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Items: 1 to 50 of 92

1.

Modeling treatment outcomes for patients with advanced ovarian cancer: Projected benefits of a test to optimize treatment selection.

Weaver DT, Raphel TJ, Melamed A, Rauh-Hain JA, Schorge JO, Knudsen AB, Pandharipande PV.

Gynecol Oncol. 2018 Feb 24. pii: S0090-8258(18)30126-4. doi: 10.1016/j.ygyno.2018.02.007. [Epub ahead of print]

PMID:
29486993
2.

Imaging Follow-up of Low-Risk Incidental Pancreas and Kidney Findings: Effects of Patient Age and Comorbidity on Projected Life Expectancy.

Raphel TJ, Weaver DT, Berland LL, Herts BR, Megibow AJ, Knudsen AB, Pandharipande PV.

Radiology. 2018 May;287(2):504-514. doi: 10.1148/radiol.2018171701. Epub 2018 Feb 5.

PMID:
29401040
3.

Management of a Case of Retinopathy of Prematurity With Poor Visualization of the Retina.

Bhatt A, Paul Chan RV, Weaver DT, Wagner RS.

J Pediatr Ophthalmol Strabismus. 2017 Sep 1;54(5):262-264. doi: 10.3928/01913913-20170613-01. No abstract available.

PMID:
28926661
4.

Inhibition of FAK kinase activity preferentially targets cancer stem cells.

Kolev VN, Tam WF, Wright QG, McDermott SP, Vidal CM, Shapiro IM, Xu Q, Wicha MS, Pachter JA, Weaver DT.

Oncotarget. 2017 Jun 16;8(31):51733-51747. doi: 10.18632/oncotarget.18517. eCollection 2017 Aug 1.

5.

The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma.

Begum A, Ewachiw T, Jung C, Huang A, Norberg KJ, Marchionni L, McMillan R, Penchev V, Rajeshkumar NV, Maitra A, Wood L, Wang C, Wolfgang C, DeJesus-Acosta A, Laheru D, Shapiro IM, Padval M, Pachter JA, Weaver DT, Rasheed ZA, Matsui W.

PLoS One. 2017 Jul 10;12(7):e0180181. doi: 10.1371/journal.pone.0180181. eCollection 2017.

6.

Characterization of an Lrp/AsnC family regulator SCO3361, controlling actinorhodin production and morphological development in Streptomyces coelicolor.

Liu J, Li J, Dong H, Chen Y, Wang Y, Wu H, Li C, Weaver DT, Zhang L, Zhang B.

Appl Microbiol Biotechnol. 2017 Jul;101(14):5773-5783. doi: 10.1007/s00253-017-8339-9. Epub 2017 Jun 11.

PMID:
28601893
7.

Focal Adhesion Kinase as a Potential Target in AML and MDS.

Carter BZ, Mak PY, Wang X, Yang H, Garcia-Manero G, Mak DH, Mu H, Ruvolo VR, Qiu Y, Coombes K, Zhang N, Ragon B, Weaver DT, Pachter JA, Kornblau S, Andreeff M.

Mol Cancer Ther. 2017 Jun;16(6):1133-1144. doi: 10.1158/1535-7163.MCT-16-0719. Epub 2017 Mar 7.

PMID:
28270436
8.

Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea.

Liu J, Chen Y, Wang W, Ren M, Wu P, Wang Y, Li C, Zhang L, Wu H, Weaver DT, Zhang B.

Metab Eng. 2017 Jan;39:29-37. doi: 10.1016/j.ymben.2016.10.012. Epub 2016 Oct 26.

PMID:
27794466
9.

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.

Jiang H, Hegde S, Knolhoff BL, Zhu Y, Herndon JM, Meyer MA, Nywening TM, Hawkins WG, Shapiro IM, Weaver DT, Pachter JA, Wang-Gillam A, DeNardo DG.

Nat Med. 2016 Aug;22(8):851-60. doi: 10.1038/nm.4123. Epub 2016 Jul 4.

10.

Synergism of FAK and tyrosine kinase inhibition in Ph+ B-ALL.

Churchman ML, Evans K, Richmond J, Robbins A, Jones L, Shapiro IM, Pachter JA, Weaver DT, Houghton PJ, Smith MA, Lock RB, Mullighan CG.

JCI Insight. 2016;1(4). pii: e86082. Epub 2016 Apr 7.

11.

Inactivation of SACE_3446, a TetR family transcriptional regulator, stimulates erythromycin production in Saccharopolyspora erythraea.

Wu H, Wang Y, Yuan L, Mao Y, Wang W, Zhu L, Wu P, Fu C, Müller R, Weaver DT, Zhang L, Zhang B.

Synth Syst Biotechnol. 2016 Feb 16;1(1):39-46. doi: 10.1016/j.synbio.2016.01.004. eCollection 2016 Mar.

12.

Prevention of Lower Eyelid Retraction in a Case of Inferior Rectus Muscle Recession.

DeRespinis PA, Strominger MB, Weaver DT, Wagner RS.

J Pediatr Ophthalmol Strabismus. 2016 Jan-Feb;53(1):5-6. doi: 10.3928/01913913-20160112-01. No abstract available.

PMID:
26835992
13.

In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea.

Wu H, Li W, Xin C, Zhang C, Wang Y, Ren S, Ren M, Zhao W, Yuan L, Xu Z, Yuan H, Geng M, Zhang L, Weaver DT, Zhang B.

Appl Microbiol Biotechnol. 2016 Mar;100(5):2257-66. doi: 10.1007/s00253-015-7036-9. Epub 2015 Nov 10.

PMID:
26552796
14.

Surgical management of a case of congenital fourth nerve palsy.

Kipp MA, Koller HP, Weaver DT.

J Pediatr Ophthalmol Strabismus. 2015 Jan-Feb;52(1):6-8. doi: 10.3928/01913913-20141230-01. No abstract available.

PMID:
25643364
15.

c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit.

Li D, Dong Q, Tao Q, Gu J, Cui Y, Jiang X, Yuan J, Li W, Xu R, Jin Y, Li P, Weaver DT, Ma Q, Liu X, Cao C.

Cell Rep. 2015 Feb 3;10(4):484-96. doi: 10.1016/j.celrep.2014.12.044. Epub 2015 Jan 22.

16.

Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method.

Wu H, Mao Y, Chen M, Pan H, Huang X, Ren M, Wu H, Li J, Xu Z, Yuan H, Geng M, Weaver DT, Zhang L, Zhang B.

Appl Microbiol Biotechnol. 2015 Mar;99(6):2683-92. doi: 10.1007/s00253-014-6255-9. Epub 2014 Dec 31.

PMID:
25549616
17.

PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells.

Kolev VN, Wright QG, Vidal CM, Ring JE, Shapiro IM, Ricono J, Weaver DT, Padval MV, Pachter JA, Xu Q.

Cancer Res. 2015 Jan 15;75(2):446-55. doi: 10.1158/0008-5472.CAN-14-1223. Epub 2014 Nov 28.

18.

Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea.

Wu H, Chen M, Mao Y, Li W, Liu J, Huang X, Zhou Y, Ye BC, Zhang L, Weaver DT, Zhang B.

Microb Cell Fact. 2014 Nov 13;13:158. doi: 10.1186/s12934-014-0158-4.

19.

DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.

Seiwert TY, Wang X, Heitmann J, Villegas-Bergazzi V, Sprott K, Finn S, O'Regan E, Farrow AD, Weichselbaum RR, Lingen MW, Cohen EE, Stenson K, Weaver DT, Vokes EE.

PLoS One. 2014 Jul 14;9(7):e102112. doi: 10.1371/journal.pone.0102112. eCollection 2014.

20.

Use of telemedicine in retinopathy of prematurity.

Weaver DT.

Int Ophthalmol Clin. 2014 Summer;54(3):9-20. doi: 10.1097/IIO.0000000000000036. No abstract available.

PMID:
24879100
21.

Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship.

Shapiro IM, Kolev VN, Vidal CM, Kadariya Y, Ring JE, Wright Q, Weaver DT, Menges C, Padval M, McClatchey AI, Xu Q, Testa JR, Pachter JA.

Sci Transl Med. 2014 May 21;6(237):237ra68. doi: 10.1126/scitranslmed.3008639.

22.

SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea.

Wu P, Pan H, Zhang C, Wu H, Yuan L, Huang X, Zhou Y, Ye BC, Weaver DT, Zhang L, Zhang B.

J Ind Microbiol Biotechnol. 2014 Jul;41(7):1159-67. doi: 10.1007/s10295-014-1449-9. Epub 2014 May 3.

PMID:
24793123
23.

Telemedicine for retinopathy of prematurity.

Weaver DT.

Curr Opin Ophthalmol. 2013 Sep;24(5):425-31. doi: 10.1097/ICU.0b013e3283645b41. Review.

PMID:
23872819
24.

Management of a nasolacrimal duct fistula.

Guo S, Olitsky SE, Weaver DT.

J Pediatr Ophthalmol Strabismus. 2013 May-Jun;50(3):136-7. doi: 10.3928/01913913-20130419-01. No abstract available.

PMID:
23718936
25.

Review of thromboembolic prophylaxis in patients attending Cork University Hospital.

Byrne S, Weaver DT.

Int J Clin Pharm. 2013 Jun;35(3):439-46. doi: 10.1007/s11096-013-9760-5. Epub 2013 Mar 15.

PMID:
23494189
26.

Managing a case of hypotropia with a positive traction test.

Tien DR, Weaver DT.

J Pediatr Ophthalmol Strabismus. 2013 Jan-Feb;50(1):6-8. doi: 10.3928/01913913-20120720-01. No abstract available.

PMID:
23343087
27.

Telemedicine detection of type 1 ROP in a distant neonatal intensive care unit.

Weaver DT, Murdock TJ.

J AAPOS. 2012 Jun;16(3):229-33. doi: 10.1016/j.jaapos.2012.01.007.

PMID:
22681938
28.

Cisplatin benefit is predicted by immunohistochemical analysis of DNA repair proteins in squamous cell carcinoma but not adenocarcinoma: theranostic modeling by NSCLC constituent histological subclasses.

Pierceall WE, Olaussen KA, Rousseau V, Brambilla E, Sprott KM, Andre F, Pignon JP, Le Chevalier T, Pirker R, Jiang C, Filipits M, Chen Y, Kutok JL, Weaver DT, Ward BE, Soria JC.

Ann Oncol. 2012 Sep;23(9):2245-52. doi: 10.1093/annonc/mdr624. Epub 2012 Jan 23.

PMID:
22269178
29.

Preferred postoperative alignment in divergence excess intermittent exotropia.

Olitsky SE, Strominger MB, Weaver DT.

J Pediatr Ophthalmol Strabismus. 2012 Jan-Feb;49(1):5-7. doi: 10.3928/01913913-20110504-03. No abstract available.

PMID:
22268887
30.

Utilization of fluorescence in situ hybridization with cytokeratin discriminators in TOP2A assessment of chemotherapy-treated patients with breast cancer.

Pierceall WE, Sprott KM, Heikkinen T, Heikkila P, Alaparthi L, Aittomaki K, Al-Adhami M, Villegas-Bergazzi V, Meyer JL, Kutok JL, Bartkova J, Bartek J, Nevanlinna H, Weaver DT, Blomqvist C.

Hum Pathol. 2012 Sep;43(9):1363-75. doi: 10.1016/j.humpath.2011.08.018. Epub 2011 Dec 26.

PMID:
22204715
31.

DNA repair biomarkers predict response to neoadjuvant chemoradiotherapy in esophageal cancer.

Alexander BM, Wang XZ, Niemierko A, Weaver DT, Mak RH, Roof KS, Fidias P, Wain J, Choi NC.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):164-71. doi: 10.1016/j.ijrobp.2011.05.033. Epub 2011 Oct 12.

PMID:
22000749
32.

The ups and downs of DNA repair biomarkers for PARP inhibitor therapies.

Wang X, Weaver DT.

Am J Cancer Res. 2011;1(3):301-327. Epub 2010 Jan 3.

33.

XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck.

Vaezi A, Wang X, Buch S, Gooding W, Wang L, Seethala RR, Weaver DT, D'Andrea AD, Argiris A, Romkes M, Niedernhofer LJ, Grandis JR.

Clin Cancer Res. 2011 Aug 15;17(16):5513-22. doi: 10.1158/1078-0432.CCR-11-0086. Epub 2011 Jul 7.

34.

Strategies for H-score normalization of preanalytical technical variables with potential utility to immunohistochemical-based biomarker quantitation in therapeutic response diagnostics.

Pierceall WE, Wolfe M, Suschak J, Chang H, Chen Y, Sprott KM, Kutok JL, Quan S, Weaver DT, Ward BE.

Anal Cell Pathol (Amst). 2011;34(3):159-68. doi: 10.3233/ACP-2011-014.

35.

DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancer.

Alexander BM, Sprott K, Farrow DA, Wang X, D'Andrea AD, Schnitt SJ, Collins LC, Weaver DT, Garber JE.

Clin Cancer Res. 2010 Dec 1;16(23):5796-804. doi: 10.1158/1078-0432.CCR-10-0292.

36.

Treatment of a manifest strabismus with amblyopia.

Weaver DT, Burke MJ, Edmond JC.

J Pediatr Ophthalmol Strabismus. 2010 Jan-Feb;47(1):5-9. doi: 10.3928/01913913-20100106-01. No abstract available.

PMID:
20128545
37.

Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors.

Jin L, Pandey P, Babine RE, Weaver DT, Abdel-Meguid SS, Strickler JE.

Acta Crystallogr D Biol Crystallogr. 2005 Oct;61(Pt 10):1418-25. Epub 2005 Sep 28.

PMID:
16204896
38.

Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions.

Jin L, Pandey P, Babine RE, Gorga JC, Seidl KJ, Gelfand E, Weaver DT, Abdel-Meguid SS, Strickler JE.

J Biol Chem. 2005 Feb 11;280(6):4704-12. Epub 2004 Nov 15.

39.

The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors.

Jin L, Pluskey S, Petrella EC, Cantin SM, Gorga JC, Rynkiewicz MJ, Pandey P, Strickler JE, Babine RE, Weaver DT, Seidl KJ.

J Biol Chem. 2004 Oct 8;279(41):42818-25. Epub 2004 Jul 29.

40.

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Zhang J, Willers H, Feng Z, Ghosh JC, Kim S, Weaver DT, Chung JH, Powell SN, Xia F.

Mol Cell Biol. 2004 Jan;24(2):708-18.

41.

Interactions of the Nijmegen breakage syndrome protein with ATM and BRCA1.

Wu X, Rathbun G, Lane WS, Weaver DT, Livingston DM.

Cold Spring Harb Symp Quant Biol. 2000;65:535-45. Review. No abstract available.

PMID:
12760071
42.

Interaction of FANCD2 and NBS1 in the DNA damage response.

Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, Mathew CG, Kastan MB, Weaver DT, D'Andrea AD.

Nat Cell Biol. 2002 Dec;4(12):913-20.

PMID:
12447395
43.

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit.

Ranganathan V, Heine WF, Ciccone DN, Rudolph KL, Wu X, Chang S, Hai H, Ahearn IM, Livingston DM, Resnick I, Rosen F, Seemanova E, Jarolim P, DePinho RA, Weaver DT.

Curr Biol. 2001 Jun 26;11(12):962-6.

44.

Independence of R/M/N focus formation and the presence of intact BRCA1.

Wu X, Petrini JH, Heine WF, Weaver DT, Livingston DM, Chen J.

Science. 2000 Jul 7;289(5476):11. No abstract available.

45.

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response.

Wu X, Ranganathan V, Weisman DS, Heine WF, Ciccone DN, O'Neill TB, Crick KE, Pierce KA, Lane WS, Rathbun G, Livingston DM, Weaver DT.

Nature. 2000 May 25;405(6785):477-82.

PMID:
10839545
46.

Amniotic tissue in complete hydatidiform moles can be androgenetic.

Weaver DT, Fisher RA, Newlands ES, Paradinas FJ.

J Pathol. 2000 May;191(1):67-70.

PMID:
10767721
47.

Enforced CDK4 expression in a hematopoietic cell line confers resistance to the G1 arrest induced by ionizing radiation.

Reed MF, Liu VF, Ladha MH, Ando K, Griffin JD, Weaver DT, Ewen ME.

Oncogene. 1998 Dec 10;17(23):2961-71.

48.

DNA repair: bacteria to humans. A conference sponsored by the Genetics Society of America, April 16-19, 1998.

Weaver DT.

Biochim Biophys Acta. 1998 Oct 14;1378(2):R1-9. No abstract available.

PMID:
9823375
49.

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination.

Gao Y, Chaudhuri J, Zhu C, Davidson L, Weaver DT, Alt FW.

Immunity. 1998 Sep;9(3):367-76.

50.

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