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Items: 9

1.

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

Wedge DC, Gundem G, Mitchell T, Woodcock DJ, Martincorena I, Ghori M, Zamora J, Butler A, Whitaker H, Kote-Jarai Z, Alexandrov LB, Van Loo P, Massie CE, Dentro S, Warren AY, Verrill C, Berney DM, Dennis N, Merson S, Hawkins S, Howat W, Lu YJ, Lambert A, Kay J, Kremeyer B, Karaszi K, Luxton H, Camacho N, Marsden L, Edwards S, Matthews L, Bo V, Leongamornlert D, McLaren S, Ng A, Yu Y, Zhang H, Dadaev T, Thomas S, Easton DF, Ahmed M, Bancroft E, Fisher C, Livni N, Nicol D, Tavaré S, Gill P, Greenman C, Khoo V, Van As N, Kumar P, Ogden C, Cahill D, Thompson A, Mayer E, Rowe E, Dudderidge T, Gnanapragasam V, Shah NC, Raine K, Jones D, Menzies A, Stebbings L, Teague J, Hazell S, Corbishley C; CAMCAP Study Group, de Bono J, Attard G, Isaacs W, Visakorpi T, Fraser M, Boutros PC, Bristow RG, Workman P, Sander C; TCGA Consortium, Hamdy FC, Futreal A, McDermott U, Al-Lazikani B, Lynch AG, Bova GS, Foster CS, Brewer DS, Neal DE, Cooper CS, Eeles RA.

Nat Genet. 2018 Apr 16. doi: 10.1038/s41588-018-0086-z. [Epub ahead of print]

PMID:
29662167
2.

The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis.

Pavlaki I, Alammari F, Sun B, Clark N, Sirey T, Lee S, Woodcock DJ, Ponting CP, Szele FG, Vance KW.

EMBO J. 2018 Apr 16. pii: e98219. doi: 10.15252/embj.201798219. [Epub ahead of print]

3.

Lineage-specific plasmid acquisition and the evolution of specialized pathogens in Bacillus thuringiensis and the Bacillus cereus group.

Méric G, Mageiros L, Pascoe B, Woodcock DJ, Mourkas E, Lamble S, Bowden R, Jolley KA, Raymond B, Sheppard SK.

Mol Ecol. 2018 Mar 6. doi: 10.1111/mec.14546. [Epub ahead of print]

PMID:
29509989
4.

Genomic plasticity and rapid host switching can promote the evolution of generalism: a case study in the zoonotic pathogen Campylobacter.

Woodcock DJ, Krusche P, Strachan NJC, Forbes KJ, Cohan FM, Méric G, Sheppard SK.

Sci Rep. 2017 Aug 29;7(1):9650. doi: 10.1038/s41598-017-09483-9.

5.

Conserved Cis-Regulatory Modules Control Robustness in Msx1 Expression at Single-Cell Resolution.

Vance KW, Woodcock DJ, Reid JE, Bretschneider T, Ott S, Koentges G.

Genome Biol Evol. 2015 Sep 4;7(9):2762-78. doi: 10.1093/gbe/evv179.

6.

A hierarchical model of transcriptional dynamics allows robust estimation of transcription rates in populations of single cells with variable gene copy number.

Woodcock DJ, Vance KW, Komorowski M, Koentges G, Finkenstädt B, Rand DA.

Bioinformatics. 2013 Jun 15;29(12):1519-25. doi: 10.1093/bioinformatics/btt201. Epub 2013 May 14.

7.

Evidence for phenotypic plasticity among multihost Campylobacter jejuni and C. coli lineages, obtained using ribosomal multilocus sequence typing and Raman spectroscopy.

Read DS, Woodcock DJ, Strachan NJ, Forbes KJ, Colles FM, Maiden MC, Clifton-Hadley F, Ridley A, Vidal A, Rodgers J, Whiteley AS, Sheppard SK.

Appl Environ Microbiol. 2013 Feb;79(3):965-73. doi: 10.1128/AEM.02521-12. Epub 2012 Nov 30.

8.

Dynamic analysis of stochastic transcription cycles.

Harper CV, Finkenstädt B, Woodcock DJ, Friedrichsen S, Semprini S, Ashall L, Spiller DG, Mullins JJ, Rand DA, Davis JR, White MR.

PLoS Biol. 2011 Apr;9(4):e1000607. doi: 10.1371/journal.pbio.1000607. Epub 2011 Apr 12.

9.

Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells.

Turner DA, Paszek P, Woodcock DJ, Nelson DE, Horton CA, Wang Y, Spiller DG, Rand DA, White MR, Harper CV.

J Cell Sci. 2010 Aug 15;123(Pt 16):2834-43. doi: 10.1242/jcs.069641. Epub 2010 Jul 27.

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