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Items: 1 to 50 of 248

1.

Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors.

Snowden AW, Zhang L, Urnov F, Dent C, Jouvenot Y, Zhong X, Rebar EJ, Jamieson AC, Zhang HS, Tan S, Case CC, Pabo CO, Wolffe AP, Gregory PD.

Cancer Res. 2003 Dec 15;63(24):8968-76.

2.

Purification of the MeCP2/histone deacetylase complex from Xenopus laevis.

Jones PL, Wade PA, Wolffe AP.

Methods Mol Biol. 2001;181:297-307.

PMID:
12843459
3.

Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors.

Jouvenot Y, Ginjala V, Zhang L, Liu PQ, Oshimura M, Feinberg AP, Wolffe AP, Ohlsson R, Gregory PD.

Gene Ther. 2003 Mar;10(6):513-22.

PMID:
12621455
4.

Profiling methyl-CpG specific determinants on transcriptionally silent chromatin.

El-Osta A, Baker EK, Wolffe AP.

Mol Biol Rep. 2001;28(4):209-15.

PMID:
12153140
5.
6.

Purification of MeCP2-containing deacetylase from Xenopus laevis.

Jones PL, Wade PA, Wolffe AP.

Methods Mol Biol. 2002;200:131-41. No abstract available.

PMID:
11951648
7.

Activation of vascular endothelial growth factor A transcription in tumorigenic glioblastoma cell lines by an enhancer with cell type-specific DNase I accessibility.

Liang Y, Li XY, Rebar EJ, Li P, Zhou Y, Chen B, Wolffe AP, Case CC.

J Biol Chem. 2002 May 31;277(22):20087-94. Epub 2002 Mar 23.

8.
9.
10.

Transcriptional regulation in the context of chromatin structure.

Wolffe AP.

Essays Biochem. 2001;37:45-57. Review.

PMID:
11758456
11.

Analysis of chromatin-immunopurified MeCP2-associated fragments.

El-Osta A, Wolffe AP.

Biochem Biophys Res Commun. 2001 Dec 7;289(3):733-7.

PMID:
11726209
12.

Gene-selective developmental roles of general transcription factors.

Veenstra GJ, Wolffe AP.

Trends Biochem Sci. 2001 Nov;26(11):665-71. Review.

PMID:
11701325
13.

Constitutive genomic methylation during embryonic development of Xenopus.

Veenstra GJ, Wolffe AP.

Biochim Biophys Acta. 2001 Oct 31;1521(1-3):39-44.

PMID:
11690634
14.

A Drosophila MBD family member is a transcriptional corepressor associated with specific genes.

Ballestar E, Pile LA, Wassarman DA, Wolffe AP, Wade PA.

Eur J Biochem. 2001 Oct;268(20):5397-406.

15.

Above and within the genome: epigenetics past and present.

Urnov FD, Wolffe AP.

J Mammary Gland Biol Neoplasia. 2001 Apr;6(2):153-67. Review.

PMID:
11501576
16.

Chromatin remodeling by the thyroid hormone receptor in regulation of the thyroid-stimulating hormone alpha-subunit promoter.

Collingwood TN, Urnov FD, Chatterjee VK, Wolffe AP.

J Biol Chem. 2001 Sep 7;276(36):34227-34. Epub 2001 Jul 13.

17.

Chromatin structure and phaseolin gene regulation.

Li G, Chandrasekharan MB, Wolffe AP, Hall TC.

Plant Mol Biol. 2001 May;46(2):121-9. Review.

PMID:
11442053
18.

ReCoGnizing methylated DNA.

Wade PA, Wolffe AP.

Nat Struct Biol. 2001 Jul;8(7):575-7. No abstract available.

PMID:
11427881
19.

Chromatin remodeling and transcriptional activation: the cast (in order of appearance).

Urnov FD, Wolffe AP.

Oncogene. 2001 May 28;20(24):2991-3006. Review.

20.

Chromatin remodeling: why it is important in cancer.

Wolffe AP.

Oncogene. 2001 May 28;20(24):2988-90. Review.

21.

Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia.

Magdinier F, Wolffe AP.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):4990-5. Epub 2001 Apr 17.

22.

Programming the transcriptional state of replicating methylated dna.

Stunkel W, Ait-Si-Ali S, Jones PL, Wolffe AP.

J Biol Chem. 2001 Jun 8;276(23):20743-9. Epub 2001 Mar 6.

23.

An array of positioned nucleosomes potentiates thyroid hormone receptor action in vivo.

Urnov FD, Wolffe AP.

J Biol Chem. 2001 Jun 8;276(23):19753-61. Epub 2001 Mar 23.

24.

DNA methylation in health and disease.

Robertson KD, Wolffe AP.

Nat Rev Genet. 2000 Oct;1(1):11-9. Review.

PMID:
11262868
25.

Nuclear visions: functional flexibility from structural instability.

Wolffe AP, Hansen JC.

Cell. 2001 Mar 9;104(5):631-4. Review. No abstract available.

26.

Molecular mechanisms of corepressor function.

Urnov FD, Wolffe AP, Guschin D.

Curr Top Microbiol Immunol. 2001;254:1-33. Review. No abstract available.

PMID:
11190568
27.

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

Liu PQ, Rebar EJ, Zhang L, Liu Q, Jamieson AC, Liang Y, Qi H, Li PX, Chen B, Mendel MC, Zhong X, Lee YL, Eisenberg SP, Spratt SK, Case CC, Wolffe AP.

J Biol Chem. 2001 Apr 6;276(14):11323-34. Epub 2001 Jan 5.

28.

A necessary good: nuclear hormone receptors and their chromatin templates.

Urnov FD, Wolffe AP.

Mol Endocrinol. 2001 Jan;15(1):1-16. Review. No abstract available.

PMID:
11145735
29.

Distinct roles for TBP and TBP-like factor in early embryonic gene transcription in Xenopus.

Veenstra GJ, Weeks DL, Wolffe AP.

Science. 2000 Dec 22;290(5500):2312-5.

30.

Methyl-CpG-binding proteins. Targeting specific gene repression.

Ballestar E, Wolffe AP.

Eur J Biochem. 2001 Jan;268(1):1-6. Review.

31.
32.

Histone deacetylase activity is required for the induction of the MyoD muscle cell lineage in Xenopus.

Steinbac OC, Wolffe AP, Rupp RA.

Biol Chem. 2000 Sep-Oct;381(9-10):1013-6.

PMID:
11076034
33.

Functional consequences of Rett syndrome mutations on human MeCP2.

Yusufzai TM, Wolffe AP.

Nucleic Acids Res. 2000 Nov 1;28(21):4172-9.

34.

Active remodeling of somatic nuclei in egg cytoplasm by the nucleosomal ATPase ISWI.

Kikyo N, Wade PA, Guschin D, Ge H, Wolffe AP.

Science. 2000 Sep 29;289(5488):2360-2.

35.

Co-repressor complexes and remodelling chromatin for repression.

Wolffe AP, Urnov FD, Guschin D.

Biochem Soc Trans. 2000;28(4):379-86. Review.

PMID:
10961924
36.

Multiple ISWI ATPase complexes from xenopus laevis. Functional conservation of an ACF/CHRAC homolog.

Guschin D, Geiman TM, Kikyo N, Tremethick DJ, Wolffe AP, Wade PA.

J Biol Chem. 2000 Nov 10;275(45):35248-55.

37.

Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-erbA yields a chromatin infrastructure-dependent transcriptional repression pathway.

Urnov FD, Yee J, Sachs L, Collingwood TN, Bauer A, Beug H, Shi YB, Wolffe AP.

EMBO J. 2000 Aug 1;19(15):4074-90.

38.

Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene.

Zhang L, Spratt SK, Liu Q, Johnstone B, Qi H, Raschke EE, Jamieson AC, Rebar EJ, Wolffe AP, Case CC.

J Biol Chem. 2000 Oct 27;275(43):33850-60.

39.

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters.

Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP.

Nat Genet. 2000 Jul;25(3):338-42.

PMID:
10888886
40.

HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.

Lau OD, Kundu TK, Soccio RE, Ait-Si-Ali S, Khalil EM, Vassilev A, Wolffe AP, Nakatani Y, Roeder RG, Cole PA.

Mol Cell. 2000 Mar;5(3):589-95.

41.

Transcriptional control: imprinting insulation.

Wolffe AP.

Curr Biol. 2000 Jun 15;10(12):R463-5. Review.

42.

Determinants of vitellogenin B1 promoter architecture. HNF3 and estrogen responsive transcription within chromatin.

Robyr D, Gegonne A, Wolffe AP, Wahli W.

J Biol Chem. 2000 Sep 8;275(36):28291-300.

44.

ATP-Dependent histone octamer mobilization and histone deacetylation mediated by the Mi-2 chromatin remodeling complex.

Guschin D, Wade PA, Kikyo N, Wolffe AP.

Biochemistry. 2000 May 9;39(18):5238-45.

PMID:
10819992
45.

Review: chromatin structural features and targets that regulate transcription.

Wolffe AP, Guschin D.

J Struct Biol. 2000 Apr;129(2-3):102-22. Review.

PMID:
10806063
46.

Analysis of linker histone binding to mono- and dinucleosomes.

Chandler S, Wolffe AP.

Methods Mol Biol. 1999;119:103-12. Review. No abstract available.

PMID:
10804506
47.

Functional delineation of three groups of the ATP-dependent family of chromatin remodeling enzymes.

Boyer LA, Logie C, Bonte E, Becker PB, Wade PA, Wolffe AP, Wu C, Imbalzano AN, Peterson CL.

J Biol Chem. 2000 Jun 23;275(25):18864-70.

49.

Creating molecular clues to uncover gene function.

Wolffe AP, Leblanc BP.

Nat Biotechnol. 2000 Apr;18(4):379-80. No abstract available.

PMID:
10748513
50.

Nuclear hormone receptor coregulators in action: diversity for shared tasks.

Robyr D, Wolffe AP, Wahli W.

Mol Endocrinol. 2000 Mar;14(3):329-47. Review. No abstract available.

PMID:
10707952

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