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Items: 13


Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.

Steeland S, Gorlé N, Vandendriessche C, Balusu S, Brkic M, Van Cauwenberghe C, Van Imschoot G, Van Wonterghem E, De Rycke R, Kremer A, Lippens S, Stopa E, Johanson CE, Libert C, Vandenbroucke RE.

EMBO Mol Med. 2018 Feb 22. pii: e8300. doi: 10.15252/emmm.201708300. [Epub ahead of print]


Quantifying the Average Number of Nucleic Acid Therapeutics per Nanocarrier by Single Particle Tracking Microscopy.

Zagato E, Vermeulen L, Dewitte H, Van Imschoot G, Vandenbroucke RE, Demeester J, De Smedt SC, Neyts K, Remaut K, Braeckmans K.

Mol Pharm. 2018 Mar 5;15(3):1142-1149. doi: 10.1021/acs.molpharmaceut.7b00999. Epub 2018 Feb 19.


The choroid plexus epithelium as a novel player in the stomach-brain axis during Helicobacter infection.

Gorlé N, Blaecher C, Bauwens E, Vandendriessche C, Balusu S, Vandewalle J, Van Cauwenberghe C, Van Wonterghem E, Van Imschoot G, Liu C, Ducatelle R, Libert C, Haesebrouck F, Smet A, Vandenbroucke RE.

Brain Behav Immun. 2018 Mar;69:35-47. doi: 10.1016/j.bbi.2017.12.010. Epub 2017 Dec 16.


TNFR1 inhibition with a Nanobody protects against EAE development in mice.

Steeland S, Van Ryckeghem S, Van Imschoot G, De Rycke R, Toussaint W, Vanhoutte L, Vanhove C, De Vos F, Vandenbroucke RE, Libert C.

Sci Rep. 2017 Oct 20;7(1):13646. doi: 10.1038/s41598-017-13984-y.


Caspase-9 has a nonapoptotic function in Xenopus embryonic primitive blood formation.

Tran HT, Fransen M, Dimitrakopoulou D, Van Imschoot G, Willemarck N, Vleminckx K.

J Cell Sci. 2017 Jul 15;130(14):2371-2381. doi: 10.1242/jcs.186411. Epub 2017 Jun 2.


Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8.

Demeestere D, Dejonckheere E, Steeland S, Hulpiau P, Haustraete J, Devoogdt N, Wichert R, Becker-Pauly C, Van Wonterghem E, Dewaele S, Van Imschoot G, Aerts J, Arckens L, Saeys Y, Libert C, Vandenbroucke RE.

Mol Ther. 2016 May;24(5):890-902. doi: 10.1038/mt.2016.2. Epub 2016 Jan 18.


Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase.

De Groef L, Salinas-Navarro M, Van Imschoot G, Libert C, Vandenbroucke RE, Moons L.

Mediators Inflamm. 2015;2015:108617. doi: 10.1155/2015/108617. Epub 2015 Sep 15.


TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis.

Van Nieuwenhuysen T, Naert T, Tran HT, Van Imschoot G, Geurs S, Sanders E, Creytens D, Van Roy F, Vleminckx K.

Oncoscience. 2015 May 19;2(5):555-66. eCollection 2015.


A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes.

De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guérin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W.

Cell Death Differ. 2015 Jun;22(6):1012-24. doi: 10.1038/cdd.2014.191. Epub 2014 Nov 28.


Aberrant activation of fatty acid synthesis suppresses primary cilium formation and distorts tissue development.

Willemarck N, Rysman E, Brusselmans K, Van Imschoot G, Vanderhoydonc F, Moerloose K, Lerut E, Verhoeven G, van Roy F, Vleminckx K, Swinnen JV.

Cancer Res. 2010 Nov 15;70(22):9453-62. doi: 10.1158/0008-5472.CAN-10-2324. Epub 2010 Oct 1.


Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo.

Tran HT, Sekkali B, Van Imschoot G, Janssens S, Vleminckx K.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16160-5. doi: 10.1073/pnas.1007725107. Epub 2010 Aug 30.


p120 catenin is required for morphogenetic movements involved in the formation of the eyes and the craniofacial skeleton in Xenopus.

Ciesiolka M, Delvaeye M, Van Imschoot G, Verschuere V, McCrea P, van Roy F, Vleminckx K.

J Cell Sci. 2004 Aug 15;117(Pt 18):4325-39. Epub 2004 Aug 3.

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