ajpregu.00447.2014. Epub 2015 Aug 5.


Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats.

Bonen A, Jain SS, Snook LA, Han XX, Yoshida Y, Buddo KH, Lally JS, Pask ED, Paglialunga S, Beaudoin MS, Glatz JF, Luiken JJ, Harasim E, Wright DC, Chabowski A, Holloway GP.

Diabetologia. 2015 Oct;58(10):2381-91. doi: 10.1007/s00125-015-3691-8. Epub 2015 Jul 22.


Glucose-dependent insulinotropic polypeptide directly induces glucose transport in rat skeletal muscle.

Snook LA, Nelson EM, Dyck DJ, Wright DC, Holloway GP.

Am J Physiol Regul Integr Comp Physiol. 2015 Aug 1;309(3):R295-303. doi: 10.1152/ajpregu.00003.2015. Epub 2015 Jun 3.


Hyperactive mTORC1 signaling is unaffected by metformin treatment in aged skeletal muscle.

Dungan CM, Li Z, Wright DC, Williamson DL.

Muscle Nerve. 2016 Jan;53(1):107-17. doi: 10.1002/mus.24698. Epub 2015 Nov 23.


Adipose Tissue Insulin Action and IL-6 Signaling after Exercise in Obese Mice.

Macpherson RE, Huber JS, Frendo-Cumbo S, Simpson JA, Wright DC.

Med Sci Sports Exerc. 2015 Oct;47(10):2034-42. doi: 10.1249/MSS.0000000000000660.


The contribution of IL-6 to beta 3 adrenergic receptor mediated adipose tissue remodeling.

Buzelle SL, MacPherson RE, Peppler WT, Castellani L, Wright DC.

Physiol Rep. 2015 Feb 22;3(2). pii: e12312. doi: 10.14814/phy2.12312. Print 2015 Feb 1.


Heat shock proteins: in vivo heat treatments reveal adipose tissue depot-specific effects.

Rogers RS, Beaudoin MS, Wheatley JL, Wright DC, Geiger PC.

J Appl Physiol (1985). 2015 Jan 1;118(1):98-106. doi: 10.1152/japplphysiol.00286.2014. Epub 2014 Nov 13.


Lack of REDD1 reduces whole body glucose and insulin tolerance, and impairs skeletal muscle insulin signaling.

Dungan CM, Wright DC, Williamson DL.

Biochem Biophys Res Commun. 2014 Oct 31;453(4):778-83. doi: 10.1016/j.bbrc.2014.10.032. Epub 2014 Oct 14.


Adiponectin is not required for exercise training-induced improvements in glucose and insulin tolerance in mice.

Ritchie IR, Wright DC, Dyck DJ.

Physiol Rep. 2014 Sep 11;2(9). pii: e12146. doi: 10.14814/phy2.12146. Print 2014 Sep 1.


Evidence for fatty acids mediating CL 316,243-induced reductions in blood glucose in mice.

MacPherson RE, Castellani L, Beaudoin MS, Wright DC.

Am J Physiol Endocrinol Metab. 2014 Oct 1;307(7):E563-70. doi: 10.1152/ajpendo.00287.2014. Epub 2014 Aug 5.


Feeding butter with elevated content of trans-10, cis-12 conjugated linoleic acid to lean rats does not impair glucose tolerance or muscle insulin response.

Stefanson A, Hopkins LE, AlZahal O, Ritchie IR, MacDonald T, Wright DC, McBride BW, Dyck DJ.

Lipids Health Dis. 2014 Jun 23;13:101. doi: 10.1186/1476-511X-13-101.


The day/night proteome in the murine heart.

Podobed P, Pyle WG, Ackloo S, Alibhai FJ, Tsimakouridze EV, Ratcliffe WF, Mackay A, Simpson J, Wright DC, Kirby GM, Young ME, Martino TA.

Am J Physiol Regul Integr Comp Physiol. 2014 Jul 15;307(2):R121-37.


Adiponectin is sufficient, but not required, for exercise-induced increases in the expression of skeletal muscle mitochondrial enzymes.

Ritchie IR, MacDonald TL, Wright DC, Dyck DJ.

J Physiol. 2014 Jun 15;592(12):2653-65. doi: 10.1113/jphysiol.2014.273680. Epub 2014 Mar 31.

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