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Items: 39

1.

A First-in-Human, Phase I, Dose-Escalation Study of TAK-117, a Selective PI3Kα Isoform Inhibitor, in Patients with Advanced Solid Malignancies.

Juric D, de Bono JS, LoRusso PM, Nemunaitis J, Heath EI, Kwak EL, Macarulla Mercadé T, Geuna E, Jose de Miguel-Luken M, Patel C, Kuida K, Sankoh S, Westin EH, Zohren F, Shou Y, Tabernero J.

Clin Cancer Res. 2017 Sep 1;23(17):5015-5023. doi: 10.1158/1078-0432.CCR-16-2888. Epub 2017 May 10.

PMID:
28490463
2.

Two Phase 1 dose-escalation studies exploring multiple regimens of litronesib (LY2523355), an Eg5 inhibitor, in patients with advanced cancer.

Infante JR, Patnaik A, Verschraegen CF, Olszanski AJ, Shaheen M, Burris HA, Tolcher AW, Papadopoulos KP, Beeram M, Hynes SM, Leohr J, Lin AB, Li LQ, McGlothlin A, Farrington DL, Westin EH, Cohen RB.

Cancer Chemother Pharmacol. 2017 Feb;79(2):315-326. doi: 10.1007/s00280-016-3205-5. Epub 2017 Jan 17.

PMID:
28097385
3.

A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer Cells and Shows Potent Antitumor Activity in Xenograft Tumor Models.

Ye XS, Fan L, Van Horn RD, Nakai R, Ohta Y, Akinaga S, Murakata C, Yamashita Y, Yin T, Credille KM, Donoho GP, Merzoug FF, Li H, Aggarwal A, Blanchard K, Westin EH.

Mol Cancer Ther. 2015 Nov;14(11):2463-72. doi: 10.1158/1535-7163.MCT-15-0241. Epub 2015 Aug 24.

4.

Lymphoma and myeloma in older patients.

Westin EH, Longo DL.

Semin Oncol. 2004 Apr;31(2):198-205. Review.

PMID:
15112150
5.

T-small cell disorders.

Westin EH, Longo DL.

Curr Treat Options Oncol. 2001 Jun;2(3):225-35. Review.

PMID:
12057122
6.

Estrogen receptor expression and function in long-term estrogen-deprived human breast cancer cells.

Jeng MH, Shupnik MA, Bender TP, Westin EH, Bandyopadhyay D, Kumar R, Masamura S, Santen RJ.

Endocrinology. 1998 Oct;139(10):4164-74.

PMID:
9751496
7.

Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and actin filament integrity.

Qian Y, Baisden JM, Westin EH, Guappone AC, Koay TC, Flynn DC.

Oncogene. 1998 Apr 30;16(17):2185-95.

8.
9.
10.

Characterization of a rearrangement in the c-MYB promoter in the acute lymphoblastic leukemia cell line CCRF-CEM.

Jacobs SM, Gorse KM, Kennedy SJ, Westin EH.

Cancer Genet Cytogenet. 1994 Jul 1;75(1):31-9.

PMID:
8039161
11.

Role for the stem cell factor/KIT complex in Schwann cell neoplasia and mast cell proliferation associated with neurofibromatosis.

Ryan JJ, Klein KA, Neuberger TJ, Leftwich JA, Westin EH, Kauma S, Fletcher JA, DeVries GH, Huff TF.

J Neurosci Res. 1994 Feb 15;37(3):415-32.

PMID:
7513766
13.

Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells.

Brigle KE, Spinella MJ, Westin EH, Goldman ID.

Biochem Pharmacol. 1994 Jan 20;47(2):337-45.

PMID:
8304978
14.

Identification of a second promoter in the human c-myb proto-oncogene.

Jacobs SM, Gorse KM, Westin EH.

Oncogene. 1994 Jan;9(1):227-35.

PMID:
8302584
16.

Multiple mechanisms of regulation of the human c-myb gene during myelomonocytic differentiation.

Boise LH, Gorse KM, Westin EH.

Oncogene. 1992 Sep;7(9):1817-25.

PMID:
1323820
18.
19.
21.
22.

Differentiation of mouse erythroleukemia cells enhanced by alternatively spliced c-myb mRNA.

Weber BL, Westin EH, Clarke MF.

Science. 1990 Sep 14;249(4974):1291-3.

PMID:
2205003
23.

Alternative splicing of the human c-myb gene.

Westin EH, Gorse KM, Clarke MF.

Oncogene. 1990 Aug;5(8):1117-24.

PMID:
2202948
24.

Cloning and characterization of complementary DNA for human tryptase.

Miller JS, Westin EH, Schwartz LB.

J Clin Invest. 1989 Oct;84(4):1188-95.

25.

Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier.

Schuetz JD, Westin EH, Matherly LH, Pincus R, Swerdlow PS, Goldman ID.

J Biol Chem. 1989 Sep 25;264(27):16261-7.

26.

Severe reaction to vancomycin not mediated by histamine release and documented by rechallenge.

Sahai JV, Polk RE, Schwartz LB, Healy DP, Westin EH.

J Infect Dis. 1988 Dec;158(6):1413-4. No abstract available.

PMID:
2461997
27.

Use of phorbol-12,13-dibutyrate as a mitogen in the cytogenetic analysis of tumors with low mitotic indexes.

Eiseman E, Luck JB, Mills AS, Brown JA, Westin EH.

Cancer Genet Cytogenet. 1988 Sep;34(2):165-75.

PMID:
3136909
28.
29.

Establishing paternity using minisatellite DNA probes when the putative father is unavailable for testing.

Odelberg SJ, Demers DB, Westin EH, Hossaini AA.

J Forensic Sci. 1988 Jul;33(4):921-8.

PMID:
2902188
31.

Altered regulation of c-myc in an HL-60 differentiation resistant subclone, HL-60-1E3.

Ely CM, Leftwich JA, Chenevix-Trench G, Hall RE, Westin EH.

Cancer Res. 1987 Sep 1;47(17):4595-600.

32.

Cytogenetic and molecular genetic studies of a patient with atypical lymphoid hyperplasia.

Chenevix-Trench G, Cowan JM, Behm FG, Goorha R, Brown JA, Westin EH, Francke U.

Cancer Genet Cytogenet. 1987 Aug;27(2):251-9.

PMID:
3036340
33.

Somatic rearrangement of the c-myc oncogene in primary human diffuse large-cell lymphoma.

Chenevix-Trench G, Behm FG, Westin EH.

Int J Cancer. 1986 Oct 15;38(4):513-6.

PMID:
3019898
34.

NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice.

Thorgeirsson UP, Turpeenniemi-Hujanen T, Williams JE, Westin EH, Heilman CA, Talmadge JE, Liotta LA.

Mol Cell Biol. 1985 Jan;5(1):259-62.

35.

Transforming potential of human c-sis nucleotide sequences encoding platelet-derived growth factor.

Josephs SF, Ratner L, Clarke MF, Westin EH, Reitz MS, Wong-Staal F.

Science. 1984 Aug 10;225(4662):636-9.

PMID:
6740330
36.

Lack of expression of cellular homologues of retroviral onc genes in bovine tumors.

Kettmann R, Westin EH, Marbaix G, Deschamps J, Wong-Staal F, Gallo RC, Burny A.

Haematol Blood Transfus. 1983;28:218-21. No abstract available.

PMID:
6305790
37.

Differential expression of the amv gene in human hematopoietic cells.

Westin EH, Gallo RC, Arya SK, Eva A, Souza LM, Baluda MA, Aaronson SA, Wong-Staal F.

Proc Natl Acad Sci U S A. 1982 Apr;79(7):2194-8.

38.

Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.

Westin EH, Wong-Staal F, Gelmann EP, Dalla-Favera R, Papas TS, Lautenberger JA, Eva A, Reddy EP, Tronick SR, Aaronson SA, Gallo RC.

Proc Natl Acad Sci U S A. 1982 Apr;79(8):2490-4.

39.

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.

Eva A, Robbins KC, Andersen PR, Srinivasan A, Tronick SR, Reddy EP, Ellmore NW, Galen AT, Lautenberger JA, Papas TS, Westin EH, Wong-Staal F, Gallo RC, Aaronson SA.

Nature. 1982 Jan 14;295(5845):116-9.

PMID:
6173755

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