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Items: 1 to 50 of 247

1.

Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial.

Townsend RR, Mahfoud F, Kandzari DE, Kario K, Pocock S, Weber MA, Ewen S, Tsioufis K, Tousoulis D, Sharp ASP, Watkinson AF, Schmieder RE, Schmid A, Choi JW, East C, Walton A, Hopper I, Cohen DL, Wilensky R, Lee DP, Ma A, Devireddy CM, Lea JP, Lurz PC, Fengler K, Davies J, Chapman N, Cohen SA, DeBruin V, Fahy M, Jones DE, Rothman M, Böhm M; SPYRAL HTN-OFF MED trial investigators*.

Lancet. 2017 Nov 11;390(10108):2160-2170. doi: 10.1016/S0140-6736(17)32281-X. Epub 2017 Aug 28.

PMID:
28859944
2.

Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial.

Meyer T, Fox R, Ma YT, Ross PJ, James MW, Sturgess R, Stubbs C, Stocken DD, Wall L, Watkinson A, Hacking N, Evans TRJ, Collins P, Hubner RA, Cunningham D, Primrose JN, Johnson PJ, Palmer DH.

Lancet Gastroenterol Hepatol. 2017 Aug;2(8):565-575. doi: 10.1016/S2468-1253(17)30156-5. Epub 2017 Jun 23.

3.

Amplatzer Vascular Plug 4 Insertion for the Treatment of a Left Subclavian Artery Pseudoaneurysm.

Shaygi B, Kinsella D, Watkinson AF.

Ann Vasc Surg. 2017 Aug;43:311.e5-311.e7. doi: 10.1016/j.avsg.2017.02.011. Epub 2017 May 4.

PMID:
28478167
4.

Beliefs About Pharmaceutical Medicines and Natural Remedies Explain Individual Variation in Placebo Analgesia.

Watkinson A, Chapman SCE, Horne R.

J Pain. 2017 Aug;18(8):908-922. doi: 10.1016/j.jpain.2017.02.435. Epub 2017 Mar 7.

PMID:
28279704
5.

Recombinant anthrax protective antigen: Observation of aggregation phenomena by TEM reveals specific effects of sterols.

Harris JR, Soliakov A, Watkinson A, Lakey JH.

Micron. 2017 Feb;93:1-8. doi: 10.1016/j.micron.2016.10.007. Epub 2016 Nov 15.

PMID:
27883989
6.

Standardised survey method for identifying catchment risks to water quality.

Baker DL, Ferguson CM, Chier P, Warnecke M, Watkinson A.

J Water Health. 2016 Jun;14(3):349-68. doi: 10.2166/wh.2015.054.

PMID:
27280603
7.

Lone Stent-Graft Treatment of Symptomatic Gluteal Artery Aneurysm.

Western CE, Stasinou T, Kinsella D, Guinness R, Watkinson A, Thompson JF.

Ann Vasc Surg. 2016 Aug;35:205.e1-4. doi: 10.1016/j.avsg.2016.01.038. Epub 2016 May 26.

PMID:
27238983
8.

Future of the transdermal drug delivery market--have we barely touched the surface?

Watkinson AC, Kearney MC, Quinn HL, Courtenay AJ, Donnelly RF.

Expert Opin Drug Deliv. 2016;13(4):523-32. doi: 10.1517/17425247.2016.1130034. Epub 2015 Dec 28. Review.

PMID:
26646399
9.

Determining the probability of cyanobacterial blooms: the application of Bayesian networks in multiple lake systems.

Rigosi A, Hanson P, Hamilton DP, Hipsey M, Rusak JA, Bois J, Sparber K, Chorus I, Watkinson AJ, Qin B, Kim B, Brookes JD.

Ecol Appl. 2015 Jan;25(1):186-99.

PMID:
26255367
10.

Conserving tropical biodiversity via market forces and spatial targeting.

Bateman IJ, Coombes E, Fitzherbert E, Binner A, Bad'ura T, Carbone C, Fisher B, Naidoo R, Watkinson AR.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7408-13. doi: 10.1073/pnas.1406484112.

11.

A global database of lake surface temperatures collected by in situ and satellite methods from 1985-2009.

Sharma S, Gray DK, Read JS, O'Reilly CM, Schneider P, Qudrat A, Gries C, Stefanoff S, Hampton SE, Hook S, Lenters JD, Livingstone DM, McIntyre PB, Adrian R, Allan MG, Anneville O, Arvola L, Austin J, Bailey J, Baron JS, Brookes J, Chen Y, Daly R, Dokulil M, Dong B, Ewing K, de Eyto E, Hamilton D, Havens K, Haydon S, Hetzenauer H, Heneberry J, Hetherington AL, Higgins SN, Hixson E, Izmest'eva LR, Jones BM, Kangur K, Kasprzak P, Köster O, Kraemer BM, Kumagai M, Kuusisto E, Leshkevich G, May L, MacIntyre S, Müller-Navarra D, Naumenko M, Noges P, Noges T, Niederhauser P, North RP, Paterson AM, Plisnier PD, Rigosi A, Rimmer A, Rogora M, Rudstam L, Rusak JA, Salmaso N, Samal NR, Schindler DE, Schladow G, Schmidt SR, Schultz T, Silow EA, Straile D, Teubner K, Verburg P, Voutilainen A, Watkinson A, Weyhenmeyer GA, Williamson CE, Woo KH.

Sci Data. 2015 Mar 17;2:150008. doi: 10.1038/sdata.2015.8. eCollection 2015.

12.

Cattle-derived microbial input to source water catchments: An experimental assessment of stream crossing modification.

Smolders A, Rolls RJ, Ryder D, Watkinson A, Mackenzie M.

J Environ Manage. 2015 Jun 1;156:143-9. doi: 10.1016/j.jenvman.2015.03.052. Epub 2015 Apr 2.

PMID:
25841195
13.

Identifying the science and technology dimensions of emerging public policy issues through horizon scanning.

Parker M, Acland A, Armstrong HJ, Bellingham JR, Bland J, Bodmer HC, Burall S, Castell S, Chilvers J, Cleevely DD, Cope D, Costanzo L, Dolan JA, Doubleday R, Feng WY, Godfray HC, Good DA, Grant J, Green N, Groen AJ, Guilliams TT, Gupta S, Hall AC, Heathfield A, Hotopp U, Kass G, Leeder T, Lickorish FA, Lueshi LM, Magee C, Mata T, McBride T, McCarthy N, Mercer A, Neilson R, Ouchikh J, Oughton EJ, Oxenham D, Pallett H, Palmer J, Patmore J, Petts J, Pinkerton J, Ploszek R, Pratt A, Rocks SA, Stansfield N, Surkovic E, Tyler CP, Watkinson AR, Wentworth J, Willis R, Wollner PK, Worts K, Sutherland WJ.

PLoS One. 2014 May 30;9(5):e96480. doi: 10.1371/journal.pone.0096480. eCollection 2014.

14.

The effect of formulation excipients on the penetration and lateral diffusion of ibuprofen on and within the stratum corneum following topical application to humans.

Gee CM, Watkinson AC, Nicolazzo JA, Finnin BC.

J Pharm Sci. 2014 Mar;103(3):909-19. doi: 10.1002/jps.23850. Epub 2014 Jan 13.

PMID:
24421242
15.

A horizon scan of global conservation issues for 2014.

Sutherland WJ, Aveling R, Brooks TM, Clout M, Dicks LV, Fellman L, Fleishman E, Gibbons DW, Keim B, Lickorish F, Monk KA, Mortimer D, Peck LS, Pretty J, Rockström J, Rodríguez JP, Smith RK, Spalding MD, Tonneijck FH, Watkinson AR.

Trends Ecol Evol. 2014 Jan;29(1):15-22. doi: 10.1016/j.tree.2013.11.004. Epub 2013 Dec 11. Review.

16.

Long-term clinical and functional outcome following treatment for Paget-Schroetter syndrome.

Taylor JM, Telford RJ, Kinsella DC, Watkinson AF, Thompson JF.

Br J Surg. 2013 Oct;100(11):1459-64. doi: 10.1002/bjs.9279.

PMID:
24037565
17.

Increasing the potency of an alhydrogel-formulated anthrax vaccine by minimizing antigen-adjuvant interactions.

Watkinson A, Soliakov A, Ganesan A, Hirst K, Lebutt C, Fleetwood K, Fusco PC, Fuerst TR, Lakey JH.

Clin Vaccine Immunol. 2013 Nov;20(11):1659-68. doi: 10.1128/CVI.00320-13. Epub 2013 Aug 28.

18.

Modelling skin penetration using the Laplace transform technique.

Anissimov YG, Watkinson A.

Skin Pharmacol Physiol. 2013;26(4-6):286-94. doi: 10.1159/000351924. Epub 2013 Jul 29.

PMID:
23921115
19.

Nanoparticles do not penetrate human skin--a theoretical perspective.

Watkinson AC, Bunge AL, Hadgraft J, Lane ME.

Pharm Res. 2013 Aug;30(8):1943-6. doi: 10.1007/s11095-013-1073-9. Epub 2013 May 31.

PMID:
23722409
20.

A commentary on transdermal drug delivery systems in clinical trials.

Watkinson AC.

J Pharm Sci. 2013 Sep;102(9):3082-8. doi: 10.1002/jps.23490. Epub 2013 Mar 6.

PMID:
23468246
21.

A horizon scan of global conservation issues for 2013.

Sutherland WJ, Bardsley S, Clout M, Depledge MH, Dicks LV, Fellman L, Fleishman E, Gibbons DW, Keim B, Lickorish F, Margerison C, Monk KA, Norris K, Peck LS, Prior SV, Scharlemann JP, Spalding MD, Watkinson AR.

Trends Ecol Evol. 2013 Jan;28(1):16-22. doi: 10.1016/j.tree.2012.10.022. Epub 2012 Dec 7.

PMID:
23219597
22.

Influence of penetration enhancer on drug permeation from volatile formulations.

Santos P, Watkinson AC, Hadgraft J, Lane ME.

Int J Pharm. 2012 Dec 15;439(1-2):260-8. doi: 10.1016/j.ijpharm.2012.09.031. Epub 2012 Sep 20.

PMID:
23000063
23.

Predicting skin penetration of actives from complex cosmetic formulations: an evaluation of inter formulation and inter active effects during formulation optimization for transdermal delivery.

Wiechers JW, Watkinson AC, Cross SE, Roberts MS.

Int J Cosmet Sci. 2012 Dec;34(6):525-35. doi: 10.1111/ics.12001. Epub 2012 Oct 11.

PMID:
22950455
24.

Biophysical characterisation of thermal-induced precipitates of recombinant anthrax protective antigen: evidence for kinetically trapped unfolding domains in solid-state.

Ganesan A, Watkinson A, Moore BD.

Eur J Pharm Biopharm. 2012 Nov;82(3):475-84. doi: 10.1016/j.ejpb.2012.05.019. Epub 2012 Jun 7.

PMID:
22683695
25.

Assessment of the lateral diffusion and penetration of topically applied drugs in humans using a novel concentric tape stripping design.

Gee CM, Nicolazzo JA, Watkinson AC, Finnin BC.

Pharm Res. 2012 Aug;29(8):2035-46. doi: 10.1007/s11095-012-0731-7. Epub 2012 Mar 16.

PMID:
22422320
26.

A horizon scan of global conservation issues for 2012.

Sutherland WJ, Aveling R, Bennun L, Chapman E, Clout M, Côté IM, Depledge MH, Dicks LV, Dobson AP, Fellman L, Fleishman E, Gibbons DW, Keim B, Lickorish F, Lindenmayer DB, Monk KA, Norris K, Peck LS, Prior SV, Scharlemann JP, Spalding M, Watkinson AR.

Trends Ecol Evol. 2012 Jan;27(1):12-18. doi: 10.1016/j.tree.2011.10.011. Epub 2011 Nov 29.

PMID:
22133790
27.

Variant obturator artery complicating uterine artery embolization.

Nair SB, Sidhu HS, Watkinson AF.

Clin Radiol. 2012 Mar;67(3):290-1. doi: 10.1016/j.crad.2011.09.006. Epub 2011 Nov 12. No abstract available.

PMID:
22079486
28.

Transcatheter treatment of hepatocellular carcinoma with Doxorubicin-loaded DC Bead (DEBDOX): technical recommendations.

Lencioni R, de Baere T, Burrel M, Caridi JG, Lammer J, Malagari K, Martin RC, O'Grady E, Real MI, Vogl TJ, Watkinson A, Geschwind JF.

Cardiovasc Intervent Radiol. 2012 Oct;35(5):980-5. Epub 2011 Oct 19. Review.

29.

Anthrax sub-unit vaccine: the structural consequences of binding rPA83 to Alhydrogel®.

Soliakov A, Kelly IF, Lakey JH, Watkinson A.

Eur J Pharm Biopharm. 2012 Jan;80(1):25-32. doi: 10.1016/j.ejpb.2011.09.009. Epub 2011 Sep 22.

30.

Liver, gastrointestinal, and cardiac toxicity in intermediate hepatocellular carcinoma treated with PRECISION TACE with drug-eluting beads: results from the PRECISION V randomized trial.

Vogl TJ, Lammer J, Lencioni R, Malagari K, Watkinson A, Pilleul F, Denys A, Lee C.

AJR Am J Roentgenol. 2011 Oct;197(4):W562-70. doi: 10.2214/AJR.10.4379.

PMID:
21940527
31.

Coral identity underpins architectural complexity on Caribbean reefs.

Alvarez-Filip L, Dulvy NK, Côte IM, Watkinson AR, Gill JA.

Ecol Appl. 2011 Sep;21(6):2223-31.

PMID:
21939056
32.

Alhydrogel® adjuvant, ultrasonic dispersion and protein binding: a TEM and analytical study.

Harris JR, Soliakov A, Lewis RJ, Depoix F, Watkinson A, Lakey JH.

Micron. 2012 Feb;43(2-3):192-200. doi: 10.1016/j.micron.2011.07.012. Epub 2011 Jul 27.

PMID:
21831642
33.

Formulation issues associated with transdermal fentanyl delivery.

Santos P, Watkinson AC, Hadgraft J, Lane ME.

Int J Pharm. 2011 Sep 15;416(1):155-9. doi: 10.1016/j.ijpharm.2011.06.024. Epub 2011 Jun 23.

PMID:
21723931
34.

Efficacy and safety of the 2% formulation of testosterone topical solution applied to the axillae in androgen-deficient men.

Wang C, Ilani N, Arver S, McLachlan RI, Soulis T, Watkinson A.

Clin Endocrinol (Oxf). 2011 Dec;75(6):836-43. doi: 10.1111/j.1365-2265.2011.04152.x.

PMID:
21689131
35.

Venous thoracic outlet compression and the Paget-Schroetter syndrome: a review and recommendations for management.

Thompson JF, Winterborn RJ, Bays S, White H, Kinsella DC, Watkinson AF.

Cardiovasc Intervent Radiol. 2011 Oct;34(5):903-10. doi: 10.1007/s00270-011-0148-4. Epub 2011 Mar 30. Review.

PMID:
21448772
36.

Pre-uterine artery embolization MRI: beyond fibroids.

Williams PL, Coote JM, Watkinson AF.

Cardiovasc Intervent Radiol. 2011 Dec;34(6):1143-50. doi: 10.1007/s00270-011-0124-z. Epub 2011 Feb 18. Review.

PMID:
21331454
37.

Enhanced permeation of fentanyl from supersaturated solutions in a model membrane.

Santos P, Watkinson AC, Hadgraft J, Lane ME.

Int J Pharm. 2011 Apr 4;407(1-2):72-7. doi: 10.1016/j.ijpharm.2011.01.025. Epub 2011 Jan 21.

PMID:
21256946
38.

The occurrence of the herbicide dalapon (2,2-dichloropropionate) in potable water as a disinfection by-product.

Hawker DW, Cumming JL, Watkinson A, Bartkow ME.

J Environ Monit. 2011 Feb;13(2):252-6. doi: 10.1039/c0em00475h. Epub 2010 Dec 17.

PMID:
21165509
39.

Horizon scan of global conservation issues for 2011.

Sutherland WJ, Bardsley S, Bennun L, Clout M, Côté IM, Depledge MH, Dicks LV, Dobson AP, Fellman L, Fleishman E, Gibbons DW, Impey AJ, Lawton JH, Lickorish F, Lindenmayer DB, Lovejoy TE, Nally RM, Madgwick J, Peck LS, Pretty J, Prior SV, Redford KH, Scharlemann JP, Spalding M, Watkinson AR.

Trends Ecol Evol. 2011 Jan;26(1):10-6. doi: 10.1016/j.tree.2010.11.002. Epub 2010 Dec 2. Review.

PMID:
21126797
40.

Density-structured models for plant population dynamics.

Freckleton RP, Sutherland WJ, Watkinson AR, Queenborough SA.

Am Nat. 2011 Jan;177(1):1-17. doi: 10.1086/657621. Epub 2010 Dec 2.

PMID:
21126176
41.

Use of an endovascular stent graft and percutaneous thrombin injection to treat an iatrogenic hepatic artery pseudoaneurysm.

Boddy A, Macanovic M, Thompson J, Watkinson A.

Ann R Coll Surg Engl. 2010 Oct 15. [Epub ahead of print]

PMID:
20955656
42.

The structure of Yersinia pestis Caf1 polymer in free and adjuvant bound states.

Soliakov A, Harris JR, Watkinson A, Lakey JH.

Vaccine. 2010 Aug 9;28(35):5746-54. doi: 10.1016/j.vaccine.2010.05.074. Epub 2010 Jun 18.

PMID:
20600492
43.

Transhepatic assisted transoral placement of a duodenal stent in malignant gastric outlet obstruction.

Milson A, Abdellaoui A, Fraser C, Watkinson AF.

J Vasc Interv Radiol. 2010 Apr;21(4):590-2. doi: 10.1016/j.jvir.2009.12.386. Epub 2010 Feb 9.

PMID:
20149689
44.

A horizon scan of global conservation issues for 2010.

Sutherland WJ, Clout M, Côté IM, Daszak P, Depledge MH, Fellman L, Fleishman E, Garthwaite R, Gibbons DW, De Lurio J, Impey AJ, Lickorish F, Lindenmayer D, Madgwick J, Margerison C, Maynard T, Peck LS, Pretty J, Prior S, Redford KH, Scharlemann JP, Spalding M, Watkinson AR.

Trends Ecol Evol. 2010 Jan;25(1):1-7. doi: 10.1016/j.tree.2009.10.003. Epub 2009 Nov 26.

PMID:
19939492
45.

Glue ablation of a late-presentation urinary fistula after partial nephrectomy.

Aning JJ, Stott MA, Watkinson AF.

Br J Radiol. 2009 Dec;82(984):e246-8. doi: 10.1259/bjr/93776392.

46.

Prospective randomized study of doxorubicin-eluting-bead embolization in the treatment of hepatocellular carcinoma: results of the PRECISION V study.

Lammer J, Malagari K, Vogl T, Pilleul F, Denys A, Watkinson A, Pitton M, Sergent G, Pfammatter T, Terraz S, Benhamou Y, Avajon Y, Gruenberger T, Pomoni M, Langenberger H, Schuchmann M, Dumortier J, Mueller C, Chevallier P, Lencioni R; PRECISION V Investigators.

Cardiovasc Intervent Radiol. 2010 Feb;33(1):41-52. doi: 10.1007/s00270-009-9711-7. Epub 2009 Nov 12.

47.

Oxybutynin permeation in skin: the influence of drug and solvent activity.

Santos P, Watkinson AC, Hadgraft J, Lane ME.

Int J Pharm. 2010 Jan 15;384(1-2):67-72. doi: 10.1016/j.ijpharm.2009.09.043. Epub 2009 Sep 30.

PMID:
19799975
48.

Flattening of Caribbean coral reefs: region-wide declines in architectural complexity.

Alvarez-Filip L, Dulvy NK, Gill JA, Côté IM, Watkinson AR.

Proc Biol Sci. 2009 Aug 22;276(1669):3019-25. doi: 10.1098/rspb.2009.0339. Epub 2009 Jun 10.

49.

Unwell man with abdominal pain.

Currie RJ, Watkinson A.

BMJ. 2009 May 13;338:b1635. doi: 10.1136/bmj.b1635. No abstract available.

PMID:
19439768
50.

The effect of drug concentration on solvent activity in silicone membranes.

Santos P, Machado M, Watkinson AC, Hadgraft J, Lane ME.

Int J Pharm. 2009 Jul 30;377(1-2):70-5. doi: 10.1016/j.ijpharm.2009.05.002. Epub 2009 May 9.

PMID:
19439167

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