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Items: 1 to 50 of 83

1.

Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques.

Eudailey JA, Dennis ML, Parker ME, Phillips BL, Huffman TN, Bay CP, Hudgens MG, Wiseman RW, Pollara JJ, Fouda GG, Ferrari G, Pickup DJ, Kozlowski PA, Van Rompay KKA, De Paris K, Permar SR.

mSphere. 2018 Jan 10;3(1). pii: e00505-17. doi: 10.1128/mSphere.00505-17. eCollection 2018 Jan-Feb.

2.

Early Sites of Virus Replication After Oral SIVmac251 Infection of Infant Macaques: Implications for Pathogenesis.

Amedee AM, Phillips B, Jensen K, Robichaux S, Lacour N, Burke M, Piatak M Jr., Lifson JD, Kozlowski PA, Van Rompay KKA, De Paris K.

AIDS Res Hum Retroviruses. 2018 Mar;34(3):286-299. doi: 10.1089/AID.2017.0169. Epub 2018 Jan 17.

PMID:
29237287
3.

IL-21 Therapy Controls Immune Activation and Maintains Antiviral CD8+ T Cell Responses in Acute Simian Immunodeficiency Virus Infection.

Méndez-Lagares G, Lu D, Merriam D, Baker CA, Villinger F, Van Rompay KKA, McCune JM, Hartigan-O'Connor DJ.

AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S81-S92. doi: 10.1089/aid.2017.0160.

PMID:
29140110
4.

Impact of Poxvirus Vector Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques.

Phillips B, Fouda GG, Eudailey J, Pollara J, Curtis AD 2nd, Kunz E, Dennis M, Shen X, Bay C, Hudgens M, Pickup D, Alam SM, Ardeshir A, Kozlowski PA, Van Rompay KKA, Ferrari G, Moody MA, Permar S, De Paris K.

Clin Vaccine Immunol. 2017 Oct 5;24(10). pii: e00231-17. doi: 10.1128/CVI.00231-17. Print 2017 Oct.

5.

HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques.

Han Q, Williams WB, Saunders KO, Seaton KE, Wiehe KJ, Vandergrift N, Von Holle TA, Trama AM, Parks RJ, Luo K, Gurley TC, Kepler TB, Marshall DJ, Montefiori DC, Sutherland LL, Alam MS, Whitesides JF, Bowman CM, Permar SR, Graham BS, Mascola JR, Seed PC, Van Rompay KKA, Tomaras GD, Moody MA, Haynes BF.

J Virol. 2017 Oct 13;91(21). pii: e00923-17. doi: 10.1128/JVI.00923-17. Print 2017 Nov 1.

6.

Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies.

Yee JL, Grant R, Van Rompay KK, Kuller L, Carpenter A, Watanabe R, Huebner R, Agricola B, Smedley J, Roberts JA.

J Med Primatol. 2017 Aug;46(4):149-153. doi: 10.1111/jmp.12295.

PMID:
28748661
7.

Tackling HIV and AIDS: contributions by non-human primate models.

Van Rompay KKA.

Lab Anim (NY). 2017 May 22;46(6):259-270. doi: 10.1038/laban.1279.

PMID:
28530684
8.

Hippocampal Neuronal Loss in Infant Macaques Orally Infected with Virulent Simian Immunodeficiency Virus (SIV).

Carryl H, Van Rompay KK, De Paris K, Burke MW.

Brain Sci. 2017 Apr 10;7(4). pii: E40. doi: 10.3390/brainsci7040040.

9.

Evidence of simian retrovirus type D by polymerase chain reaction.

Hwa CZR, Tsai SP, Yee JL, Van Rompay KK, Roberts JA.

J Med Primatol. 2017 Jun;46(3):79-86. doi: 10.1111/jmp.12266. Epub 2017 Mar 30.

PMID:
28370081
10.

Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques.

Coffey LL, Pesavento PA, Keesler RI, Singapuri A, Watanabe J, Watanabe R, Yee J, Bliss-Moreau E, Cruzen C, Christe KL, Reader JR, von Morgenland W, Gibbons AM, Allen AM, Linnen J, Gao K, Delwart E, Simmons G, Stone M, Lanteri M, Bakkour S, Busch M, Morrison J, Van Rompay KK.

PLoS One. 2017 Jan 31;12(1):e0171148. doi: 10.1371/journal.pone.0171148. eCollection 2017.

11.

Balancing Trained Immunity with Persistent Immune Activation and the Risk of Simian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine.

Jensen K, Dela Pena-Ponce MG, Piatak M Jr, Shoemaker R, Oswald K, Jacobs WR Jr, Fennelly G, Lucero C, Mollan KR, Hudgens MG, Amedee A, Kozlowski PA, Estes JD, Lifson JD, Van Rompay KK, Larsen M, De Paris K.

Clin Vaccine Immunol. 2017 Jan 5;24(1). pii: e00360-16. doi: 10.1128/CVI.00360-16. Print 2017 Jan.

12.

Engineering Paper-Based Sensors for Zika Virus.

Meagher RJ, Negrete OA, Van Rompay KK.

Trends Mol Med. 2016 Jul;22(7):529-530. doi: 10.1016/j.molmed.2016.05.009. Epub 2016 May 30.

PMID:
27255410
13.

Vaccine-Elicited Mucosal and Systemic Antibody Responses Are Associated with Reduced Simian Immunodeficiency Viremia in Infant Rhesus Macaques.

Jensen K, Nabi R, Van Rompay KKA, Robichaux S, Lifson JD, Piatak M Jr., Jacobs WR Jr., Fennelly G, Canfield D, Mollan KR, Hudgens MG, Larsen MH, Amedee AM, Kozlowski PA, De Paris K.

J Virol. 2016 Jul 27;90(16):7285-7302. doi: 10.1128/JVI.00481-16. Print 2016 Aug 15.

14.

Persistent effects of early infant diet and associated microbiota on the juvenile immune system.

Narayan NR, Méndez-Lagares G, Ardeshir A, Lu D, Van Rompay KK, Hartigan-O'Connor DJ.

Gut Microbes. 2015 Jul 4;6(4):284-9. doi: 10.1080/19490976.2015.1067743.

15.

Of mice and monkeys: can animal models be utilized to study neurological consequences of pediatric HIV-1 infection?

Carryl H, Swang M, Lawrence J, Curtis K, Kamboj H, Van Rompay KK, De Paris K, Burke MW.

ACS Chem Neurosci. 2015 Aug 19;6(8):1276-89. doi: 10.1021/acschemneuro.5b00044. Epub 2015 Jun 19. Review.

16.

The interplay between immune maturation, age, chronic viral infection and environment.

Oxford KL, Dela Pena-Ponce MGA, Jensen K, Eberhardt MK, Spinner A, Van Rompay KK, Rigdon J, Mollan KR, Krishnan VV, Hudgens MG, Barry PA, De Paris K.

Immun Ageing. 2015 May 9;12:3. doi: 10.1186/s12979-015-0030-3. eCollection 2015.

17.

Efficacy of HIV Postexposure Prophylaxis: Systematic Review and Meta-analysis of Nonhuman Primate Studies.

Irvine C, Egan KJ, Shubber Z, Van Rompay KK, Beanland RL, Ford N.

Clin Infect Dis. 2015 Jun 1;60 Suppl 3:S165-9. doi: 10.1093/cid/civ069. Review.

PMID:
25972498
18.

Binding of Complement Factor H (FH) Decreases Protective Anti-FH Binding Protein Antibody Responses of Infant Rhesus Macaques Immunized With a Meningococcal Serogroup B Vaccine.

Granoff DM, Costa I, Konar M, Giuntini S, Van Rompay KK, Beernink PT.

J Infect Dis. 2015 Sep 1;212(5):784-92. doi: 10.1093/infdis/jiv081. Epub 2015 Feb 12.

19.

Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems.

Ardeshir A, Narayan NR, Méndez-Lagares G, Lu D, Rauch M, Huang Y, Van Rompay KK, Lynch SV, Hartigan-O'Connor DJ.

Sci Transl Med. 2014 Sep 3;6(252):252ra120. doi: 10.1126/scitranslmed.3008791.

20.

Reduction of pyramidal and immature hippocampal neurons in pediatric simian immunodeficiency virus infection.

Curtis K, Rollins M, Carryl H, Bradshaw K, Van Rompay KK, Abel K, Burke MW.

Neuroreport. 2014 Sep 10;25(13):973-8. doi: 10.1097/WNR.0000000000000148. Erratum in: Neuroreport. 2014 Dec 17;25(18):1459. Kimberley, Bradshaw [corrected to Bradshaw, Kimberly].

21.

Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.

Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North TW.

PLoS One. 2014 Jan 31;9(1):e86997. doi: 10.1371/journal.pone.0086997. eCollection 2014.

22.

A neonatal oral Mycobacterium tuberculosis-SIV prime / intramuscular MVA-SIV boost combination vaccine induces both SIV and Mtb-specific immune responses in infant macaques.

Jensen K, Pena MG, Wilson RL, Ranganathan UD, Jacobs WR Jr, Fennelly G, Larsen M, Van Rompay KK, Kozlowski PA, Abel K.

Trials Vaccinol. 2013 Nov 1;2:53-63.

23.

A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251.

Van Rompay KK, Hunter Z, Jayashankar K, Peabody J, Montefiori D, LaBranche CC, Keele BF, Jensen K, Abel K, Chackerian B.

J Virol. 2014 Feb;88(4):2011-24. doi: 10.1128/JVI.02447-13. Epub 2013 Dec 4.

24.

Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.

Van Rompay KK, Trott KA, Jayashankar K, Geng Y, LaBranche CC, Johnson JA, Landucci G, Lipscomb J, Tarara RP, Canfield DR, Heneine W, Forthal DN, Montefiori D, Abel K.

Retrovirology. 2012 Jul 17;9:57. doi: 10.1186/1742-4690-9-57.

25.

Compared to subcutaneous tenofovir, oral tenofovir disoproxyl fumarate administration preferentially concentrates the drug into gut-associated lymphoid cells in simian immunodeficiency virus-infected macaques.

Van Rompay KK, Babusis D, Abbott Z, Geng Y, Jayashankar K, Johnson JA, Lipscomb J, Heneine W, Abel K, Ray AS.

Antimicrob Agents Chemother. 2012 Sep;56(9):4980-4. doi: 10.1128/AAC.01095-12. Epub 2012 Jul 9.

26.

A recombinant attenuated Mycobacterium tuberculosis vaccine strain is safe in immunosuppressed simian immunodeficiency virus-infected infant macaques.

Jensen K, Ranganathan UD, Van Rompay KK, Canfield DR, Khan I, Ravindran R, Luciw PA, Jacobs WR Jr, Fennelly G, Larsen MH, Abel K.

Clin Vaccine Immunol. 2012 Aug;19(8):1170-81. doi: 10.1128/CVI.00184-12. Epub 2012 Jun 13.

27.

SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment.

Hartigan-O'Connor DJ, Abel K, Van Rompay KK, Kanwar B, McCune JM.

Sci Transl Med. 2012 May 30;4(136):136ra69. doi: 10.1126/scitranslmed.3003941.

28.

Animal models of HIV transmission through breastfeeding and pediatric HIV infection.

Van Rompay KK, Jayashankar K.

Adv Exp Med Biol. 2012;743:89-108. doi: 10.1007/978-1-4614-2251-8_7. No abstract available.

PMID:
22454344
29.

The use of nonhuman primate models of HIV infection for the evaluation of antiviral strategies.

Van Rompay KK.

AIDS Res Hum Retroviruses. 2012 Jan;28(1):16-35. doi: 10.1089/AID.2011.0234. Epub 2011 Oct 19. Review.

PMID:
21902451
30.

Pharmacokinetics and safety of single-dose tenofovir disoproxil fumarate and emtricitabine in HIV-1-infected pregnant women and their infants.

Flynn PM, Mirochnick M, Shapiro DE, Bardeguez A, Rodman J, Robbins B, Huang S, Fiscus SA, Van Rompay KK, Rooney JF, Kearney B, Mofenson LM, Watts DH, Jean-Philippe P, Heckman B, Thorpe E Jr, Cotter A, Purswani M; PACTG 394 Study Team.

Antimicrob Agents Chemother. 2011 Dec;55(12):5914-22. doi: 10.1128/AAC.00544-11. Epub 2011 Sep 6.

31.

Partial efficacy of a VSV-SIV/MVA-SIV vaccine regimen against oral SIV challenge in infant macaques.

Marthas ML, Van Rompay KK, Abbott Z, Earl P, Buonocore-Buzzelli L, Moss B, Rose NF, Rose JK, Kozlowski PA, Abel K.

Vaccine. 2011 Apr 12;29(17):3124-37. doi: 10.1016/j.vaccine.2011.02.051. Epub 2011 Mar 4.

32.

Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency virus.

von Gegerfelt A, Valentin A, Alicea C, Van Rompay KK, Marthas ML, Montefiori DC, Pavlakis GN, Felber BK.

J Immunol. 2010 Sep 15;185(6):3348-58. doi: 10.4049/jimmunol.1000572. Epub 2010 Aug 11.

33.

Maternal-fetal pharmacokinetics and dynamics of a single intrapartum dose of maraviroc in rhesus macaques.

Winters MA, Van Rompay KK, Kashuba AD, Shulman NS, Holodniy M.

Antimicrob Agents Chemother. 2010 Oct;54(10):4059-63. doi: 10.1128/AAC.00747-10. Epub 2010 Aug 9.

34.

Immunogenicity of viral vector, prime-boost SIV vaccine regimens in infant rhesus macaques: attenuated vesicular stomatitis virus (VSV) and modified vaccinia Ankara (MVA) recombinant SIV vaccines compared to live-attenuated SIV.

Van Rompay KK, Abel K, Earl P, Kozlowski PA, Easlick J, Moore J, Buonocore-Buzzelli L, Schmidt KA, Wilson RL, Simon I, Moss B, Rose N, Rose J, Marthas ML.

Vaccine. 2010 Feb 10;28(6):1481-92. doi: 10.1016/j.vaccine.2009.11.061. Epub 2009 Dec 6.

35.

DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge.

Rosati M, Bergamaschi C, Valentin A, Kulkarni V, Jalah R, Alicea C, Patel V, von Gegerfelt AS, Montefiori DC, Venzon DJ, Khan AS, Draghia-Akli R, Van Rompay KK, Felber BK, Pavlakis GN.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15831-6. doi: 10.1073/pnas.0902628106. Epub 2009 Aug 28.

36.

Evaluation of antiretrovirals in animal models of HIV infection.

Van Rompay KK.

Antiviral Res. 2010 Jan;85(1):159-75. doi: 10.1016/j.antiviral.2009.07.008. Epub 2009 Jul 19. Review.

PMID:
19622373
37.

Nucleotide analogue prodrug tenofovir disoproxil enhances lymphoid cell loading following oral administration in monkeys.

Durand-Gasselin L, Van Rompay KK, Vela JE, Henne IN, Lee WA, Rhodes GR, Ray AS.

Mol Pharm. 2009 Jul-Aug;6(4):1145-51. doi: 10.1021/mp900036s.

38.

Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects.

Van Rompay KK, Durand-Gasselin L, Brignolo LL, Ray AS, Abel K, Cihlar T, Spinner A, Jerome C, Moore J, Kearney BP, Marthas ML, Reiser H, Bischofberger N.

Antimicrob Agents Chemother. 2008 Sep;52(9):3144-60. doi: 10.1128/AAC.00350-08. Epub 2008 Jun 23.

39.

Empowering the people: development of an HIV peer education model for low literacy rural communities in India.

Van Rompay KK, Madhivanan P, Rafiq M, Krupp K, Chakrapani V, Selvam D.

Hum Resour Health. 2008 Apr 18;6:6. doi: 10.1186/1478-4491-6-6.

40.

Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection.

Van Rompay KK, Johnson JA, Blackwood EJ, Singh RP, Lipscomb J, Matthews TB, Marthas ML, Pedersen NC, Bischofberger N, Heneine W, North TW.

Retrovirology. 2007 Apr 6;4:25.

41.

Evaluation of passively transferred, nonneutralizing antibody-dependent cellular cytotoxicity-mediating IgG in protection of neonatal rhesus macaques against oral SIVmac251 challenge.

Florese RH, Van Rompay KK, Aldrich K, Forthal DN, Landucci G, Mahalanabis M, Haigwood N, Venzon D, Kalyanaraman VS, Marthas ML, Robert-Guroff M.

J Immunol. 2006 Sep 15;177(6):4028-36.

42.

Evaluation of oral tenofovir disoproxil fumarate and topical tenofovir GS-7340 to protect infant macaques against repeated oral challenges with virulent simian immunodeficiency virus.

Van Rompay KK, Kearney BP, Sexton JJ, Colón R, Lawson JR, Blackwood EJ, Lee WA, Bischofberger N, Marthas ML.

J Acquir Immune Defic Syndr. 2006 Sep;43(1):6-14.

PMID:
16810108
43.

Long lasting control and lack of pathogenicity of the attenuated Rev-independent SIV in rhesus macaques.

von Gegerfelt AS, Alicea C, Valentin A, Morrow M, van Rompay KK, Ayash-Rashkovsky M, Markham P, Else JG, Marthas ML, Pavlakis GN, Ruprecht RM, Felber BK.

AIDS Res Hum Retroviruses. 2006 Jun;22(6):516-28.

PMID:
16796527
44.

Structured treatment interruptions with tenofovir monotherapy for simian immunodeficiency virus-infected newborn macaques.

Van Rompay KK, Singh RP, Heneine W, Johnson JA, Montefiori DC, Bischofberger N, Marthas ML.

J Virol. 2006 Jul;80(13):6399-410.

45.

Rapid virus dissemination in infant macaques after oral simian immunodeficiency virus exposure in the presence of local innate immune responses.

Abel K, Pahar B, Van Rompay KK, Fritts L, Sin C, Schmidt K, Colón R, McChesney M, Marthas ML.

J Virol. 2006 Jul;80(13):6357-67.

46.

Role of CD8+ cells in controlling replication of nonpathogenic Simian Immunodeficiency Virus SIVmac1A11.

Van Rompay KK, Blackwood EJ, Landucci G, Forthal D, Marthas ML.

Virol J. 2006 Apr 3;3:22.

49.

Pharmacokinetics of tenofovir in breast milk of lactating rhesus macaques.

Van Rompay KK, Hamilton M, Kearney B, Bischofberger N.

Antimicrob Agents Chemother. 2005 May;49(5):2093-4.

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