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Items: 1 to 50 of 206

1.

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia.

Carvajal LA, Neriah DB, Senecal A, Benard L, Thiruthuvanathan V, Yatsenko T, Narayanagari SR, Wheat JC, Todorova TI, Mitchell K, Kenworthy C, Guerlavais V, Annis DA, Bartholdy B, Will B, Anampa JD, Mantzaris I, Aivado M, Singer RH, Coleman RA, Verma A, Steidl U.

Sci Transl Med. 2018 Apr 11;10(436). pii: eaao3003. doi: 10.1126/scitranslmed.aao3003.

PMID:
29643228
2.

Gingival ulceration in a 63-year-old lung transplant recipient.

Will BM, Peters SM, Eisig SB, Grbic JT, McKenzie MA, Yoon AJ, Philipone EM.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Feb 8. pii: S2212-4403(18)30068-3. doi: 10.1016/j.oooo.2018.02.001. [Epub ahead of print] No abstract available.

PMID:
29545078
3.

LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML.

Cusan M, Cai SF, Mohammad HP, Krivtsov A, Chramiec A, Loizou E, Witkin MD, Smitheman KN, Tenen DG, Ye M, Will B, Steidl U, Kruger RG, Levine RL, Rienhoff HY Jr, Koche RP, Armstrong SA.

Blood. 2018 Apr 12;131(15):1730-1742. doi: 10.1182/blood-2017-09-807024. Epub 2018 Feb 16.

PMID:
29453291
4.

The Cost-Effectiveness of Lowering Permissible Noise Levels Around U.S. Airports.

Jiao B, Zafari Z, Will B, Ruggeri K, Li S, Muennig P.

Int J Environ Res Public Health. 2017 Dec 2;14(12). pii: E1497. doi: 10.3390/ijerph14121497.

5.

Pharmacological inhibition of the transcription factor PU.1 in leukemia.

Antony-Debré I, Paul A, Leite J, Mitchell K, Kim HM, Carvajal LA, Todorova TI, Huang K, Kumar A, Farahat AA, Bartholdy B, Narayanagari SR, Chen J, Ambesi-Impiombato A, Ferrando AA, Mantzaris I, Gavathiotis E, Verma A, Will B, Boykin DW, Wilson WD, Poon GM, Steidl U.

J Clin Invest. 2017 Dec 1;127(12):4297-4313. doi: 10.1172/JCI92504. Epub 2017 Oct 30.

6.

Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation.

Bhagat TD, Chen S, Bartenstein M, Barlowe AT, Von Ahrens D, Choudhary GS, Tivnan P, Amin E, Marcondes AM, Sanders MA, Hoogenboezem RM, Kambhampati S, Ramachandra N, Mantzaris I, Sukrithan V, Laurence R, Lopez R, Bhagat P, Giricz O, Sohal D, Wickrema A, Yeung C, Gritsman K, Aplan P, Hochedlinger K, Yu Y, Pradhan K, Zhang J, Greally JM, Mukherjee S, Pellagatti A, Boultwood J, Will B, Steidl U, Raaijmakers MHGP, Deeg HJ, Kharas MG, Verma A.

Cancer Res. 2017 Sep 15;77(18):4846-4857. doi: 10.1158/0008-5472.CAN-17-0282. Epub 2017 Jul 6.

PMID:
28684528
7.

Identification of allergens by IgE-specific testing improves outcomes in atopic dermatitis.

Will BM, Severino R, Johnson DW.

Int J Dermatol. 2017 Nov;56(11):1150-1153. doi: 10.1111/ijd.13673. Epub 2017 Jun 20.

PMID:
28631812
8.

The Application of CRISPR/Cas Technology to Efficiently Model Complex Cancer Genomes in Stem Cells.

Albitar A, Rohani B, Will B, Yan A, Gallicano GI.

J Cell Biochem. 2018 Jan;119(1):134-140. doi: 10.1002/jcb.26195. Epub 2017 Jul 11.

PMID:
28594094
9.

A myeloid tumor suppressor role for NOL3.

Stanley RF, Piszczatowski RT, Bartholdy B, Mitchell K, McKimpson WM, Narayanagari S, Walter D, Todorova TI, Hirsch C, Makishima H, Will B, McMahon C, Gritsman K, Maciejewski JP, Kitsis RN, Steidl U.

J Exp Med. 2017 Mar 6;214(3):753-771. doi: 10.1084/jem.20162089. Epub 2017 Feb 23.

10.

Stem and progenitor cell alterations in myelodysplastic syndromes.

Shastri A, Will B, Steidl U, Verma A.

Blood. 2017 Mar 23;129(12):1586-1594. doi: 10.1182/blood-2016-10-696062. Epub 2017 Feb 3. Review.

11.

Leukemic Stem Cells S(p)liced Off.

Ferreira-Teixeira M, Will B.

Cell Stem Cell. 2016 Nov 3;19(5):561-563. doi: 10.1016/j.stem.2016.10.016.

12.

Parental perception of treatment and medical care in children with craniosynostosis.

Kluba S, Rohleder S, Wolff M, Haas-Lude K, Schuhmann MU, Will BE, Reinert S, Krimmel M.

Int J Oral Maxillofac Surg. 2016 Nov;45(11):1341-1346. doi: 10.1016/j.ijom.2016.03.017. Epub 2016 Apr 23.

PMID:
27117394
13.

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.

Pietras EM, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang S, Lakshminarasimhan R, Chin CP, Techner JM, Will B, Nerlov C, Steidl U, Manz MG, Schroeder T, Passegué E.

Nat Cell Biol. 2016 Jun;18(6):607-18. doi: 10.1038/ncb3346. Epub 2016 Apr 25.

14.

Thrombocytopenia in MDS: epidemiology, mechanisms, clinical consequences and novel therapeutic strategies.

Li W, Morrone K, Kambhampati S, Will B, Steidl U, Verma A.

Leukemia. 2016 Mar;30(3):536-44. doi: 10.1038/leu.2015.297. Epub 2015 Oct 26. Review.

PMID:
26500138
15.

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.

Okoye-Okafor UC, Bartholdy B, Cartier J, Gao EN, Pietrak B, Rendina AR, Rominger C, Quinn C, Smallwood A, Wiggall KJ, Reif AJ, Schmidt SJ, Qi H, Zhao H, Joberty G, Faelth-Savitski M, Bantscheff M, Drewes G, Duraiswami C, Brady P, Groy A, Narayanagari SR, Antony-Debre I, Mitchell K, Wang HR, Kao YR, Christopeit M, Carvajal L, Barreyro L, Paietta E, Makishima H, Will B, Concha N, Adams ND, Schwartz B, McCabe MT, Maciejewski J, Verma A, Steidl U.

Nat Chem Biol. 2015 Nov;11(11):878-86. doi: 10.1038/nchembio.1930. Epub 2015 Oct 5.

16.

Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia.

Will B, Vogler TO, Narayanagari S, Bartholdy B, Todorova TI, da Silva Ferreira M, Chen J, Yu Y, Mayer J, Barreyro L, Carvajal L, Neriah DB, Roth M, van Oers J, Schaetzlein S, McMahon C, Edelmann W, Verma A, Steidl U.

Nat Med. 2015 Oct;21(10):1172-81. doi: 10.1038/nm.3936. Epub 2015 Sep 7.

17.

A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation.

Sun J, Bonaguidi MA, Jun H, Guo JU, Sun GJ, Will B, Yang Z, Jang MH, Song H, Ming GL, Christian KM.

Mol Brain. 2015 Sep 4;8:52. doi: 10.1186/s13041-015-0143-9.

18.

IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells.

Schinke C, Giricz O, Li W, Shastri A, Gordon S, Barreyro L, Bhagat T, Bhattacharyya S, Ramachandra N, Bartenstein M, Pellagatti A, Boultwood J, Wickrema A, Yu Y, Will B, Wei S, Steidl U, Verma A.

Blood. 2015 May 14;125(20):3144-52. doi: 10.1182/blood-2015-01-621631. Epub 2015 Mar 25. Erratum in: Blood. 2015 Jul 16;126(3):425. Barreryo, Laura [corrected to Barreyro, Laura].

19.

Bloody signals: from birth to disease and death.

Trompouki E, King KY, Will B, Lessard J, Flores-Figueroa E, Kokkaliaris KD, Bowman T.

Exp Hematol. 2014 Dec;42(12):989-94. doi: 10.1016/j.exphem.2014.10.007. No abstract available.

PMID:
25482344
20.

Combinatorial haplo-deficient tumor suppression in 7q-deficient myelodysplastic syndrome and acute myeloid leukemia.

Will B, Steidl U.

Cancer Cell. 2014 May 12;25(5):555-7. doi: 10.1016/j.ccr.2014.04.018. Erratum in: Cancer Cell. 2014 Jun 16;25(6):860.

21.

Eltrombopag can overcome the anti-megakaryopoietic effects of lenalidomide without increasing proliferation of the malignant myelodysplastic syndrome/acute myelogenous leukemia clone.

Tamari R, Schinke C, Bhagat T, Roth M, Braunschweig I, Will B, Steidl U, Verma A.

Leuk Lymphoma. 2014 Dec;55(12):2901-6. doi: 10.3109/10428194.2014.894186. Epub 2014 Mar 20.

PMID:
24650011
22.

Stem cell fate regulation by dynein motor protein Lis1.

Will B, Steidl U.

Nat Genet. 2014 Mar;46(3):217-8. doi: 10.1038/ng.2902.

PMID:
24569235
23.

HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia.

Bartholdy B, Christopeit M, Will B, Mo Y, Barreyro L, Yu Y, Bhagat TD, Okoye-Okafor UC, Todorova TI, Greally JM, Levine RL, Melnick A, Verma A, Steidl U.

J Clin Invest. 2014 Mar;124(3):1158-67.

24.

Stem cell origin of myelodysplastic syndromes.

Elias HK, Schinke C, Bhattacharyya S, Will B, Verma A, Steidl U.

Oncogene. 2014 Oct 30;33(44):5139-50. doi: 10.1038/onc.2013.520. Epub 2013 Dec 16. Review.

PMID:
24336326
25.

Clinical and imaging findings in children with non-syndromic lambdoid synostosis.

Haas-Lude K, Wolff M, Will B, Bender B, Krimmel M.

Eur J Pediatr. 2014 Apr;173(4):435-40. doi: 10.1007/s00431-013-2186-1. Epub 2013 Oct 27.

PMID:
24162514
26.

Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.

Will B, Vogler TO, Bartholdy B, Garrett-Bakelman F, Mayer J, Barreyro L, Pandolfi A, Todorova TI, Okoye-Okafor UC, Stanley RF, Bhagat TD, Verma A, Figueroa ME, Melnick A, Roth M, Steidl U.

Nat Immunol. 2013 May;14(5):437-45. doi: 10.1038/ni.2572. Epub 2013 Apr 7.

27.

[Competency-based medical education: National Catalogue of Learning Objectives in surgery].

Kadmon M, Bender MJ, Adili F, Arbab D, Heinemann MK, Hofmann HS, König S, Küper MA, Obertacke U, Rennekampff HO, Rolle U, Rücker M, Sader R, Tingart M, Tolksdorf MM, Tronnier V, Will B, Walcher F; für die Chirurgische Arbeitsgemeinschaft Lehre der Deutschen Gesellschaft für Chirurgie (CAL).

Chirurg. 2013 Apr;84(4):277-85. doi: 10.1007/s00104-012-2449-9. German.

PMID:
23494054
28.

Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms.

Nischal S, Bhattacharyya S, Christopeit M, Yu Y, Zhou L, Bhagat TD, Sohal D, Will B, Mo Y, Suzuki M, Pardanani A, McDevitt M, Maciejewski JP, Melnick AM, Greally JM, Steidl U, Moliterno A, Verma A.

Cancer Res. 2013 Feb 1;73(3):1076-85. doi: 10.1158/0008-5472.CAN-12-0735. Epub 2012 Oct 11.

29.

H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia.

Kawahara M, Pandolfi A, Bartholdy B, Barreyro L, Will B, Roth M, Okoye-Okafor UC, Todorova TI, Figueroa ME, Melnick A, Mitsiades CS, Steidl U.

Cancer Cell. 2012 Aug 14;22(2):194-208. doi: 10.1016/j.ccr.2012.06.027.

30.

Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα.

Radomska HS, Alberich-Jordà M, Will B, Gonzalez D, Delwel R, Tenen DG.

J Clin Invest. 2012 Aug;122(8):2955-66. doi: 10.1172/JCI43354. Epub 2012 Jul 17.

31.

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.

Will B, Zhou L, Vogler TO, Ben-Neriah S, Schinke C, Tamari R, Yu Y, Bhagat TD, Bhattacharyya S, Barreyro L, Heuck C, Mo Y, Parekh S, McMahon C, Pellagatti A, Boultwood J, Montagna C, Silverman L, Maciejewski J, Greally JM, Ye BH, List AF, Steidl C, Steidl U, Verma A.

Blood. 2012 Sep 6;120(10):2076-86. doi: 10.1182/blood-2011-12-399683. Epub 2012 Jul 2.

32.

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS.

Barreyro L, Will B, Bartholdy B, Zhou L, Todorova TI, Stanley RF, Ben-Neriah S, Montagna C, Parekh S, Pellagatti A, Boultwood J, Paietta E, Ketterling RP, Cripe L, Fernandez HF, Greenberg PL, Tallman MS, Steidl C, Mitsiades CS, Verma A, Steidl U.

Blood. 2012 Aug 9;120(6):1290-8. doi: 10.1182/blood-2012-01-404699. Epub 2012 Jun 21.

33.

Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation.

Roth M, Will B, Simkin G, Narayanagari S, Barreyro L, Bartholdy B, Tamari R, Mitsiades CS, Verma A, Steidl U.

Blood. 2012 Jul 12;120(2):386-94. doi: 10.1182/blood-2011-12-399667. Epub 2012 May 24.

34.

Value of high-resolution ultrasound in the differential diagnosis of scaphocephaly and occipital plagiocephaly.

Krimmel M, Will B, Wolff M, Kluba S, Haas-Lude K, Schaefer J, Schuhmann MU, Reinert S.

Int J Oral Maxillofac Surg. 2012 Jul;41(7):797-800. doi: 10.1016/j.ijom.2012.02.022. Epub 2012 Apr 15.

PMID:
22510342
35.

Lack of correlation of overnight monitoring data and lumbar infusion data in iNPH patients.

Speil A, Sosa JC, Will BE, Schuhmann MU.

Acta Neurochir Suppl. 2012;114:213-6. doi: 10.1007/978-3-7091-0956-4_41.

PMID:
22327695
36.

Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus.

Volpi SA, Verma-Gaur J, Hassan R, Ju Z, Roa S, Chatterjee S, Werling U, Hou H Jr, Will B, Steidl U, Scharff M, Edelman W, Feeney AJ, Birshtein BK.

J Immunol. 2012 Mar 15;188(6):2556-66. doi: 10.4049/jimmunol.1102763. Epub 2012 Feb 17.

37.

[Psychosocial integration of inpatients with borderline personality disorder: reflection of a health care system focused on symptom remission].

Gescher DM, Will B, Malevani J.

Nervenarzt. 2013 Mar;84(3):326-33. doi: 10.1007/s00115-011-3462-9. German.

PMID:
22318361
38.

The effect of vasospasm on cerebral perfusion: a colour duplex study of the extra- and intracranial cerebral arteries.

Schöning M, Scheel P, Wittibschläger J, Kehrer M, Will BE.

Ultrasound Med Biol. 2012 Mar;38(3):360-7. doi: 10.1016/j.ultrasmedbio.2011.12.013. Epub 2012 Jan 21.

PMID:
22266230
39.

A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2.

Kaufmann KB, Gründer A, Hadlich T, Wehrle J, Gothwal M, Bogeska R, Seeger TS, Kayser S, Pham KB, Jutzi JS, Ganzenmüller L, Steinemann D, Schlegelberger B, Wagner JM, Jung M, Will B, Steidl U, Aumann K, Werner M, Günther T, Schüle R, Rambaldi A, Pahl HL.

J Exp Med. 2012 Jan 16;209(1):35-50. doi: 10.1084/jem.20110540. Epub 2012 Jan 9.

40.

[Neonatal intracerebral bleeding as initial symptom of gliomatosis cerebri WHO III--neurological outcome after partial hemispherectomy].

Wacker-Gussmann A, Neunhoeffer F, Alber M, Scheel-Walter HG, Schittenhelm J, Will BE.

Z Geburtshilfe Neonatol. 2011 Oct;215(5):212-5. doi: 10.1055/s-0031-1277173. Epub 2011 Oct 25. German.

PMID:
22028063
41.

A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.

Wontakal SN, Guo X, Will B, Shi M, Raha D, Mahajan MC, Weissman S, Snyder M, Steidl U, Zheng D, Skoultchi AI.

PLoS Genet. 2011 Jun;7(6):e1001392. doi: 10.1371/journal.pgen.1001392. Epub 2011 Jun 9.

42.

Multi-parameter fluorescence-activated cell sorting and analysis of stem and progenitor cells in myeloid malignancies.

Will B, Steidl U.

Best Pract Res Clin Haematol. 2010 Sep;23(3):391-401. doi: 10.1016/j.beha.2010.06.006. Review.

43.

Neuronal cell death during metamorphosis of Hydractina echinata (Cnidaria, Hydrozoa).

Seipp S, Schmich J, Will B, Schetter E, Plickert G, Leitz T.

Invert Neurosci. 2010 Dec;10(2):77-91. doi: 10.1007/s10158-010-0109-7. Epub 2010 Nov 23.

PMID:
21104287
44.

Predictive factors for neurocognitive function and Quality of Life after surgical treatment for Cushing's disease and acromegaly.

Psaras T, Milian M, Hattermann V, Will BE, Tatagiba M, Honegger J.

J Endocrinol Invest. 2011 Jul-Aug;34(7):e168-77. doi: 10.3275/7333. Epub 2010 Nov 8.

PMID:
21060251
45.

[A topodiagnostically characteristic visual field defect].

Bruckmann A, Lüke J, Will BE, Schiefer U.

Ophthalmologe. 2010 Dec;107(12):1164-8. doi: 10.1007/s00347-010-2229-1. German.

PMID:
20922531
46.

Variant CJD: where has it gone, or has it?

Will B.

Pract Neurol. 2010 Oct;10(5):250-1. doi: 10.1136/jnnp.2010.223693. No abstract available.

PMID:
20858625
47.

An organizing region in metamorphosing hydrozoan planula larvae--stimulation of axis formation in both larval and in adult tissue.

Stumpf M, Will B, Wittig K, Kasper J, Fischer B, Schmich J, Seipp S, Leitz T.

Int J Dev Biol. 2010;54(5):795-802. doi: 10.1387/ijdb.082738ms.

48.

Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells.

Will B, Siddiqi T, Jordà MA, Shimamura T, Luptakova K, Staber PB, Costa DB, Steidl U, Tenen DG, Kobayashi S.

Blood. 2010 Apr 8;115(14):2901-9. doi: 10.1182/blood-2009-03-209544. Epub 2010 Feb 16.

49.

Surgical technique and validation of outcome assessment in sagittal synostosis.

Psaras T, Schuhmann MU, Bottler T, Krimmel M, Wolff M, Honegger JB, Will BE.

Cent Eur Neurosurg. 2010 May;71(2):64-8. doi: 10.1055/s-0029-1220714. Epub 2010 Jan 13.

PMID:
20072989
50.

Evaluation of quality of life parameters in patients who have syringomyelia.

Sixt C, Riether F, Will BE, Tatagiba MS, Roser F.

J Clin Neurosci. 2009 Dec;16(12):1599-603. doi: 10.1016/j.jocn.2009.04.019. Epub 2009 Oct 8.

PMID:
19818628

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