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Items: 11

1.

PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production.

Werder RB, Lynch JP, Simpson JC, Zhang V, Hodge NH, Poh M, Forbes-Blom E, Kulis C, Smythe ML, Upham JW, Spann K, Everard ML, Phipps S.

Sci Transl Med. 2018 May 9;10(440). pii: eaao0052. doi: 10.1126/scitranslmed.aao0052.

PMID:
29743346
2.

Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion.

Lynch JP, Werder RB, Loh Z, Sikder MAA, Curren B, Zhang V, Rogers MJ, Lane K, Simpson J, Mazzone SB, Spann K, Hayball J, Diener K, Everard ML, Blyth CC, Forstner C, Dennis PG, Murtaza N, Morrison M, Ó Cuív P, Zhang P, Haque A, Hill GR, Sly PD, Upham JW, Phipps S.

J Exp Med. 2018 Feb 5;215(2):537-557. doi: 10.1084/jem.20170298. Epub 2017 Dec 22.

PMID:
29273643
3.

Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity.

Werder RB, Zhang V, Lynch JP, Snape N, Upham JW, Spann K, Phipps S.

J Allergy Clin Immunol. 2018 May;141(5):1607-1619.e9. doi: 10.1016/j.jaci.2017.07.051. Epub 2017 Sep 22.

PMID:
28947081
4.

Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation.

Al-Kouba J, Wilkinson AN, Starkey MR, Rudraraju R, Werder RB, Liu X, Law SC, Horvat JC, Brooks JF, Hill GR, Davies JM, Phipps S, Hansbro PM, Steptoe RJ.

JCI Insight. 2017 Jun 2;2(11). pii: 85742. doi: 10.1172/jci.insight.85742. [Epub ahead of print]

5.

The Absence of Interferon-β Promotor Stimulator-1 (IPS-1) Predisposes to Bronchiolitis and Asthma-like Pathology in Response to Pneumoviral Infection in Mice.

Simpson J, Lynch JP, Loh Z, Zhang V, Werder RB, Spann K, Phipps S.

Sci Rep. 2017 May 24;7(1):2353. doi: 10.1038/s41598-017-02564-9.

6.

The Influence of the Microbiome on Early-Life Severe Viral Lower Respiratory Infections and Asthma-Food for Thought?

Lynch JP, Sikder MA, Curren BF, Werder RB, Simpson J, Cuív PÓ, Dennis PG, Everard ML, Phipps S.

Front Immunol. 2017 Feb 16;8:156. doi: 10.3389/fimmu.2017.00156. eCollection 2017. Review.

7.

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma.

Arikkatt J, Ullah MA, Short KR, Zhang V, Gan WJ, Loh Z, Werder RB, Simpson J, Sly PD, Mazzone SB, Spann KM, Ferreira MA, Upham JW, Sukkar MB, Phipps S.

Elife. 2017 Jan 18;6. pii: e21199. doi: 10.7554/eLife.21199.

8.

Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling.

Ferreira MA, Jansen R, Willemsen G, Penninx B, Bain LM, Vicente CT, Revez JA, Matheson MC, Hui J, Tung JY, Baltic S, Le Souëf P, Montgomery GW, Martin NG, Robertson CF, James A, Thompson PJ, Boomsma DI, Hopper JL, Hinds DA, Werder RB, Phipps S; Australian Asthma Genetics Consortium Collaborators.

J Allergy Clin Immunol. 2017 Apr;139(4):1148-1157. doi: 10.1016/j.jaci.2016.07.017. Epub 2016 Aug 20.

9.

Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening antiviral immunity.

Lynch JP, Werder RB, Simpson J, Loh Z, Zhang V, Haque A, Spann K, Sly PD, Mazzone SB, Upham JW, Phipps S.

J Allergy Clin Immunol. 2016 Nov;138(5):1326-1337. doi: 10.1016/j.jaci.2016.02.039. Epub 2016 Apr 25.

PMID:
27236500
10.

Coinfection with Blood-Stage Plasmodium Promotes Systemic Type I Interferon Production during Pneumovirus Infection but Impairs Inflammation and Viral Control in the Lung.

Edwards CL, Zhang V, Werder RB, Best SE, Sebina I, James KR, Faleiro RJ, de Labastida Rivera F, Amante FH, Engwerda CR, Phipps S, Haque A.

Clin Vaccine Immunol. 2015 May;22(5):477-83. doi: 10.1128/CVI.00051-15. Epub 2015 Feb 25.

11.

IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice.

Spann KM, Loh Z, Lynch JP, Ullah A, Zhang V, Baturcam E, Werder RB, Khajornjiraphan N, Rudd P, Loo YM, Suhrbier A, Gale M Jr, Upham JW, Phipps S.

Am J Pathol. 2014 Jun;184(6):1795-806. doi: 10.1016/j.ajpath.2014.02.026. Epub 2014 Apr 13.

PMID:
24726644

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