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Items: 41


Hox5 Paralogous Genes Modulate Th2 Cell Function during Chronic Allergic Inflammation via Regulation of Gata3.

Ptaschinski C, Hrycaj SM, Schaller MA, Wellik DM, Lukacs NW.

J Immunol. 2017 Jul 15;199(2):501-509. doi: 10.4049/jimmunol.1601826. Epub 2017 Jun 2.


Hox11 Function Is Required for Region-Specific Fracture Repair.

Rux DR, Song JY, Pineault KM, Mandair GS, Swinehart IT, Schlientz AJ, Garthus KN, Goldstein SA, Kozloff KM, Wellik DM.

J Bone Miner Res. 2017 Aug;32(8):1750-1760. doi: 10.1002/jbmr.3166. Epub 2017 Jun 28.


Hox genes in the adult skeleton: Novel functions beyond embryonic development.

Rux DR, Wellik DM.

Dev Dyn. 2017 Apr;246(4):310-317. doi: 10.1002/dvdy.24482. Epub 2017 Jan 27. Review.


Regionally Restricted Hox Function in Adult Bone Marrow Multipotent Mesenchymal Stem/Stromal Cells.

Rux DR, Song JY, Swinehart IT, Pineault KM, Schlientz AJ, Trulik KG, Goldstein SA, Kozloff KM, Lucas D, Wellik DM.

Dev Cell. 2016 Dec 19;39(6):653-666. doi: 10.1016/j.devcel.2016.11.008. Epub 2016 Dec 8.


Fresh and Frozen Tissue-Engineered Three-Dimensional Bone-Ligament-Bone Constructs for Sheep Anterior Cruciate Ligament Repair Following a 2-Year Implantation.

Mahalingam V, Wojtys EM, Wellik DM, Arruda EM, Larkin LM.

Biores Open Access. 2016 Oct 1;5(1):289-298. eCollection 2016.


Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state.

Kherdjemil Y, Lalonde RL, Sheth R, Dumouchel A, de Martino G, Pineault KM, Wellik DM, Stadler HS, Akimenko MA, Kmita M.

Nature. 2016 Nov 3;539(7627):89-92. doi: 10.1038/nature19813. Epub 2016 Oct 5.


In vivo structural and cellular remodeling of engineered bone-ligament-bone constructs used for anterior cruciate ligament reconstruction in sheep.

Florida SE, VanDusen KW, Mahalingam VD, Schlientz AJ, Wojtys EM, Wellik DM, Larkin LM.

Connect Tissue Res. 2016 Nov;57(6):526-538. Epub 2016 May 16.


Hox6 genes modulate in vitro differentiation of mESCs to insulin-producing cells.

Larsen BM, Marty-Santos L, Newman M, Lukacs DT, Spence JR, Wellik DM.

In Vitro Cell Dev Biol Anim. 2016 Oct;52(9):974-982. Epub 2016 Jul 21.


Hox genes and evolution.

Hrycaj SM, Wellik DM.

F1000Res. 2016 May 10;5. pii: F1000 Faculty Rev-859. doi: 10.12688/f1000research.7663.1. eCollection 2016. Review.


Hox11 genes regulate postnatal longitudinal bone growth and growth plate proliferation.

Pineault KM, Swinehart IT, Garthus KN, Ho E, Yao Q, Schipani E, Kozloff KM, Wellik DM.

Biol Open. 2015 Oct 23;4(11):1538-48. doi: 10.1242/bio.012500.


Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation.

Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM.

Development. 2015 Nov 15;142(22):3859-68. doi: 10.1242/dev.126888. Epub 2015 Oct 8.


Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development.

Hrycaj SM, Dye BR, Baker NC, Larsen BM, Burke AC, Spence JR, Wellik DM.

Cell Rep. 2015 Aug 11;12(6):903-12. doi: 10.1016/j.celrep.2015.07.020. Epub 2015 Jul 30.


Fresh versus frozen engineered bone-ligament-bone grafts for sheep anterior cruciate ligament repair.

Mahalingam VD, Behbahani-Nejad N, Ronan EA, Olsen TJ, Smietana MJ, Wojtys EM, Wellik DM, Arruda EM, Larkin LM.

Tissue Eng Part C Methods. 2015 Jun;21(6):548-56. doi: 10.1089/ten.TEC.2014.0542. Epub 2014 Dec 29.


Allogeneic versus autologous derived cell sources for use in engineered bone-ligament-bone grafts in sheep anterior cruciate ligament repair.

Mahalingam VD, Behbahani-Nejad N, Horine SV, Olsen TJ, Smietana MJ, Wojtys EM, Wellik DM, Arruda EM, Larkin LM.

Tissue Eng Part A. 2015 Mar;21(5-6):1047-54. doi: 10.1089/ten.TEA.2014.0422. Epub 2015 Jan 8.


Hox genes and limb musculoskeletal development.

Pineault KM, Wellik DM.

Curr Osteoporos Rep. 2014 Dec;12(4):420-7. doi: 10.1007/s11914-014-0241-0. Review.


Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.

Walczak EM, Kuick R, Finco I, Bohin N, Hrycaj SM, Wellik DM, Hammer GD.

Mol Endocrinol. 2014 Sep;28(9):1471-86. doi: 10.1210/me.2014-1060. Epub 2014 Jul 16. Erratum in: Mol Endocrinol. 2015 Dec;29(12):1805.


Forward to the special issue on Hox/Tale transcription factors in development and disease.

Wellik DM, Torres M, Ros MA.

Dev Dyn. 2014 Jan;243(1):1-3. doi: 10.1002/dvdy.24098. Epub 2013 Dec 9. No abstract available.


Hox5 interacts with Plzf to restrict Shh expression in the developing forelimb.

Xu B, Hrycaj SM, McIntyre DC, Baker NC, Takeuchi JK, Jeannotte L, Gaber ZB, Novitch BG, Wellik DM.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19438-43. doi: 10.1073/pnas.1315075110. Epub 2013 Nov 11.


Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.

Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4456-64. doi: 10.1073/pnas.1311847110. Epub 2013 Nov 4.


Hox11 genes are required for regional patterning and integration of muscle, tendon and bone.

Swinehart IT, Schlientz AJ, Quintanilla CA, Mortlock DP, Wellik DM.

Development. 2013 Nov;140(22):4574-82. doi: 10.1242/dev.096693. Epub 2013 Oct 23.


Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis.

Boucherat O, Montaron S, Bérubé-Simard FA, Aubin J, Philippidou P, Wellik DM, Dasen JS, Jeannotte L.

Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15;304(12):L817-30. doi: 10.1152/ajplung.00006.2013. Epub 2013 Apr 12.


Changing topographic Hox expression in blood vessels results in regionally distinct vessel wall remodeling.

Pruett ND, Hajdu Z, Zhang J, Visconti RP, Kern MJ, Wellik DM, Majesky MW, Awgulewitsch A.

Biol Open. 2012 May 15;1(5):430-5. doi: 10.1242/bio.2012039. Epub 2012 Mar 20.


Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma.

Yallowitz AR, Hrycaj SM, Short KM, Smyth IM, Wellik DM.

PLoS One. 2011;6(8):e23410. doi: 10.1371/journal.pone.0023410. Epub 2011 Aug 16.


The role of Pax2 in mouse prostate development.

Xu B, Hariharan A, Rakshit S, Dressler GR, Wellik DM.

Prostate. 2012 Feb 1;72(2):217-24. doi: 10.1002/pros.21424. Epub 2011 May 18.


Hox genes and kidney development.

Wellik DM.

Pediatr Nephrol. 2011 Sep;26(9):1559-65. doi: 10.1007/s00467-011-1902-1. Epub 2011 May 8. Review.


Axial Hox9 activity establishes the posterior field in the developing forelimb.

Xu B, Wellik DM.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4888-91. doi: 10.1073/pnas.1018161108. Epub 2011 Mar 7.


Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements.

Koyama E, Yasuda T, Minugh-Purvis N, Kinumatsu T, Yallowitz AR, Wellik DM, Pacifici M.

Development. 2010 Nov;137(22):3795-800. doi: 10.1242/dev.053447.


Hox genes and regional patterning of the vertebrate body plan.

Mallo M, Wellik DM, Deschamps J.

Dev Biol. 2010 Aug 1;344(1):7-15. doi: 10.1016/j.ydbio.2010.04.024. Epub 2010 May 7. Review.


Hox11 paralogous genes are required for formation of wrist and ankle joints and articular surface organization.

Koyama E, Yasuda T, Wellik DM, Pacifici M.

Ann N Y Acad Sci. 2010 Mar;1192:307-16. doi: 10.1111/j.1749-6632.2009.05234.x.


Non-homeodomain regions of Hox proteins mediate activation versus repression of Six2 via a single enhancer site in vivo.

Yallowitz AR, Gong KQ, Swinehart IT, Nelson LT, Wellik DM.

Dev Biol. 2009 Nov 1;335(1):156-65. doi: 10.1016/j.ydbio.2009.08.020. Epub 2009 Aug 28.


Hox genes and vertebrate axial pattern.

Wellik DM.

Curr Top Dev Biol. 2009;88:257-78. doi: 10.1016/S0070-2153(09)88009-5. Review.


Generation and expression of a Hoxa11eGFP targeted allele in mice.

Nelson LT, Rakshit S, Sun H, Wellik DM.

Dev Dyn. 2008 Nov;237(11):3410-6. doi: 10.1002/dvdy.21756.


A Hox-Eya-Pax complex regulates early kidney developmental gene expression.

Gong KQ, Yallowitz AR, Sun H, Dressler GR, Wellik DM.

Mol Cell Biol. 2007 Nov;27(21):7661-8. Epub 2007 Sep 4.


Hox patterning of the vertebrate axial skeleton.

Wellik DM.

Dev Dyn. 2007 Sep;236(9):2454-63. Review.


Hox patterning of the vertebrate rib cage.

McIntyre DC, Rakshit S, Yallowitz AR, Loken L, Jeannotte L, Capecchi MR, Wellik DM.

Development. 2007 Aug;134(16):2981-9. Epub 2007 Jul 11.


Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton.

Wellik DM, Capecchi MR.

Science. 2003 Jul 18;301(5631):363-7.


Hox11 paralogous genes are essential for metanephric kidney induction.

Wellik DM, Hawkes PJ, Capecchi MR.

Genes Dev. 2002 Jun 1;16(11):1423-32.


Identification of a new all-trans-retinol metabolite produced through a new retinol metabolic pathway.

Jia X, Sicinski RR, Wellik DM, Tadikonda P, Schnoes HK, DeLuca HF.

Biochemistry. 1998 Apr 28;37(17):5974-80.


Retinol is specifically required during midgestation for neonatal survival.

Wellik DM, Norback DH, DeLuca HF.

Am J Physiol. 1997 Jan;272(1 Pt 1):E25-9.


Metabolites of all-trans-retinol in day 10 conceptuses of vitamin A-deficient rats.

Wellik DM, DeLuca HF.

Arch Biochem Biophys. 1996 Jun 15;330(2):355-62.


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