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Items: 36


Re-thinking the preclinical development of GBM therapeutics.

Cosset É, Weis SM, Cheresh DA.

Oncoscience. 2018 Feb 23;5(1-2):11-12. doi: 10.18632/oncoscience.396. eCollection 2018 Jan. No abstract available.


Intestinal parasitism among waste pickers in Mato Grosso do Sul, Midwest Brazil.

Higa MG Júnior, Cardoso WM, Weis SMDS, França AO, Pontes ERJC, Silva PVD, Oliveira MP, Dorval MEMC.

Rev Inst Med Trop Sao Paulo. 2017 Dec 21;59:e87. doi: 10.1590/S1678-9946201759087.


Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma.

Cosset É, Ilmjärv S, Dutoit V, Elliott K, von Schalscha T, Camargo MF, Reiss A, Moroishi T, Seguin L, Gomez G, Moo JS, Preynat-Seauve O, Krause KH, Chneiweiss H, Sarkaria JN, Guan KL, Dietrich PY, Weis SM, Mischel PS, Cheresh DA.

Cancer Cell. 2017 Dec 11;32(6):856-868.e5. doi: 10.1016/j.ccell.2017.10.016. Epub 2017 Nov 30.


Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers.

Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA.

Cancer Discov. 2017 Dec;7(12):1464-1479. doi: 10.1158/2159-8290.CD-17-0539. Epub 2017 Sep 11.


MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment.

Wilson R, Espinosa-Diez C, Kanner N, Chatterjee N, Ruhl R, Hipfinger C, Advani SJ, Li J, Khan OF, Franovic A, Weis SM, Kumar S, Coussens LM, Anderson DG, Chen CC, Cheresh DA, Anand S.

Nat Commun. 2016 Nov 25;7:13597. doi: 10.1038/ncomms13597.


Kinase-independent role for CRAF-driving tumour radioresistance via CHK2.

Advani SJ, Camargo MF, Seguin L, Mielgo A, Anand S, Hicks AM, Aguilera J, Franovic A, Weis SM, Cheresh DA.

Nat Commun. 2015 Sep 3;6:8154. doi: 10.1038/ncomms9154.


Glioblastomas require integrin αvβ3/PAK4 signaling to escape senescence.

Franovic A, Elliott KC, Seguin L, Camargo MF, Weis SM, Cheresh DA.

Cancer Res. 2015 Nov 1;75(21):4466-73. doi: 10.1158/0008-5472.CAN-15-0988. Epub 2015 Aug 21.


Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance.

Seguin L, Desgrosellier JS, Weis SM, Cheresh DA.

Trends Cell Biol. 2015 Apr;25(4):234-40. doi: 10.1016/j.tcb.2014.12.006. Epub 2015 Jan 5. Review.


Targeting the Achilles' heel of drug-resistant cancer stem cells.

Seguin L, Gozo M, Weis SM, Cheresh DA.

Cell Cycle. 2014;13(13):2017-8. doi: 10.4161/cc.29460. Epub 2014 Jun 6. No abstract available.


Variety in the tumor microenvironment: integrin splicing regulates stemness.

Seguin L, Weis SM, Cheresh DA.

Cell Stem Cell. 2014 May 1;14(5):557-8. doi: 10.1016/j.stem.2014.04.011.


An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.

Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA.

Nat Cell Biol. 2014 May;16(5):457-68. doi: 10.1038/ncb2953. Epub 2014 Apr 20.


A wake-up call for hibernating tumour cells.

Weis SM, Cheresh DA.

Nat Cell Biol. 2013 Jul;15(7):721-3. doi: 10.1038/ncb2794.


Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.

Lim ST, Miller NL, Chen XL, Tancioni I, Walsh CT, Lawson C, Uryu S, Weis SM, Cheresh DA, Schlaepfer DD.

J Cell Biol. 2012 Jun 25;197(7):907-19. doi: 10.1083/jcb.201109067.


EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1.

Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA.

PLoS One. 2012;7(5):e36753. doi: 10.1371/journal.pone.0036753. Epub 2012 May 7.


VEGF-induced vascular permeability is mediated by FAK.

Chen XL, Nam JO, Jean C, Lawson C, Walsh CT, Goka E, Lim ST, Tomar A, Tancioni I, Uryu S, Guan JL, Acevedo LM, Weis SM, Cheresh DA, Schlaepfer DD.

Dev Cell. 2012 Jan 17;22(1):146-57. doi: 10.1016/j.devcel.2011.11.002.


αV integrins in angiogenesis and cancer.

Weis SM, Cheresh DA.

Cold Spring Harb Perspect Med. 2011 Sep;1(1):a006478. doi: 10.1101/cshperspect.a006478. Review.


Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.

Scheppke L, Murphy EA, Zarpellon A, Hofmann JJ, Merkulova A, Shields DJ, Weis SM, Byzova TV, Ruggeri ZM, Iruela-Arispe ML, Cheresh DA.

Blood. 2012 Mar 1;119(9):2149-58. doi: 10.1182/blood-2011-04-348706. Epub 2011 Dec 1.


A MEK-independent role for CRAF in mitosis and tumor progression.

Mielgo A, Seguin L, Huang M, Camargo MF, Anand S, Franovic A, Weis SM, Advani SJ, Murphy EA, Cheresh DA.

Nat Med. 2011 Nov 13;17(12):1641-5. doi: 10.1038/nm.2464.


Tumor angiogenesis: molecular pathways and therapeutic targets.

Weis SM, Cheresh DA.

Nat Med. 2011 Nov 7;17(11):1359-70. doi: 10.1038/nm.2537. Review.


Evaluation of VEGF-induced vascular permeability in mice.

Weis SM.

Methods Mol Biol. 2011;763:403-15. doi: 10.1007/978-1-61779-191-8_27.


A Src family kinase inhibitor improves survival in experimental acute liver failure associated with elevated cerebral and circulating vascular endothelial growth factor levels.

Aspinall RJ, Weis SM, Barnes L, Lutu-Fuga K, Bylund DJ, Pockros PJ, Cheresh DA.

Liver Int. 2011 Sep;31(8):1222-30. doi: 10.1111/j.1478-3231.2011.02554.x. Epub 2011 Jun 7.


MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis.

Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields DJ, Lindquist JN, Lapinski PE, King PD, Weis SM, Cheresh DA.

Nat Med. 2010 Aug;16(8):909-14. doi: 10.1038/nm.2186. Epub 2010 Aug 1.


Agonizing integrin antagonists?

Weis SM, Stupack DG, Cheresh DA.

Cancer Cell. 2009 May 5;15(5):359-61. doi: 10.1016/j.ccr.2009.04.005.


Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis.

Ricono JM, Huang M, Barnes LA, Lau SK, Weis SM, Schlaepfer DD, Hanks SK, Cheresh DA.

Cancer Res. 2009 Feb 15;69(4):1383-91. doi: 10.1158/0008-5472.CAN-08-3612. Epub 2009 Feb 10.


Chapter 5. Evaluating vascular leak in vivo.

Weis SM.

Methods Enzymol. 2008;444:99-114. doi: 10.1016/S0076-6879(08)02805-X.


Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis.

Murphy EA, Majeti BK, Barnes LA, Makale M, Weis SM, Lutu-Fuga K, Wrasidlo W, Cheresh DA.

Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9343-8. doi: 10.1073/pnas.0803728105. Epub 2008 Jul 7.


Robo4 counteracts VEGF signaling.

Acevedo LM, Weis SM, Cheresh DA.

Nat Med. 2008 Apr;14(4):372-3. doi: 10.1038/nm0408-372. No abstract available.


Vascular permeability in cardiovascular disease and cancer.

Weis SM.

Curr Opin Hematol. 2008 May;15(3):243-9. doi: 10.1097/MOH.0b013e3282f97d86. Review.


Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.

Weis SM, Lim ST, Lutu-Fuga KM, Barnes LA, Chen XL, Göthert JR, Shen TL, Guan JL, Schlaepfer DD, Cheresh DA.

J Cell Biol. 2008 Apr 7;181(1):43-50. doi: 10.1083/jcb.200710038.


Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor.

Acevedo LM, Barillas S, Weis SM, Göthert JR, Cheresh DA.

Blood. 2008 Mar 1;111(5):2674-80. doi: 10.1182/blood-2007-08-110205. Epub 2008 Jan 7.


Evaluating integrin function in models of angiogenesis and vascular permeability.

Weis SM.

Methods Enzymol. 2007;426:505-28. Review.


Cooperation between VEGF and beta3 integrin during cardiac vascular development.

Weis SM, Lindquist JN, Barnes LA, Lutu-Fuga KM, Cui J, Wood MR, Cheresh DA.

Blood. 2007 Mar 1;109(5):1962-70. Epub 2006 Oct 24.


Pathophysiological consequences of VEGF-induced vascular permeability.

Weis SM, Cheresh DA.

Nature. 2005 Sep 22;437(7058):497-504.


A role for decorin in the remodeling of myocardial infarction.

Weis SM, Zimmerman SD, Shah M, Covell JW, Omens JH, Ross J Jr, Dalton N, Jones Y, Reed CC, Iozzo RV, McCulloch AD.

Matrix Biol. 2005 Jun;24(4):313-24.


Oesophageal morphometry and residual strain in a mouse model of osteogenesis imperfecta.

Gregersen H, Weis SM, McCulloch AD.

Neurogastroenterol Motil. 2001 Oct;13(5):457-64.


Myocardial mechanics and collagen structure in the osteogenesis imperfecta murine (oim).

Weis SM, Emery JL, Becker KD, McBride DJ Jr, Omens JH, McCulloch AD.

Circ Res. 2000 Oct 13;87(8):663-9.

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