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Items: 1 to 50 of 453

1.

NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS.

Ouali Alami N, Schurr C, Olde Heuvel F, Tang L, Li Q, Tasdogan A, Kimbara A, Nettekoven M, Ottaviani G, Raposo C, Röver S, Rogers-Evans M, Rothenhäusler B, Ullmer C, Fingerle J, Grether U, Knuesel I, Boeckers TM, Ludolph A, Wirth T, Roselli F, Baumann B.

EMBO J. 2018 Jun 6. pii: e98697. doi: 10.15252/embj.201798697. [Epub ahead of print]

2.

High-Grade Osteosarcoma of the Foot: Presentation, Treatment, Prognostic Factors, and Outcome of 23 Cooperative Osteosarcoma Study Group COSS Patients.

Schuster AJ, Kager L, Reichardt P, Baumhoer D, Csóka M, Hecker-Nolting S, Lang S, Lorenzen S, Mayer-Steinacker R, von Kalle T, Kevric M, Werner M, Windhager R, Wirth T, Bielack SS.

Sarcoma. 2018 May 2;2018:1632978. doi: 10.1155/2018/1632978. eCollection 2018.

3.

Alternative Strategies with Iodine: Fast Access to Previously Inaccessible Iodine(III) Compounds.

Hokamp T, Mollari L, Wilkins LC, Melen RL, Wirth T.

Angew Chem Int Ed Engl. 2018 May 10. doi: 10.1002/anie.201804642. [Epub ahead of print]

PMID:
29744994
4.

Multimodal management of severe herpes simplex virus encephalitis: A case report and literature review.

Todeschi J, Gubian A, Wirth T, Coca HA, Proust F, Cebula H.

Neurochirurgie. 2018 May 2. pii: S0028-3770(17)30181-9. doi: 10.1016/j.neuchi.2017.10.005. [Epub ahead of print] Review.

PMID:
29730051
5.

One-pot synthesis of diaryliodonium salts from arenes and aryl iodides with Oxone-sulfuric acid.

Soldatova N, Postnikov P, Kukurina O, Zhdankin VV, Yoshimura A, Wirth T, Yusubov MS.

Beilstein J Org Chem. 2018 Apr 12;14:849-855. doi: 10.3762/bjoc.14.70. eCollection 2018.

6.

Progressive encephalomyelitis with rigidity and myoclonus, a diagnostic challenge.

Wirth T, Kaeuffer C, Chanson JB, Echaniz-Laguna A, Renaud M, Anheim M, Schneider F, Tranchant C.

Rev Neurol (Paris). 2018 May;174(5):343-346. doi: 10.1016/j.neurol.2017.09.012. Epub 2018 Apr 22. No abstract available.

PMID:
29685428
7.

Hypervalent Iodine Reagents by Anodic Oxidation: a Powerful Green Synthesis.

Elsherbini M, Wirth T.

Chemistry. 2018 Apr 14. doi: 10.1002/chem.201801232. [Epub ahead of print]

PMID:
29655209
8.

Changing patterns of human migrations shaped the global population structure of Mycobacterium tuberculosis in France.

Barbier M, Dumitrescu O, Pichat C, Carret G, Ronnaux-Baron AS, Blasquez G, Godin-Benhaim C, Boisset S, Carricajo A, Jacomo V, Fredenucci I, Pérouse de Montclos M, Genestet C, Flandrois JP, Ader F, Supply P, Lina G, Wirth T, Rasigade JP.

Sci Rep. 2018 Apr 11;8(1):5855. doi: 10.1038/s41598-018-24034-6.

9.

Limitation of flatfoot surgery in overcorrected clubfeet after extensive surgery.

Eberhardt O, Wachowsky M, Wirth T, Fernandez Fernandez F.

Arch Orthop Trauma Surg. 2018 Apr 9. doi: 10.1007/s00402-018-2932-y. [Epub ahead of print]

PMID:
29633074
10.

[S2-Guideline: Pediatric Flat Foot].

Hell AK, Döderlein L, Eberhardt O, Hösl M, von Kalle T, Mecher F, Simon A, Stinus H, Wilken B, Wirth T.

Z Orthop Unfall. 2018 Apr 9. doi: 10.1055/s-0044-101066. [Epub ahead of print] German.

PMID:
29631308
11.

Tight regulation of FOXO1 is essential for maintenance of B-cell precursor acute lymphoblastic leukemia.

Wang F, Demir S, Gehringer F, Osswald CD, Seyfried F, Enzenmüller S, Eckhoff SM, Maier T, Holzmann K, Debatin KM, Wirth T, Meyer LH, Ushmorov A.

Blood. 2018 Apr 5. pii: blood-2017-10-813576. doi: 10.1182/blood-2017-10-813576. [Epub ahead of print]

PMID:
29622548
12.

Demographic fluctuation of community-acquired antibiotic-resistant Staphylococcus aureus lineages: potential role of flimsy antibiotic exposure.

Gustave CA, Tristan A, Martins-Simões P, Stegger M, Benito Y, Andersen PS, Bes M, Le Hir T, Diep BA, Uhlemann AC, Glaser P, Laurent F, Wirth T, Vandenesch F.

ISME J. 2018 Mar 29. doi: 10.1038/s41396-018-0110-4. [Epub ahead of print]

PMID:
29599521
13.

Medial humeral condyle fracture in childhood: a rare but often overlooked injury.

Fernandez FF, Vatlach S, Wirth T, Eberhardt O.

Eur J Trauma Emerg Surg. 2018 Feb 26. doi: 10.1007/s00068-018-0930-y. [Epub ahead of print]

PMID:
29484463
14.

Fine-tuning of FOXO3A in cHL as a survival mechanism and a hallmark of abortive plasma cell differentiation.

Osswald CD, Xie L, Guan H, Herrmann F, Pick SM, Vogel MJ, Gehringer F, Chan FC, Steidl C, Wirth T, Ushmorov A.

Blood. 2018 Apr 5;131(14):1556-1567. doi: 10.1182/blood-2017-07-795278. Epub 2018 Feb 13.

15.

Neoantigen Targeting-Dawn of a New Era in Cancer Immunotherapy?

Wirth TC, Kühnel F.

Front Immunol. 2017 Dec 19;8:1848. doi: 10.3389/fimmu.2017.01848. eCollection 2017. Review.

16.

Choledochal Cyst and Malignancy: A Plea for Lifelong Follow-Up.

Madadi-Sanjani O, Wirth TC, Kuebler JF, Petersen C, Ure BM.

Eur J Pediatr Surg. 2017 Dec 19. doi: 10.1055/s-0037-1615275. [Epub ahead of print]

PMID:
29258149
17.

A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence.

Meyer P, Maity P, Burkovski A, Schwab J, Müssel C, Singh K, Ferreira FF, Krug L, Maier HJ, Wlaschek M, Wirth T, Kestler HA, Scharffetter-Kochanek K.

PLoS Comput Biol. 2017 Dec 4;13(12):e1005741. doi: 10.1371/journal.pcbi.1005741. eCollection 2017 Dec.

18.

IKK2/NF-κB signaling protects neurons after traumatic brain injury.

Mettang M, Reichel SN, Lattke M, Palmer A, Abaei A, Rasche V, Huber-Lang M, Baumann B, Wirth T.

FASEB J. 2018 Apr;32(4):1916-1932. doi: 10.1096/fj.201700826R. Epub 2018 Jan 5.

19.

Perioperative, Spatiotemporally Coordinated Activation of T and NK Cells Prevents Recurrence of Pancreatic Cancer.

Brooks J, Fleischmann-Mundt B, Woller N, Niemann J, Ribback S, Peters K, Demir IE, Armbrecht N, Ceyhan GO, Manns MP, Wirth TC, Kubicka S, Bernhardt G, Smyth MJ, Calvisi DF, Gürlevik E, Kühnel F.

Cancer Res. 2018 Jan 15;78(2):475-488. doi: 10.1158/0008-5472.CAN-17-2415. Epub 2017 Nov 27.

PMID:
29180478
20.

Organic synthesis in flow for medicinal chemistry.

Wirth T.

Bioorg Med Chem. 2017 Dec 1;25(23):6179. doi: 10.1016/j.bmc.2017.11.013. No abstract available.

PMID:
29153554
21.

Comparing ataxias with oculomotor apraxia: a multimodal study of AOA1, AOA2 and AT focusing on video-oculography and alpha-fetoprotein.

Mariani LL, Rivaud-Péchoux S, Charles P, Ewenczyk C, Meneret A, Monga BB, Fleury MC, Hainque E, Maisonobe T, Degos B, Echaniz-Laguna A, Renaud M, Wirth T, Grabli D, Brice A, Vidailhet M, Stoppa-Lyonnet D, Dubois-d'Enghien C, Le Ber I, Koenig M, Roze E, Tranchant C, Durr A, Gaymard B, Anheim M.

Sci Rep. 2017 Nov 10;7(1):15284. doi: 10.1038/s41598-017-15127-9.

22.

Catalyst- and Supporting-Electrolyte-Free Electrosynthesis of Benzothiazoles and Thiazolopyridines in Continuous Flow.

Folgueiras-Amador AA, Qian XY, Xu HC, Wirth T.

Chemistry. 2018 Jan 9;24(2):487-491. doi: 10.1002/chem.201705016. Epub 2017 Dec 6.

PMID:
29125202
23.

Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis.

Alhaj Hussen K, Vu Manh TP, Guimiot F, Nelson E, Chabaane E, Delord M, Barbier M, Berthault C, Dulphy N, Alberdi AJ, Burlen-Defranoux O, Socié G, Bories JC, Larghero J, Vanneaux V, Verhoeyen E, Wirth T, Dalod M, Gluckman JC, Cumano A, Canque B.

Immunity. 2017 Oct 17;47(4):680-696.e8. doi: 10.1016/j.immuni.2017.09.009.

PMID:
29045900
24.

An Easy-to-Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization.

Folgueiras-Amador AA, Philipps K, Guilbaud S, Poelakker J, Wirth T.

Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15446-15450. doi: 10.1002/anie.201709717. Epub 2017 Nov 2.

25.

Recombinant LCMV Vectors Induce Protective Immunity following Homologous and Heterologous Vaccinations.

Wingerath J, Ostroumov D, Woller N, Manns MP, Pinschewer DD, Orlinger K, Berka U, Kühnel F, Wirth TC.

Mol Ther. 2017 Nov 1;25(11):2533-2545. doi: 10.1016/j.ymthe.2017.07.012. Epub 2017 Jul 20.

PMID:
28803862
26.

FOXO in B-cell lymphopoiesis and B cell neoplasia.

Ushmorov A, Wirth T.

Semin Cancer Biol. 2018 Jun;50:132-141. doi: 10.1016/j.semcancer.2017.07.008. Epub 2017 Jul 31. Review.

PMID:
28774833
27.

Electron-Deficient Chiral Lactic Acid-Based Hypervalent Iodine Reagents.

Qurban J, Elsherbini M, Wirth T.

J Org Chem. 2017 Nov 17;82(22):11872-11876. doi: 10.1021/acs.joc.7b01571. Epub 2017 Jul 31.

PMID:
28727455
28.

Severe early-onset impulsive compulsive behavior and psychosis in PLA2G6-related juvenile Parkinson's disease.

Wirth T, Weibel S, Montaut S, Bigaut K, Rudolf G, Chelly J, Tranchant C, Anheim M.

Parkinsonism Relat Disord. 2017 Aug;41:127-129. doi: 10.1016/j.parkreldis.2017.05.014. Epub 2017 May 19. No abstract available.

PMID:
28549837
29.

Pyogenic Arthritis of the Fingers and the Wrist: Can We Shorten Antimicrobial Treatment Duration?

Meier R, Wirth T, Hahn F, Vögelin E, Sendi P.

Open Forum Infect Dis. 2017 Mar 25;4(2):ofx058. doi: 10.1093/ofid/ofx058. eCollection 2017 Spring.

30.

Deciphering the causes of sporadic late-onset cerebellar ataxias: a prospective study with implications for diagnostic work.

Gebus O, Montaut S, Monga B, Wirth T, Cheraud C, Alves Do Rego C, Zinchenko I, Carré G, Hamdaoui M, Hautecloque G, Nguyen-Them L, Lannes B, Chanson JB, Lagha-Boukbiza O, Fleury MC, Devys D, Nicolas G, Rudolf G, Bereau M, Mallaret M, Renaud M, Acquaviva C, Koenig M, Koob M, Kremer S, Namer IJ, Cazeneuve C, Echaniz-Laguna A, Tranchant C, Anheim M.

J Neurol. 2017 Jun;264(6):1118-1126. doi: 10.1007/s00415-017-8500-5. Epub 2017 May 6.

PMID:
28478596
31.

Associating Liver Partition and Portal vein ligation for Staged hepatectomy after pre-operative chemotherapy.

Vondran FWR, Oldhafer F, Ringe KI, Wirth TC, Kleine M, Jäger MD, Klempnauer J, Bektas H.

ANZ J Surg. 2018 Apr;88(4):E324-E328. doi: 10.1111/ans.13944. Epub 2017 Apr 16.

PMID:
28419692
32.

Concise synthesis of artemisinin from a farnesyl diphosphate analogue.

Tang X, Demiray M, Wirth T, Allemann RK.

Bioorg Med Chem. 2018 Apr 1;26(7):1314-1319. doi: 10.1016/j.bmc.2017.03.068. Epub 2017 Apr 4.

33.

Strain-specific estimation of epidemic success provides insights into the transmission dynamics of tuberculosis.

Rasigade JP, Barbier M, Dumitrescu O, Pichat C, Carret G, Ronnaux-Baron AS, Blasquez G, Godin-Benhaim C, Boisset S, Carricajo A, Jacomo V, Fredenucci I, Pérouse de Montclos M, Flandrois JP, Ader F, Supply P, Lina G, Wirth T.

Sci Rep. 2017 Mar 28;7:45326. doi: 10.1038/srep45326.

34.

Subacute parkinsonism as a complication of Lyme disease.

Pisché G, Koob M, Wirth T, Quenardelle V, Lagha-Boukbiza O, Renaud M, Anheim M, Tranchant C.

J Neurol. 2017 May;264(5):1015-1019. doi: 10.1007/s00415-017-8472-5. Epub 2017 Mar 27. No abstract available.

PMID:
28349210
35.

An Efficient Chemoenzymatic Synthesis of Dihydroartemisinic Aldehyde.

Demiray M, Tang X, Wirth T, Faraldos JA, Allemann RK.

Angew Chem Int Ed Engl. 2017 Apr 3;56(15):4347-4350. doi: 10.1002/anie.201609557. Epub 2017 Mar 13.

36.

Optimising Terpene Synthesis with Flow Biocatalysis.

Tang X, Allemann RK, Wirth T.

European J Org Chem. 2017 Jan 10;2017(2):414-418. doi: 10.1002/ejoc.201601388. Epub 2017 Jan 13.

37.

CD40 Signaling Drives Potent Cellular Immune Responses in Heterologous Cancer Vaccinations.

Nimanong S, Ostroumov D, Wingerath J, Knocke S, Woller N, Gürlevik E, Falk CS, Manns MP, Kühnel F, Wirth TC.

Cancer Res. 2017 Apr 15;77(8):1918-1926. doi: 10.1158/0008-5472.CAN-16-2089. Epub 2017 Feb 15.

38.

Requirement of the RNA-binding protein SmpB during intracellular growth of Listeria monocytogenes.

Mraheil MA, Frantz R, Teubner L, Wendt H, Linne U, Wingerath J, Wirth T, Chakraborty T.

Int J Med Microbiol. 2017 Apr;307(3):166-173. doi: 10.1016/j.ijmm.2017.01.007. Epub 2017 Feb 1.

PMID:
28202229
39.

Surgical dislocation for pediatric and adolescent hip deformity: clinical and radiographical results at 3 years follow-up.

Guindani N, Eberhardt O, Wirth T, Surace MF, Fernandez FF.

Arch Orthop Trauma Surg. 2017 Apr;137(4):471-479. doi: 10.1007/s00402-017-2644-8. Epub 2017 Feb 14.

PMID:
28197752
40.

Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration.

Lattke M, Reichel SN, Magnutzki A, Abaei A, Rasche V, Walther P, Calado DP, Ferger B, Wirth T, Baumann B.

Mol Neurodegener. 2017 Feb 13;12(1):16. doi: 10.1186/s13024-017-0157-0.

41.

Facile One-Pot Synthesis of Diaryliodonium Salts from Arenes and Aryl Iodides with Oxone.

Soldatova N, Postnikov P, Kukurina O, Zhdankin VV, Yoshimura A, Wirth T, Yusubov MS.

ChemistryOpen. 2016 Dec 16;6(1):18-20. doi: 10.1002/open.201600129. eCollection 2017 Feb.

42.

Activation of oncogenic pathways in classical Hodgkin lymphoma by decitabine: A rationale for combination with small molecular weight inhibitors.

Swerev TM, Wirth T, Ushmorov A.

Int J Oncol. 2017 Feb;50(2):555-566. doi: 10.3892/ijo.2016.3827. Epub 2016 Dec 30.

PMID:
28035374
43.

Surveillance in cholangiocellular carcinoma.

Wirth TC, Vogel A.

Best Pract Res Clin Gastroenterol. 2016 Dec;30(6):987-999. doi: 10.1016/j.bpg.2016.11.001. Epub 2016 Nov 14. Review.

PMID:
27938792
44.

Gridded National Inventory of U.S. Methane Emissions.

Maasakkers JD, Jacob DJ, Sulprizio MP, Turner AJ, Weitz M, Wirth T, Hight C, DeFigueiredo M, Desai M, Schmeltz R, Hockstad L, Bloom AA, Bowman KW, Jeong S, Fischer ML.

Environ Sci Technol. 2016 Dec 6;50(23):13123-13133. Epub 2016 Nov 16.

45.

Novel Organic Synthesis through Ultrafast Chemistry.

Wirth T.

Angew Chem Int Ed Engl. 2017 Jan 16;56(3):682-684. doi: 10.1002/anie.201609595. Epub 2016 Nov 28.

PMID:
27891736
46.

Tailored Tumor Immunogenicity Reveals Regulation of CD4 and CD8 T Cell Responses against Cancer.

Knocke S, Fleischmann-Mundt B, Saborowski M, Manns MP, Kühnel F, Wirth TC, Woller N.

Cell Rep. 2016 Nov 22;17(9):2234-2246. doi: 10.1016/j.celrep.2016.10.086.

47.

Stereoselective Ketone Rearrangements with Hypervalent Iodine Reagents.

Malmedy F, Wirth T.

Chemistry. 2016 Nov 2;22(45):16072-16077. doi: 10.1002/chem.201603022. Epub 2016 Aug 19.

PMID:
27539556
48.

The Evolutionary History, Demography, and Spread of the Mycobacterium tuberculosis Complex.

Barbier M, Wirth T.

Microbiol Spectr. 2016 Aug;4(4). doi: 10.1128/microbiolspec.TBTB2-0008-2016. Review.

PMID:
27726798
49.
50.

Contrasting Frustrated Lewis Pair Reactivity with Selenium- and Boron-Based Lewis Acids.

Wilkins LC, Günther BA, Walther M, Lawson JR, Wirth T, Melen RL.

Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11292-5. doi: 10.1002/anie.201605239. Epub 2016 Aug 3.

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