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Items: 20

1.

Colonic transcriptional response to 1α,25(OH)2 vitamin D3 in African- and European-Americans.

Alleyne D, Witonsky DB, Mapes B, Nakagome S, Sommars M, Hong E, Muckala KA, Di Rienzo A, Kupfer SS.

J Steroid Biochem Mol Biol. 2017 Apr;168:49-59. doi: 10.1016/j.jsbmb.2017.02.001. Epub 2017 Feb 3.

2.

Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells.

Kariuki SN, Maranville JC, Baxter SS, Jeong C, Nakagome S, Hrusch CL, Witonsky DB, Sperling AI, Di Rienzo A.

PLoS One. 2016 Jul 25;11(7):e0159779. doi: 10.1371/journal.pone.0159779. eCollection 2016.

3.

Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc.

Jeong C, Ozga AT, Witonsky DB, Malmström H, Edlund H, Hofman CA, Hagan RW, Jakobsson M, Lewis CM, Aldenderfer MS, Di Rienzo A, Warinner C.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7485-90. doi: 10.1073/pnas.1520844113. Epub 2016 Jun 20.

4.

Patterns of Transcriptional Response to 1,25-Dihydroxyvitamin D3 and Bacterial Lipopolysaccharide in Primary Human Monocytes.

Kariuki SN, Blischak JD, Nakagome S, Witonsky DB, Di Rienzo A.

G3 (Bethesda). 2016 May 3;6(5):1345-55. doi: 10.1534/g3.116.028712.

5.

Admixture facilitates genetic adaptations to high altitude in Tibet.

Jeong C, Alkorta-Aranburu G, Basnyat B, Neupane M, Witonsky DB, Pritchard JK, Beall CM, Di Rienzo A.

Nat Commun. 2014;5:3281. doi: 10.1038/ncomms4281.

6.

Genetic mapping with multiple levels of phenotypic information reveals determinants of lymphocyte glucocorticoid sensitivity.

Maranville JC, Baxter SS, Witonsky DB, Chase MA, Di Rienzo A.

Am J Hum Genet. 2013 Oct 3;93(4):735-43. doi: 10.1016/j.ajhg.2013.08.005. Epub 2013 Sep 19.

7.

Genetic, functional and molecular features of glucocorticoid receptor binding.

Luca F, Maranville JC, Richards AL, Witonsky DB, Stephens M, Di Rienzo A.

PLoS One. 2013 Apr 30;8(4):e61654. doi: 10.1371/journal.pone.0061654. Print 2013.

8.

The genetic architecture of adaptations to high altitude in Ethiopia.

Alkorta-Aranburu G, Beall CM, Witonsky DB, Gebremedhin A, Pritchard JK, Di Rienzo A.

PLoS Genet. 2012;8(12):e1003110. doi: 10.1371/journal.pgen.1003110. Epub 2012 Dec 6.

9.

Reconstructing Native American population history.

Reich D, Patterson N, Campbell D, Tandon A, Mazieres S, Ray N, Parra MV, Rojas W, Duque C, Mesa N, García LF, Triana O, Blair S, Maestre A, Dib JC, Bravi CM, Bailliet G, Corach D, Hünemeier T, Bortolini MC, Salzano FM, Petzl-Erler ML, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S, Tusié-Luna T, Riba L, Rodríguez-Cruz M, Lopez-Alarcón M, Coral-Vazquez R, Canto-Cetina T, Silva-Zolezzi I, Fernandez-Lopez JC, Contreras AV, Jimenez-Sanchez G, Gómez-Vázquez MJ, Molina J, Carracedo A, Salas A, Gallo C, Poletti G, Witonsky DB, Alkorta-Aranburu G, Sukernik RI, Osipova L, Fedorova SA, Vasquez R, Villena M, Moreau C, Barrantes R, Pauls D, Excoffier L, Bedoya G, Rothhammer F, Dugoujon JM, Larrouy G, Klitz W, Labuda D, Kidd J, Kidd K, Di Rienzo A, Freimer NB, Price AL, Ruiz-Linares A.

Nature. 2012 Aug 16;488(7411):370-4. doi: 10.1038/nature11258. Erratum in: Nature. 2012 Nov 8;491(7423):288.

10.

Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes.

Maranville JC, Luca F, Richards AL, Wen X, Witonsky DB, Baxter S, Stephens M, Di Rienzo A.

PLoS Genet. 2011 Jul;7(7):e1002162. doi: 10.1371/journal.pgen.1002162. Epub 2011 Jul 7.

11.

A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.

Sun C, Huo D, Southard C, Nemesure B, Hennis A, Cristina Leske M, Wu SY, Witonsky DB, Olopade OI, Di Rienzo A.

Hum Genet. 2011 Dec;130(6):767-75. doi: 10.1007/s00439-011-1025-6. Epub 2011 Jun 10.

12.

A reduced representation approach to population genetic analyses and applications to human evolution.

Luca F, Hudson RR, Witonsky DB, Di Rienzo A.

Genome Res. 2011 Jul;21(7):1087-98. doi: 10.1101/gr.119792.110. Epub 2011 May 31.

13.

Adaptations to climate-mediated selective pressures in humans.

Hancock AM, Witonsky DB, Alkorta-Aranburu G, Beall CM, Gebremedhin A, Sukernik R, Utermann G, Pritchard JK, Coop G, Di Rienzo A.

PLoS Genet. 2011 Apr;7(4):e1001375. doi: 10.1371/journal.pgen.1001375. Epub 2011 Apr 21.

14.

SNP discovery, expression and cis-regulatory variation in the UGT2B genes.

Sun C, Southard C, Huo D, Hernandez RD, Witonsky DB, Olopade OI, Di Rienzo A.

Pharmacogenomics J. 2012 Aug;12(4):287-96. doi: 10.1038/tpj.2011.2. Epub 2011 Mar 1.

15.

Natural selection and functional genetic variation in the p53 pathway.

Sucheston L, Witonsky DB, Hastings D, Yildiz O, Clark VJ, Di Rienzo A, Onel K.

Hum Mol Genet. 2011 Apr 15;20(8):1502-8. doi: 10.1093/hmg/ddr028. Epub 2011 Jan 25.

16.

Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.

Sun C, Southard C, Witonsky DB, Kittler R, Di Rienzo A.

PLoS Genet. 2010 Oct 28;6(10):e1001178. doi: 10.1371/journal.pgen.1001178.

17.

Adaptations to new environments in humans: the role of subtle allele frequency shifts.

Hancock AM, Alkorta-Aranburu G, Witonsky DB, Di Rienzo A.

Philos Trans R Soc Lond B Biol Sci. 2010 Aug 27;365(1552):2459-68. doi: 10.1098/rstb.2010.0032.

18.

Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency.

Hancock AM, Witonsky DB, Ehler E, Alkorta-Aranburu G, Beall C, Gebremedhin A, Sukernik R, Utermann G, Pritchard J, Coop G, Di Rienzo A.

Proc Natl Acad Sci U S A. 2010 May 11;107 Suppl 2:8924-30. doi: 10.1073/pnas.0914625107. Epub 2010 May 5.

19.

Allelic imbalance (AI) identifies novel tissue-specific cis-regulatory variation for human UGT2B15.

Sun C, Southard C, Witonsky DB, Olopade OI, Di Rienzo A.

Hum Mutat. 2010 Jan;31(1):99-107. doi: 10.1002/humu.21145.

20.

Adaptations to climate in candidate genes for common metabolic disorders.

Hancock AM, Witonsky DB, Gordon AS, Eshel G, Pritchard JK, Coop G, Di Rienzo A.

PLoS Genet. 2008 Feb;4(2):e32. doi: 10.1371/journal.pgen.0040032.

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