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Items: 23

1.

Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer.

Borovski T, Vellinga TT, Laoukili J, Santo EE, Fatrai S, van Schelven S, Verheem A, Marvin DL, Ubink I, Borel Rinkes IHM, Kranenburg O.

Gut. 2017 Jun;66(6):1106-1115. doi: 10.1136/gutjnl-2016-311547. Epub 2016 Sep 26.

PMID:
27670374
2.

Maintenance of Clonogenic KIT(+) Human Colon Tumor Cells Requires Secretion of Stem Cell Factor by Differentiated Tumor Cells.

Fatrai S, van Schelven SJ, Ubink I, Govaert KM, Raats D, Koster J, Verheem A, Borel Rinkes IH, Kranenburg O.

Gastroenterology. 2015 Sep;149(3):692-704. doi: 10.1053/j.gastro.2015.05.003. Epub 2015 May 9.

PMID:
25962936
3.

SIRT1/PGC1α-Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer.

Vellinga TT, Borovski T, de Boer VC, Fatrai S, van Schelven S, Trumpi K, Verheem A, Snoeren N, Emmink BL, Koster J, Rinkes IH, Kranenburg O.

Clin Cancer Res. 2015 Jun 15;21(12):2870-9. doi: 10.1158/1078-0432.CCR-14-2290. Epub 2015 Mar 16.

4.

Impact of global Fxr deficiency on experimental acute pancreatitis and genetic variation in the FXR locus in human acute pancreatitis.

Nijmeijer RM, Schaap FG, Smits AJ, Kremer AE, Akkermans LM, Kroese AB, Rijkers GT, Schipper ME, Verheem A, Wijmenga C, Gooszen HG, van Erpecum KJ.

PLoS One. 2014 Dec 3;9(12):e114393. doi: 10.1371/journal.pone.0114393. eCollection 2014.

5.

GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer.

Emmink BL, Laoukili J, Kipp AP, Koster J, Govaert KM, Fatrai S, Verheem A, Steller EJ, Brigelius-Flohé R, Jimenez CR, Borel Rinkes IH, Kranenburg O.

Cancer Res. 2014 Nov 15;74(22):6717-30. doi: 10.1158/0008-5472.CAN-14-1645. Epub 2014 Sep 26.

6.

The secretome of colon cancer stem cells contains drug-metabolizing enzymes.

Emmink BL, Verheem A, Van Houdt WJ, Steller EJ, Govaert KM, Pham TV, Piersma SR, Borel Rinkes IH, Jimenez CR, Kranenburg O.

J Proteomics. 2013 Oct 8;91:84-96. doi: 10.1016/j.jprot.2013.06.027. Epub 2013 Jul 5.

PMID:
23835434
7.

Fibrin-thrombin coated sealant increases strength of esophagogastric anastomoses in a rat model.

Verhage RJ, Ruiz A, Verheem A, Goldschmeding R, Borel Rinkes IH, van Hillegersberg R.

J Surg Res. 2012 Aug;176(2):e57-63. doi: 10.1016/j.jss.2011.12.028. Epub 2012 Mar 10.

PMID:
22445453
8.

Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target.

Van Houdt WJ, Emmink BL, Pham TV, Piersma SR, Verheem A, Vries RG, Fratantoni SA, Pronk A, Clevers H, Borel Rinkes IH, Jimenez CR, Kranenburg O.

Mol Cell Proteomics. 2011 Dec;10(12):M111.011353. doi: 10.1074/mcp.M111.011353. Epub 2011 Jul 25.

9.

A role for CD95 signaling in ischemia/reperfusion-induced invasion and outgrowth of colorectal micrometastases in mouse liver.

Nijkamp MW, Hoogwater FJ, Govaert KM, Steller EJ, Verheem A, Kranenburg O, Borel Rinkes IH.

J Surg Oncol. 2011 Aug 1;104(2):198-204. doi: 10.1002/jso.21915. Epub 2011 Mar 24.

PMID:
21506133
10.

Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan.

Emmink BL, Van Houdt WJ, Vries RG, Hoogwater FJ, Govaert KM, Verheem A, Nijkamp MW, Steller EJ, Jimenez CR, Clevers H, Borel Rinkes IH, Kranenburg O.

Gastroenterology. 2011 Jul;141(1):269-78. doi: 10.1053/j.gastro.2011.03.052. Epub 2011 Apr 1.

PMID:
21459094
11.

Pretreatment but not treatment with probiotics abolishes mouse intestinal barrier dysfunction in acute pancreatitis.

Rychter JW, van Minnen LP, Verheem A, Timmerman HM, Rijkers GT, Schipper ME, Gooszen HG, Akkermans LM, Kroese AB.

Surgery. 2009 Feb;145(2):157-67. doi: 10.1016/j.surg.2008.09.011.

PMID:
19167970
12.

Modification of intestinal flora with multispecies probiotics reduces bacterial translocation and improves clinical course in a rat model of acute pancreatitis.

van Minnen LP, Timmerman HM, Lutgendorff F, Verheem A, Harmsen W, Konstantinov SR, Smidt H, Visser MR, Rijkers GT, Gooszen HG, Akkermans LM.

Surgery. 2007 Apr;141(4):470-80. Epub 2007 Jan 25.

PMID:
17383524
13.

Selective portal clamping to minimize hepatic ischaemia-reperfusion damage and avoid accelerated outgrowth of experimental colorectal liver metastases.

van der Bilt JD, Kranenburg O, Verheem A, van Hillegersberg R, Borel Rinkes IH.

Br J Surg. 2006 Aug;93(8):1015-22.

PMID:
16736538
14.

Cholesterol crystals enhance and phospholipids protect against pancreatitis induced by hydrophobic bile salts: a rat model study.

van Minnen LP, Venneman NG, van Dijk JE, Verheem A, Gooszen HG, Akkermans LM, van Erpecum KJ.

Pancreas. 2006 May;32(4):369-75.

PMID:
16670619
15.

Indomethacin disrupts the protective effect of phosphatidylcholine against bile salt-induced ileal mucosa injury.

Venneman NG, Petruzzelli M, van Dijk JE, Verheem A, Akkermans LM, Kroese AB, van Erpecum KJ.

Eur J Clin Invest. 2006 Feb;36(2):105-12.

PMID:
16436092
16.

Effects of subtotal colectomy on bacterial translocation during experimental acute pancreatitis.

van Minnen LP, Nieuwenhuijs VB, de Bruijn MT, Verheem A, Visser MR, van Dijk JE, Akkermans LM, Gooszen HG.

Pancreas. 2006 Jan;32(1):110-4.

PMID:
16340752
17.

Interdigestive small bowel motility and duodenal bacterial overgrowth in experimental acute pancreatitis.

Van Felius ID, Akkermans LM, Bosscha K, Verheem A, Harmsen W, Visser MR, Gooszen HG.

Neurogastroenterol Motil. 2003 Jun;15(3):267-76.

PMID:
12787336
18.

Adverse effects of the antiangiogenic agent angiostatin on the healing of experimental colonic anastomoses.

te Velde EA, Voest EE, van Gorp JM, Verheem A, Hagendoorn J, Gebbink MF, Borel Rinkes IH.

Ann Surg Oncol. 2002 Apr;9(3):303-9.

PMID:
11923139
19.

The effects of ABT-229 and octreotide on interdigestive small bowel motility, bacterial overgrowth and bacterial translocation in rats.

Nieuwenhuijs VB, van Duijvenbode-Beumer H, Verheem A, Visser MR, Verhoef J, Gooszen HG, Akkermans LM.

Eur J Clin Invest. 1999 Jan;29(1):33-40.

PMID:
10092986
20.

The role of interdigestive small bowel motility in the regulation of gut microflora, bacterial overgrowth, and bacterial translocation in rats.

Nieuwenhuijs VB, Verheem A, van Duijvenbode-Beumer H, Visser MR, Verhoef J, Gooszen HG, Akkermans LM.

Ann Surg. 1998 Aug;228(2):188-93.

21.

Disrupted bile flow affects interdigestive small bowel motility in rats.

Nieuwenhuijs VB, Luiking YC, Verheem A, vanBerge-Henegouwen GP, Gooszen HG, Akkermans LM.

Surgery. 1997 Sep;122(3):600-8.

PMID:
9308619
22.

Effect of bile salts on in vitro gallbladder motility: preliminary study.

Stolk MF, Van de Heijning BJ, Van Erpecum KJ, Verheem A, Akkermans LM, Van Berge-Henegouwen GP.

Ital J Gastroenterol. 1996 Feb-Mar;28(2):105-10.

PMID:
8782005
23.

Proton magnetic resonance imaging in experimental cerebral ischaemia.

van Rijen PC, Verheem A, Tulleken CA.

Acta Neurochir Suppl (Wien). 1988;43:162-7.

PMID:
3213644

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