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Items: 1 to 50 of 1129

1.

The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent.

Rayes J, Jadoui S, Lax S, Gros A, Wichaiyo S, Ollivier V, Denis CV, Ware J, Nieswandt B, Jandrot-Perrus M, Watson SP, Ho-Tin-Noé B.

Haematologica. 2018 Feb 1. pii: haematol.2017.182162. doi: 10.3324/haematol.2017.182162. [Epub ahead of print]

2.

Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo.

Stark K, Schubert I, Joshi U, Kilani B, Hoseinpour P, Thakur M, Grünauer P, Pfeiler S, Schmidergall T, Stockhausen S, Bäumer M, Chandraratne S, von Brühl ML, Lorenz M, Coletti R, Reese S, Laitinen I, Wörmann SM, Algül H, Bruns CJ, Ware J, Mackman N, Engelmann B, Massberg S.

Arterioscler Thromb Vasc Biol. 2018 Feb 1. pii: ATVBAHA.117.310262. doi: 10.1161/ATVBAHA.117.310262. [Epub ahead of print]

PMID:
29419408
3.

Preoperative KOOS and SF-36 Scores Are Associated With the Development of Symptomatic Knee Osteoarthritis at 7 Years After Anterior Cruciate Ligament Reconstruction.

Ware JK, Owens BD, Akelman MR, Karamchedu NP, Fadale PD, Hulstyn MJ, Shalvoy RM, Badger GJ, Fleming BC.

Am J Sports Med. 2018 Feb 1:363546517751661. doi: 10.1177/0363546517751661. [Epub ahead of print]

PMID:
29401408
4.

CardioClassifier: disease- and gene-specific computational decision support for clinical genome interpretation.

Whiffin N, Walsh R, Govind R, Edwards M, Ahmad M, Zhang X, Tayal U, Buchan R, Midwinter W, Wilk AE, Najgebauer H, Francis C, Wilkinson S, Monk T, Brett L, O'Regan DP, Prasad SK, Morris-Rosendahl DJ, Barton PJR, Edwards E, Ware JS, Cook SA.

Genet Med. 2018 Jan 25. doi: 10.1038/gim.2017.258. [Epub ahead of print]

PMID:
29369293
5.

Adaptation and validation of the ACMG/AMP variant classification framework for MYH7-associated inherited cardiomyopathies: recommendations by ClinGen's Inherited Cardiomyopathy Expert Panel.

Kelly MA, Caleshu C, Morales A, Buchan J, Wolf Z, Harrison SM, Cook S, Dillon MW, Garcia J, Haverfield E, Jongbloed JDH, Macaya D, Manrai A, Orland K, Richard G, Spoonamore K, Thomas M, Thomson K, Vincent LM, Walsh R, Watkins H, Whiffin N, Ingles J, van Tintelen JP, Semsarian C, Ware JS, Hershberger R, Funke B.

Genet Med. 2018 Jan 4. doi: 10.1038/gim.2017.218. [Epub ahead of print]

PMID:
29300372
6.

The molecular evolutionary dynamics of oxidative phosphorylation (OXPHOS) genes in Hymenoptera.

Li Y, Zhang R, Liu S, Donath A, Peters RS, Ware J, Misof B, Niehuis O, Pfrender ME, Zhou X.

BMC Evol Biol. 2017 Dec 28;17(1):269. doi: 10.1186/s12862-017-1111-z.

7.

Role of titin in cardiomyopathy: from DNA variants to patient stratification.

Ware JS, Cook SA.

Nat Rev Cardiol. 2017 Dec 14. doi: 10.1038/nrcardio.2017.190. [Epub ahead of print] Review.

PMID:
29238064
8.

Lateral Patellofemoral Ligament: An Anatomic Study.

Shah KN, DeFroda SF, Ware JK, Koruprolu SC, Owens BD.

Orthop J Sports Med. 2017 Dec 4;5(12):2325967117741439. doi: 10.1177/2325967117741439. eCollection 2017 Dec.

9.

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets.

Quach ME, Dragovich MA, Chen W, Syed AK, Cao W, Liang X, Deng W, De Meyer SF, Zhu G, Peng J, Ni H, Bennett CM, Hou M, Ware J, Deckmyn H, Zhang XF, Li R.

Blood. 2018 Feb 15;131(7):787-796. doi: 10.1182/blood-2017-05-784975. Epub 2017 Dec 4.

PMID:
29203584
10.

Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.

Miller DC, Harmer SC, Poliandri A, Nobles M, Edwards EC, Ware JS, Sharp TV, McKay TR, Dunkel L, Lambiase PD, Tinker A.

Stem Cell Res. 2017 Dec;25:233-244. doi: 10.1016/j.scr.2017.11.003. Epub 2017 Nov 7.

11.

Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets.

Chen W, Druzak SA, Wang Y, Josephson CD, Hoffmeister KM, Ware J, Li R.

Arterioscler Thromb Vasc Biol. 2017 Dec;37(12):2271-2279. doi: 10.1161/ATVBAHA.117.310062. Epub 2017 Nov 2.

PMID:
29097365
12.

Phenotype and Clinical Outcomes of Titin Cardiomyopathy.

Tayal U, Newsome S, Buchan R, Whiffin N, Halliday B, Lota A, Roberts A, Baksi AJ, Voges I, Midwinter W, Wilk A, Govind R, Walsh R, Daubeney P, Jarman JWE, Baruah R, Frenneaux M, Barton PJ, Pennell D, Ware JS, Prasad SK, Cook SA.

J Am Coll Cardiol. 2017 Oct 31;70(18):2264-2274. doi: 10.1016/j.jacc.2017.08.063.

13.

A phase IB dose-escalation study of the safety and pharmacokinetics of pictilisib in combination with either paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed and cisplatin (with or without bevacizumab) in patients with advanced non-small cell lung cancer.

Soria JC, Adjei AA, Bahleda R, Besse B, Ferte C, Planchard D, Zhou J, Ware J, Morrissey K, Shankar G, Lin W, Schutzman JL, Dy GK, Groen HJM.

Eur J Cancer. 2017 Nov;86:186-196. doi: 10.1016/j.ejca.2017.08.027. Epub 2017 Oct 6.

PMID:
28992562
14.

The Lipid-Rich Plaque Study of vulnerable plaques and vulnerable patients: Study design and rationale.

Waksman R, Torguson R, Spad MA, Garcia-Garcia H, Ware J, Wang R, Madden S, Shah P, Muller J.

Am Heart J. 2017 Oct;192:98-104. doi: 10.1016/j.ahj.2017.02.010. Epub 2017 Feb 16. Review.

PMID:
28938968
15.

Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences.

Chenoweth MJ, Ware JJ, Zhu AZX, Cole CB, Cox LS, Nollen N, Ahluwalia JS, Benowitz NL, Schnoll RA, Hawk LW Jr, Cinciripini PM, George TP, Lerman C, Knight J, Tyndale RF; PGRN-PNAT Research Group.

Addiction. 2018 Mar;113(3):509-523. doi: 10.1111/add.14032. Epub 2017 Nov 2.

PMID:
28921760
16.

Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.

Heinig M, Adriaens ME, Schafer S, van Deutekom HWM, Lodder EM, Ware JS, Schneider V, Felkin LE, Creemers EE, Meder B, Katus HA, Rühle F, Stoll M, Cambien F, Villard E, Charron P, Varro A, Bishopric NH, George AL Jr, Dos Remedios C, Moreno-Moral A, Pesce F, Bauerfeind A, Rüschendorf F, Rintisch C, Petretto E, Barton PJ, Cook SA, Pinto YM, Bezzina CR, Hubner N.

Genome Biol. 2017 Sep 14;18(1):170. doi: 10.1186/s13059-017-1286-z.

17.

A Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of Pictilisib in Combination with Erlotinib in Patients with Advanced Solid Tumors.

Leong S, Moss RA, Bowles DW, Ware JA, Zhou J, Spoerke JM, Lackner MR, Shankar G, Schutzman JL, van der Noll R, Voest EE, Schellens JHM.

Oncologist. 2017 Dec;22(12):1491-1499. doi: 10.1634/theoncologist.2017-0090. Epub 2017 Aug 10.

PMID:
28798270
18.

Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia.

Ware JS, Wain LV, Channavajjhala SK, Jackson VE, Edwards E, Lu R, Siew K, Jia W, Shrine N, Kinnear S, Jalland M, Henry AP, Clayton J, O'Shaughnessy KM, Tobin MD, Schuster VL, Cook S, Hall IP, Glover M.

J Clin Invest. 2017 Sep 1;127(9):3367-3374. doi: 10.1172/JCI89812. Epub 2017 Aug 7.

19.

Combining "Bottom-up" and "Top-down" Approaches to Assess the Impact of Food and Gastric pH on Pictilisib (GDC-0941) Pharmacokinetics.

Lu T, Fraczkiewicz G, Salphati L, Budha N, Dalziel G, Smelick GS, Morrissey KM, Davis JD, Jin JY, Ware JA.

CPT Pharmacometrics Syst Pharmacol. 2017 Nov;6(11):747-755. doi: 10.1002/psp4.12228. Epub 2017 Oct 17.

20.

Therapeutic Climate Within a Treatment Program for Categorical Deniers.

Ware J.

Int J Offender Ther Comp Criminol. 2017 Jul 1:306624X17717143. doi: 10.1177/0306624X17717143. [Epub ahead of print]

PMID:
28681641
21.

Commentary on: "Influence of OATP1B1 Function on the Disposition of Sorafenib-β-D-Glucuronide".

Morrissey KM, Benet LZ, Ware JA.

Clin Transl Sci. 2017 Jul;10(4):240-241. doi: 10.1111/cts.12476. Epub 2017 Jun 29. No abstract available.

22.

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis.

Dütting S, Gaits-Iacovoni F, Stegner D, Popp M, Antkowiak A, van Eeuwijk JMM, Nurden P, Stritt S, Heib T, Aurbach K, Angay O, Cherpokova D, Heinz N, Baig AA, Gorelashvili MG, Gerner F, Heinze KG, Ware J, Krohne G, Ruggeri ZM, Nurden AT, Schulze H, Modlich U, Pleines I, Brakebusch C, Nieswandt B.

Nat Commun. 2017 Jun 15;8:15838. doi: 10.1038/ncomms15838.

23.

Personally Identifiable Information in State Laws: Use, Release, and Collaboration at Health Departments.

Begley EB, Ware JM, Hexem SA, Rapposelli K, Thompson K, Penn MS, Aquino GA.

Am J Public Health. 2017 Aug;107(8):1272-1276. doi: 10.2105/AJPH.2017.303862. Epub 2017 Jun 22.

PMID:
28640676
24.

ClinVar data parsing.

Zhang X, Minikel EV, O'Donnell-Luria AH, MacArthur DG, Ware JS, Weisburd B.

Wellcome Open Res. 2017 May 23;2:33. doi: 10.12688/wellcomeopenres.11640.1. eCollection 2017.

25.

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes.

Alamo L, Ware JS, Pinto A, Gillilan RE, Seidman JG, Seidman CE, Padrón R.

Elife. 2017 Jun 13;6. pii: e24634. doi: 10.7554/eLife.24634.

26.

Does coffee consumption impact on heaviness of smoking?

Ware JJ, Tanner JA, Taylor AE, Bin Z, Haycock P, Bowden J, Rogers PJ, Davey Smith G, Tyndale RF, Munafò MR.

Addiction. 2017 Oct;112(10):1842-1853. doi: 10.1111/add.13888. Epub 2017 Jul 12.

27.

Using high-resolution variant frequencies to empower clinical genome interpretation.

Whiffin N, Minikel E, Walsh R, O'Donnell-Luria AH, Karczewski K, Ing AY, Barton PJR, Funke B, Cook SA, MacArthur D, Ware JS.

Genet Med. 2017 Oct;19(10):1151-1158. doi: 10.1038/gim.2017.26. Epub 2017 May 18.

28.

Truncating Variants in Titin Independently Predict Early Arrhythmias in Patients With Dilated Cardiomyopathy.

Tayal U, Newsome S, Buchan R, Whiffin N, Walsh R, Barton PJ, Ware JS, Cook SA, Prasad SK.

J Am Coll Cardiol. 2017 May 16;69(19):2466-2468. doi: 10.1016/j.jacc.2017.03.530. No abstract available.

29.

Utility of Post-Mortem Genetic Testing in Cases of Sudden Arrhythmic Death Syndrome.

Lahrouchi N, Raju H, Lodder EM, Papatheodorou E, Ware JS, Papadakis M, Tadros R, Cole D, Skinner JR, Crawford J, Love DR, Pua CJ, Soh BY, Bhalshankar JD, Govind R, Tfelt-Hansen J, Winkel BG, van der Werf C, Wijeyeratne YD, Mellor G, Till J, Cohen MC, Tome-Esteban M, Sharma S, Wilde AAM, Cook SA, Bezzina CR, Sheppard MN, Behr ER.

J Am Coll Cardiol. 2017 May 2;69(17):2134-2145. doi: 10.1016/j.jacc.2017.02.046.

30.

Effective Radiology Reporting.

Ware JB, Jha S, Hoang JK, Baker S, Wruble J.

J Am Coll Radiol. 2017 Jun;14(6):838-839. doi: 10.1016/j.jacr.2017.01.045. Epub 2017 Apr 21. No abstract available.

PMID:
28434849
31.

Effect of Continuous Positive Airway Pressure Treatment on Health-Related Quality of Life and Sleepiness in High Cardiovascular Risk Individuals With Sleep Apnea: Best Apnea Interventions for Research (BestAIR) Trial.

Zhao YY, Wang R, Gleason KJ, Lewis EF, Quan SF, Toth CM, Morrical M, Rueschman M, Weng J, Ware JH, Mittleman MA, Redline S; BestAIR Investigators.

Sleep. 2017 Apr 1;40(4). doi: 10.1093/sleep/zsx040.

PMID:
28419387
32.

Megakaryocytes compensate for Kit insufficiency in murine arthritis.

Cunin P, Penke LR, Thon JN, Monach PA, Jones T, Chang MH, Chen MM, Melki I, Lacroix S, Iwakura Y, Ware J, Gurish MF, Italiano JE, Boilard E, Nigrovic PA.

J Clin Invest. 2017 May 1;127(5):1714-1724. doi: 10.1172/JCI84598. Epub 2017 Apr 4.

33.

Natural History of Patients With Perilesional Edema Around Taenia solium Calcified Granulomas.

Nash TE, Ware JM, Mahanty S.

J Infect Dis. 2017 Apr 1;215(7):1141-1147. doi: 10.1093/infdis/jix027.

PMID:
28368546
34.

Phase I Dose-Escalation Study of Taselisib, an Oral PI3K Inhibitor, in Patients with Advanced Solid Tumors.

Juric D, Krop I, Ramanathan RK, Wilson TR, Ware JA, Sanabria Bohorquez SM, Savage HM, Sampath D, Salphati L, Lin RS, Jin H, Parmar H, Hsu JY, Von Hoff DD, Baselga J.

Cancer Discov. 2017 Jul;7(7):704-715. doi: 10.1158/2159-8290.CD-16-1080. Epub 2017 Mar 22.

PMID:
28331003
35.

Varying the item format improved the range of measurement in patient-reported outcome measures assessing physical function.

Liegl G, Gandek B, Fischer HF, Bjorner JB, Ware JE Jr, Rose M, Fries JF, Nolte S.

Arthritis Res Ther. 2017 Mar 21;19(1):66. doi: 10.1186/s13075-017-1273-5.

36.

Inter-Subject Variability of Axonal Injury in Diffuse Traumatic Brain Injury.

Ware JB, Hart T, Whyte J, Rabinowitz A, Detre JA, Kim J.

J Neurotrauma. 2017 Jul 15;34(14):2243-2253. doi: 10.1089/neu.2016.4817. Epub 2017 May 3.

PMID:
28314375
37.

Statistical Methods in the Journal - An Update.

Sato Y, Gosho M, Nagashima K, Takahashi S, Ware JH, Laird NM.

N Engl J Med. 2017 Mar 16;376(11):1086-1087. doi: 10.1056/NEJMc1616211. No abstract available.

38.

Habitat degradation affects the summer activity of polar bears.

Ware JV, Rode KD, Bromaghin JF, Douglas DC, Wilson RR, Regehr EV, Amstrup SC, Durner GM, Pagano AM, Olson J, Robbins CT, Jansen HT.

Oecologia. 2017 May;184(1):87-99. doi: 10.1007/s00442-017-3839-y. Epub 2017 Feb 28.

PMID:
28247129
39.

Neurodevelopmental Outcome in Children after Fetal Cardiac Intervention for Aortic Stenosis with Evolving Hypoplastic Left Heart Syndrome.

Laraja K, Sadhwani A, Tworetzky W, Marshall AC, Gauvreau K, Freud L, Hass C, Dunbar-Masterson C, Ware J, Lafranchi T, Wilkins-Haug L, Newburger JW.

J Pediatr. 2017 May;184:130-136.e4. doi: 10.1016/j.jpeds.2017.01.034. Epub 2017 Feb 21.

PMID:
28233547
40.

An evaluation of increasing sample size based on conditional power.

Gaffney M, Ware JH.

J Biopharm Stat. 2017 Feb 6:1-11. doi: 10.1080/10543406.2017.1289943. [Epub ahead of print]

PMID:
28166460
41.

Validity and Responsiveness of the Knee Injury and Osteoarthritis Outcome Score: A Comparative Study Among Total Knee Replacement Patients.

Gandek B, Ware JE Jr.

Arthritis Care Res (Hoboken). 2017 Jun;69(6):817-825. doi: 10.1002/acr.23193. Epub 2017 May 8.

PMID:
28085998
42.

Defining the genetic architecture of hypertrophic cardiomyopathy: re-evaluating the role of non-sarcomeric genes.

Walsh R, Buchan R, Wilk A, John S, Felkin LE, Thomson KL, Chiaw TH, Loong CCW, Pua CJ, Raphael C, Prasad S, Barton PJ, Funke B, Watkins H, Ware JS, Cook SA.

Eur Heart J. 2017 Dec 7;38(46):3461-3468. doi: 10.1093/eurheartj/ehw603.

PMID:
28082330
43.

Histiocytoid cardiomyopathy and microphthalmia with linear skin defects syndrome: phenotypes linked by truncating variants in NDUFB11.

Rea G, Homfray T, Till J, Roses-Noguer F, Buchan RJ, Wilkinson S, Wilk A, Walsh R, John S, McKee S, Stewart FJ, Murday V, Taylor RW, Ashworth M, Baksi AJ, Daubeney P, Prasad S, Barton PJR, Cook SA, Ware JS.

Cold Spring Harb Mol Case Stud. 2017 Jan;3(1):a001271. doi: 10.1101/mcs.a001271.

44.

Thrombocytopathy leading to impaired in vivo haemostasis and thrombosis in platelet type von Willebrand disease.

Kaur H, Corscadden K, Ware J, Othman M.

Thromb Haemost. 2017 Feb 28;117(3):543-555. doi: 10.1160/TH16-04-0317. Epub 2016 Dec 22.

PMID:
28004055
45.

Pharmacogenomics in the age of personalized medicine.

Dickmann LJ, Ware JA.

Drug Discov Today Technol. 2016 Sep - Dec;21-22:11-16. doi: 10.1016/j.ddtec.2016.11.003. Review.

PMID:
27978982
46.

Incorporating fossils into hypotheses of insect phylogeny.

Ware JL, Barden P.

Curr Opin Insect Sci. 2016 Dec;18:69-76. doi: 10.1016/j.cois.2016.10.003. Epub 2016 Oct 19. Review.

PMID:
27939713
47.

Advances using molecular data in insect systematics.

Kjer K, Borowiec ML, Frandsen PB, Ware J, Wiegmann BM.

Curr Opin Insect Sci. 2016 Dec;18:40-47. doi: 10.1016/j.cois.2016.09.006. Epub 2016 Oct 14. Review.

PMID:
27939709
49.

Titin-truncating variants affect heart function in disease cohorts and the general population.

Schafer S, de Marvao A, Adami E, Fiedler LR, Ng B, Khin E, Rackham OJ, van Heesch S, Pua CJ, Kui M, Walsh R, Tayal U, Prasad SK, Dawes TJ, Ko NS, Sim D, Chan LL, Chin CW, Mazzarotto F, Barton PJ, Kreuchwig F, de Kleijn DP, Totman T, Biffi C, Tee N, Rueckert D, Schneider V, Faber A, Regitz-Zagrosek V, Seidman JG, Seidman CE, Linke WA, Kovalik JP, O'Regan D, Ware JS, Hubner N, Cook SA.

Nat Genet. 2017 Jan;49(1):46-53. doi: 10.1038/ng.3719. Epub 2016 Nov 21.

50.

Aerosol lidar observations of atmospheric mixing in Los Angeles: Climatology and implications for greenhouse gas observations.

Ware J, Kort EA, DeCola P, Duren R.

J Geophys Res Atmos. 2016 Aug 27;121(16):9862-9878. Epub 2016 Aug 23.

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