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Items: 1 to 50 of 123

1.

Intraosseous injection of rhBMP-2/calcium phosphate matrix improves bone structure and strength in the proximal aspect of the femur in chronic ovariectomized nonhuman primates.

Seeherman HJ, Li XJ, Smith E, Parkington J, Li R, Wozney JM.

J Bone Joint Surg Am. 2013 Jan 2;95(1):36-47. doi: 10.2106/JBJS.K.00668.

PMID:
23283371
2.

rhBMP-2/calcium phosphate matrix induces bone formation while limiting transient bone resorption in a nonhuman primate core defect model.

Seeherman HJ, Li XJ, Smith E, Wozney JM.

J Bone Joint Surg Am. 2012 Oct 3;94(19):1765-76. doi: 10.2106/JBJS.K.00523.

PMID:
23032587
3.

Evaluation of implants coated with recombinant human bone morphogenetic protein-2 and vacuum-dried using the critical-size supraalveolar peri-implant defect model in dogs.

Decker JF, Lee J, Cortella CA, Polimeni G, Rohrer MD, Wozney JM, Hall J, Susin C, Wikesjö UM.

J Periodontol. 2010 Dec;81(12):1839-49. doi: 10.1902/jop.2010.100220. Epub 2010 Jul 14.

PMID:
20629551
4.

Evaluation of implants coated with rhBMP-2 using two different coating strategies: a critical-size supraalveolar peri-implant defect study in dogs.

Lee J, Decker JF, Polimeni G, Cortella CA, Rohrer MD, Wozney JM, Hall J, Susin C, Wikesjö UM.

J Clin Periodontol. 2010 Jun;37(6):582-90. doi: 10.1111/j.1600-051X.2010.01557.x. Epub 2010 Mar 23.

PMID:
20345393
5.

rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model.

Seeherman HJ, Li XJ, Bouxsein ML, Wozney JM.

J Bone Joint Surg Am. 2010 Feb;92(2):411-26. doi: 10.2106/JBJS.H.01732.

PMID:
20124069
6.

Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: histologic observations.

Wikesjö UM, Qahash M, Polimeni G, Susin C, Shanaman RH, Rohrer MD, Wozney JM, Hall J.

J Clin Periodontol. 2008 Nov;35(11):1001-10. doi: 10.1111/j.1600-051X.2008.01321.x.

PMID:
18976397
7.

Bone formation at recombinant human bone morphogenetic protein-2-coated titanium implants in the posterior maxilla (Type IV bone) in non-human primates.

Wikesjö UM, Huang YH, Xiropaidis AV, Sorensen RG, Rohrer MD, Prasad HS, Wozney JM, Hall J.

J Clin Periodontol. 2008 Nov;35(11):992-1000. doi: 10.1111/j.1600-051X.2008.01322.x.

PMID:
18976396
8.

Bone formation at recombinant human bone morphogenetic protein-2-coated titanium implants in the posterior mandible (Type II bone) in dogs.

Wikesjö UM, Xiropaidis AV, Qahash M, Lim WH, Sorensen RG, Rohrer MD, Wozney JM, Hall J.

J Clin Periodontol. 2008 Nov;35(11):985-91. doi: 10.1111/j.1600-051X.2008.01318.x.

PMID:
18976395
9.

rhBMP-12 accelerates healing of rotator cuff repairs in a sheep model.

Seeherman HJ, Archambault JM, Rodeo SA, Turner AS, Zekas L, D'Augusta D, Li XJ, Smith E, Wozney JM.

J Bone Joint Surg Am. 2008 Oct;90(10):2206-19. doi: 10.2106/JBJS.G.00742.

PMID:
18829919
10.

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy.

Wagner KR, Fleckenstein JL, Amato AA, Barohn RJ, Bushby K, Escolar DM, Flanigan KM, Pestronk A, Tawil R, Wolfe GI, Eagle M, Florence JM, King WM, Pandya S, Straub V, Juneau P, Meyers K, Csimma C, Araujo T, Allen R, Parsons SA, Wozney JM, Lavallie ER, Mendell JR.

Ann Neurol. 2008 May;63(5):561-71. doi: 10.1002/ana.21338.

PMID:
18335515
11.

Surface-etching enhances titanium implant osseointegration in newly formed (rhBMP-2-induced) and native bone.

Qahash M, Hardwick WR, Rohrer MD, Wozney JM, Wikesjö UM.

Int J Oral Maxillofac Implants. 2007 May-Jun;22(3):472-7.

PMID:
17622015
12.

Role of RGM coreceptors in bone morphogenetic protein signaling.

Halbrooks PJ, Ding R, Wozney JM, Bain G.

J Mol Signal. 2007 Jul 5;2:4.

13.

Bone formation at rhBMP-2-coated titanium implants in the rat ectopic model.

Hall J, Sorensen RG, Wozney JM, Wikesjö UM.

J Clin Periodontol. 2007 May;34(5):444-51.

PMID:
17448048
14.

Bone reconstruction following implantation of rhBMP-2 and guided bone regeneration in canine alveolar ridge defects.

Jovanovic SA, Hunt DR, Bernard GW, Spiekermann H, Wozney JM, Wikesjö UM.

Clin Oral Implants Res. 2007 Apr;18(2):224-30.

PMID:
17348887
15.

rhBMP-2 delivered in a calcium phosphate cement accelerates bridging of critical-sized defects in rabbit radii.

Seeherman HJ, Azari K, Bidic S, Rogers L, Li XJ, Hollinger JO, Wozney JM.

J Bone Joint Surg Am. 2006 Jul;88(7):1553-65.

PMID:
16818982
16.

Engineering new bone with bone morphogenic proteins.

Wozney JM.

Ann Endocrinol (Paris). 2006 Apr;67(2):180-1. No abstract available.

PMID:
16639375
17.

rhBMP-2/calcium phosphate matrix accelerates osteotomy-site healing in a nonhuman primate model at multiple treatment times and concentrations.

Seeherman H, Li R, Bouxsein M, Kim H, Li XJ, Smith-Adaline EA, Aiolova M, Wozney JM.

J Bone Joint Surg Am. 2006 Jan;88(1):144-60.

PMID:
16391260
18.

Observations on healing following endodontic surgery in nonhuman primates (Macaca fascicularis): effects of rhBMP-2.

Bergenholtz G, Wikesjö UM, Sorensen RG, Xiropaidis AV, Wozney JM.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jan;101(1):116-25. Epub 2005 Nov 2.

PMID:
16360616
19.

Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter.

Lee MH, Kim YJ, Yoon WJ, Kim JI, Kim BG, Hwang YS, Wozney JM, Chi XZ, Bae SC, Choi KY, Cho JY, Choi JY, Ryoo HM.

J Biol Chem. 2005 Oct 21;280(42):35579-87. Epub 2005 Aug 22.

20.

Evaluation of recombinant human bone morphogenetic protein-2 on the repair of alveolar ridge defects in baboons.

Miranda DA, Blumenthal NM, Sorensen RG, Wozney JM, Wikesjö UM.

J Periodontol. 2005 Feb;76(2):210-20.

PMID:
15974844
21.

Delivery of bone morphogenetic proteins for orthopedic tissue regeneration.

Seeherman H, Wozney JM.

Cytokine Growth Factor Rev. 2005 Jun;16(3):329-45. Review.

PMID:
15936978
22.

Protein-based tissue engineering in bone and cartilage repair.

Wozney JM, Seeherman HJ.

Curr Opin Biotechnol. 2004 Oct;15(5):392-8. Review.

PMID:
15464367
23.

Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2.

Kim YJ, Lee MH, Wozney JM, Cho JY, Ryoo HM.

J Biol Chem. 2004 Dec 3;279(49):50773-80. Epub 2004 Sep 21.

24.

Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy-site healing in a nonhuman primate model.

Seeherman HJ, Bouxsein M, Kim H, Li R, Li XJ, Aiolova M, Wozney JM.

J Bone Joint Surg Am. 2004 Sep;86-A(9):1961-72.

PMID:
15342759
25.

Periodontal repair in dogs: evaluation of a bioresorbable calcium phosphate cement (Ceredex) as a carrier for rhBMP-2.

Sorensen RG, Wikesjö UM, Kinoshita A, Wozney JM.

J Clin Periodontol. 2004 Sep;31(9):796-804.

PMID:
15312104
26.

Periodontal repair in dogs: effect of recombinant human bone morphogenetic protein-12 (rhBMP-12) on regeneration of alveolar bone and periodontal attachment.

Wikesjö UM, Sorensen RG, Kinoshita A, Jian Li X, Wozney JM.

J Clin Periodontol. 2004 Aug;31(8):662-70. Review.

PMID:
15257745
27.

Effect of recombinant human bone morphogenetic protein-12 (rhBMP-12) on regeneration of periodontal attachment following tooth replantation in dogs.

Sorensen RG, Polimeni G, Kinoshita A, Wozney JM, Wikesjö UM.

J Clin Periodontol. 2004 Aug;31(8):654-61.

PMID:
15257744
28.

Long-term functional loading of dental implants in rhBMP-2 induced bone. A histologic study in the canine ridge augmentation model.

Jovanovic SA, Hunt DR, Bernard GW, Spiekermann H, Nishimura R, Wozney JM, Wikesjö UM.

Clin Oral Implants Res. 2003 Dec;14(6):793-803.

PMID:
15015957
29.

rhBMP-2 significantly enhances guided bone regeneration.

Wikesjö UM, Qahash M, Thomson RC, Cook AD, Rohrer MD, Wozney JM, Hardwick WR.

Clin Oral Implants Res. 2004 Apr;15(2):194-204.

PMID:
15008931
30.

Characterization of a calcium phosphate-based matrix for rhBMP-2.

Kim HD, Wozney JM, Li RH.

Methods Mol Biol. 2004;238:49-64. No abstract available.

PMID:
14970438
31.

Locally delivered rhBMP-2 enhances bone ingrowth and gap healing in a canine model.

Sumner DR, Turner TM, Urban RM, Turek T, Seeherman H, Wozney JM.

J Orthop Res. 2004 Jan;22(1):58-65.

32.

rhBMP-2 injected in a calcium phosphate paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model.

Li RH, Bouxsein ML, Blake CA, D'Augusta D, Kim H, Li XJ, Wozney JM, Seeherman HJ.

J Orthop Res. 2003 Nov;21(6):997-1004.

33.
34.

BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2.

Lee MH, Kwon TG, Park HS, Wozney JM, Ryoo HM.

Biochem Biophys Res Commun. 2003 Sep 26;309(3):689-94.

PMID:
12963046
35.

A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair.

Einhorn TA, Majeska RJ, Mohaideen A, Kagel EM, Bouxsein ML, Turek TJ, Wozney JM.

J Bone Joint Surg Am. 2003 Aug;85-A(8):1425-35.

PMID:
12925621
36.

Effect of recombinant human bone morphogenetic protein-2 in dehiscence defects with non-submerged immediate implants: an experimental study in Cynomolgus monkeys.

Hanisch O, Sorensen RG, Kinoshita A, Spiekermann H, Wozney JM, Wikesjö UM.

J Periodontol. 2003 May;74(5):648-57.

PMID:
12816297
37.

Periodontal repair in dogs: evaluation of a bioabsorbable space-providing macroporous membrane with recombinant human bone morphogenetic protein-2.

Wikesjö UM, Lim WH, Thomson RC, Cook AD, Wozney JM, Hardwick WR.

J Periodontol. 2003 May;74(5):635-47.

PMID:
12816296
38.

BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression.

Lee MH, Kim YJ, Kim HJ, Park HD, Kang AR, Kyung HM, Sung JH, Wozney JM, Kim HJ, Ryoo HM.

J Biol Chem. 2003 Sep 5;278(36):34387-94. Epub 2003 Jun 18.

39.

Engineering what comes naturally.

Wozney JM, Li RH.

Nat Biotechnol. 2003 May;21(5):506-8. No abstract available.

PMID:
12721574
40.

RhBMP-2/alphaBSM induces significant vertical alveolar ridge augmentation and dental implant osseointegration.

Wikesjö UM, Sorensen RG, Kinoshita A, Wozney JM.

Clin Implant Dent Relat Res. 2002;4(4):174-82.

PMID:
12685792
41.
42.

Bone repair following recombinant human bone morphogenetic protein-2 stimulated periodontal regeneration.

Selvig KA, Sorensen RG, Wozney JM, Wikesjö UM.

J Periodontol. 2002 Sep;73(9):1020-9.

PMID:
12296587
43.

Overview of bone morphogenetic proteins.

Wozney JM.

Spine (Phila Pa 1976). 2002 Aug 15;27(16 Suppl 1):S2-8. Review.

PMID:
12205411
44.

Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis.

Li G, Bouxsein ML, Luppen C, Li XJ, Wood M, Seeherman HJ, Wozney JM, Simpson H.

J Orthop Res. 2002 Jul;20(4):779-88.

45.

Synthetic thermoreversible polymers are compatible with osteoinductive activity of recombinant human bone morphogenetic protein 2.

Gao TJ, Kousinioris NA, Wozney JM, Winn S, Uludag H.

Tissue Eng. 2002 Jul;8(3):429-40.

PMID:
12167229
46.

Peri-implant bone regeneration using recombinant human bone morphogenetic protein-2 in a canine model: a dose-response study.

Tatakis DN, Koh A, Jin L, Wozney JM, Rohrer MD, Wikesjö UM.

J Periodontal Res. 2002 Apr;37(2):93-100.

PMID:
12009189
47.

Effect of recombinant human bone morphogenetic protein-2/absorbable collagen sponge (rhBMP-2/ACS) on healing in 3-wall intrabony defects in dogs.

Choi SH, Kim CK, Cho KS, Huh JS, Sorensen RG, Wozney JM, Wikesjö UM.

J Periodontol. 2002 Jan;73(1):63-72.

PMID:
11852905
48.

Recombinant human bone morphogenetic protein-2 enhances osteotomy healing in glucocorticoid-treated rabbits.

Luppen CA, Blake CA, Ammirati KM, Stevens ML, Seeherman HJ, Wozney JM, Bouxsein ML.

J Bone Miner Res. 2002 Feb;17(2):301-10.

49.

Recombinant human bone morphogenetic protein-2 accelerates healing in a rabbit ulnar osteotomy model.

Bouxsein ML, Turek TJ, Blake CA, D'Augusta D, Li X, Stevens M, Seeherman HJ, Wozney JM.

J Bone Joint Surg Am. 2001 Aug;83-A(8):1219-30.

PMID:
11507131
50.

Delivering on the promise of bone morphogenetic proteins.

Li RH, Wozney JM.

Trends Biotechnol. 2001 Jul;19(7):255-65. Review.

PMID:
11412949

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