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Items: 1 to 50 of 89

1.

Swiprosin-1/EFhd2 - another piece in the puzzle of tauopathy?

Regensburger M, Mielenz D, Winner B.

Aging (Albany NY). 2018 Apr 25;10(4):522-523. doi: 10.18632/aging.101431. No abstract available.

2.

Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia.

Newton T, Allison R, Edgar JR, Lumb JH, Rodger CE, Manna PT, Rizo T, Kohl Z, Nygren AOH, Arning L, Schüle R, Depienne C, Goldberg L, Frahm C, Stevanin G, Durr A, Schöls L, Winner B, Beetz C, Reid E.

Brain. 2018 May 1;141(5):1286-1299. doi: 10.1093/brain/awy034.

3.

Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis.

Regensburger M, Prots I, Reimer D, Brachs S, Loskarn S, Lie DC, Mielenz D, Winner B.

Stem Cell Reports. 2018 Feb 13;10(2):347-355. doi: 10.1016/j.stemcr.2017.12.010. Epub 2018 Jan 11.

4.

Metabolism of Dopamine in Nucleus Accumbens Astrocytes Is Preserved in Aged Mice Exposed to MPTP.

Winner BM, Zhang H, Farthing MM, Karchalla LM, Lookingland KJ, Goudreau JL.

Front Aging Neurosci. 2017 Dec 12;9:410. doi: 10.3389/fnagi.2017.00410. eCollection 2017.

5.

Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice.

Regensburger M, Schreglmann SR, Stoll S, Rockenstein E, Loskarn S, Xiang W, Masliah E, Winner B.

Brain Struct Funct. 2018 Apr;223(3):1357-1368. doi: 10.1007/s00429-017-1561-5. Epub 2017 Nov 9.

6.

The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases.

Sommer A, Winner B, Prots I.

Mol Neurodegener. 2017 Oct 27;12(1):78. doi: 10.1186/s13024-017-0222-8. Review.

7.

Preoperative Factors That Predict the Need to Morcellate in Total Laparoscopic Hysterectomy.

Wolfe M, Biest S, Tutlam N, Woolfolk C, Winner B.

J Minim Invasive Gynecol. 2018 Jan;25(1):158-162. doi: 10.1016/j.jmig.2017.09.015. Epub 2017 Sep 21.

PMID:
28943192
8.

The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation.

Rothe T, Ipseiz N, Faas M, Lang S, Perez-Branguli F, Metzger D, Ichinose H, Winner B, Schett G, Krönke G.

J Immunol. 2017 May 15;198(10):3878-3885. doi: 10.4049/jimmunol.1600638. Epub 2017 Apr 14.

9.

EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction.

Mielenz D, Reichel M, Jia T, Quinlan EB, Stöckl T, Mettang M, Zilske D, Kirmizi-Alsan E, Schönberger P, Praetner M, Huber SE, Amato D, Schwarz M, Purohit P, Brachs S, Spranger J, Hess A, Büttner C, Ekici AB, Perez-Branguli F, Winner B, Rauschenberger V, Banaschewski T, Bokde ALW, Büchel C, Conrod PJ, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Martinot JL, Lemaitre H, Nees F, Paus T, Smolka MN; IMAGEN Consortium, Schambony A, Bäuerle T, Eulenburg V, Alzheimer C, Lourdusamy A, Schumann G, Müller CP.

Mol Psychiatry. 2018 May;23(5):1303-1319. doi: 10.1038/mp.2017.63. Epub 2017 Apr 11.

PMID:
28397836
10.

Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia.

Allison R, Edgar JR, Pearson G, Rizo T, Newton T, Günther S, Berner F, Hague J, Connell JW, Winkler J, Lippincott-Schwartz J, Beetz C, Winner B, Reid E.

J Cell Biol. 2017 May 1;216(5):1337-1355. doi: 10.1083/jcb.201609033. Epub 2017 Apr 7.

11.

Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress.

Menges S, Minakaki G, Schaefer PM, Meixner H, Prots I, Schlötzer-Schrehardt U, Friedland K, Winner B, Outeiro TF, Winklhofer KF, von Arnim CA, Xiang W, Winkler J, Klucken J.

Sci Rep. 2017 Feb 22;7:42942. doi: 10.1038/srep42942.

12.

Perioperative Outcomes of Total Laparoscopic Hysterectomy With Uncontained Versus Contained Power Morcellation.

Winner B, Porter A, Biest S.

J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S92. doi: 10.1016/j.jmig.2015.08.248. Epub 2015 Oct 15. No abstract available.

PMID:
27679379
13.

The adipokine chemerin amplifies electrical field-stimulated contraction in the isolated rat superior mesenteric artery.

Darios ES, Winner BM, Charvat T, Krasinksi A, Punna S, Watts SW.

Am J Physiol Heart Circ Physiol. 2016 Aug 1;311(2):H498-507. doi: 10.1152/ajpheart.00998.2015. Epub 2016 Jul 1.

14.

Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model.

Sommer A, Fadler T, Dorfmeister E, Hoffmann AC, Xiang W, Winner B, Prots I.

J Neuroinflammation. 2016 Jun 30;13(1):174. doi: 10.1186/s12974-016-0632-5.

15.

Distinct Effects of Chronic Dopaminergic Stimulation on Hippocampal Neurogenesis and Striatal Doublecortin Expression in Adult Mice.

Salvi R, Steigleder T, Schlachetzki JC, Waldmann E, Schwab S, Winner B, Winkler J, Kohl Z.

Front Neurosci. 2016 Mar 11;10:77. doi: 10.3389/fnins.2016.00077. eCollection 2016.

16.

A Lipid Base Formulation for Intramuscular Administration of a Novel Sulfur Donor for Cyanide Antagonism.

Kovacs K, Jayanna PK, Duke A, Winner B, Negrito M, Angalakurthi S, Yu JC, Füredi P, Ludányi K, Sipos P, Rockwood GA, Petrikovics I.

Curr Drug Deliv. 2016;13(8):1351-1357.

PMID:
26996369
17.

Model Testing of PluriTest with Next-Generation Sequencing Data.

Schulze M, Hoja S, Winner B, Winkler J, Edenhofer F, Riemenschneider MJ.

Stem Cells Dev. 2016 Apr 1;25(7):569-71. doi: 10.1089/scd.2015.0266. Epub 2016 Mar 15. No abstract available.

PMID:
26978076
18.

GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient iPSC model.

Mishra HK, Prots I, Havlicek S, Kohl Z, Perez-Branguli F, Boerstler T, Anneser L, Minakaki G, Wend H, Hampl M, Leone M, Brückner M, Klucken J, Reis A, Boyer L, Schuierer G, Behrens J, Lampert A, Engel FB, Gage FH, Winkler J, Winner B.

Ann Neurol. 2016 Mar 11. doi: 10.1002/ana.24633. [Epub ahead of print]

19.

In Reply.

Winner B, Porter A, Biest S.

Obstet Gynecol. 2016 Feb;127(2):403-4. doi: 10.1097/AOG.0000000000001283. No abstract available.

PMID:
26942375
20.

Parenteral dosage form development and testing of dimethyl trisulfide, as an antidote candidate to combat cyanide intoxication.

Kovacs K, Duke AC, Shifflet M, Winner B, Lee SA, Rockwood GA, Petrikovics I.

Pharm Dev Technol. 2017 Dec;22(8):958-963. doi: 10.3109/10837450.2015.1125923. Epub 2016 Jan 7.

PMID:
26740339
21.

Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α-synuclein.

Schlachetzki JC, Grimm T, Schlachetzki Z, Ben Abdallah NM, Ettle B, Vöhringer P, Ferger B, Winner B, Nuber S, Winkler J.

J Neurosci Res. 2016 Jan;94(1):62-73. doi: 10.1002/jnr.23677. Epub 2015 Oct 9.

PMID:
26451750
22.

Uncontained Compared With Contained Power Morcellation in Total Laparoscopic Hysterectomy.

Winner B, Porter A, Velloze S, Biest S.

Obstet Gynecol. 2015 Oct;126(4):834-8. doi: 10.1097/AOG.0000000000001039.

PMID:
26348168
23.

Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors.

Eberhardt E, Havlicek S, Schmidt D, Link AS, Neacsu C, Kohl Z, Hampl M, Kist AM, Klinger A, Nau C, Schüttler J, Alzheimer C, Winkler J, Namer B, Winner B, Lampert A.

Stem Cell Reports. 2015 Sep 8;5(3):305-13. doi: 10.1016/j.stemcr.2015.07.010. Epub 2015 Aug 28.

24.

Kdm6b and Pmepa1 as Targets of Bioelectrically and Behaviorally Induced Activin A Signaling.

Link AS, Kurinna S, Havlicek S, Lehnert S, Reichel M, Kornhuber J, Winner B, Huth T, Zheng F, Werner S, Alzheimer C.

Mol Neurobiol. 2016 Aug;53(6):4210-4225. doi: 10.1007/s12035-015-9363-3. Epub 2015 Jul 28.

PMID:
26215835
25.

Comparison of the structure, function and autophagic maintenance of mitochondria in nigrostriatal and tuberoinfundibular dopamine neurons.

Hawong HY, Patterson JR, Winner BM, Goudreau JL, Lookingland KJ.

Brain Res. 2015 Oct 5;1622:240-51. doi: 10.1016/j.brainres.2015.06.030. Epub 2015 Jul 2.

26.

The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.

Schreglmann SR, Regensburger M, Rockenstein E, Masliah E, Xiang W, Winkler J, Winner B.

PLoS One. 2015 May 11;10(5):e0126261. doi: 10.1371/journal.pone.0126261. eCollection 2015.

27.

Effects of preservation methods of muscle tissue from upper-trophic level reef fishes on stable isotope values (δ (13)C and δ (15)N).

Stallings CD, Nelson JA, Rozar KL, Adams CS, Wall KR, Switzer TS, Winner BL, Hollander DJ.

PeerJ. 2015 Mar 26;3:e874. doi: 10.7717/peerj.874. eCollection 2015.

28.

Adult neurogenesis in neurodegenerative diseases.

Winner B, Winkler J.

Cold Spring Harb Perspect Biol. 2015 Apr 1;7(4):a021287. doi: 10.1101/cshperspect.a021287. Review.

29.

The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.

Purohit P, Perez-Branguli F, Prots I, Borger E, Gunn-Moore F, Welzel O, Loy K, Wenzel EM, Grömer TW, Brachs S, Holzer M, Buslei R, Fritsch K, Regensburger M, Böhm KJ, Winner B, Mielenz D.

PLoS One. 2014 Aug 18;9(8):e103976. doi: 10.1371/journal.pone.0103976. eCollection 2014.

30.

Adult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticity.

Regensburger M, Prots I, Winner B.

Neural Plast. 2014;2014:454696. doi: 10.1155/2014/454696. Epub 2014 Jul 3. Review.

31.

Thoracic rat spinal cord contusion injury induces remote spinal gliogenesis but not neurogenesis or gliogenesis in the brain.

Franz S, Ciatipis M, Pfeifer K, Kierdorf B, Sandner B, Bogdahn U, Blesch A, Winner B, Weidner N.

PLoS One. 2014 Jul 22;9(7):e102896. doi: 10.1371/journal.pone.0102896. eCollection 2014.

32.

Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells.

Ettle B, Reiprich S, Deusser J, Schlachetzki JC, Xiang W, Prots I, Masliah E, Winner B, Wegner M, Winkler J.

Mol Cell Neurosci. 2014 Sep;62:68-78. doi: 10.1016/j.mcn.2014.06.012. Epub 2014 Jul 11.

33.

The physical activity energy cost of the latest active video games in young adults.

Howe CA, Barr MW, Winner BC, Kimble JR, White JB.

J Phys Act Health. 2015 Feb;12(2):171-7. doi: 10.1123/jpah.2013-0023. Epub 2014 Jun 5.

PMID:
24905451
34.

Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease.

Winner B, Marchetto MC, Winkler J, Gage FH.

Hum Mol Genet. 2014 Sep 15;23(R1):R27-34. doi: 10.1093/hmg/ddu205. Epub 2014 May 12. Review.

PMID:
24821704
35.

Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia.

Pérez-Brangulí F, Mishra HK, Prots I, Havlicek S, Kohl Z, Saul D, Rummel C, Dorca-Arevalo J, Regensburger M, Graef D, Sock E, Blasi J, Groemer TW, Schlötzer-Schrehardt U, Winkler J, Winner B.

Hum Mol Genet. 2014 Sep 15;23(18):4859-74. doi: 10.1093/hmg/ddu200. Epub 2014 May 2.

36.

α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy.

May VE, Ettle B, Poehler AM, Nuber S, Ubhi K, Rockenstein E, Winner B, Wegner M, Masliah E, Winkler J.

Neurobiol Aging. 2014 Oct;35(10):2357-68. doi: 10.1016/j.neurobiolaging.2014.02.028. Epub 2014 Mar 4.

37.

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.

Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Trejo-Morales M, Gerez J, Picotti P, Jensen PH, Campioni S, Riek R, Winkler J, Gage FH, Winner B, Masliah E.

Brain. 2014 May;137(Pt 5):1496-513. doi: 10.1093/brain/awu057. Epub 2014 Mar 24.

38.

Increased tyrosine hydroxylase expression accompanied by glial changes within the non-lesioned hemisphere in the 6-hydroxydopamine model of Parkinson's disease.

Schlachetzki JC, Marxreiter F, Regensburger M, Kulinich A, Winner B, Winkler J.

Restor Neurol Neurosci. 2014;32(4):447-62. doi: 10.3233/RNN-130371.

PMID:
24604006
39.

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons.

Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, Schlötzer-Schrehardt U, Winkler J, Gage FH, Winner B.

Hum Mol Genet. 2014 May 15;23(10):2527-41. doi: 10.1093/hmg/ddt644. Epub 2013 Dec 30.

40.

Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice.

Marxreiter F, Ettle B, May VE, Esmer H, Patrick C, Kragh CL, Klucken J, Winner B, Riess O, Winkler J, Masliah E, Nuber S.

Neurobiol Dis. 2013 Nov;59:38-51. doi: 10.1016/j.nbd.2013.07.004. Epub 2013 Jul 16.

41.

α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

Prots I, Veber V, Brey S, Campioni S, Buder K, Riek R, Böhm KJ, Winner B.

J Biol Chem. 2013 Jul 26;288(30):21742-54. doi: 10.1074/jbc.M113.451815. Epub 2013 Jun 6.

42.

Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus.

Winner B, Regensburger M, Schreglmann S, Boyer L, Prots I, Rockenstein E, Mante M, Zhao C, Winkler J, Masliah E, Gage FH.

J Neurosci. 2012 Nov 21;32(47):16906-16. doi: 10.1523/JNEUROSCI.2723-12.2012.

43.

α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1.

Desplats P, Spencer B, Crews L, Pathel P, Morvinski-Friedmann D, Kosberg K, Roberts S, Patrick C, Winner B, Winkler J, Masliah E.

J Biol Chem. 2012 Sep 14;287(38):31691-702. doi: 10.1074/jbc.M112.354522. Epub 2012 Jul 25.

44.

Impaired olfactory bulb neurogenesis depends on the presence of human wild-type alpha-synuclein.

May VE, Nuber S, Marxreiter F, Riess O, Winner B, Winkler J.

Neuroscience. 2012 Oct 11;222:343-55. doi: 10.1016/j.neuroscience.2012.07.001. Epub 2012 Jul 17.

PMID:
22814000
45.

LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors.

Hinkle KM, Yue M, Behrouz B, Dächsel JC, Lincoln SJ, Bowles EE, Beevers JE, Dugger B, Winner B, Prots I, Kent CB, Nishioka K, Lin WL, Dickson DW, Janus CJ, Farrer MJ, Melrose HL.

Mol Neurodegener. 2012 May 30;7:25. doi: 10.1186/1750-1326-7-25.

46.

Effectiveness of long-acting reversible contraception.

Winner B, Peipert JF, Zhao Q, Buckel C, Madden T, Allsworth JE, Secura GM.

N Engl J Med. 2012 May 24;366(21):1998-2007. doi: 10.1056/NEJMoa1110855.

47.

Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis.

Bracko O, Singer T, Aigner S, Knobloch M, Winner B, Ray J, Clemenson GD Jr, Suh H, Couillard-Despres S, Aigner L, Gage FH, Jessberger S.

J Neurosci. 2012 Mar 7;32(10):3376-87. doi: 10.1523/JNEUROSCI.4248-11.2012.

48.

Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model.

Kohl Z, Winner B, Ubhi K, Rockenstein E, Mante M, Münch M, Barlow C, Carter T, Masliah E, Winkler J.

Eur J Neurosci. 2012 Jan;35(1):10-9. doi: 10.1111/j.1460-9568.2011.07933.x.

49.

Neurodegenerative disease and adult neurogenesis.

Winner B, Kohl Z, Gage FH.

Eur J Neurosci. 2011 Mar;33(6):1139-51. doi: 10.1111/j.1460-9568.2011.07613.x. Review.

PMID:
21395858
50.

In vivo demonstration that alpha-synuclein oligomers are toxic.

Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, Pham E, Masliah E, Gage FH, Riek R.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4194-9. doi: 10.1073/pnas.1100976108. Epub 2011 Feb 15.

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