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Items: 1 to 50 of 84

1.

The Discovery of Wild Date Palms in Oman Reveals a Complex Domestication History Involving Centers in the Middle East and Africa.

Gros-Balthazard M, Galimberti M, Kousathanas A, Newton C, Ivorra S, Paradis L, Vigouroux Y, Carter R, Tengberg M, Battesti V, Santoni S, Falquet L, Pintaud JC, Terral JF, Wegmann D.

Curr Biol. 2017 Jul 24;27(14):2211-2218.e8. doi: 10.1016/j.cub.2017.06.045. Epub 2017 Jul 14.

PMID:
28712568
2.

Inference of Evolutionary Jumps in Large Phylogenies using Lévy Processes.

Duchen P, Leuenberger C, Szilágyi SM, Harmon L, Eastman J, Schweizer M, Wegmann D.

Syst Biol. 2017 Nov 1;66(6):950-963. doi: 10.1093/sysbio/syx028.

3.

Normalisation against Circadian and Age-Related Disturbances Enables Robust Detection of Gene Expression Changes in Liver of Aged Mice.

Fonseca Costa SS, Wegmann D, Ripperger JA.

PLoS One. 2017 Jan 9;12(1):e0169615. doi: 10.1371/journal.pone.0169615. eCollection 2017.

4.

Inferring Heterozygosity from Ancient and Low Coverage Genomes.

Kousathanas A, Leuenberger C, Link V, Sell C, Burger J, Wegmann D.

Genetics. 2017 Jan;205(1):317-332. doi: 10.1534/genetics.116.189985. Epub 2016 Nov 7.

5.

Early Neolithic genomes from the eastern Fertile Crescent.

Broushaki F, Thomas MG, Link V, López S, van Dorp L, Kirsanow K, Hofmanová Z, Diekmann Y, Cassidy LM, Díez-Del-Molino D, Kousathanas A, Sell C, Robson HK, Martiniano R, Blöcher J, Scheu A, Kreutzer S, Bollongino R, Bobo D, Davudi H, Munoz O, Currat M, Abdi K, Biglari F, Craig OE, Bradley DG, Shennan S, Veeramah K, Mashkour M, Wegmann D, Hellenthal G, Burger J.

Science. 2016 Jul 29;353(6298):499-503. doi: 10.1126/science.aaf7943. Epub 2016 Jul 14.

6.

Early farmers from across Europe directly descended from Neolithic Aegeans.

Hofmanová Z, Kreutzer S, Hellenthal G, Sell C, Diekmann Y, Díez-Del-Molino D, van Dorp L, López S, Kousathanas A, Link V, Kirsanow K, Cassidy LM, Martiniano R, Strobel M, Scheu A, Kotsakis K, Halstead P, Triantaphyllou S, Kyparissi-Apostolika N, Urem-Kotsou D, Ziota C, Adaktylou F, Gopalan S, Bobo DM, Winkelbach L, Blöcher J, Unterländer M, Leuenberger C, Çilingiroğlu Ç, Horejs B, Gerritsen F, Shennan SJ, Bradley DG, Currat M, Veeramah KR, Wegmann D, Thomas MG, Papageorgopoulou C, Burger J.

Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):6886-91. doi: 10.1073/pnas.1523951113. Epub 2016 Jun 6.

7.

Likelihood-Free Inference in High-Dimensional Models.

Kousathanas A, Leuenberger C, Helfer J, Quinodoz M, Foll M, Wegmann D.

Genetics. 2016 Jun;203(2):893-904. doi: 10.1534/genetics.116.187567. Epub 2016 Apr 6.

8.

An Approximate Markov Model for the Wright-Fisher Diffusion and Its Application to Time Series Data.

Ferrer-Admetlla A, Leuenberger C, Jensen JD, Wegmann D.

Genetics. 2016 Jun;203(2):831-46. doi: 10.1534/genetics.115.184598. Epub 2016 Apr 2.

9.

Selection against recombinant hybrids maintains reproductive isolation in hybridizing Populus species despite F1 fertility and recurrent gene flow.

Christe C, Stölting KN, Bresadola L, Fussi B, Heinze B, Wegmann D, Lexer C.

Mol Ecol. 2016 Jun;25(11):2482-98. doi: 10.1111/mec.13587. Epub 2016 Mar 28.

PMID:
26880192
10.

Prospects and challenges for the conservation of farm animal genomic resources, 2015-2025.

Bruford MW, Ginja C, Hoffmann I, Joost S, Orozco-terWengel P, Alberto FJ, Amaral AJ, Barbato M, Biscarini F, Colli L, Costa M, Curik I, Duruz S, Ferenčaković M, Fischer D, Fitak R, Groeneveld LF, Hall SJ, Hanotte O, Hassan FU, Helsen P, Iacolina L, Kantanen J, Leempoel K, Lenstra JA, Ajmone-Marsan P, Masembe C, Megens HJ, Miele M, Neuditschko M, Nicolazzi EL, Pompanon F, Roosen J, Sevane N, Smetko A, Štambuk A, Streeter I, Stucki S, Supakorn C, Telo Da Gama L, Tixier-Boichard M, Wegmann D, Zhan X.

Front Genet. 2015 Oct 21;6:314. doi: 10.3389/fgene.2015.00314. eCollection 2015.

11.

Drosophila suzukii: the genetic footprint of a recent, worldwide invasion.

Adrion JR, Kousathanas A, Pascual M, Burrack HJ, Haddad NM, Bergland AO, Machado H, Sackton TB, Schlenke TA, Watada M, Wegmann D, Singh ND.

Mol Biol Evol. 2014 Dec;31(12):3148-63. doi: 10.1093/molbev/msu246. Epub 2014 Aug 25.

12.

Postglacial expansion and not human influence best explains the population structure in the endangered kea (Nestor notabilis).

Dussex N, Wegmann D, Robertson BC.

Mol Ecol. 2014 May;23(9):2193-209. doi: 10.1111/mec.12729. Epub 2014 Apr 11.

PMID:
24684223
13.

Demographic history of a recent invasion of house mice on the isolated Island of Gough.

Gray MM, Wegmann D, Haasl RJ, White MA, Gabriel SI, Searle JB, Cuthbert RJ, Ryan PG, Payseur BA.

Mol Ecol. 2014 Apr;23(8):1923-39. doi: 10.1111/mec.12715. Epub 2014 Apr 3.

14.

Influenza virus drug resistance: a time-sampled population genetics perspective.

Foll M, Poh YP, Renzette N, Ferrer-Admetlla A, Bank C, Shim H, Malaspinas AS, Ewing G, Liu P, Wegmann D, Caffrey DR, Zeldovich KB, Bolon DN, Wang JP, Kowalik TF, Schiffer CA, Finberg RW, Jensen JD.

PLoS Genet. 2014 Feb 27;10(2):e1004185. doi: 10.1371/journal.pgen.1004185. eCollection 2014 Feb.

15.

Analysis of rare variant population structure in Europeans explains differential stratification of gene-based tests.

Zawistowski M, Reppell M, Wegmann D, St Jean PL, Ehm MG, Nelson MR, Novembre J, Zöllner S.

Eur J Hum Genet. 2014 Sep;22(9):1137-44. doi: 10.1038/ejhg.2013.297. Epub 2014 Jan 8.

16.

Recipient of the 2013 Molecular Ecology Prize: Laurent Excoffier.

Wegmann D, Currat M.

Mol Ecol. 2014 Jan;23(1):16-9. doi: 10.1111/mec.12604. No abstract available.

PMID:
24283664
17.

The influence of genomic context on mutation patterns in the human genome inferred from rare variants.

Schaibley VM, Zawistowski M, Wegmann D, Ehm MG, Nelson MR, St Jean PL, Abecasis GR, Novembre J, Zöllner S, Li JZ.

Genome Res. 2013 Dec;23(12):1974-84. doi: 10.1101/gr.154971.113. Epub 2013 Aug 29.

18.

Inferring the geographic mode of speciation by contrasting autosomal and sex-linked genetic diversity.

Chu JH, Wegmann D, Yeh CF, Lin RC, Yang XJ, Lei FM, Yao CT, Zou FS, Li SH.

Mol Biol Evol. 2013 Nov;30(11):2519-30. doi: 10.1093/molbev/mst140. Epub 2013 Aug 16.

PMID:
23955517
19.

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.

Nelson MR, Wegmann D, Ehm MG, Kessner D, St Jean P, Verzilli C, Shen J, Tang Z, Bacanu SA, Fraser D, Warren L, Aponte J, Zawistowski M, Liu X, Zhang H, Zhang Y, Li J, Li Y, Li L, Woollard P, Topp S, Hall MD, Nangle K, Wang J, Abecasis G, Cardon LR, Zöllner S, Whittaker JC, Chissoe SL, Novembre J, Mooser V.

Science. 2012 Jul 6;337(6090):100-4. doi: 10.1126/science.1217876. Epub 2012 May 17.

20.

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis.

Stahl EA, Wegmann D, Trynka G, Gutierrez-Achury J, Do R, Voight BF, Kraft P, Chen R, Kallberg HJ, Kurreeman FA; Diabetes Genetics Replication and Meta-analysis Consortium; Myocardial Infarction Genetics Consortium, Kathiresan S, Wijmenga C, Gregersen PK, Alfredsson L, Siminovitch KA, Worthington J, de Bakker PI, Raychaudhuri S, Plenge RM.

Nat Genet. 2012 Mar 25;44(5):483-9. doi: 10.1038/ng.2232.

PMID:
22446960
21.

Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe.

Rubio JP, Topp S, Warren L, St Jean PL, Wegmann D, Kessner D, Novembre J, Shen J, Fraser D, Aponte J, Nangle K, Cardon LR, Ehm MG, Chissoe SL, Whittaker JC, Nelson MR, Mooser VE.

Hum Mutat. 2012 Jul;33(7):1087-98. doi: 10.1002/humu.22075. Epub 2012 Apr 4.

22.

Fitting models of continuous trait evolution to incompletely sampled comparative data using approximate Bayesian computation.

Slater GJ, Harmon LJ, Wegmann D, Joyce P, Revell LJ, Alfaro ME.

Evolution. 2012 Mar;66(3):752-762. doi: 10.1111/j.1558-5646.2011.01474.x. Epub 2011 Oct 21.

PMID:
22380438
23.

An early divergence of KhoeSan ancestors from those of other modern humans is supported by an ABC-based analysis of autosomal resequencing data.

Veeramah KR, Wegmann D, Woerner A, Mendez FL, Watkins JC, Destro-Bisol G, Soodyall H, Louie L, Hammer MF.

Mol Biol Evol. 2012 Feb;29(2):617-30. doi: 10.1093/molbev/msr212. Epub 2011 Sep 1.

24.

Recombination rates in admixed individuals identified by ancestry-based inference.

Wegmann D, Kessner DE, Veeramah KR, Mathias RA, Nicolae DL, Yanek LR, Sun YV, Torgerson DG, Rafaels N, Mosley T, Becker LC, Ruczinski I, Beaty TH, Kardia SL, Meyers DA, Barnes KC, Becker DM, Freimer NB, Novembre J.

Nat Genet. 2011 Jul 20;43(9):847-53. doi: 10.1038/ng.894.

PMID:
21775992
25.

Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity.

Veeramah KR, Tönjes A, Kovacs P, Gross A, Wegmann D, Geary P, Gasperikova D, Klimes I, Scholz M, Novembre J, Stumvoll M.

Eur J Hum Genet. 2011 Sep;19(9):995-1001. doi: 10.1038/ejhg.2011.65. Epub 2011 May 11.

26.

Historical sampling reveals dramatic demographic changes in western gorilla populations.

Thalmann O, Wegmann D, Spitzner M, Arandjelovic M, Guschanski K, Leuenberger C, Bergl RA, Vigilant L.

BMC Evol Biol. 2011 Apr 1;11:85. doi: 10.1186/1471-2148-11-85.

27.

Distinguishing between population bottleneck and population subdivision by a Bayesian model choice procedure.

Peter BM, Wegmann D, Excoffier L.

Mol Ecol. 2010 Nov;19(21):4648-60. doi: 10.1111/j.1365-294X.2010.04783.x. Epub 2010 Aug 23.

PMID:
20735743
28.

ABCtoolbox: a versatile toolkit for approximate Bayesian computations.

Wegmann D, Leuenberger C, Neuenschwander S, Excoffier L.

BMC Bioinformatics. 2010 Mar 4;11:116. doi: 10.1186/1471-2105-11-116.

29.

Bayesian inference of the demographic history of chimpanzees.

Wegmann D, Excoffier L.

Mol Biol Evol. 2010 Jun;27(6):1425-35. doi: 10.1093/molbev/msq028. Epub 2010 Jan 29.

PMID:
20118191
30.

A statistical evaluation of models for the initial settlement of the american continent emphasizes the importance of gene flow with Asia.

Ray N, Wegmann D, Fagundes NJ, Wang S, Ruiz-Linares A, Excoffier L.

Mol Biol Evol. 2010 Feb;27(2):337-45. doi: 10.1093/molbev/msp238. Epub 2009 Oct 5.

PMID:
19805438
31.

Bayesian computation and model selection without likelihoods.

Leuenberger C, Wegmann D.

Genetics. 2010 Jan;184(1):243-52. doi: 10.1534/genetics.109.109058. Epub 2009 Sep 28.

32.

Prevalence of undernutrition on admission to Swiss hospitals.

Imoberdorf R, Meier R, Krebs P, Hangartner PJ, Hess B, Stäubli M, Wegmann D, Rühlin M, Ballmer PE.

Clin Nutr. 2010 Feb;29(1):38-41. doi: 10.1016/j.clnu.2009.06.005. Epub 2009 Jul 1.

PMID:
19573958
33.

Efficient approximate Bayesian computation coupled with Markov chain Monte Carlo without likelihood.

Wegmann D, Leuenberger C, Excoffier L.

Genetics. 2009 Aug;182(4):1207-18. doi: 10.1534/genetics.109.102509. Epub 2009 Jun 8.

34.

Large allele frequency differences between human continental groups are more likely to have occurred by drift during range expansions than by selection.

Hofer T, Ray N, Wegmann D, Excoffier L.

Ann Hum Genet. 2009 Jan;73(1):95-108. doi: 10.1111/j.1469-1809.2008.00489.x. Epub 2008 Nov 22.

35.

Width of gene expression profile drives alternative splicing.

Wegmann D, Dupanloup I, Excoffier L.

PLoS One. 2008;3(10):e3587. doi: 10.1371/journal.pone.0003587. Epub 2008 Oct 31.

36.

Pancreatic resection pain management: is combining PCA therapy and a continuous local infusion of 0.5% ropivacaine beneficial?

Thompson TK, Hutchison RW, Wegmann DJ, Shires GT 3rd, Beecherl E.

Pancreas. 2008 Jul;37(1):103-4. doi: 10.1097/MPA.0b013e31816074b7. No abstract available.

PMID:
18580453
37.

Mutation of a single residue, beta-glutamate-20, alters protein-lipid interactions of light harvesting complex II.

Kwa LG, Wegmann D, Brügger B, Wieland FT, Wanner G, Braun P.

Mol Microbiol. 2008 Jan;67(1):63-77. Epub 2007 Nov 22.

38.

Role of neutrophils in a mouse model of halothane-induced liver injury.

You Q, Cheng L, Reilly TP, Wegmann D, Ju C.

Hepatology. 2006 Dec;44(6):1421-31.

PMID:
17133481
39.

Molecular diversity after a range expansion in heterogeneous environments.

Wegmann D, Currat M, Excoffier L.

Genetics. 2006 Dec;174(4):2009-20. Epub 2006 Oct 8.

40.

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.

Nakayama M, Abiru N, Moriyama H, Babaya N, Liu E, Miao D, Yu L, Wegmann DR, Hutton JC, Elliott JF, Eisenbarth GS.

Nature. 2005 May 12;435(7039):220-3.

41.

Increased NF-kappa B activity in B cells and bone marrow-derived dendritic cells from NOD mice.

Wheat W, Kupfer R, Gutches DG, Rayat GR, Beilke J, Scheinman RI, Wegmann DR.

Eur J Immunol. 2004 May;34(5):1395-404.

42.

Clinical testing of contrast sensitivity in children: age-related norms and validity.

Leat SJ, Wegmann D.

Optom Vis Sci. 2004 Apr;81(4):245-54.

PMID:
15097766
43.

HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes.

Kelemen K, Gottlieb PA, Putnam AL, Davidson HW, Wegmann DR, Hutton JC.

J Immunol. 2004 Mar 15;172(6):3955-62.

44.

Novel isotypic gamma/zeta subunits reveal three coatomer complexes in mammals.

Wegmann D, Hess P, Baier C, Wieland FT, Reinhard C.

Mol Cell Biol. 2004 Feb;24(3):1070-80.

45.

Insulin autoimmunity: prediction/precipitation/prevention type 1A diabetes.

Eisenbarth GS, Moriyama H, Robles DT, Liu E, Yu L, Babu S, Redondo MJ, Gottlieb P, Wegmann D, Rewers M.

Autoimmun Rev. 2002 May;1(3):139-45. Review. Erratum in: Autoimmun Rev. 2006 May;5(5):364. Redondo, Maria [corrected to Redondo, Maria J].

PMID:
12849007
46.

Spontaneous peripheral T-cell responses to the IA-2beta (phogrin) autoantigen in young nonobese diabetic mice.

Achenbach P, Kelemen K, Wegmann DR, Hutton JC.

J Autoimmun. 2002 Nov;19(3):111-6.

PMID:
12419281
47.

A comparative evaluation of the perceptions of health of elders of different multicultural backgrounds.

Hakim H, Wegmann DJ.

J Community Health Nurs. 2002 Fall;19(3):161-71.

PMID:
12378893
48.

Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide.

Alleva DG, Gaur A, Jin L, Wegmann D, Gottlieb PA, Pahuja A, Johnson EB, Motheral T, Putnam A, Crowe PD, Ling N, Boehme SA, Conlon PJ.

Diabetes. 2002 Jul;51(7):2126-34.

49.
50.

Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop.

Kaufman DL, Tisch R, Sarvetnick N, Chatenoud L, Harrison LC, Haskins K, Quinn A, Sercarz E, Singh B, von Herrath M, Wegmann D, Wen L, Zekzer D.

Diabetes. 2001 Nov;50(11):2459-63. Review.

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