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Items: 1 to 50 of 310

1.

Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study.

Vogelmeier CF, Chapman KR, Miravitlles M, Roche N, Vestbo J, Thach C, Banerji D, Fogel R, Patalano F, Olsson P, Kostikas K, Wedzicha JA.

Int J Chron Obstruct Pulmon Dis. 2018 Apr 10;13:1125-1134. doi: 10.2147/COPD.S160011. eCollection 2018.

PMID:
29692607
2.

Patient Reported Outcomes for the Detection, Quantification and Evaluation of Chronic Obstructive Pulmonary Disease Exacerbations.

Mackay AJ, Kostikas K, Murray L, Martinez FJ, Miravitlles M, Donaldson G, Banerji D, Patalano F, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Apr 19. doi: 10.1164/rccm.201712-2482CI. [Epub ahead of print]

PMID:
29671615
3.

Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists.

Bewley MA, Budd RC, Ryan E, Cole J, Collini P, Marshall J, Kolsum U, Beech G, Emes RD, Tcherniaeva I, Berbers GAM, Walmsley SR, Donaldson G, Wedzicha JA, Kilty I, Rumsey W, Sanchez Y, Brightling CE, Donnelly LE, Barnes PJ, Singh D, Whyte MKB, Dockrell DH; COPDMAP.

Am J Respir Crit Care Med. 2018 Mar 16. doi: 10.1164/rccm.201705-0903OC. [Epub ahead of print]

PMID:
29547002
4.

Is Peer Review Still Anonymous?

Ritchie AI, Polkey MI, Donaldson GC, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Mar 14. doi: 10.1164/rccm.201711-2257LE. [Epub ahead of print] No abstract available.

PMID:
29537300
5.

Intensifying LABA/ICS Therapy at Acute COPD Exacerbations.

Wedzicha JA, Martinez FJ.

Am J Respir Crit Care Med. 2018 Feb 16. doi: 10.1164/rccm.201801-0202ED. [Epub ahead of print] No abstract available.

PMID:
29451809
6.

At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease.

Martinez FJ, Han MK, Allinson JP, Barr RG, Boucher RC, Calverley P, Celli BR, Christenson SA, Crystal RG, Fagerås M, Freeman CM, Groenke L, Hoffman EA, Kesimer M, Kostikas K, Paine Iii R, Rafii S, Rennard SI, Segal LN, Shaykhiev R, Stevenson C, Tal-Singer R, Vestbo J, Woodruff PG, Curtis JL, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Feb 6. doi: 10.1164/rccm.201710-2028PP. [Epub ahead of print]

PMID:
29406779
7.

Research Priorities in Pathophysiology for Sleep-disordered Breathing in Patients with Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Research Statement.

Malhotra A, Schwartz AR, Schneider H, Owens RL, DeYoung P, Han MK, Wedzicha JA, Hansel NN, Zeidler MR, Wilson KC, Badr MS; ATS Assembly on Sleep and Respiratory Neurobiology.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):289-299. doi: 10.1164/rccm.201712-2510ST.

PMID:
29388824
8.

Pulmonary rehabilitation for patients with COPD during and after an exacerbation-related hospitalisation: back to the future?

Wilson KC, Krishnan JA, Sliwinski P, Criner GJ, Miravitlles M, Hurst JR, Calverley PMA, Albert RK, Rigau D, Tonia T, Vestbo J, Papi A, Rabe KF, Anzueto A, Wedzicha JA.

Eur Respir J. 2018 Jan 11;51(1). pii: 1702577. doi: 10.1183/13993003.02577-2017. Print 2018 Jan. No abstract available.

PMID:
29326324
9.

Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.

Wang Z, Singh R, Miller BE, Tal-Singer R, Van Horn S, Tomsho L, Mackay A, Allinson JP, Webb AJ, Brookes AJ, George LM, Barker B, Kolsum U, Donnelly LE, Belchamber K, Barnes PJ, Singh D, Brightling CE, Donaldson GC, Wedzicha JA, Brown JR; COPDMAP.

Thorax. 2018 Apr;73(4):331-338. doi: 10.1136/thoraxjnl-2017-210741. Epub 2017 Dec 21.

10.

Reply to Cooper et al.: The Significance of Eosinophilic Inflammation in Chronic Obstructive Pulmonary Disease.

Roche N, Chapman KR, Vogelmeier CF, Herth FJF, Thach C, Fogel R, Olsson P, Patalano F, Banerji D, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Apr 1;197(7):968-969. doi: 10.1164/rccm.201710-2027LE. No abstract available.

PMID:
29140725
11.

Triple Therapy in COPD: What We Know and What We Don't.

Calverley PMA, Magnussen H, Miravitlles M, Wedzicha JA.

COPD. 2017 Dec;14(6):648-662. doi: 10.1080/15412555.2017.1389875. Epub 2017 Nov 9.

PMID:
29120273
12.

Dual Bronchodilation Response by Exacerbation History and Eosinophilia in the FLAME Study.

Papi A, Kostikas K, Wedzicha JA, Vogelmeier CF, Roche N, Shen S, Banerji D, Fogel R, Patalano F, Chapman KR.

Am J Respir Crit Care Med. 2017 Nov 3. doi: 10.1164/rccm.201709-1822LE. [Epub ahead of print] No abstract available.

PMID:
29099609
13.

Effect of erdosteine on the rate and duration of COPD exacerbations: the RESTORE study.

Dal Negro RW, Wedzicha JA, Iversen M, Fontana G, Page C, Cicero AF, Pozzi E, Calverley PMA; RESTORE group; RESTORE study.

Eur Respir J. 2017 Oct 12;50(4). pii: 1700711. doi: 10.1183/13993003.00711-2017. Print 2017 Oct.

14.

Prevention of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline.

Wedzicha JA, Calverley PMA, Albert RK, Anzueto A, Criner GJ, Hurst JR, Miravitlles M, Papi A, Rabe KF, Rigau D, Sliwinski P, Tonia T, Vestbo J, Wilson KC, Krishnan JA.

Eur Respir J. 2017 Sep 9;50(3). pii: 1602265. doi: 10.1183/13993003.02265-2016. Print 2017 Sep.

PMID:
28889106
15.

Airway Mucins in Chronic Obstructive Pulmonary Disease.

Wedzicha JA.

N Engl J Med. 2017 Sep 7;377(10):986-987. doi: 10.1056/NEJMe1707210. No abstract available.

PMID:
28877010
16.

Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease.

Osadnik CR, Tee VS, Carson-Chahhoud KV, Picot J, Wedzicha JA, Smith BJ.

Cochrane Database Syst Rev. 2017 Jul 13;7:CD004104. doi: 10.1002/14651858.CD004104.pub4. Review.

PMID:
28702957
17.

Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

Han MK, Quibrera PM, Carretta EE, Barr RG, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL, Criner G, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Krishnan JA, Martinez CH, Pirozzi CB, O'Neal WK, Rennard S, Tashkin DP, Wedzicha JA, Woodruff P, Paine R 3rd, Martinez FJ; SPIROMICS investigators.

Lancet Respir Med. 2017 Aug;5(8):619-626. doi: 10.1016/S2213-2600(17)30207-2. Epub 2017 Jun 28.

18.

Erratum to "Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary" [Arch Bronconeumol. 2017;53:128-49].

Vogelmeier CF, Criner GJ, Martínez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DMG, Varela MVL, Nishimura M, Roche N, Rodríguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agustí A.

Arch Bronconeumol. 2017 Jul;53(7):411-412. doi: 10.1016/j.arbres.2017.06.001. English, Spanish. No abstract available.

19.

Cardiovascular Disease Does Not Predict Exacerbation Rate or Mortality in Chronic Obstructive Pulmonary Disease.

Jones PW, Mullerova H, Agusti A, Decramer M, Adamek L, Raillard A, Zhu CQ, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):400-403. doi: 10.1164/rccm.201706-1066LE. No abstract available.

20.

Reply: What Should Be the Cutoff Value of Blood Eosinophilia as a Predictor of Inhaled Corticosteroid Responsiveness in Patients with Chronic Obstructive Pulmonary Disease?

Roche N, Chapman KR, Vogelmeier CF, Herth FJF, Thach C, Fogel R, Olsson P, Patalano F, Banerji D, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Nov 1;196(9):1230-1231. doi: 10.1164/rccm.201706-1105LE. No abstract available.

PMID:
28650724
21.

Update in Chronic Obstructive Pulmonary Disease 2016.

Allinson JP, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Aug 15;196(4):414-424. doi: 10.1164/rccm.201703-0588UP. Review. No abstract available.

22.

Combined Impact of Smoking and Early-Life Exposures on Adult Lung Function Trajectories.

Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):1021-1030. doi: 10.1164/rccm.201703-0506OC.

23.

Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation: A Randomized Clinical Trial.

Murphy PB, Rehal S, Arbane G, Bourke S, Calverley PMA, Crook AM, Dowson L, Duffy N, Gibson GJ, Hughes PD, Hurst JR, Lewis KE, Mukherjee R, Nickol A, Oscroft N, Patout M, Pepperell J, Smith I, Stradling JR, Wedzicha JA, Polkey MI, Elliott MW, Hart N.

JAMA. 2017 Jun 6;317(21):2177-2186. doi: 10.1001/jama.2017.4451.

24.

Blood and sputum eosinophils in COPD; relationship with bacterial load.

Kolsum U, Donaldson GC, Singh R, Barker BL, Gupta V, George L, Webb AJ, Thurston S, Brookes AJ, McHugh TD, Wedzicha JA, Brightling CE, Singh D.

Respir Res. 2017 May 8;18(1):88. doi: 10.1186/s12931-017-0570-5.

25.

AJRCCM: 100-Year Anniversary. The Long View and the Fast Lane.

Wedzicha JA, Brochard LJ, Martinez FD, Martinez FJ, Donaldson G.

Am J Respir Crit Care Med. 2017 May 1;195(9):1081-1085. doi: 10.1164/rccm.201703-0525ED. No abstract available.

26.

Blood Eosinophils and Response to Maintenance Chronic Obstructive Pulmonary Disease Treatment. Data from the FLAME Trial.

Roche N, Chapman KR, Vogelmeier CF, Herth FJF, Thach C, Fogel R, Olsson P, Patalano F, Banerji D, Wedzicha JA.

Am J Respir Crit Care Med. 2017 May 1;195(9):1189-1197. doi: 10.1164/rccm.201701-0193OC.

27.

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.

Vogelmeier CF, Criner GJ, Martínez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodríguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agustí A.

Arch Bronconeumol. 2017 Mar;53(3):128-149. doi: 10.1016/j.arbres.2017.02.001. Epub 2017 Mar 6. English, Spanish. Erratum in: Arch Bronconeumol. 2017 Jul;53(7):411-412.

28.

Prediction of Chronic Obstructive Pulmonary Disease Exacerbation Frequency. Clinical Parameters Are Still Better Than Biomarkers.

Donaldson GC, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Feb 15;195(4):415-416. doi: 10.1164/rccm.201610-2037ED. No abstract available.

29.

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.

Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A.

Eur Respir J. 2017 Mar 6;49(3). pii: 1700214. doi: 10.1183/13993003.00214-2017. Print 2017 Mar. Erratum in: Eur Respir J. 2017 Jun 22;49(6):.

PMID:
28182564
30.

Indacaterol/glycopyrronium versus salmeterol/fluticasone in Asian patients with COPD at a high risk of exacerbations: results from the FLAME study.

Wedzicha JA, Zhong N, Ichinose M, Humphries M, Fogel R, Thach C, Patalano F, Banerji D.

Int J Chron Obstruct Pulmon Dis. 2017 Jan 19;12:339-349. doi: 10.2147/COPD.S125058. eCollection 2017.

31.

Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.

Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A.

Respirology. 2017 Apr;22(3):575-601. doi: 10.1111/resp.13012. Epub 2017 Mar 7.

32.

Randomized Double-Blind Controlled Trial of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary Disease.

Mackay AJ, Patel ARC, Singh R, Sapsford RJ, Donaldson GC, Prasad N, Goehring UM, Nip TK, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Sep 1;196(5):656-659. doi: 10.1164/rccm.201612-2518LE. No abstract available.

33.

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary.

Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agustí A.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):557-582. doi: 10.1164/rccm.201701-0218PP.

34.

The role of complement activation in COPD exacerbation recovery.

Westwood JP, Mackay AJ, Donaldson G, Machin SJ, Wedzicha JA, Scully M.

ERJ Open Res. 2016 Oct 19;2(4). pii: 00027-2016. doi: 10.1183/23120541.00027-2016. eCollection 2016 Oct.

35.

AJRCCM 2017: 100-Year Anniversary.

Wedzicha JA.

Am J Respir Crit Care Med. 2017 Jan 1;195(1):1. doi: 10.1164/rccm.201612-2411ED. No abstract available.

PMID:
28035855
36.

Misspecification of at-risk periods and distributional assumptions in estimating COPD exacerbation rates: The resultant bias in treatment effect estimation.

Law M, Sweeting MJ, Donaldson GC, Wedzicha JA.

Pharm Stat. 2017 May;16(3):201-209. doi: 10.1002/pst.1798. Epub 2016 Dec 14.

37.

How Do Dual Long-Acting Bronchodilators Prevent Exacerbations of Chronic Obstructive Pulmonary Disease?

Beeh KM, Burgel PR, Franssen FME, Lopez-Campos JL, Loukides S, Hurst JR, Fležar M, Ulrik CS, Di Marco F, Stolz D, Valipour A, Casserly B, Ställberg B, Kostikas K, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):139-149. doi: 10.1164/rccm.201609-1794CI. Review.

38.

Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD.

Bewley MA, Belchamber KB, Chana KK, Budd RC, Donaldson G, Wedzicha JA, Brightling CE, Kilty I, Donnelly LE, Barnes PJ, Singh D, Whyte MK, Dockrell DH; COPDMAP.

PLoS One. 2016 Sep 28;11(9):e0163139. doi: 10.1371/journal.pone.0163139. eCollection 2016.

39.

Chronic Respiratory Symptoms with Normal Spirometry. A Reliable Clinical Entity?

Rodriguez-Roisin R, Han MK, Vestbo J, Wedzicha JA, Woodruff PG, Martinez FJ.

Am J Respir Crit Care Med. 2017 Jan 1;195(1):17-22. doi: 10.1164/rccm.201607-1376PP. No abstract available.

40.

Current Controversies in the Pharmacological Treatment of Chronic Obstructive Pulmonary Disease.

Singh D, Roche N, Halpin D, Agusti A, Wedzicha JA, Martinez FJ.

Am J Respir Crit Care Med. 2016 Sep 1;194(5):541-9. doi: 10.1164/rccm.201606-1179PP.

41.

Oral Phosphodiesterase-4 Inhibitors for Chronic Obstructive Pulmonary Disease "Super Exacerbators".

Wedzicha JA.

Am J Respir Crit Care Med. 2016 Sep 1;194(5):527-8. doi: 10.1164/rccm.201608-1566ED. No abstract available.

PMID:
27585375
42.

Indacaterol-Glycopyrronium for COPD.

Wedzicha JA, Banerji D, Vogelmeier CF.

N Engl J Med. 2016 Sep 1;375(9):899-900. doi: 10.1056/NEJMc1609305. No abstract available.

43.

Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD.

Wedzicha JA, Banerji D, Chapman KR, Vestbo J, Roche N, Ayers RT, Thach C, Fogel R, Patalano F, Vogelmeier CF; FLAME Investigators.

N Engl J Med. 2016 Jun 9;374(23):2222-34. doi: 10.1056/NEJMoa1516385. Epub 2016 May 15.

44.

Effect of Aclidinium Bromide on Exacerbations in Patients with Moderate-to-Severe COPD: A Pooled Analysis of Five Phase III, Randomized, Placebo-Controlled Studies.

Wedzicha JA, Agusti A, Donaldson G, Chuecos F, Lamarca R, Garcia Gil E.

COPD. 2016 Dec;13(6):669-676. Epub 2016 May 9.

45.

Eosinophils as Biomarkers of Chronic Obstructive Pulmonary Disease Exacerbation Risk. Maybe Just for Some?

Wedzicha JA.

Am J Respir Crit Care Med. 2016 May 1;193(9):937-8. doi: 10.1164/rccm.201601-0015ED. No abstract available.

46.

Physical activity and exercise capacity in patients with moderate COPD exacerbations.

Alahmari AD, Kowlessar BS, Patel AR, Mackay AJ, Allinson JP, Wedzicha JA, Donaldson GC.

Eur Respir J. 2016 Aug;48(2):340-9. doi: 10.1183/13993003.01105-2015. Epub 2016 Apr 28.

47.

Roflumilast: a review of its use in the treatment of COPD.

Wedzicha JA, Calverley PM, Rabe KF.

Int J Chron Obstruct Pulmon Dis. 2016 Jan 6;11:81-90. doi: 10.2147/COPD.S89849. eCollection 2016. Review.

48.

The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development.

Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA.

Am J Respir Crit Care Med. 2016 Mar 15;193(6):662-72. doi: 10.1164/rccm.201511-2210OC.

49.

Mechanisms of Chronic Obstructive Pulmonary Disease Exacerbations.

Wedzicha JA.

Ann Am Thorac Soc. 2015 Nov;12 Suppl 2:S157-9. doi: 10.1513/AnnalsATS.201507-427AW.

PMID:
26595732
50.

Mechanisms of Chronic Obstructive Pulmonary Disease Exacerbations.

Wedzicha JA.

Ann Am Thorac Soc. 2015 Nov;12(Suppl 2):S157-S159.

PMID:
26599578

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