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Prophylactic Antimicrobial Therapy for Acute Aspiration Pneumonitis.

Dragan V, Wei L, Elligsen M, Kiss A, Walker SAN, Leis JA.

Clin Infect Dis. 2018 Feb 9. doi: 10.1093/cid/ciy120. [Epub ahead of print]


Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma.

Zhang Y, Poobalasingam T, Yates LL, Walker SA, Taylor MS, Chessum L, Harrison J, Tsaprouni L, Adcock IM, Lloyd CM, Cookson WO, Moffatt MF, Dean CH.

Dis Model Mech. 2018 Jan 29;11(1). pii: dmm031369. doi: 10.1242/dmm.031369.


Steady-State Pharmacokinetics of Oral Ciprofloxacin in Continuous Cycling Peritoneal Dialysis Patients: Brief Report.

Lee C, Walker SAN, Palmay L, Walker SE, Tobe S, Simor A.

Perit Dial Int. 2018 Jan-Feb;38(1):73-76. doi: 10.3747/pdi.2017.00052.


Period-dependent Associations between Hypotension during and for Four Days after Noncardiac Surgery and a Composite of Myocardial Infarction and Death: A Substudy of the POISE-2 Trial.

Sessler DI, Meyhoff CS, Zimmerman NM, Mao G, Leslie K, Vásquez SM, Balaji P, Alvarez-Garcia J, Cavalcanti AB, Parlow JL, Rahate PV, Seeberger MD, Gossetti B, Walker SA, Premchand RK, Dahl RM, Duceppe E, Rodseth R, Botto F, Devereaux PJ.

Anesthesiology. 2018 Feb;128(2):317-327. doi: 10.1097/ALN.0000000000001985.


A meta-analysis and systematic review of reactivity to judgements of learning.

Double KS, Birney DP, Walker SA.

Memory. 2017 Nov 21:1-10. doi: 10.1080/09658211.2017.1404111. [Epub ahead of print]


A prospective study evaluating tobramycin pharmacokinetics and optimal once daily dosing in burn patients.

Lee C, Walker SAN, Walker SE, Seto W, Simor A, Jeschke M.

Burns. 2017 Dec;43(8):1766-1774. doi: 10.1016/j.burns.2017.05.009. Epub 2017 Jun 21.


Point-of-care Beta-lactam Allergy Skin Testing by Antimicrobial Stewardship Programs: A Pragmatic Multicenter Prospective Evaluation.

Leis JA, Palmay L, Ho G, Raybardhan S, Gill S, Kan T, Campbell J, Kiss A, McCready JB, Das P, Minnema B, Powis JE, Walker SAN, Ferguson H, Wong B, Weber E.

Clin Infect Dis. 2017 Jun 1. doi: 10.1093/cid/cix512. [Epub ahead of print]


Correlative Live Cell and Super Resolution Imaging of Autophagosome Formation.

Walker SA, Karanasios E, Ktistakis NT.

Methods Enzymol. 2017;587:1-20. doi: 10.1016/bs.mie.2016.09.050. Epub 2016 Nov 17.


Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.

Poobalasingam T, Yates LL, Walker SA, Pereira M, Gross NY, Ali A, Kolatsi-Joannou M, Jarvelin MR, Pekkanen J, Papakrivopoulou E, Long DA, Griffiths M, Wagner D, Königshoff M, Hind M, Minelli C, Lloyd CM, Dean CH.

Dis Model Mech. 2017 Apr 1;10(4):409-423. doi: 10.1242/dmm.028175. Epub 2017 Feb 24.


Elimination of Screening Urine Cultures Prior to Elective Joint Arthroplasty.

Lamb MJ, Baillie L, Pajak D, Flynn J, Bansal V, Simor A, Vearncombe M, Walker SA, Clark S, Gollish J, Leis JA.

Clin Infect Dis. 2017 Mar 15;64(6):806-809. doi: 10.1093/cid/ciw848.


Assembly of early machinery for autophagy induction: novel insights from high resolution microscopy.

Ktistakis NT, Walker SA, Karanasios E.

Oncotarget. 2016 Dec 27;7(52):85678-85679. doi: 10.18632/oncotarget.13144. No abstract available.


A critical role for IRF5 in regulating allergic airway inflammation.

Byrne AJ, Weiss M, Mathie SA, Walker SA, Eames HL, Saliba D, Lloyd CM, Udalova IA.

Mucosal Immunol. 2017 May;10(3):716-726. doi: 10.1038/mi.2016.92. Epub 2016 Oct 19.


Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.

Löser S, Gregory LG, Zhang Y, Schaefer K, Walker SA, Buckley J, Denney L, Dean CH, Cookson WOC, Moffatt MF, Lloyd CM.

J Allergy Clin Immunol. 2017 May;139(5):1496-1507.e3. doi: 10.1016/j.jaci.2016.07.033. Epub 2016 Sep 10.


Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles.

Karanasios E, Walker SA, Okkenhaug H, Manifava M, Hummel E, Zimmermann H, Ahmed Q, Domart MC, Collinson L, Ktistakis NT.

Nat Commun. 2016 Aug 11;7:12420. doi: 10.1038/ncomms12420.


The Clinical Utility of Next Generation Sequencing Results in a Community-Based Hereditary Cancer Risk Program.

Bunnell AE, Garby CA, Pearson EJ, Walker SA, Panos LE, Blum JL.

J Genet Couns. 2017 Feb;26(1):105-112. doi: 10.1007/s10897-016-9985-2. Epub 2016 Jun 9.


Antibiotic Use and Need for Antimicrobial Stewardship in Long-Term Care.

Wu LD, Walker SA, Elligsen M, Palmay L, Simor A, Daneman N.

Can J Hosp Pharm. 2015 Nov-Dec;68(6):445-9. Erratum in: Can J Hosp Pharm. 2017 May-Jun;70(3):224.


Impact of infection with extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella species on outcome and hospitalization costs.

Maslikowska JA, Walker SA, Elligsen M, Mittmann N, Palmay L, Daneman N, Simor A.

J Hosp Infect. 2016 Jan;92(1):33-41. doi: 10.1016/j.jhin.2015.10.001. Epub 2015 Oct 22.


Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function.

Denney L, Byrne AJ, Shea TJ, Buckley JS, Pease JE, Herledan GM, Walker SA, Gregory LG, Lloyd CM.

Immunity. 2015 Nov 17;43(5):945-58. doi: 10.1016/j.immuni.2015.10.012.


Neurocognitive Function at the First-Line Failure and on the Second-Line Antiretroviral Therapy in Africa: Analyses From the EARNEST Trial.

Kambugu A, Thompson J, Hakim J, Tumukunde D, van Oosterhout JJ, Mwebaze R, Hoppe A, Abach J, Kwobah C, Arenas-Pinto A, Walker SA, Paton NI; EARNEST Trial Team.

J Acquir Immune Defic Syndr. 2016 Apr 15;71(5):506-13. doi: 10.1097/QAI.0000000000000898.


Impact of hospital length of stay on the distribution of Gram negative bacteria and likelihood of isolating a resistant organism in a Canadian burn center.

Wanis M, Walker SAN, Daneman N, Elligsen M, Palmay L, Simor A, Cartotto R.

Burns. 2016 Feb;42(1):104-111. doi: 10.1016/j.burns.2015.07.010. Epub 2015 Nov 5.


Microglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig.

Lafrenaye AD, Todani M, Walker SA, Povlishock JT.

J Neuroinflammation. 2015 Oct 6;12:186. doi: 10.1186/s12974-015-0405-6.


Low Earth orbit assessment of proton anisotropy using AP8 and AP9 trapped proton models.

Badavi FF, Walker SA, Santos Koos LM.

Life Sci Space Res (Amst). 2015 Apr;5:21-30. doi: 10.1016/j.lssr.2015.04.001. Epub 2015 Apr 9.


Point prevalence survey of antimicrobial utilization in a Canadian tertiary-care teaching hospital.

Lee C, Walker SA, Daneman N, Elligsen M, Palmay L, Coburn B, Simor A.

J Epidemiol Glob Health. 2015 Jun;5(2):143-50. doi: 10.1016/j.jegh.2014.06.003. Epub 2014 Aug 8.


Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life.

Lee DC, Walker SA, Byrne AJ, Gregory LG, Buckley J, Bush A, Shaheen SO, Saglani S, Lloyd CM.

Thorax. 2015 Jun;70(6):528-36. doi: 10.1136/thoraxjnl-2014-205280. Epub 2015 Apr 3.


Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthma.

Johnson JR, Folestad E, Rowley JE, Noll EM, Walker SA, Lloyd CM, Rankin SM, Pietras K, Eriksson U, Fuxe J.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 1;308(7):L658-71. doi: 10.1152/ajplung.00286.2014. Epub 2015 Jan 30.


Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge.

Mathie SA, Dixon KL, Walker SA, Tyrrell V, Mondhe M, O'Donnell VB, Gregory LG, Lloyd CM.

Allergy. 2015 Jan;70(1):80-9. doi: 10.1111/all.12536. Epub 2014 Nov 28.


Impact of second-line antiretroviral regimens on lipid profiles in an African setting: the DART trial sub-study.

Gomo ZA, Hakim JG, Walker SA, Tinago W, Mandozana G, Kityo C, Munderi P, Katabira E, Reid A, Gibb DM, Gilks CF; DART Team.

AIDS Res Ther. 2014 Oct 2;11(1):32. doi: 10.1186/1742-6405-11-32. eCollection 2014.


Lessons from audit and feedback of hospitalized patients with bacteriuria.

Leis JA, Palmay L, Elligsen M, Walker SA, Lee C, Daneman N.

Am J Infect Control. 2014 Oct;42(10):1136-7. doi: 10.1016/j.ajic.2014.06.020.


Specificity of elevated cerebrospinal fluid bilirubin in the investigation of subarachnoid haemorrhage.

Falconer HL, Walker SA, Peter Ashby J.

Ann Clin Biochem. 2015 May;52(Pt 3):404-6. doi: 10.1177/0004563214554463. Epub 2014 Sep 23.


Identifying barriers to medication discharge counselling by pharmacists.

Walker SA, Lo JK, Compani S, Ko E, Le MH, Marchesano R, Natanson R, Pradhan R, Rzyczniak G, Teo V, Vyas A.

Can J Hosp Pharm. 2014 May;67(3):203-12.


Effect of electron spin dynamics on solid-state dynamic nuclear polarization performance.

Siaw TA, Fehr M, Lund A, Latimer A, Walker SA, Edwards DT, Han SI.

Phys Chem Chem Phys. 2014 Sep 21;16(35):18694-706. doi: 10.1039/c4cp02013h.


Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease.

Vasiliou JE, Lui S, Walker SA, Chohan V, Xystrakis E, Bush A, Hawrylowicz CM, Saglani S, Lloyd CM.

Allergy. 2014 Oct;69(10):1380-9. doi: 10.1111/all.12465. Epub 2014 Aug 4.


Hospital-wide rollout of antimicrobial stewardship: a stepped-wedge randomized trial.

Palmay L, Elligsen M, Walker SA, Pinto R, Walker S, Einarson T, Simor A, Rachlis A, Mubareka S, Daneman N.

Clin Infect Dis. 2014 Sep 15;59(6):867-74. doi: 10.1093/cid/ciu445. Epub 2014 Jun 13.


Anthropometric measurements and lipid profiles to detect early lipodystrophy in antiretroviral therapy experienced HIV-infected children in the CHAPAS-3 trial.

Musiime V, Cook A, Kayiwa J, Zangata D, Nansubuga C, Arach B, Kenny J, Wavamunno P, Komunyena J, Kabamba D, Asiimwe AR, Mirembe G, Abongomera G, Mulenga V, Kekitiinwa A, Kityo C, Walker SA, Klein N, Gibb DM; CHAPAS-3 trial team.

Antivir Ther. 2014;19(3):269-76. doi: 10.3851/IMP2695. Epub 2013 Oct 25.


Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations.

Snelgrove RJ, Gregory LG, Peiró T, Akthar S, Campbell GA, Walker SA, Lloyd CM.

J Allergy Clin Immunol. 2014 Sep;134(3):583-592.e6. doi: 10.1016/j.jaci.2014.02.002. Epub 2014 Mar 15.


Determination of vancomycin pharmacokinetics in neonates to develop practical initial dosing recommendations.

Kim J, Walker SA, Iaboni DC, Walker SE, Elligsen M, Dunn MS, Allen VG, Simor A.

Antimicrob Agents Chemother. 2014 May;58(5):2830-40. doi: 10.1128/AAC.01718-13. Epub 2014 Mar 10.


The immune system GTPase GIMAP6 interacts with the Atg8 homologue GABARAPL2 and is recruited to autophagosomes.

Pascall JC, Rotondo S, Mukadam AS, Oxley D, Webster J, Walker SA, Piron J, Carter C, Ktistakis NT, Butcher GW.

PLoS One. 2013 Oct 17;8(10):e77782. doi: 10.1371/journal.pone.0077782. eCollection 2013.


Clinical differences between younger and older adults with HIV/AIDS starting antiretroviral therapy in Uganda and Zimbabwe: a secondary analysis of the DART trial.

Parikh SM, Obuku EA, Walker SA, Semeere AS, Auerbach BJ, Hakim JG, Mayanja-Kizza H, Mugyenyi PN, Salata RA, Kityo CM; DART Trial Team.

PLoS One. 2013 Oct 2;8(10):e76158. doi: 10.1371/journal.pone.0076158. eCollection 2013.


Linear structures in the core of the Coma cluster of galaxies.

Sanders JS, Fabian AC, Churazov E, Schekochihin AA, Simionescu A, Walker SA, Werner N.

Science. 2013 Sep 20;341(6152):1365-8. doi: 10.1126/science.1238334.


Determination of tobramycin pharmacokinetics in burn patients to evaluate the potential utility of once-daily dosing in this population.

Vella D, Walker SA, Walker SE, Daneman N, Simor A.

J Burn Care Res. 2014 Jul-Aug;35(4):e240-9. doi: 10.1097/BCR.0b013e3182a226fb.


Dynamic association of the ULK1 complex with omegasomes during autophagy induction.

Karanasios E, Stapleton E, Manifava M, Kaizuka T, Mizushima N, Walker SA, Ktistakis NT.

J Cell Sci. 2013 Nov 15;126(Pt 22):5224-38. doi: 10.1242/jcs.132415. Epub 2013 Sep 6.


Live cell imaging of early autophagy events: omegasomes and beyond.

Karanasios E, Stapleton E, Walker SA, Manifava M, Ktistakis NT.

J Vis Exp. 2013 Jul 27;(77). doi: 10.3791/50484.


Temperature dependence of high field 13C dynamic nuclear polarization processes with trityl radicals below 35 Kelvin.

Walker SA, Edwards DT, Siaw TA, Armstrong BD, Han S.

Phys Chem Chem Phys. 2013 Sep 28;15(36):15106-20. doi: 10.1039/c3cp51628h.


Characteristics and requirements of basal autophagy in HEK 293 cells.

Musiwaro P, Smith M, Manifava M, Walker SA, Ktistakis NT.

Autophagy. 2013 Sep;9(9):1407-17. doi: 10.4161/auto.25455. Epub 2013 Jun 20.


IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma.

Saglani S, Lui S, Ullmann N, Campbell GA, Sherburn RT, Mathie SA, Denney L, Bossley CJ, Oates T, Walker SA, Bush A, Lloyd CM.

J Allergy Clin Immunol. 2013 Sep;132(3):676-685.e13. doi: 10.1016/j.jaci.2013.04.012. Epub 2013 Jun 4.


Identification of predictors of early infection in acute burn patients.

Schultz L, Walker SA, Elligsen M, Walker SE, Simor A, Mubareka S, Daneman N.

Burns. 2013 Nov;39(7):1355-66. doi: 10.1016/j.burns.2013.04.009. Epub 2013 May 8.


Pan-Arctic distributions of continental runoff in the Arctic Ocean.

Fichot CG, Kaiser K, Hooker SB, Amon RM, Babin M, Bélanger S, Walker SA, Benner R.

Sci Rep. 2013;3:1053. doi: 10.1038/srep01053. Epub 2013 Jan 11.


IL-25 drives remodelling in allergic airways disease induced by house dust mite.

Gregory LG, Jones CP, Walker SA, Sawant D, Gowers KH, Campbell GA, McKenzie AN, Lloyd CM.

Thorax. 2013 Jan;68(1):82-90. doi: 10.1136/thoraxjnl-2012-202003. Epub 2012 Oct 23.


Intra-axonal calcium changes after axotomy in wild-type and slow Wallerian degeneration axons.

Adalbert R, Morreale G, Paizs M, Conforti L, Walker SA, Roderick HL, Bootman MD, Siklós L, Coleman MP.

Neuroscience. 2012 Dec 6;225:44-54. doi: 10.1016/j.neuroscience.2012.08.056. Epub 2012 Sep 7.


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