Sort by
Items per page

Send to

Choose Destination

Search results

Items: 21


Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.

Steeland S, Gorlé N, Vandendriessche C, Balusu S, Brkic M, Van Cauwenberghe C, Van Imschoot G, Van Wonterghem E, De Rycke R, Kremer A, Lippens S, Stopa E, Johanson CE, Libert C, Vandenbroucke RE.

EMBO Mol Med. 2018 Feb 22. pii: e8300. doi: 10.15252/emmm.201708300. [Epub ahead of print]


The choroid plexus epithelium as a novel player in the stomach-brain axis during Helicobacter infection.

Gorlé N, Blaecher C, Bauwens E, Vandendriessche C, Balusu S, Vandewalle J, Van Cauwenberghe C, Van Wonterghem E, Van Imschoot G, Liu C, Ducatelle R, Libert C, Haesebrouck F, Smet A, Vandenbroucke RE.

Brain Behav Immun. 2018 Mar;69:35-47. doi: 10.1016/j.bbi.2017.12.010. Epub 2017 Dec 16.


Simultaneous Inhibition of Tumor Necrosis Factor Receptor 1 and Matrix Metalloproteinase 8 Completely Protects Against Acute Inflammation and Sepsis.

Steeland S, Van Ryckeghem S, Vandewalle J, Ballegeer M, Van Wonterghem E, Eggermont M, Decruyenaere J, De Bus L, Libert C, Vandenbroucke RE.

Crit Care Med. 2018 Jan;46(1):e67-e75. doi: 10.1097/CCM.0000000000002813.


Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability.

Xiong R, Vandenbroucke RE, Broos K, Brans T, Van Wonterghem E, Libert C, Demeester J, De Smedt SC, Braeckmans K.

Nat Commun. 2016 Sep 22;7:12982. doi: 10.1038/ncomms12982.


Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles.

Balusu S, Van Wonterghem E, De Rycke R, Raemdonck K, Stremersch S, Gevaert K, Brkic M, Demeestere D, Vanhooren V, Hendrix A, Libert C, Vandenbroucke RE.

EMBO Mol Med. 2016 Oct 4;8(10):1162-1183. doi: 10.15252/emmm.201606271. Print 2016 Oct.


Corrigendum: Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.

Kessler SM, Laggai S, Van Wonterghem E, Gemperlein K, Müller R, Haybaeck J, Vandenbroucke RE, Ogris M, Libert C, Kiemer AK.

Front Physiol. 2016 Jul 29;7:328. doi: 10.3389/fphys.2016.00328. eCollection 2016.


Comparing exosome-like vesicles with liposomes for the functional cellular delivery of small RNAs.

Stremersch S, Vandenbroucke RE, Van Wonterghem E, Hendrix A, De Smedt SC, Raemdonck K.

J Control Release. 2016 Jun 28;232:51-61. doi: 10.1016/j.jconrel.2016.04.005. Epub 2016 Apr 9.


Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8.

Demeestere D, Dejonckheere E, Steeland S, Hulpiau P, Haustraete J, Devoogdt N, Wichert R, Becker-Pauly C, Van Wonterghem E, Dewaele S, Van Imschoot G, Aerts J, Arckens L, Saeys Y, Libert C, Vandenbroucke RE.

Mol Ther. 2016 May;24(5):890-902. doi: 10.1038/mt.2016.2. Epub 2016 Jan 18.


Amyloid β Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases.

Brkic M, Balusu S, Van Wonterghem E, Gorlé N, Benilova I, Kremer A, Van Hove I, Moons L, De Strooper B, Kanazir S, Libert C, Vandenbroucke RE.

J Neurosci. 2015 Sep 16;35(37):12766-78. doi: 10.1523/JNEUROSCI.0006-15.2015.


Synthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo.

Aerts J, Vandenbroucke RE, Dera R, Balusu S, Van Wonterghem E, Moons L, Libert C, Dehaen W, Arckens L.

Mediators Inflamm. 2015;2015:510679. doi: 10.1155/2015/510679. Epub 2015 Aug 13.


Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice.

Sklyarova T, van Hengel J, Van Wonterghem E, Libert C, van Roy F, Vandenbroucke RE.

Eur J Immunol. 2015 Oct;45(10):2898-910. doi: 10.1002/eji.201445440. Epub 2015 Aug 6.


Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

Vanden Berghe T, Hulpiau P, Martens L, Vandenbroucke RE, Van Wonterghem E, Perry SW, Bruggeman I, Divert T, Choi SM, Vuylsteke M, Shestopalov VI, Libert C, Vandenabeele P.

Immunity. 2015 Jul 21;43(1):200-9. doi: 10.1016/j.immuni.2015.06.011. Epub 2015 Jul 7.


Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation.

Dejager L, Dendoncker K, Eggermont M, Souffriau J, Van Hauwermeiren F, Willart M, Van Wonterghem E, Naessens T, Ballegeer M, Vandevyver S, Hammad H, Lambrecht B, De Bosscher K, Grooten J, Libert C.

Mucosal Immunol. 2015 Nov;8(6):1212-25. doi: 10.1038/mi.2015.12. Epub 2015 Mar 11.


Determining differentially expressed miRNAs and validating miRNA--target relationships using the SPRET/Ei mouse strain.

Timmermans S, Van Hauwermeiren F, Puimège L, Dejager L, Van Wonterghem E, Vanhooren V, Mestdagh P, Libert C, Vandenbroucke RE.

Mamm Genome. 2015 Feb;26(1-2):94-107. doi: 10.1007/s00335-014-9550-y. Epub 2014 Dec 10.


TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction.

Van Hauwermeiren F, Vandenbroucke RE, Grine L, Lodens S, Van Wonterghem E, De Rycke R, De Geest N, Hassan B, Libert C.

Mucosal Immunol. 2015 Jul;8(4):828-40. doi: 10.1038/mi.2014.112. Epub 2014 Nov 26.


Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock.

Vanden Berghe T, Demon D, Bogaert P, Vandendriessche B, Goethals A, Depuydt B, Vuylsteke M, Roelandt R, Van Wonterghem E, Vandenbroecke J, Choi SM, Meyer E, Krautwald S, Declercq W, Takahashi N, Cauwels A, Vandenabeele P.

Am J Respir Crit Care Med. 2014 Feb 1;189(3):282-91. doi: 10.1164/rccm.201308-1535OC.


Antisense oligonucleotides against TNFR1 prevent toxicity of TNF/IFNγ treatment in mouse tumor models.

Van Hauwermeiren F, Vandenbroucke RE, Grine L, Puimège L, Van Wonterghem E, Zhang H, Libert C.

Int J Cancer. 2014 Aug 1;135(3):742-50. doi: 10.1002/ijc.28704. Epub 2014 Jan 13.


Pharmacological inhibition of type I interferon signaling protects mice against lethal sepsis.

Dejager L, Vandevyver S, Ballegeer M, Van Wonterghem E, An LL, Riggs J, Kolbeck R, Libert C.

J Infect Dis. 2014 Mar;209(6):960-70. doi: 10.1093/infdis/jit600. Epub 2013 Nov 11.


Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation.

Vandenbroucke RE, Vanlaere I, Van Hauwermeiren F, Van Wonterghem E, Wilson C, Libert C.

Mucosal Immunol. 2014 May;7(3):579-88. doi: 10.1038/mi.2013.76. Epub 2013 Oct 16.


Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.

Vandenbroucke RE, Dejonckheere E, Van Hauwermeiren F, Lodens S, De Rycke R, Van Wonterghem E, Staes A, Gevaert K, López-Otin C, Libert C.

EMBO Mol Med. 2013 Jul;5(7):1000-16. doi: 10.1002/emmm.201202100. Epub 2013 May 30.


Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.

Vandenbroucke RE, Dejonckheere E, Van Lint P, Demeestere D, Van Wonterghem E, Vanlaere I, Puimège L, Van Hauwermeiren F, De Rycke R, Mc Guire C, Campestre C, López-Otin C, Matthys P, Leclercq G, Libert C.

J Neurosci. 2012 Jul 18;32(29):9805-16.

Supplemental Content

Loading ...
Support Center