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Corticosteroid use endpoints in neuro-oncology: Response Assessment in Neuro-Oncology Working Group.

Arvold ND, Armstrong TS, Warren KE, Chang SM, DeAngelis LM, Blakeley J, Chamberlain MC, Dunbar E, Loong HH, Macdonald DR, Reardon DA, Vogelbaum MA, Yuan Y, Weller M, van den Bent M, Wen PY.

Neuro Oncol. 2018 May 18. doi: 10.1093/neuonc/noy056. [Epub ahead of print]


Time-to-event Bayesian Optimal Interval Design to Accelerate Phase I Trials.

Yuan Y, Lin R, Li D, Nie L, Warren KE.

Clin Cancer Res. 2018 May 16. pii: clincanres.0246.2018. doi: 10.1158/1078-0432.CCR-18-0246. [Epub ahead of print]


Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

Hoffman LM, Veldhuijzen van Zanten SEM, Colditz N, Baugh J, Chaney B, Hoffmann M, Lane A, Fuller C, Miles L, Hawkins C, Bartels U, Bouffet E, Goldman S, Leary S, Foreman NK, Packer R, Warren KE, Broniscer A, Kieran MW, Minturn J, Comito M, Broxson E, Shih CS, Khatua S, Chintagumpala M, Carret AS, Escorza NY, Hassall T, Ziegler DS, Gottardo N, Dholaria H, Doughman R, Benesch M, Drissi R, Nazarian J, Jabado N, Boddaert N, Varlet P, Giraud G, Castel D, Puget S, Jones C, Hulleman E, Modena P, Giagnacovo M, Antonelli M, Pietsch T, Gielen GH, Jones DTW, Sturm D, Pfister SM, Gerber NU, Grotzer MA, Pfaff E, von Bueren AO, Hargrave D, Solanki GA, Jadrijevic Cvrlje F, Kaspers GJL, Vandertop WP, Grill J, Bailey S, Biassoni V, Massimino M, Calmon R, Sanchez E, Bison B, Warmuth-Metz M, Leach J, Jones B, van Vuurden DG, Kramm CM, Fouladi M.

J Clin Oncol. 2018 May 10:JCO2017759308. doi: 10.1200/JCO.2017.75.9308. [Epub ahead of print]


Durable regression of Medulloblastoma after regional and intravenous delivery of anti-HER2 chimeric antigen receptor T cells.

Nellan A, Rota C, Majzner R, Lester-McCully CM, Griesinger AM, Mulcahy Levy JM, Foreman NK, Warren KE, Lee DW.

J Immunother Cancer. 2018 Apr 30;6(1):30. doi: 10.1186/s40425-018-0340-z.


Response to Harreld re: "Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology Committee".

Warren KE, Vezina G, Poussaint TY, Warmuth-Metz M, Packer RJ, Kieran MW.

Neuro Oncol. 2018 Jan 10;20(1):144-145. doi: 10.1093/neuonc/nox219. No abstract available.


Spontaneously regressing brain lesions in Smith-Lemli-Opitz syndrome.

Dang Do AN, Baker EH, Warren KE, Bianconi SE, Porter FD.

Am J Med Genet A. 2018 Feb;176(2):386-390. doi: 10.1002/ajmg.a.38563. Epub 2017 Dec 11.


Combatting the opioid epidemic: Baltimore's experience and lessons learned.

Wen LS, Warren KE.

J Public Health (Oxf). 2017 Jul 19:1-5. doi: 10.1093/pubmed/fdx093. [Epub ahead of print]


Gliomatosis Cerebri: Current Understanding and Controversies.

Ranjan S, Warren KE.

Front Oncol. 2017 Aug 7;7:165. doi: 10.3389/fonc.2017.00165. eCollection 2017. Review.


Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study.

Cooney T, Lane A, Bartels U, Bouffet E, Goldman S, Leary SES, Foreman NK, Packer RJ, Broniscer A, Minturn JE, Shih CS, Chintagumpala M, Hassall T, Gottardo NG, Dholaria H, Hoffman L, Chaney B, Baugh J, Doughman R, Leach JL, Jones BV, Fouladi M, Warren KE, Monje M.

Neuro Oncol. 2017 Sep 1;19(9):1279-1280. doi: 10.1093/neuonc/nox107. No abstract available.


The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma.

Miyahara H, Yadavilli S, Natsumeda M, Rubens JA, Rodgers L, Kambhampati M, Taylor IC, Kaur H, Asnaghi L, Eberhart CG, Warren KE, Nazarian J, Raabe EH.

Cancer Lett. 2017 Aug 1;400:110-116. doi: 10.1016/j.canlet.2017.04.019. Epub 2017 Apr 25.


Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology committee.

Warren KE, Vezina G, Poussaint TY, Warmuth-Metz M, Chamberlain MC, Packer RJ, Brandes AA, Reiss M, Goldman S, Fisher MJ, Pollack IF, Prados MD, Wen PY, Chang SM, Dufour C, Zurakowski D, Kortmann RD, Kieran MW.

Neuro Oncol. 2018 Jan 10;20(1):13-23. doi: 10.1093/neuonc/nox087.


The Role of Public Health in Combatting Synthetic Cannabinoid Use in Adolescents.

Warren KE, Tay S, Wen LS.

J Adolesc Health. 2017 May;60(5):483-486. doi: 10.1016/j.jadohealth.2017.02.015.


Plasma and cerebrospinal fluid pharmacokinetics of select chemotherapeutic agents following intranasal delivery in a non-human primate model.

League-Pascual JC, Lester-McCully CM, Shandilya S, Ronner L, Rodgers L, Cruz R, Peer CJ, Figg WD, Warren KE.

J Neurooncol. 2017 May;132(3):401-407. doi: 10.1007/s11060-017-2388-x. Epub 2017 Mar 13.


The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease.

Baugh J, Bartels U, Leach J, Jones B, Chaney B, Warren KE, Kirkendall J, Doughman R, Hawkins C, Miles L, Fuller C, Hassall T, Bouffet E, Lane A, Hargrave D, Grill J, Hoffman LM, Jones C, Towbin A, Savage SA, Monje M, Li XN, Ziegler DS, Veldhuijzen van Zanten S, Kramm CM, van Vuurden DG, Fouladi M.

J Neurooncol. 2017 Apr;132(2):323-331. doi: 10.1007/s11060-017-2372-5. Epub 2017 Jan 16.


The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.

Pajtler KW, Mack SC, Ramaswamy V, Smith CA, Witt H, Smith A, Hansford JR, von Hoff K, Wright KD, Hwang E, Frappaz D, Kanemura Y, Massimino M, Faure-Conter C, Modena P, Tabori U, Warren KE, Holland EC, Ichimura K, Giangaspero F, Castel D, von Deimling A, Kool M, Dirks PB, Grundy RG, Foreman NK, Gajjar A, Korshunov A, Finlay J, Gilbertson RJ, Ellison DW, Aldape KD, Merchant TE, Bouffet E, Pfister SM, Taylor MD.

Acta Neuropathol. 2017 Jan;133(1):5-12. doi: 10.1007/s00401-016-1643-0. Epub 2016 Nov 17.


Minimally Invasive Lumbar Port System for the Collection of Cerebrospinal Fluid from Rhesus Macaques (Macaca mulatta).

MacAllister RP, Lester McCully CM, Bacher J, Thomas ML III, Cruz R, Wangari S, Warren KE.

Comp Med. 2016;66(4):349-52.


Measles, social media and surveillance in Baltimore City.

Warren KE, Wen LS.

J Public Health (Oxf). 2017 Sep 1;39(3):e73-e78. doi: 10.1093/pubmed/fdw076.


Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours.

Nailor A, Walker DA, Jacques TS, Warren KE, Brem H, Kearns PR, Greenwood J, Penny JI, Pilkington GJ, Carcaboso AM, Fleischhack G, Macarthur D, Slavc I, Meijer L, Gill S, Lowis S, van Vuurden DG, Pearl MS, Clifford SC, Morrissy S, Ivanov DP, Beccaria K, Gilbertson RJ, Straathof K, Green JJ, Smith S, Rahman R, Kilday JP.

Ecancermedicalscience. 2016 Mar 31;10:630. doi: 10.3332/ecancer.2016.630. eCollection 2016.


Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.

Nikbakht H, Panditharatna E, Mikael LG, Li R, Gayden T, Osmond M, Ho CY, Kambhampati M, Hwang EI, Faury D, Siu A, Papillon-Cavanagh S, Bechet D, Ligon KL, Ellezam B, Ingram WJ, Stinson C, Moore AS, Warren KE, Karamchandani J, Packer RJ, Jabado N, Majewski J, Nazarian J.

Nat Commun. 2016 Apr 6;7:11185. doi: 10.1038/ncomms11185.


Patient and Public Risks of Powdered Alcohol: A Citywide Case Study to Prevent Abuse.

Warren KE, Tay S, Wen LS.

Ann Intern Med. 2016 May 17;164(10):685-6. doi: 10.7326/M15-2291. Epub 2016 Feb 16. No abstract available.


The Postcard Initiative: Personal Communication From Students Can Increase Timely Compliance With Health Requirements.

Maurer M, Warren KE, Pohl C.

NASN Sch Nurse. 2016 May;31(3):147-9. doi: 10.1177/1942602X15619757. Epub 2016 Jan 28.


Baltimore's Unrest: Perspectives From Public Health and Emergency Physician Leaders.

Khaldun JS, Warren KE, Wen LS.

Disaster Med Public Health Prep. 2016 Apr;10(2):293-5. doi: 10.1017/dmp.2015.170. Epub 2015 Dec 22.


Plasma and cerebrospinal fluid pharmacokinetics of vincristine and vincristine sulfate liposomes injection (VSLI, marqibo®) after intravenous administration in Non-human primates.

Shah NN, Cole DE, Lester-McCully CM, Wayne AS, Warren KE, Widemann BC.

Invest New Drugs. 2016 Feb;34(1):61-5. doi: 10.1007/s10637-015-0311-x. Epub 2015 Dec 10.


Public Health in the Unrest: Baltimore's Preparedness and Response After Freddie Gray's Death.

Wen LS, Warren KE, Tay S, Khaldun JS, O'Neill DL, Farrow OD.

Am J Public Health. 2015 Oct;105(10):1957-9. doi: 10.2105/AJPH.2015.302838. Epub 2015 Aug 13. No abstract available.


Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M.

Nat Med. 2015 Jul;21(7):827. doi: 10.1038/nm0715-827a. No abstract available.


Disrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain Inhibition.

Taylor IC, Hütt-Cabezas M, Brandt WD, Kambhampati M, Nazarian J, Chang HT, Warren KE, Eberhart CG, Raabe EH.

J Neuropathol Exp Neurol. 2015 Aug;74(8):778-90. doi: 10.1097/NEN.0000000000000216.


Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M.

Nat Med. 2015 Jun;21(6):555-9. doi: 10.1038/nm.3855. Epub 2015 May 4. Erratum in: Nat Med. 2015 Jul;21(7):827.


Plasma and cerebrospinal fluid pharmacokinetics of the Akt inhibitor, perifosine, in a non-human primate model.

Cole DE, Lester-McCully CM, Widemann BC, Warren KE.

Cancer Chemother Pharmacol. 2015 May;75(5):923-8. doi: 10.1007/s00280-015-2711-1. Epub 2015 Mar 5.


Development of a cerebrospinal fluid lateral reservoir model in rhesus monkeys (Macaca mulatta).

Lester McCully CM, Bacher J, MacAllister RP, Steffen-Smith EA, Saleem K, Thomas ML 3rd, Cruz R, Warren KE.

Comp Med. 2015 Feb;65(1):77-82.


Phase 1 trial and pharmacokinetic study of the oral platinum analog satraplatin in children and young adults with refractory solid tumors including brain tumors.

Akshintala S, Marcus L, Warren KE, Murphy RF, Sissung TM, Srivastava A, Goodspeed WJ, Goodwin A, Brewer CC, Zalewski C, King KA, Kim A, Figg WD, Widemann BC.

Pediatr Blood Cancer. 2015 Apr;62(4):603-10. doi: 10.1002/pbc.25344. Epub 2015 Jan 3.


Measuring the pons: a non-invasive biomarker for pediatric diffuse intrinsic pontine glioma.

Warren KE.

CNS Oncol. 2014 May;3(3):181-3. doi: 10.2217/cns.14.10. No abstract available.


Diffusion tensor histogram analysis of pediatric diffuse intrinsic pontine glioma.

Steffen-Smith EA, Sarlls JE, Pierpaoli C, Shih JH, Bent RS, Walker L, Warren KE.

Biomed Res Int. 2014;2014:647356. doi: 10.1155/2014/647356. Epub 2014 Jun 11.


A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a pediatric brain tumor consortium report.

Su JM, Thompson P, Adesina A, Li XN, Kilburn L, Onar-Thomas A, Kocak M, Chyla B, McKeegan E, Warren KE, Goldman S, Pollack IF, Fouladi M, Chen A, Giranda V, Boyett J, Kun L, Blaney SM.

Neuro Oncol. 2014 Dec;16(12):1661-8. doi: 10.1093/neuonc/nou103. Epub 2014 Jun 7.


Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma.

Ahsan S, Raabe EH, Haffner MC, Vaghasia A, Warren KE, Quezado M, Ballester LY, Nazarian J, Eberhart CG, Rodriguez FJ.

Acta Neuropathol Commun. 2014 Jun 3;2:59. doi: 10.1186/2051-5960-2-59.


Magnetic resonance imaging properties of convective delivery in diffuse intrinsic pontine gliomas.

Chittiboina P, Heiss JD, Warren KE, Lonser RR.

J Neurosurg Pediatr. 2014 Mar;13(3):276-82. doi: 10.3171/2013.11.PEDS136. Epub 2014 Jan 10.


What do parents want to know when considering autopsy for their child with cancer?

Wiener L, Sweeney C, Baird K, Merchant MS, Warren KE, Corner GW, Roberts KE, Lichtenthal WG.

J Pediatr Hematol Oncol. 2014 Aug;36(6):464-70. doi: 10.1097/MPH.0000000000000078.


Model for concomitant microdialysis sampling of the pons and cerebral cortex in rhesus macaques (Macaca mulatta).

McCully CM, Pastakia D, Bacher J, Thomas ML 3rd, Steffen-Smith EA, Saleem K, Murphy RF, Walbridge S, Brinster L, Widemann BC, Warren KE.

Comp Med. 2013 Aug;63(4):355-60.


Measurements of the pons as a biomarker of progression for pediatric DIPG.

Steffen-Smith EA, Baker EH, Venzon D, Shandilya S, Bent RS, Warren KE.

J Neurooncol. 2014 Jan;116(1):127-33. doi: 10.1007/s11060-013-1266-4. Epub 2013 Oct 10.


Bevacizumab (BVZ)-associated toxicities in children with recurrent central nervous system tumors treated with BVZ and irinotecan (CPT-11): a Pediatric Brain Tumor Consortium Study (PBTC-022).

Fangusaro J, Gururangan S, Poussaint TY, McLendon RE, Onar-Thomas A, Warren KE, Wu S, Packer RJ, Banerjee A, Gilbertson RJ, Jakacki R, Gajjar A, Goldman S, Pollack IF, Friedman HS, Boyett JM, Kun LE, Fouladi M.

Cancer. 2013 Dec 1;119(23):4180-7. doi: 10.1002/cncr.28343. Epub 2013 Sep 19.


Challenges with defining response to antitumor agents in pediatric neuro-oncology: a report from the response assessment in pediatric neuro-oncology (RAPNO) working group.

Warren KE, Poussaint TY, Vezina G, Hargrave D, Packer RJ, Goldman S, Wen PY, Pollack IF, Zurakowski D, Kun LE, Prados MD, Rutkowski S, Kieran MW.

Pediatr Blood Cancer. 2013 Sep;60(9):1397-401. doi: 10.1002/pbc.24562. Epub 2013 Apr 26.


Unclear standard of care for pediatric high grade glioma patients.

Fangusaro J, Warren KE.

J Neurooncol. 2013 Jun;113(2):341-2. doi: 10.1007/s11060-013-1104-8. Epub 2013 Mar 8. No abstract available.


Diffuse intrinsic pontine glioma: poised for progress.

Warren KE.

Front Oncol. 2012 Dec 28;2:205. doi: 10.3389/fonc.2012.00205. eCollection 2012.


Pediatric high-grade gliomas: survival at what cost?

Warren KE.

Transl Pediatr. 2012 Oct;1(2):116-7. doi: 10.3978/j.issn.2224-4336.2012.09.01. No abstract available.


Molecular imaging of pediatric brain tumors: comparison of tumor metabolism using ¹⁸F-FDG-PET and MRSI.

Hipp SJ, Steffen-Smith EA, Patronas N, Herscovitch P, Solomon JM, Bent RS, Steinberg SM, Warren KE.

J Neurooncol. 2012 Sep;109(3):521-7. doi: 10.1007/s11060-012-0918-0. Epub 2012 Jul 4.


Single- and multivoxel proton spectroscopy in pediatric patients with diffuse intrinsic pontine glioma.

Steffen-Smith EA, Venzon DJ, Bent RS, Hipp SJ, Warren KE.

Int J Radiat Oncol Biol Phys. 2012 Nov 1;84(3):774-9. doi: 10.1016/j.ijrobp.2012.01.032. Epub 2012 Mar 23.


Role of early postradiation magnetic resonance imaging scans in children with diffuse intrinsic pontine glioma.

Ko C, Kaushal A, Hammoud DA, Steffen-Smith EA, Bent R, Citrin D, Camphausen K, Warren KE.

Int J Radiat Oncol Biol Phys. 2012 Jul 15;83(4):1252-1256. doi: 10.1016/j.ijrobp.2011.09.046. Epub 2012 Jan 25.


Genomic aberrations in pediatric diffuse intrinsic pontine gliomas.

Warren KE, Killian K, Suuriniemi M, Wang Y, Quezado M, Meltzer PS.

Neuro Oncol. 2012 Mar;14(3):326-32. doi: 10.1093/neuonc/nor190. Epub 2011 Nov 7.


A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study.

Warren KE, Gururangan S, Geyer JR, McLendon RE, Poussaint TY, Wallace D, Balis FM, Berg SL, Packer RJ, Goldman S, Minturn JE, Pollack IF, Boyett JM, Kun LE.

J Neurooncol. 2012 Feb;106(3):643-9. doi: 10.1007/s11060-011-0709-z. Epub 2011 Oct 4.


Predicting outcome of children with diffuse intrinsic pontine gliomas using multiparametric imaging.

Hipp SJ, Steffen-Smith E, Hammoud D, Shih JH, Bent R, Warren KE.

Neuro Oncol. 2011 Aug;13(8):904-9. doi: 10.1093/neuonc/nor076. Epub 2011 Jul 13.

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